Laurent Gros

Summary

Affiliation: Centre d'Ecologie Fonctionnelle et Evolutive
Country: France

Publications

  1. pmc Characterization of two novel forms of the rat sulphonylurea receptor SUR1A2 and SUR1BDelta31
    Laurent Gros
    Institut National de la Santé et de la Recherche Médicale INSERM U376, CHU Arnaud de Villeneuve, 34295 Montpellier Cedex, France
    Br J Pharmacol 137:98-106. 2002
  2. ncbi request reprint Monoclonal antibody-based genetic immunotherapy
    Mireia Pelegrin
    Institute of Molecular Genetics of Montpellier, UMR 5535 IFR122 CNRS 1919, route de Mende 34293 Montpellier Cédex 05, France
    Curr Gene Ther 4:347-56. 2004
  3. pmc Block of Ca(2+)-channels by alpha-endosulphine inhibits insulin release
    Anne Virsolvy
    Institut National de la Santé et de la Recherche Médicale U376, CHU Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier cedex 05, France
    Br J Pharmacol 135:1810-8. 2002
  4. ncbi request reprint Inhibition of ATP-sensitive K+ channels by substituted benzo[c]quinolizinium CFTR activators
    Ann Lise Prost
    CEA, DRDC, Laboratoire de Biophysique Moléculaire et Cellulaire UMR 5090, 17 rue des Martyrs, 38054 Grenoble, France
    Biochem Pharmacol 66:425-30. 2003
  5. ncbi request reprint Counteraction of type 1 diabetic alterations by engineering skeletal muscle to produce insulin: insights from transgenic mice
    Efren Riu
    Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, and Center of Animal Biotechnology and Gene Therapy, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Diabetes 51:704-11. 2002
  6. pmc Efficient mother-to-child transfer of antiretroviral immunity in the context of preclinical monoclonal antibody-based immunotherapy
    Laurent Gros
    Institut de Genetique Moleculaire de Montpellier, UMR 5535 IFR 122, CNRS, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
    J Virol 80:10191-200. 2006
  7. pmc Induction of long-term protective antiviral endogenous immune response by short neutralizing monoclonal antibody treatment
    Laurent Gros
    Mireia Pelegrin Institut de Génétique Moléculaire de Montpellier, UMR 5535 IFR 122, CNRS 1919, Route de Mende 34293, Montpellier Cedex 5, France
    J Virol 79:6272-80. 2005
  8. ncbi request reprint Hijacking of the human alkyl-N-purine-DNA glycosylase by 3,N4-ethenocytosine, a lipid peroxidation-induced DNA adduct
    Laurent Gros
    Groupe Réparation de l ADN, CNRS Unité Mixte de Recherche 8113 LBPA ENS Cachan, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Biol Chem 279:17723-30. 2004
  9. pmc Monoclonal antibody 667 recognizes the variable region A motif of the ecotropic retrovirus CasBrE envelope glycoprotein and inhibits Env binding to the viral receptor
    Hanna Dreja
    Institut de Genetique Moleculaire de Montpellier, CNRS UMR 5535, IFR 122, 34293 Montpellier Cedex 5, France
    J Virol 77:10984-93. 2003
  10. pmc Endogenous cytotoxic T-cell response contributes to the long-term antiretroviral protection induced by a short period of antibody-based immunotherapy of neonatally infected mice
    Laurent Gros
    Institut de Genetique Moleculaire de Montpellier, UMR 5535 IFR 122, CNRS, 1919, route de Mende, 34293 Montpellier Cedex 5, France
    J Virol 82:1339-49. 2008

Collaborators

  • Anne Virsolvy
  • Frances M Ashcroft
  • Mireia Pelegrin
  • D Bataille
  • Hanna Dreja
  • Ann Lise Prost
  • Efren Riu
  • Anna Oates
  • Jean Claude Mani
  • Estanislao Bachrach
  • Michel Vivaudou
  • Frederic Becq
  • Thierry Chardes
  • Sylvie Villard
  • Claude Granier
  • Renaud Derand
  • Marc Piechaczyk
  • Alex Mas
  • Lluis Montoliu
  • Anna Pujol
  • Pedro Otaegui
  • Tura Ferre
  • Fatima Bosch

Detail Information

Publications10

  1. pmc Characterization of two novel forms of the rat sulphonylurea receptor SUR1A2 and SUR1BDelta31
    Laurent Gros
    Institut National de la Santé et de la Recherche Médicale INSERM U376, CHU Arnaud de Villeneuve, 34295 Montpellier Cedex, France
    Br J Pharmacol 137:98-106. 2002
    ..5. These findings confirm that TM16-TM17 of SUR1 are important for high-affinity glibenclamide binding and that their deletion impairs trafficking of the K(ATP) channel to the surface membrane...
  2. ncbi request reprint Monoclonal antibody-based genetic immunotherapy
    Mireia Pelegrin
    Institute of Molecular Genetics of Montpellier, UMR 5535 IFR122 CNRS 1919, route de Mende 34293 Montpellier Cédex 05, France
    Curr Gene Ther 4:347-56. 2004
    ..The present review reports on the recent developments of gene/cell therapies aiming at the in vivo production and systemic delivery of monoclonal antibodies with the final goal of treating severe chronic diseases...
  3. pmc Block of Ca(2+)-channels by alpha-endosulphine inhibits insulin release
    Anne Virsolvy
    Institut National de la Santé et de la Recherche Médicale U376, CHU Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, 34295 Montpellier cedex 05, France
    Br J Pharmacol 135:1810-8. 2002
    ..6. We conclude that alpha-endosulphine is not exclusively an endogenous equivalent for sulphonylureas and not solely a K(ATP) channel regulator...
  4. ncbi request reprint Inhibition of ATP-sensitive K+ channels by substituted benzo[c]quinolizinium CFTR activators
    Ann Lise Prost
    CEA, DRDC, Laboratoire de Biophysique Moléculaire et Cellulaire UMR 5090, 17 rue des Martyrs, 38054 Grenoble, France
    Biochem Pharmacol 66:425-30. 2003
    ..2 subunit. Thus, caution should be exercised when planning to use MPB compounds in cystic fibrosis therapy, specially MPB-91 which could nonetheless find interesting applications as the precursor of a new class of K channel blockers...
  5. ncbi request reprint Counteraction of type 1 diabetic alterations by engineering skeletal muscle to produce insulin: insights from transgenic mice
    Efren Riu
    Department of Biochemistry and Molecular Biology, School of Veterinary Medicine, and Center of Animal Biotechnology and Gene Therapy, Universitat Autonoma de Barcelona, Bellaterra, Spain
    Diabetes 51:704-11. 2002
    ..These results indicate that skeletal muscle may be a key target tissue for insulin production and suggest that muscle cells secreting basal levels of insulin, in conjunction with insulin therapy, may permit tight regulation of glycemia...
  6. pmc Efficient mother-to-child transfer of antiretroviral immunity in the context of preclinical monoclonal antibody-based immunotherapy
    Laurent Gros
    Institut de Genetique Moleculaire de Montpellier, UMR 5535 IFR 122, CNRS, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
    J Virol 80:10191-200. 2006
    ....
  7. pmc Induction of long-term protective antiviral endogenous immune response by short neutralizing monoclonal antibody treatment
    Laurent Gros
    Mireia Pelegrin Institut de Génétique Moléculaire de Montpellier, UMR 5535 IFR 122, CNRS 1919, Route de Mende 34293, Montpellier Cedex 5, France
    J Virol 79:6272-80. 2005
    ....
  8. ncbi request reprint Hijacking of the human alkyl-N-purine-DNA glycosylase by 3,N4-ethenocytosine, a lipid peroxidation-induced DNA adduct
    Laurent Gros
    Groupe Réparation de l ADN, CNRS Unité Mixte de Recherche 8113 LBPA ENS Cachan, Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif Cedex, France
    J Biol Chem 279:17723-30. 2004
    ..The proposed model of ANPG-mediated genotoxicity of epsilonC provides a new insight in the molecular basis of lipid peroxidation-induced cell death and genome instability in cancer...
  9. pmc Monoclonal antibody 667 recognizes the variable region A motif of the ecotropic retrovirus CasBrE envelope glycoprotein and inhibits Env binding to the viral receptor
    Hanna Dreja
    Institut de Genetique Moleculaire de Montpellier, CNRS UMR 5535, IFR 122, 34293 Montpellier Cedex 5, France
    J Virol 77:10984-93. 2003
    ....
  10. pmc Endogenous cytotoxic T-cell response contributes to the long-term antiretroviral protection induced by a short period of antibody-based immunotherapy of neonatally infected mice
    Laurent Gros
    Institut de Genetique Moleculaire de Montpellier, UMR 5535 IFR 122, CNRS, 1919, route de Mende, 34293 Montpellier Cedex 5, France
    J Virol 82:1339-49. 2008
    ....