C Oppenheim


Affiliation: Centre Hospitalier Sainte-Anne
Country: France


  1. Legrand L, Turc G, Edjlali M, Beaumont M, Gautheron V, Ben Hassen W, et al. Benefit from revascularization after thrombectomy according to FLAIR vascular hyperintensities-DWI mismatch. Eur Radiol. 2019;: pubmed publisher
    ..FVH-DWI mismatch provides an alternative to PWI-DWI mismatch in order to select patients who are candidates for thrombectomy. ..
  2. Legrand L, Tisserand M, Turc G, Naggara O, Edjlali M, Mellerio C, et al. Do FLAIR vascular hyperintensities beyond the DWI lesion represent the ischemic penumbra?. AJNR Am J Neuroradiol. 2015;36:269-74 pubmed publisher
    ..001). Albeit being moderately specific, probably due to inclusion of oligemic tissue, the FLAIR vascular hyperintensity-DWI mismatch identifies large PWI-DWI mismatch with high sensitivity. ..
  3. Danière F, Edjlali Goujon M, Mellerio C, Turc G, Naggara O, Tselikas L, et al. MR screening of candidates for thrombolysis: How to identify stroke mimics?. J Neuroradiol. 2014;41:283-95 pubmed publisher
    ..The issues linked to the accurate diagnosis of stroke mimics in the management of candidates for thrombolysis will be discussed. ..
  4. Soize S, Tisserand M, Charron S, Turc G, Ben Hassen W, Labeyrie M, et al. How sustained is 24-hour diffusion-weighted imaging lesion reversal? Serial magnetic resonance imaging in a patient cohort thrombolyzed within 4.5 hours of stroke onset. Stroke. 2015;46:704-10 pubmed publisher
    ..03). After thrombolysis, over two-thirds of the DWI lesion reversal captured on 24-hour follow-up MR is sustained. Sustained DWI lesion reversal volume is a strong imaging correlate of early neurological improvement. ..
  5. Souillard Scemama R, Tisserand M, Calvet D, Jumadilova D, Lion S, Turc G, et al. An update on brain imaging in transient ischemic attack. J Neuroradiol. 2015;42:3-11 pubmed publisher
    ..Rapid etiological work-up includes non-invasive imaging of cervical and intracranial arteries to search for symptomatic stenosis/occlusion associated with an increased risk of stroke. ..
  6. Dautry R, Edjlali M, Roca P, Rabrait C, Wu Y, Johnson K, et al. Interest of HYPR flow dynamic MRA for characterization of cerebral arteriovenous malformations: comparison with TRICKS MRA and catheter DSA. Eur Radiol. 2015;25:3230-7 pubmed publisher
  7. Hassen W, Tisserand M, Turc G, Charron S, Seners P, Edjlali M, et al. Comparison between voxel-based and subtraction methods for measuring diffusion-weighted imaging lesion growth after thrombolysis. Int J Stroke. 2016;11:221-8 pubmed publisher
    ..2% of patients. Although more time-consuming, the voxel-based method may impact results of trials that use infarct growth attenuation as an end-point. ..
  8. Legrand L, Tisserand M, Turc G, Edjlali M, Calvet D, Trystram D, et al. Fluid-Attenuated Inversion Recovery Vascular Hyperintensities-Diffusion-Weighted Imaging Mismatch Identifies Acute Stroke Patients Most Likely to Benefit From Recanalization. Stroke. 2016;47:424-7 pubmed publisher
    ..0; 95% confidence interval, 1.1-44.1; P=0.047), P=0.76 for interaction. The FVH-DWI mismatch may rapidly identify patients with proximal occlusion most likely to benefit from recanalization. ..
  9. Lassalle L, Turc G, Tisserand M, Charron S, Roca P, Lion S, et al. ASPECTS (Alberta Stroke Program Early CT Score) Assessment of the Perfusion-Diffusion Mismatch. Stroke. 2016;47:2553-8 pubmed publisher
    ..It could be used for rapid screening of patients with eligible mismatch, in centers not equipped with ultrafast postprocessing software. ..

More Information


  1. Benzakoun J, Maier B, Calvet D, Edjlali M, Turc G, Lion S, et al. Can a 15-sec FLAIR replace conventional FLAIR sequence in stroke MR protocols?. J Neuroradiol. 2017;44:192-197 pubmed publisher
    ..Compared with cFLAIR, it is however associated with increased risk of undiagnosed stroke mimics and lower PPV for identifying<4.5-hrs infarctions. ..
  2. Gautheron V, Xie Y, Tisserand M, Raoult H, Soize S, Naggara O, et al. Outcome After Reperfusion Therapies in Patients With Large Baseline Diffusion-Weighted Imaging Stroke Lesions: A THRACE Trial (Mechanical Thrombectomy After Intravenous Alteplase Versus Alteplase Alone After Stroke) Subgroup Analysis. Stroke. 2018;49:750-753 pubmed publisher
    ..The benefit of treatment seems questionable for patients with carotid occlusion or lesion extending to the deep middle cerebral artery territory. ..
  3. Tisserand M, Turc G, Charron S, Legrand L, Edjlali M, Seners P, et al. Does Diffusion Lesion Volume Above 70 mL Preclude Favorable Outcome Despite Post-Thrombolysis Recanalization?. Stroke. 2016;47:1005-11 pubmed publisher
    ..5], respectively; P=0.049). Patients with DWI lesion volume ≥70 mL can benefit from recanalization after intravenous recombinant tissue-type plasminogen activator. This may partly reflect a larger amount of DWI lesion reversal. ..
  4. Mahdjoub E, Turc G, Legrand L, Benzakoun J, Edjlali M, Seners P, et al. Do Fluid-Attenuated Inversion Recovery Vascular Hyperintensities Represent Good Collaterals before Reperfusion Therapy?. AJNR Am J Neuroradiol. 2018;39:77-83 pubmed publisher
    ..The ASPECTS assessment of FLAIR vascular hyperintensities could be used to rapidly identify patients more likely to benefit from reperfusion therapy. ..