Research Topics
| Jérôme BoursierSummaryAffiliation: Centre Hospitalier Universitaire Country: France Publications
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Detail Information
Publications
Liver fibrosis in patients with non-alcoholic fatty liver disease: diagnostic options in clinical practiceJérôme Boursier
University Hospital, Liver Gastroenterology department, 49933 Angers cedex 09, France 33 2 41 35 34 10 33 2 41 35 41 19
Expert Opin Med Diagn 6:381-94. 2012..They represent an exciting research field as further studies are required to definitively validate their diagnostic and prognostic utility...
Determination of reliability criteria for liver stiffness evaluation by transient elastographyJérôme Boursier
Liver Gastroenterology department, University Hospital, and HIFIH Laboratory, UPRES 3859, SFR 4038, LUNAM University, Angers, France
Hepatology 57:1182-91. 2013..LSE reliability depends on IQR/M according to liver stiffness median level, defining thus three reliability categories: very reliable, reliable, and poorly reliable LSE. (HEPATOLOGY 2013)...
Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasiveJérôme Boursier
Department of Hepatogastroenterology, University Hospital, Angers, France
Hepatology 55:58-67. 2012....
Liver fibrogenesis and genetic factorsJérôme Boursier
Service d Hepato Gastroenterologie, Centre Hospitalier Universitaire d Angers et Laboratoire HIFIH, UPRES 3859, IFR 132, 4 rue Larrey 49933 Angers Cedex 9, France
Clin Res Hepatol Gastroenterol 35:S3-9. 2011..Moreover, functional analyses of these genes may provide new insights into the pathophysiology of liver fibrogenesis...
A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis CJérôme Boursier
Service d Hepato Gastroenterologie, CHU, Angers, France
Am J Gastroenterol 106:1255-63. 2011..Our aim was to develop a new and more accurate fibrosis stage classification by using new scores combining non-invasive fibrosis tests...
Acoustic radiation force impulse: a new ultrasonographic technology for the widespread noninvasive diagnosis of liver fibrosisJérôme Boursier
Departments of aHepato gastroenterology bRadiology cBiochemistry, CHU dHIFIH laboratory, Angers University, PRES UNAM, Angers, France
Eur J Gastroenterol Hepatol 22:1074-84. 2010..We aimed to evaluate accuracy, feasibility, reproducibility, and training effect of ARFI for liver fibrosis evaluation...
Optimization and robustness of blood tests for liver fibrosis and cirrhosisPaul Cales
Service d Hepato Gastroenterologie, CHU, Angers, France
Clin Biochem 43:1315-22. 2010..To optimize the performance and feasibility of fibrosis blood tests and evaluate their robustness...
Diagnosis of different liver fibrosis characteristics by blood tests in non-alcoholic fatty liver diseasePaul Cales
Service d Hepato Gastroenterologie, CHU, Angers, France
Liver Int 30:1346-54. 2010..Our aim was to develop an accurate, non-invasive, blood-test-based method for identifying the main characteristics of liver fibrosis in non-alcoholic fatty liver disease (NAFLD)...
Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis CPaul Cales
Service d Hépato gastroentérologie et laboratoire HIFIH, IFR 132, CHU, Angers, France
Liver Int 28:1352-62. 2008..The reliable diagnosis rate of diagnostic tests is provided by their intervals with acceptable accuracy (e.g. >/=90%) where a liver biopsy can be avoided...
Steatosis degree, measured by morphometry, is linked to other liver lesions and metabolic syndrome components in patients with NAFLDJérôme Boursier
Department of Hepato Gastroenterology, University Hospital, Angers, France
Eur J Gastroenterol Hepatol 23:974-81. 2011..We carried out morphometric measurements of steatosis to evaluate relationships between steatosis degree and other liver lesions or metabolic syndrome components in nonalcoholic fatty liver disease (NAFLD)...
Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis CJérôme Boursier
Liver Gastroenterology department, University Hospital, Angers, France
BMC Gastroenterol 11:132. 2011..The secondary aim was to validate these accuracies in independent populations...
Reproducibility of liver stiffness measurement by ultrasonographic elastometryJérôme Boursier
University of Angers, IFR 132, HIFIH Laboratory, UPRES 3859, Angers, France
Clin Gastroenterol Hepatol 6:1263-9. 2008..Fibroscan is a noninvasive device that assesses liver fibrosis by liver stiffness evaluation (LSE) with ultrasonographic elastometry. We evaluated LSE reproducibility and its influencing factors...
The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosisJérôme Boursier
HIFIH Laboratory, IFR 132, University, PRES UNAM, Angers, France
Liver Int 29:1507-15. 2009..We evaluated whether their synchronous combination in new scores could improve the diagnostic accuracy and reduce liver biopsy requirement in algorithm...
Diagnostic accuracy, reproducibility and robustness of fibrosis blood tests in chronic hepatitis C: a meta-analysis with individual dataVincent Leroy
Clinique d Hépato gastroentérologie, Pôle Digestif DUNE, CHU, Grenoble, France
Clin Biochem 41:1368-76. 2008..To evaluate the diagnostic accuracy of liver fibrosis tests and its influencing factors in a meta-analysis with individual data...
Comparison of blood tests for liver fibrosis specific or not to NAFLDPaul Cales
Service d Hepato Gastroenterologie, CHU, 49933 Angers cedex 09, France
J Hepatol 50:165-73. 2009..To compare blood tests of liver fibrosis specific for NAFLD: the FibroMeter NAFLD and the NAFLD fibrosis score (NFSA) with a non-specific test, APRI...
[Bleeding from rectal varices in a patient with severe decompensated cirrhosis: success of endoscopic band ligation. A case report and review of the literature]Jérôme Boursier
Service d Hepato Gastroenterologie, Centre Hospitalier Universitaire, Angers
Gastroenterol Clin Biol 30:783-5. 2006..We report the case of a patient with severe decompensated cirrhosis and bleeding rectal varices who was successfully treated by endoscopic band ligation...
Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis CJérôme Boursier
Hepatogastroenterology Department, CHU, Angers, France
Eur J Gastroenterol Hepatol 21:28-38. 2009..Blood tests are usually designed to identify significant fibrosis. We evaluated their diagnostic accuracy, and how to increase it, for the clinically important targets of severe fibrosis and cirrhosis...
Assessment of new hyaluronic acid assays and their impact on FibroMeter scoresPascal Veillon
Virology Department, Angers University Hospital, Angers, France
Clin Chim Acta 412:347-52. 2011..We compared three hyaluronic acid (HA) assays and analyzed the impact of their variations on FibroMeter scores...
Portosystemic collateral vessels in liver cirrhosis: a three-dimensional MDCT pictorial reviewElie Moubarak
Department of Radiology, Angers University Hospital, Angers, France
Abdom Imaging 37:746-66. 2012..Portosystemic collateral vessels (PSCV) are a consequence of the portal hypertension that occurs in chronic liver diseases. Their prognosis is strongly marked by the risk of digestive hemorrhage and hepatic encephalopathy...
[Characteristics and interpretation of blood tests for liver fibrosis]Jérôme Boursier
Laboratoire HIFIH, UPRES EA 3859, IFR 132, Universite, Service d Hepato Gastroenterologie, CHU, Angers Cedex 9
Gastroenterol Clin Biol 31:511-23; quiz 500, 531-2. 2007
Learning curve and interobserver reproducibility evaluation of liver stiffness measurement by transient elastographyJérôme Boursier
University of Angers, IFR 132, HIFIH Laboratory UPRES 3859, IFR 132, Angers, F 49035 France
Eur J Gastroenterol Hepatol 20:693-701. 2008..Fibroscan allows liver stiffness examination (LSE) that is well correlated with fibrosis stages. Our main objective was to evaluate LSE learning curve...
Noninvasive liver steatosis quantification using MRI techniques combined with blood markersElodie Cesbron-Métivier
Service des maladies du foie et de l appareil digestif, Angers, France
Eur J Gastroenterol Hepatol 22:973-82. 2010..To evaluate the accuracy of different techniques of MRI steatosis quantification, based on histological grading and quantification of liver steatosis...
Transarterial chemoembolisation: effect of selectivity on tolerance, tumour response and survivalAntoine Bouvier
Department of Radiology, CHU Angers, Angers, France
Eur Radiol 21:1719-26. 2011..To compare selective and non-selective TACE techniques in the treatment of HCC with a special emphasis on clinical and liver tolerance, tumour response and survival...
[Infection and variceal bleeding in cirrhosis]Jérôme Boursier
Laboratoire HIFIH, UPRES EA 3859, IFR 132, Universite, Angers
Gastroenterol Clin Biol 31:27-38. 2007..In patients with cirrhosis and variceal bleeding, antibiotic-prophylaxis decreases bacterial infection and the incidence of early rebleeding, and, more important, significantly decreases the death rate in these patients...
