Research Topics
Genomes and GenesSpecies | F LebertSummaryAffiliation: Centre Hospitalier de Valenciennes Country: France Publications
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Detail Information
Publications
Frontotemporal dementia: a randomised, controlled trial with trazodoneFlorence Lebert
Memory Clinic, Lille University Hospital, Lille, France
Dement Geriatr Cogn Disord 17:355-9. 2004..The Mini-Mental State Examination was not modified and trazodone was well tolerated. Results of this first placebo-controlled trial suggest that trazodone is an effective treatment for the behavioural symptoms of FTD...
[Treatment of psychiatric and behavioural symptoms in Alzheimer's disease]F Lebert
, , Bailleul
Rev Neurol (Paris) 159:825-30. 2003
Alzheimer disease with cerebrovascular disease and vascular dementia: clinical features and course compared with Alzheimer diseaseA Bruandet
INSERM, U744, Lille, France
J Neurol Neurosurg Psychiatry 80:133-9. 2009..Little is known about the progression of either VaD or AD+CVD. The aim of this study was to compare demographic features, cognitive decline and survival of patients with VaD, AD+CVD and AD alone attending a memory clinic...
Prediction of pathology in primary progressive language and speech disordersV Deramecourt
Memory Clinic, EA 2691, CHRU Lille F 59037 Lille, France
Neurology 74:42-9. 2010..This study sought to characterize correlations between 1) the different clinical variants of primary progressive language and speech disorders and 2) the pathologic diagnosis...
Memory impairment differs in frontotemporal dementia and Alzheimer's diseaseF Pasquier
Memory Centre, Department of Neurology, University Hospital of Lille, Lille, France
Neurocase 7:161-71. 2001..AD patients with clinical and imaging frontal lobe dysfunction tended to have lower memory performance and to differ even more from FTD patients than AD patients without frontal lobe dysfunction...
The clinical picture of frontotemporal dementia: diagnosis and follow-upF Pasquier
Memory Clinic, Centre Hospitalier et Universitaire, Lille, France
Dement Geriatr Cogn Disord 10:10-4. 1999..Behavioural disorders evolved with time but restlessness and hyperorality were long-lasting. Imaging showed the progression of a consistent pattern of anterior abnormalities with frequent leukoaraiosis...
Tacrine efficacy in Lewy body dementiaF Lebert
Memory Clinic, Centre Hospitalier Universitaire and Faculté de Médecine, Lille, France
Int J Geriatr Psychiatry 13:516-9. 1998..Response to tacrine varies among patients with Alzheimer's disease (AD). Lewy body dementia (LBD) could be a high responder subtype of AD. The aim of the study was to compare the effects of tacrine in LBD and AD...
[Dementia following bipolar disorder]F Lebert
EA2691, centre de la mémoire de ressources et de recherche, Hopital R Salengro, CHRU de Lille, Lille, France
Encephale 34:606-10. 2008..In old age BPD, the cognitive decline is more severe and can fulfill the criteria of dementia. However, the characteristics of bipolar disorder dementia are still unknown...
[Serotonin reuptake inhibitors in depression of Alzheimer's disease and other dementias]Florence Lebert
, , CHRU Lille, Bailleul
Presse Med 32:1181-6. 2003..Efficacy of SSRI in patients with Lewy body dementia remains to be confirmed...
Depressive symptoms after stroke and relationship with dementia: A three-year follow-up studyA Verdelho
Stroke Department and Memory Clinic, Department of Neurology, University of Lille, Roger Salengro Hospital, Lille, France
Neurology 62:905-11. 2004..CONCLUSION: DS are frequent after stroke. Their time course varies and depends on the cognitive status; this variation contributes to differences among previous studies on poststroke depression...
Biochemical staging of synucleinopathy and amyloid deposition in dementia with Lewy bodiesV Deramecourt
Inserm Unit 815, Lille, France
J Neuropathol Exp Neurol 65:278-88. 2006..The constant and abundant Abeta x-42 deposition in sporadic DLB suggests that synucleinopathy is also promoted by APP dysfunction. Therefore, we conclude that APP is a therapeutic target for both AD and DLB...
Natural history of frontotemporal dementia: comparison with Alzheimer's diseaseFlorence Pasquier
Memory Clinic, University Hospital, EA 2691, and INSERM U 508, Lille, France
Dement Geriatr Cogn Disord 17:253-7. 2004..Frontotemporal dementia (FTD) is a more common cause of dementia than previously recognised. Few data are available regarding the natural course of FTD in terms of survival, nursing home admission and causes of death...
[Frontotemporal dementia: behavioral story of a neurological disease]Florence Lebert
Centre de la Mémoire, Hopital Salengro, CHRU de Lille, France
Psychol Neuropsychiatr Vieil 6:33-41. 2008..However, over time, the occurrence of mutism may lead caregivers to regret the period of behavioral disorders...
[Treatment of frontotemporal dementia]Florence Lebert
Centre de la Mémoire, Hopital Salengro, CHRU Lille
Psychol Neuropsychiatr Vieil 2:35-42. 2004..The recognition of the differences between FTD and Alzheimer's disease allows to determine a specific management of FTD patients and their caregivers...
[Treatment of Alzheimer's disease]Stephanie Bombois
centre mémoire de ressource et de recherche, EA 2691, CHRU de Lille, 59037 Lille
Rev Prat 55:1913-9. 2005..However, AD represents a problem of public health and preventive and curative strategies have to be proposed...
Patients characteristics with cholinesterase inhibitor resistant hallucinations in dementia with Lewy bodiesFlorence Lebert
J Neurol Neurosurg Psychiatry 78:1415-6. 2007
Diogene syndrome, a clinical presentation of fronto-temporal dementia or not?Florence Lebert
Int J Geriatr Psychiatry 20:1203-4. 2005
Tau aggregation in the hippocampal formation: an ageing or a pathological process?Andre Delacourte
Unite INSERM 422, 1, Place de Verdun, 59045 Lille Cedex, France
Exp Gerontol 37:1291-6. 2002..Tauopathy in the entorhinal and hippocampal formation could be another type of pathological dysfunction of tau proteins, and a therapeutic target to delay AD. Relevant animal models are desperately needed to address this issue...
Influence of prestroke dementia on early and delayed mortality in stroke patientsHilde Henon
Department of Neurology, Hopital Roger Salengro, CHRU of Lille, 59037 Lille, France
J Neurol 250:10-6. 2003..Dementia adversely influences vital outcome in stroke patients, perhaps partly because the therapeutic approach differs between demented and non-demented patients...
