Marc Antoine Custaud

Summary

Affiliation: Centre Hospitalier Universitaire
Country: France

Publications

  1. pmc Contribution of social isolation, restraint, and hindlimb unloading to changes in hemodynamic parameters and motion activity in rats
    Darya Tsvirkun
    UMR CNRS 6214 INSERM 1083, Faculté de Médecine d Angers, Universite d Angers, Angers, France
    PLoS ONE 7:e39923. 2012
  2. ncbi request reprint [Regulation of blood volume during weightlessness simulation of long duration]
    Marc Antoine Custaud
    Laboratoire de Physiologie, Unite Mixte de Recherche, Centre national de la recherche scientifique UMR CNRS 6188, Rue Haute de Reculee, 49045 Angers cedex 01, France
    Can J Physiol Pharmacol 83:1147-53. 2005
  3. doi request reprint Involvement of angiotensin II in the remodeling induced by a chronic decrease in blood flow in rat mesenteric resistance arteries
    Celine Baron-Menguy
    INSERM U771, Angers, France
    Hypertens Res 33:857-66. 2010
  4. doi request reprint Low-magnitude whole body vibration with resistive exercise as a countermeasure against cardiovascular deconditioning after 60 days of head-down bed rest
    Mickael Coupé
    UMR CNRS 6214 Inserm 771, Faculté de Médecine d Angers, Angers, France
    Am J Physiol Regul Integr Comp Physiol 301:R1748-54. 2011
  5. pmc AGEs breaking and antioxidant treatment improves endothelium-dependent dilation without effect on flow-mediated remodeling of resistance arteries in old Zucker diabetic rats
    Mohamed L Freidja
    INSERM U1083, Angers, France
    Cardiovasc Diabetol 13:55. 2014
  6. doi request reprint Skin vascular resistance in the standing position increases significantly after 7 days of dry immersion
    Nastassia M Navasiolava
    CNRS UMR INSERM U, Faculté de Médecine d Angers, France
    Auton Neurosci 160:64-8. 2011
  7. ncbi request reprint Noisy fluctuation of heart rate indicates cardiovascular system instability
    Jacques Olivier Fortrat
    Faculté de Médecine d Angers, UMR CNRS 6214 Inserm 1083 Biologie Neurovasculaire et Mitochondriale Intégrée, Rue Haute de Reculee, 49045 Angers Cedex, France
    Eur J Appl Physiol 113:2253-61. 2013
  8. ncbi request reprint Blood volume measurement: The comparison of pulse dye densitometry and Dill and Costill's methods
    Eric Belin de Chantemele
    Laboratoire de Physiologie, UMR CNRS 6188, Faculté de Médecine d Angers, Rue Haute de Reculee, 49045 Angers Cedex, France
    Life Sci 78:1564-9. 2006
  9. ncbi request reprint WISE 2005: chronic bed rest impairs microcirculatory endothelium in women
    Claire Demiot
    CHU d Angers, Centre de Recherche Clinique, Angers, France
    Am J Physiol Heart Circ Physiol 293:H3159-64. 2007
  10. ncbi request reprint Increased hydration alone does not improve orthostatic tolerance in patients with neurocardiogenic syncope
    Elisabeth Bellard
    Laboratoire de Physiology, UMR CNRS 6214 Inserm 771, Faculté de Médecine d Angers rue Haute de Reculée, Angers, France
    Clin Auton Res 17:99-105. 2007

Collaborators

  • Claude Gharib
  • Jacques Olivier Fortrat
  • Laurent Loufrani
  • Daniel Henrion
  • Nastassia M Navasiolava
  • Kaname Hirayanagi
  • Satoshi Iwase
  • Guillemette Gauquelin-Koch
  • Eric Belin de Chantemele
  • Anne Laure Guihot
  • Emilie Vessieres
  • Bertrand Toutain
  • Celine Baron-Menguy
  • Maud Cousin
  • Claire Demiot
  • Mohamed L Freidja
  • Darya Tsvirkun
  • Mickael Coupé
  • Jean François Subra
  • Odile Dumont
  • Irina Larina
  • Philippe Arbeille
  • Elisabeth Bellard
  • Heather Edgell
  • Monique Duvareille
  • Natacha Pellet
  • Guido Ferretti
  • Christophe Chiquet
  • Celine Fassot
  • Olga Vinogradova
  • Aurélie Mieuset
  • Florian Garo
  • Jennifer Bourreau
  • Yongzhi Z Li
  • Yanqiang Q Bai
  • Yinghui H Li
  • Ming Yuan
  • Thibaud Levrard
  • Shizhong Z Jiang
  • J Kevin Shoemaker
  • Richard Hughson
  • Danielle K Greaves
  • Phillipe Arbeille
  • Kathryn A Zuj
  • John Greenleaf
  • Georges Leftheriotis
  • Pascaline Kerbeci
  • Florence Sabatier
  • Francoise Dignat-George
  • Jacques Victor
  • Richard L Hughson
  • Francis Louisy
  • Ludovic Pascaud
  • Stephane Blanc
  • Arnaud Capri
  • Catherine Millet
  • Philippe Denis
  • Anne Pavy Le Traon

Detail Information

Publications19

  1. pmc Contribution of social isolation, restraint, and hindlimb unloading to changes in hemodynamic parameters and motion activity in rats
    Darya Tsvirkun
    UMR CNRS 6214 INSERM 1083, Faculté de Médecine d Angers, Universite d Angers, Angers, France
    PLoS ONE 7:e39923. 2012
    ....
  2. ncbi request reprint [Regulation of blood volume during weightlessness simulation of long duration]
    Marc Antoine Custaud
    Laboratoire de Physiologie, Unite Mixte de Recherche, Centre national de la recherche scientifique UMR CNRS 6188, Rue Haute de Reculee, 49045 Angers cedex 01, France
    Can J Physiol Pharmacol 83:1147-53. 2005
    ..It suggests that in man, the main regulatory factor for ADH secretion is osmolality, when PV is modestly and progressively decreased without arterial pressure modification, which was the case in the present protocol...
  3. doi request reprint Involvement of angiotensin II in the remodeling induced by a chronic decrease in blood flow in rat mesenteric resistance arteries
    Celine Baron-Menguy
    INSERM U771, Angers, France
    Hypertens Res 33:857-66. 2010
    ..These findings might be of importance in the treatment of vascular disorders...
  4. doi request reprint Low-magnitude whole body vibration with resistive exercise as a countermeasure against cardiovascular deconditioning after 60 days of head-down bed rest
    Mickael Coupé
    UMR CNRS 6214 Inserm 771, Faculté de Médecine d Angers, Angers, France
    Am J Physiol Regul Integr Comp Physiol 301:R1748-54. 2011
    ..The underlying mechanisms remain hypothetical but might involve cutaneous and muscular mechanoreceptors...
  5. pmc AGEs breaking and antioxidant treatment improves endothelium-dependent dilation without effect on flow-mediated remodeling of resistance arteries in old Zucker diabetic rats
    Mohamed L Freidja
    INSERM U1083, Angers, France
    Cardiovasc Diabetol 13:55. 2014
    ..As type 2 diabetes occurs preferentially in older subjects we investigated flow-mediated remodeling and the effect of the AGEs breaker ALT-711 associated or not to the antioxidant TEMPOL in one-year old lean (LZ) and ZDF rats...
  6. doi request reprint Skin vascular resistance in the standing position increases significantly after 7 days of dry immersion
    Nastassia M Navasiolava
    CNRS UMR INSERM U, Faculté de Médecine d Angers, France
    Auton Neurosci 160:64-8. 2011
    ....
  7. ncbi request reprint Noisy fluctuation of heart rate indicates cardiovascular system instability
    Jacques Olivier Fortrat
    Faculté de Médecine d Angers, UMR CNRS 6214 Inserm 1083 Biologie Neurovasculaire et Mitochondriale Intégrée, Rue Haute de Reculee, 49045 Angers Cedex, France
    Eur J Appl Physiol 113:2253-61. 2013
    ..It also indicates cardiovascular instability because it does not disappear in upright patients before vasovagal syncope, a transient failure of cardiovascular regulation...
  8. ncbi request reprint Blood volume measurement: The comparison of pulse dye densitometry and Dill and Costill's methods
    Eric Belin de Chantemele
    Laboratoire de Physiologie, UMR CNRS 6188, Faculté de Médecine d Angers, Rue Haute de Reculee, 49045 Angers Cedex, France
    Life Sci 78:1564-9. 2006
    ..27). The DDG gives a good repeatability, not affected by the microgravity exposure. Thanks to its capacity to measure accurately the BV within 7-10 min, this device presents major advantages for clinical use and research purpose...
  9. ncbi request reprint WISE 2005: chronic bed rest impairs microcirculatory endothelium in women
    Claire Demiot
    CHU d Angers, Centre de Recherche Clinique, Angers, France
    Am J Physiol Heart Circ Physiol 293:H3159-64. 2007
    ..We therefore conclude that the endothelium should be a target for countermeasures during periods of prolonged deconditioning...
  10. ncbi request reprint Increased hydration alone does not improve orthostatic tolerance in patients with neurocardiogenic syncope
    Elisabeth Bellard
    Laboratoire de Physiology, UMR CNRS 6214 Inserm 771, Faculté de Médecine d Angers rue Haute de Reculée, Angers, France
    Clin Auton Res 17:99-105. 2007
    ..Moreover in this patient group there was no association between a low plasma volume and a reduced tolerance to orthostatic stress...
  11. doi request reprint Role of angiotensin II in the remodeling induced by a chronic increase in flow in rat mesenteric resistance arteries
    Maud Cousin
    Centre National de la Recherche Scientifique Unité Mixte de Recherche 6214, Institut National de la Santé et de la Recherche Médicale U771, Universite d Angers, Angers, France
    Hypertension 55:109-15. 2010
    ..Thus, a chronic rise in blood flow in resistance arteries induces a diameter enlargement involving NO and superoxide, whereas hypertrophy was associated with extracellular signal-regulated kinase 1/2 activation by angiotensin II...
  12. ncbi request reprint Does resistance exercise prevent body fluid changes after a 90-day bed rest?
    Eric Belin de Chantemele
    Laboratoire de Physiologie de l Environnement, Faculte de Medecine, Lyon Grange Blanche, 8 avenue Rockefeller, 69373, Lyon, Cedex 08, France
    Eur J Appl Physiol 92:555-64. 2004
    ..g. LBNP) might be a better countermeasure...
  13. ncbi request reprint Hormonal changes during 17 days of head-down bed-rest
    Marc Antoine Custaud
    Laboratoire de Physiologie de l Environnement GIP exercice, Faculte de Medecine Lyon Grange Blanche, 8 avenue Rockefeller, F 69373 Lyon Cedex 08, France
    Life Sci 72:1001-14. 2003
    ..A decrease during the night was noted for normetadrenaline urinary derivates, but only during the HDBR...
  14. ncbi request reprint Effect of centrifuge-induced artificial gravity and ergometric exercise on cardiovascular deconditioning, myatrophy, and osteoporosis induced by a -6 degrees head-down bedrest
    Satoshi Iwase
    Dept Physiol II, Aichi Med Univ, Aichi, Japan
    J Gravit Physiol 11:P243-4. 2004
    ..The combination of high/low G-load with low/high intensity exercise will determine the optimal protocol for prevention of cardiovascular deconditioning, myatrophy, and osteoporosis...
  15. ncbi request reprint WISE-2005: adrenergic responses of women following 56-days, 6 degrees head-down bed rest with or without exercise countermeasures
    Heather Edgell
    Faculty of Applied Health Sciences, Rm 3116, Burt Matthews Hall, Univ of Waterloo, Waterloo, ON, Canada, N2L 3G1
    Am J Physiol Regul Integr Comp Physiol 293:R2343-52. 2007
    ..The reduced peripheral vascular resistance after HDBR might help to explain orthostatic intolerance in women. Exercise was an effective countermeasure to the HDBR effects...
  16. pmc Calf venous volume during stand-test after a 90-day bed-rest study with or without exercise countermeasure
    Eric Belin de Chantemele
    Laboratoire de Physiologie de l Environnement, Faculte de Medecine Lyon Grange Blanche, Lyon, France
    J Physiol 561:611-22. 2004
    ..It also showed that a combined eccentric-concentric resistance exercise countermeasure had no effects on either post-HDT OI or on the venous parameters related to it...
  17. ncbi request reprint Changes in intraocular pressure during prolonged (7-day) head-down tilt bedrest
    Christophe Chiquet
    Department of Ophthalmology, Edouard Herriot Hospital, Claude Bernard Lyon 1 University, Lyon, France
    J Glaucoma 12:204-8. 2003
    ..To determine the change in intraocular pressure (IOP) due to postural changes in young healthy volunteers...
  18. ncbi request reprint Orthostatic tolerance and spontaneous baroreflex sensitivity in men versus women after 7 days of head-down bed rest
    Marc Antoine Custaud
    Laboratoire de Physiologie de l Environnement, Lyon, France
    Auton Neurosci 100:66-76. 2002
    ..The time frequency method we developed to study changes in spontaneous baroreflex might be applied to the analysis of LBNP tests...
  19. ncbi request reprint [Orthostatic tolerance after spaceflight or simulated weightlessness by head-down bed-rest]
    Claude Gharib
    Universite Claude Bernard Lyon 1, Faculte de Medecine Lyon Grange Blanche, Laboratoire de Physiologie de l Environnement, 8 avenue Rockefeller 69373 Lyon
    Bull Acad Natl Med 186:733-46; discussion 747-9. 2002
    ..However the mechanisms are different even if they have a common postural orthostatic tachycardia syndrome (POTS). The spaceflight duration was not determinant and we have no indice to predict OI which was one of the aims of the study...