Jean Pierre Duneau

Summary

Affiliation: Aix-Marseille university CNRS
Location: Marseilles, France
URL: http://lism/JS_files/Page_JS

Publications

  1. ncbi request reprint Detailed description of an alpha helix-->pi bulge transition detected by molecular dynamics simulations of the p185c-erbB2 V659G transmembrane domain
    J P Duneau
    Centre de Biophysique Moleculaire, Orleans, France
    J Biomol Struct Dyn 13:753-69. 1996
  2. ncbi request reprint Molecular modeling of c-erbB2 receptor dimerization: coiled-coil structure of wild and oncogenic transmembrane domains--stabilization by interhelical hydrogen bonds in the oncogenic form
    N Garnier
    Centre de Biophysique Moleculaire, CNRS, Universite d Orleans, France
    Biopolymers 42:157-68. 1997
  3. ncbi request reprint Insight into signal transduction: structural alterations in transmembrane helices probed by multi-1 ns molecular dynamics simulations
    J P Duneau
    Centre de Biophysique Moleculaire, CNRS, Orleans, France
    J Biomol Struct Dyn 15:555-72. 1997
  4. ncbi request reprint Time resolved fluorescence properties of phenylalanine in different environments. Comparison with molecular dynamics simulation
    J P Duneau
    CBM UPR 4301 du CNRS, University of Orleans, France
    Biophys Chem 73:109-19. 1998
  5. ncbi request reprint Molecular dynamics simulations of the ErbB-2 transmembrane domain within an explicit membrane environment: comparison with vacuum simulations
    J P Duneau
    Centre de Biophysique Moleculaire, CNRS, Orleans, France
    Biophys Chem 76:35-53. 1999
  6. ncbi request reprint Ptuba: a tool for the visualization of helix surfaces in proteins
    Jaime Arce Lopera
    Laboratoire d Ingénierie des Systèmes Macromoléculaires UPR 9027, Institut de Biologie Structurale et Microbiologie, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    J Mol Graph Model 23:305-15. 2005
  7. ncbi request reprint A dimerization hierarchy in the transmembrane domains of the HER receptor family
    Jean Pierre Duneau
    Unité Propre de Recherche 9027 Laboratoire d Ingénierie des Systèmes Macromoléculaires, Institut de Biologie Structurale et Microbiologie, Centre National de la Recherche Scientifique, Marseille, France
    Biochemistry 46:2010-9. 2007
  8. doi request reprint Dissecting membrane protein architecture: An annotation of structural complexity
    Jaime Arce
    LISM CNRS Aix Marseille Université, Laboratoire d Ingénierie de Systèmes Macromoléculaires UPR9027, Institut de Biologie Structurale et Microbiologie, Marseille cedex 2013402, France
    Biopolymers 91:815-29. 2009
  9. pmc Single-spanning transmembrane domains in cell growth and cell-cell interactions: More than meets the eye?
    Pierre Hubert
    LISM UPR 9027, CNRS Aix Marseille University, Marseille, France
    Cell Adh Migr 4:313-24. 2010

Collaborators

Detail Information

Publications9

  1. ncbi request reprint Detailed description of an alpha helix-->pi bulge transition detected by molecular dynamics simulations of the p185c-erbB2 V659G transmembrane domain
    J P Duneau
    Centre de Biophysique Moleculaire, Orleans, France
    J Biomol Struct Dyn 13:753-69. 1996
    ..Such a deformation closely related to structural motifs described in the literature, induces a change in the distribution of the residues along the helix faces which could modulate the protein activity mediated by a dimerization process...
  2. ncbi request reprint Molecular modeling of c-erbB2 receptor dimerization: coiled-coil structure of wild and oncogenic transmembrane domains--stabilization by interhelical hydrogen bonds in the oncogenic form
    N Garnier
    Centre de Biophysique Moleculaire, CNRS, Universite d Orleans, France
    Biopolymers 42:157-68. 1997
    ..Structural and energetical characterization of the models are presented...
  3. ncbi request reprint Insight into signal transduction: structural alterations in transmembrane helices probed by multi-1 ns molecular dynamics simulations
    J P Duneau
    Centre de Biophysique Moleculaire, CNRS, Orleans, France
    J Biomol Struct Dyn 15:555-72. 1997
    ..These structural alterations are discussed in term of structure-activity relationships for the c-erbB-2 activating mechanism mediated by transmembrane domain dimerization...
  4. ncbi request reprint Time resolved fluorescence properties of phenylalanine in different environments. Comparison with molecular dynamics simulation
    J P Duneau
    CBM UPR 4301 du CNRS, University of Orleans, France
    Biophys Chem 73:109-19. 1998
    ..05 ns). Autocorrelation functions computed from MD simulations corroborate these results...
  5. ncbi request reprint Molecular dynamics simulations of the ErbB-2 transmembrane domain within an explicit membrane environment: comparison with vacuum simulations
    J P Duneau
    Centre de Biophysique Moleculaire, CNRS, Orleans, France
    Biophys Chem 76:35-53. 1999
    ....
  6. ncbi request reprint Ptuba: a tool for the visualization of helix surfaces in proteins
    Jaime Arce Lopera
    Laboratoire d Ingénierie des Systèmes Macromoléculaires UPR 9027, Institut de Biologie Structurale et Microbiologie, 31 Chemin Joseph Aiguier, 13402 Marseille Cedex 20, France
    J Mol Graph Model 23:305-15. 2005
    ..We propose the use of this tool as an aid to the visualization and analysis of transmembrane helix surfaces and properties...
  7. ncbi request reprint A dimerization hierarchy in the transmembrane domains of the HER receptor family
    Jean Pierre Duneau
    Unité Propre de Recherche 9027 Laboratoire d Ingénierie des Systèmes Macromoléculaires, Institut de Biologie Structurale et Microbiologie, Centre National de la Recherche Scientifique, Marseille, France
    Biochemistry 46:2010-9. 2007
    ..The correlation we observe between transmembrane domain and whole receptor interaction hierarchies opens a new perspective, suggesting a role for transmembrane receptor domains in the modulation of receptor signaling...
  8. doi request reprint Dissecting membrane protein architecture: An annotation of structural complexity
    Jaime Arce
    LISM CNRS Aix Marseille Université, Laboratoire d Ingénierie de Systèmes Macromoléculaires UPR9027, Institut de Biologie Structurale et Microbiologie, Marseille cedex 2013402, France
    Biopolymers 91:815-29. 2009
    ..More importantly, the proposed annotation will help to decipher the complex hierarchy of interactions involved in membrane protein architecture...
  9. pmc Single-spanning transmembrane domains in cell growth and cell-cell interactions: More than meets the eye?
    Pierre Hubert
    LISM UPR 9027, CNRS Aix Marseille University, Marseille, France
    Cell Adh Migr 4:313-24. 2010
    ..This review attempts to give an overview of current knowledge about these interactions, from structural data to therapeutic perspectives, focusing on bitopic proteins involved in cell signaling...