Emilie Le Rhun

Summary

Affiliation: Centre Oscar Lambret
Country: France

Publications

  1. doi request reprint A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy
    Emilie Le Rhun
    Neurology, Breast Cancer Unit, Oscar Lambret Center, 3 Rue Frederic Combemale, 59 020, Lille Cedex, France
    Breast Cancer Res Treat 152:569-80. 2015
  2. pmc Treatment patterns, clinical outcomes and health care costs associated with HER2-positive breast cancer with central nervous system metastases: a French multicentre observational study
    Sandrine Baffert
    Department of Public Health, Health Economics Unit, Institut Curie, 26 Rue d Ulm, Paris 75005, France
    BMC Health Serv Res 13:456. 2013
  3. ncbi request reprint Prolonged survival of patients with breast cancer-related leptomeningeal metastases
    Emilie Le Rhun
    Breast Unit, Department of Medical Oncology, Oscar Lambret Center, Lille Cedex, France
    Anticancer Res 33:2057-63. 2013
  4. doi request reprint Detection and quantification of CSF malignant cells by the CellSearch technology in patients with melanoma leptomeningeal metastasis
    Emilie Le Rhun
    Neurology, Breast Unit, Department of Medical Oncology, Oscar Lambret Center, 3 Rue F Combemale, 59020 Lille Cedex, France
    Med Oncol 30:538. 2013
  5. doi request reprint Clinicopathological features of breast cancers predict the development of leptomeningeal metastases: a case-control study
    Emilie Le Rhun
    Neurology Breast Unit, Department of Medical Oncology, Centre Oscar Lambret, 59037, Lille Cedex, France
    J Neurooncol 105:309-15. 2011
  6. pmc Development of a new method for identification and quantification in cerebrospinal fluid of malignant cells from breast carcinoma leptomeningeal metastasis
    Emilie Le Rhun
    Neurology, Breast Unit, Deparment of Medical Oncology, Oscar Lambret Center, Lille, France and Neuro oncology, University Hospital, Lille, France
    BMC Clin Pathol 12:21. 2012
  7. ncbi request reprint Leptomeningeal metastasis in melanoma: a prospective clinical study of nine patients
    Emeline Pape
    Department of Dermatology, Huriez Hospital, Regional and University Hospital, Lille, France
    In Vivo 26:1079-86. 2012
  8. doi request reprint Complications related to the use of an intraventricular access device for the treatment of leptomeningeal metastases from solid tumor: a single centre experience in 112 patients
    Fahed Zairi
    Department of Neurosurgery, Hopital Roger Salengro, Lille University Hospital, Rue Emile Laine, 59037, Lille, France
    J Neurooncol 124:317-23. 2015
  9. doi request reprint CSF CA 15-3 in breast cancer-related leptomeningeal metastases
    Emilie Le Rhun
    Breast Unit, Department of Medical Oncology, Oscar Lambret Center, 59 020, Lille Cedex, France
    J Neurooncol 117:117-24. 2014
  10. doi request reprint Securing the circuit of intrathecally administered cancer drugs: example of a collective approach
    Guillaume Marliot
    Département de Pharmacie Clinique, Centre Oscar Lambret, Lille, France
    J Oncol Pharm Pract 17:252-9. 2011

Collaborators

Detail Information

Publications19

  1. doi request reprint A phase III randomized multicenter trial evaluating cognition in post-menopausal breast cancer patients receiving adjuvant hormonotherapy
    Emilie Le Rhun
    Neurology, Breast Cancer Unit, Oscar Lambret Center, 3 Rue Frederic Combemale, 59 020, Lille Cedex, France
    Breast Cancer Res Treat 152:569-80. 2015
    ..In this study, AI has not demonstrated worse adverse effects on cognitive functions than tamoxifen during a 1-year follow-up...
  2. pmc Treatment patterns, clinical outcomes and health care costs associated with HER2-positive breast cancer with central nervous system metastases: a French multicentre observational study
    Sandrine Baffert
    Department of Public Health, Health Economics Unit, Institut Curie, 26 Rue d Ulm, Paris 75005, France
    BMC Health Serv Res 13:456. 2013
    ..Treatment strategies in this population are highly diverse. The objective of the study was to assess health care costs for the management of HER2 positive BC with CNS metastases...
  3. ncbi request reprint Prolonged survival of patients with breast cancer-related leptomeningeal metastases
    Emilie Le Rhun
    Breast Unit, Department of Medical Oncology, Oscar Lambret Center, Lille Cedex, France
    Anticancer Res 33:2057-63. 2013
    ..The management and treatment of such patients is poorly-described. We report our experience on breast cancer (BC)-associated LM and patients with prolonged survival...
  4. doi request reprint Detection and quantification of CSF malignant cells by the CellSearch technology in patients with melanoma leptomeningeal metastasis
    Emilie Le Rhun
    Neurology, Breast Unit, Department of Medical Oncology, Oscar Lambret Center, 3 Rue F Combemale, 59020 Lille Cedex, France
    Med Oncol 30:538. 2013
    ..This methodology, established on a limited volume of sample and allowing delayed processing, could prove of great interest in the diagnosis and follow-up of melanoma patients with LM...
  5. doi request reprint Clinicopathological features of breast cancers predict the development of leptomeningeal metastases: a case-control study
    Emilie Le Rhun
    Neurology Breast Unit, Department of Medical Oncology, Centre Oscar Lambret, 59037, Lille Cedex, France
    J Neurooncol 105:309-15. 2011
    ..These characteristics should lead to early appropriate assessments being performed in this targeted population when a neurological complaint appears, in order to detect LM as soon as possible...
  6. pmc Development of a new method for identification and quantification in cerebrospinal fluid of malignant cells from breast carcinoma leptomeningeal metastasis
    Emilie Le Rhun
    Neurology, Breast Unit, Deparment of Medical Oncology, Oscar Lambret Center, Lille, France and Neuro oncology, University Hospital, Lille, France
    BMC Clin Pathol 12:21. 2012
    ..abstract:..
  7. ncbi request reprint Leptomeningeal metastasis in melanoma: a prospective clinical study of nine patients
    Emeline Pape
    Department of Dermatology, Huriez Hospital, Regional and University Hospital, Lille, France
    In Vivo 26:1079-86. 2012
    ..This article describes recent experience at the Lille University Hospital, between 2007 and 2011 and discusses the possibilities for treatment of leptomeningeal metastasis...
  8. doi request reprint Complications related to the use of an intraventricular access device for the treatment of leptomeningeal metastases from solid tumor: a single centre experience in 112 patients
    Fahed Zairi
    Department of Neurosurgery, Hopital Roger Salengro, Lille University Hospital, Rue Emile Laine, 59037, Lille, France
    J Neurooncol 124:317-23. 2015
    ..8 complications required an operation and 1 complication was fatal. The use of a VAD is safe and may improve patients' comfort and compliance with LM-directed therapy. ..
  9. doi request reprint CSF CA 15-3 in breast cancer-related leptomeningeal metastases
    Emilie Le Rhun
    Breast Unit, Department of Medical Oncology, Oscar Lambret Center, 59 020, Lille Cedex, France
    J Neurooncol 117:117-24. 2014
    ..Additionally, the CSF/serum ratio of CA 15-3 was significantly higher in this group of patients (median 0.18, range 0.002-4.40). Multivariate analysis identified a cut-off for CSF CA15-3 with 80 % sensitivity and 70 % specificity...
  10. doi request reprint Securing the circuit of intrathecally administered cancer drugs: example of a collective approach
    Guillaume Marliot
    Département de Pharmacie Clinique, Centre Oscar Lambret, Lille, France
    J Oncol Pharm Pract 17:252-9. 2011
    ..This multidisciplinary approach to improve our practices complements the precautions taken by healthcare teams...
  11. doi request reprint Complications related to the placement of an intraventricular chemotherapy device
    Fahed Zairi
    Department of Neurosurgery, Lille University Hospital, Lille, France
    J Neurooncol 104:247-52. 2011
    ..There was no case of misplacement or obstruction of the catheter. Intraventricular chemotherapy is an effective treatment procedure which improves therapeutic compliance with acceptable morbidity...
  12. doi request reprint Current Management of Adult Diffuse Infiltrative Low Grade Gliomas
    Emilie Le Rhun
    Neuro Oncology, Department of Neurosurgery, Lille University Hospital, Lille, France
    Curr Neurol Neurosci Rep 16:15. 2016
    ..The integration of molecular biomarkers with histology will lead to an improved classification that more accurately reflects underlying tumor biology, prognosis, and hopefully best therapy. ..
  13. doi request reprint Tumor treating fields: a new standard treatment for glioblastoma?
    Sophie Taillibert
    aDepartment of Neurology bDepartment of Radiation Oncology, Pitie Salpetriere Hospital, UPMC Paris VI University, Paris cNeuro oncology, Department of Neurosurgery, University Hospital dBreast Unit, Department of Medical Oncology, Oscar Lambret Center, Lille Cedex ePRISM Inserm U1191, Villeneuve d Ascq, France fDepartment of Neurology, Fred Hutchinson Cancer Research Center, Seattle Cancer Care Alliance, University of Washington, Seattle, Washington, USA
    Curr Opin Neurol 28:659-64. 2015
    ....
  14. doi request reprint Anaplastic glioma: current treatment and management
    Emilie Le Rhun
    Department of Neuro Oncology, Roger Salengro Hospital, University Hospital, Lille, France
    Expert Rev Neurother 15:601-20. 2015
    ..Maturation of NOA-04 and results of the currently accruing studies, CODEL (for codeleted AG) and CATNON (for uni or non-codeleted AG), will likely refine current up-front treatment recommendations for AG. ..
  15. pmc Carcinomatous meningitis: Leptomeningeal metastases in solid tumors
    Emilie Le Rhun
    Breast Unit, Department of Medical Oncology, Centre Oscar Lambret and Department of Neuro Oncology, Roger Salengro Hospital, University Hospital, Lille, France
    Surg Neurol Int 4:S265-88. 2013
    ..Challenges of managing patients with LM are manifold and include determining the appropriate patients for treatment as well as the optimal route of administration of intra-CSF drug therapy...
  16. doi request reprint Febrile neutropenia incidence and hematological toxicity with the FEC100-docetaxel regimen in the treatment of early-stage breast cancer
    Sophie Cousin
    Centre Oscar Lambret, département sénologie, Lille, France
    Bull Cancer 99:75-80. 2012
    ..Because FEC100-docetaxel (FEC100-D) is a common protocol for ESBC, we evaluated its febrile neutropenia (FN) incidence and the role of its hematological toxicity on the individual relative dose-intensity (RDI)...
  17. doi request reprint Parvovirus H-1 induces cytopathic effects in breast carcinoma-derived cultures
    Ghaffar Muharram
    CNRS, UMR 8161, Institut de Biologie de Lille, Lille Cedex, France
    Breast Cancer Res Treat 121:23-33. 2010
    ..It identifies tumor characteristics representing potential criteria for recruiting patients for clinical evaluation of H-1 PV antitumor effects...
  18. doi request reprint Venous thrombosis in patients with high-grade glioma
    Sophie Taillibert
    aNeurologie Department Pitié Salpétrière Hospital, Paris VI Pierre and Marie Curie University, Assistance Publique des Hôpitaux de Paris Paris bNeuro oncology Unit, Neurooncology Department, Nancy University Hospital, Central Hospital and CRAN UMR 7039 CNRS, SBS BEAM Department, Nancy University, Vandœuvre lès Nancy cNeuro oncology Department, University Hospital dMedical Oncology Department, Oscar Lambret Center, Lille eINSERM U1192, PRISM Laboratory, Lille University, Villeneuve d Ascq, laboratoire Prism, France
    Curr Opin Oncol 27:516-21. 2015
    ..VTE is associated with worsened survival in these patients. At present, the main challenge when prescribing anticoagulants in HGG patients is to address the risk of intracranial hemorrhage and provide the optimal treatment...
  19. pmc Leptomeningeal metastasis: a Response Assessment in Neuro-Oncology critical review of endpoints and response criteria of published randomized clinical trials
    Marc Chamberlain
    Department of Neurology, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington M C Department of Neuroscience, Division of Neuro Oncology, University Hospital, Torino, Italy R S, R R Department of Neurology, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois J R Department of Neuro Oncology, Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Amsterdam, Netherlands D B, W B Departments of Neuro Oncology Mazarin and Radiation Oncology, Pitié Salpêtrière Hospital and University Pierre et Marie Curie, Paris VI, Paris, France S T Austin Brain Tumor Center, Texas Oncology US Oncology Research, Austin, Texas M D G Department of Neuro Oncology, University Hospital, Lille, France E L R Department of Neurology, Oscar Lambret Center, Lille, France E L R Department of Neurology, University of Michigan, Ann Arbor, Michigan L J Department of Neuro oncology, Erasmus MC Daniel den Hoed Cancer Center, Rotterdam, Netherlands M v d B Department of Neurology, Dana Farber Cancer Institute, Massachusetts General Hospital, Boston, Massachusetts P Y W Department of Neurology and Oncology, Mayo Clinic Florida, Jacksonville
    Neuro Oncol 16:1176-85. 2014
    ..To date, response criteria and optimal methods for assessment of outcome have not been standardized in patients with leptomeningeal metastasis (LM)...