Affiliation: Centre d'Ecologie Fonctionnelle et Evolutive
- From Cdc2 to Cdk1: when did the cell cycle kinase join its cyclin partner?Marcel Doree
CRBM, UPR 1086 CNRS, 1919 Route de Mende, 34293 Montpellier Cedex 5, France
J Cell Sci 115:2461-4. 2002..When this fundamental discovery was confirmed in vertebrates and mammalian members of the Cdc2 family were also shown to bind cyclins, Cdc2 became Cdk1, the first cyclin-dependent protein kinase...
- [Triggering cell mitosis in higher eukaryotes]Marcel Doree
CRBM, UPR 1086 CNRS, 1919, route de Mende, 34290 Montpellier, France
Med Sci (Paris) 19:299-307. 2003..This review discusses possible pathways and mechanisms involved in triggering onset of mitosis in such cells, including inhibitory checkpoint mechanisms that detect defects in structural organisation of the cell...
- Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1Marion Peter
Centre de Recherches de Biochimie Macromoleculaire, CNRS UPR 1086, 1919 Route de Mende, F 34293 Montpellier cedex 5, France
EMBO Rep 3:551-6. 2002..We demonstrate that cyclin B1 phosphorylation has another essential function in vivo: it is required for cdc25c and MPF activation, which does not require nuclear accumulation of cyclin B1, and occurs in the cytoplasm...
- A new role for Mos in Xenopus oocyte maturation: targeting Myt1 independently of MAPKMarion Peter
CNRS CRBM, 1919 Route de Mende, 34293 Montpellier Cedex 05, France
Development 129:2129-39. 2002..We propose that Mos is involved, not only in the MAPK cascade pathway, but also in a mechanism that directly activates MPF in Xenopus oocytes...