Jérôme Boursier

Summary

Affiliation: Centre Hospitalier Universitaire
Country: France

Publications

  1. doi request reprint A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C
    Jérôme Boursier
    Service d Hepato Gastroenterologie, CHU, Angers, France
    Am J Gastroenterol 106:1255-63. 2011
  2. pmc Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C
    Jérôme Boursier
    Liver Gastroenterology department, University Hospital, Angers, France
    BMC Gastroenterol 11:132. 2011
  3. doi request reprint Precise evaluation of liver histology by computerized morphometry shows that steatosis influences liver stiffness measured by transient elastography in chronic hepatitis C
    Jérôme Boursier
    Liver Gastroenterology department, University Hospital, Angers, France
    J Gastroenterol 49:527-37. 2014
  4. doi request reprint Liver fibrosis in patients with non-alcoholic fatty liver disease: diagnostic options in clinical practice
    Jérôme Boursier
    University Hospital, Liver Gastroenterology department, 49933 Angers cedex 09, France 33 2 41 35 34 10 33 2 41 35 41 19
    Expert Opin Med Diagn 6:381-94. 2012
  5. doi request reprint Determination of reliability criteria for liver stiffness evaluation by transient elastography
    Jérôme Boursier
    Liver Gastroenterology department, University Hospital, and HIFIH Laboratory, UPRES 3859, SFR 4038, LUNAM University, Angers, France
    Hepatology 57:1182-91. 2013
  6. doi request reprint Liver fibrogenesis and genetic factors
    Jérôme Boursier
    Service d Hepato Gastroenterologie, Centre Hospitalier Universitaire d Angers et Laboratoire HIFIH, UPRES 3859, IFR 132, 4 rue Larrey 49933 Angers Cedex 9, France
    Clin Res Hepatol Gastroenterol 35:S3-9. 2011
  7. doi request reprint Acoustic radiation force impulse: a new ultrasonographic technology for the widespread noninvasive diagnosis of liver fibrosis
    Jérôme Boursier
    Departments of aHepato gastroenterology bRadiology cBiochemistry, CHU dHIFIH laboratory, Angers University, PRES UNAM, Angers, France
    Eur J Gastroenterol Hepatol 22:1074-84. 2010
  8. doi request reprint Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive
    Jérôme Boursier
    Department of Hepatogastroenterology, University Hospital, Angers, France
    Hepatology 55:58-67. 2012
  9. doi request reprint Diagnosis of different liver fibrosis characteristics by blood tests in non-alcoholic fatty liver disease
    Paul Cales
    Service d Hepato Gastroenterologie, CHU, Angers, France
    Liver Int 30:1346-54. 2010
  10. doi request reprint Optimization and robustness of blood tests for liver fibrosis and cirrhosis
    Paul Cales
    Service d Hepato Gastroenterologie, CHU, Angers, France
    Clin Biochem 43:1315-22. 2010

Collaborators

Detail Information

Publications28

  1. doi request reprint A new combination of blood test and fibroscan for accurate non-invasive diagnosis of liver fibrosis stages in chronic hepatitis C
    Jérôme Boursier
    Service d Hepato Gastroenterologie, CHU, Angers, France
    Am J Gastroenterol 106:1255-63. 2011
    ..Our aim was to develop a new and more accurate fibrosis stage classification by using new scores combining non-invasive fibrosis tests...
  2. pmc Comparison of accuracy of fibrosis degree classifications by liver biopsy and non-invasive tests in chronic hepatitis C
    Jérôme Boursier
    Liver Gastroenterology department, University Hospital, Angers, France
    BMC Gastroenterol 11:132. 2011
    ..The secondary aim was to validate these accuracies in independent populations...
  3. doi request reprint Precise evaluation of liver histology by computerized morphometry shows that steatosis influences liver stiffness measured by transient elastography in chronic hepatitis C
    Jérôme Boursier
    Liver Gastroenterology department, University Hospital, Angers, France
    J Gastroenterol 49:527-37. 2014
    ..We aimed to precisely determine the influence of steatosis on LSE by using quantitative and precise morphometric measurements of liver histology...
  4. doi request reprint Liver fibrosis in patients with non-alcoholic fatty liver disease: diagnostic options in clinical practice
    Jérôme Boursier
    University Hospital, Liver Gastroenterology department, 49933 Angers cedex 09, France 33 2 41 35 34 10 33 2 41 35 41 19
    Expert Opin Med Diagn 6:381-94. 2012
    ..They represent an exciting research field as further studies are required to definitively validate their diagnostic and prognostic utility...
  5. doi request reprint Determination of reliability criteria for liver stiffness evaluation by transient elastography
    Jérôme Boursier
    Liver Gastroenterology department, University Hospital, and HIFIH Laboratory, UPRES 3859, SFR 4038, LUNAM University, Angers, France
    Hepatology 57:1182-91. 2013
    ..LSE reliability depends on IQR/M according to liver stiffness median level, defining thus three reliability categories: very reliable, reliable, and poorly reliable LSE. (HEPATOLOGY 2013)...
  6. doi request reprint Liver fibrogenesis and genetic factors
    Jérôme Boursier
    Service d Hepato Gastroenterologie, Centre Hospitalier Universitaire d Angers et Laboratoire HIFIH, UPRES 3859, IFR 132, 4 rue Larrey 49933 Angers Cedex 9, France
    Clin Res Hepatol Gastroenterol 35:S3-9. 2011
    ..Moreover, functional analyses of these genes may provide new insights into the pathophysiology of liver fibrogenesis...
  7. doi request reprint Acoustic radiation force impulse: a new ultrasonographic technology for the widespread noninvasive diagnosis of liver fibrosis
    Jérôme Boursier
    Departments of aHepato gastroenterology bRadiology cBiochemistry, CHU dHIFIH laboratory, Angers University, PRES UNAM, Angers, France
    Eur J Gastroenterol Hepatol 22:1074-84. 2010
    ..We aimed to evaluate accuracy, feasibility, reproducibility, and training effect of ARFI for liver fibrosis evaluation...
  8. doi request reprint Comparison of eight diagnostic algorithms for liver fibrosis in hepatitis C: new algorithms are more precise and entirely noninvasive
    Jérôme Boursier
    Department of Hepatogastroenterology, University Hospital, Angers, France
    Hepatology 55:58-67. 2012
    ..8% versus 34.6% or 24.6%, respectively, P < 10(-3) ). The diagnostic accuracy of the FM+FS classification (86.7%) was not significantly different from those of successive SAFE or BA. However, this new classification required no biopsy...
  9. doi request reprint Diagnosis of different liver fibrosis characteristics by blood tests in non-alcoholic fatty liver disease
    Paul Cales
    Service d Hepato Gastroenterologie, CHU, Angers, France
    Liver Int 30:1346-54. 2010
    ..Our aim was to develop an accurate, non-invasive, blood-test-based method for identifying the main characteristics of liver fibrosis in non-alcoholic fatty liver disease (NAFLD)...
  10. doi request reprint Optimization and robustness of blood tests for liver fibrosis and cirrhosis
    Paul Cales
    Service d Hepato Gastroenterologie, CHU, Angers, France
    Clin Biochem 43:1315-22. 2010
    ..To optimize the performance and feasibility of fibrosis blood tests and evaluate their robustness...
  11. pmc Evaluating the accuracy and increasing the reliable diagnosis rate of blood tests for liver fibrosis in chronic hepatitis C
    Paul Cales
    Service d Hépato gastroentérologie et laboratoire HIFIH, IFR 132, CHU, Angers, France
    Liver Int 28:1352-62. 2008
    ..The reliable diagnosis rate of diagnostic tests is provided by their intervals with acceptable accuracy (e.g. >/=90%) where a liver biopsy can be avoided...
  12. doi request reprint Steatosis degree, measured by morphometry, is linked to other liver lesions and metabolic syndrome components in patients with NAFLD
    Jérôme Boursier
    Department of Hepato Gastroenterology, University Hospital, Angers, France
    Eur J Gastroenterol Hepatol 23:974-81. 2011
    ..We carried out morphometric measurements of steatosis to evaluate relationships between steatosis degree and other liver lesions or metabolic syndrome components in nonalcoholic fatty liver disease (NAFLD)...
  13. doi request reprint Reproducibility of liver stiffness measurement by ultrasonographic elastometry
    Jérôme Boursier
    University of Angers, IFR 132, HIFIH Laboratory, UPRES 3859, Angers, France
    Clin Gastroenterol Hepatol 6:1263-9. 2008
    ..Fibroscan is a noninvasive device that assesses liver fibrosis by liver stiffness evaluation (LSE) with ultrasonographic elastometry. We evaluated LSE reproducibility and its influencing factors...
  14. ncbi request reprint The combination of a blood test and Fibroscan improves the non-invasive diagnosis of liver fibrosis
    Jérôme Boursier
    HIFIH Laboratory, IFR 132, University, PRES UNAM, Angers, France
    Liver Int 29:1507-15. 2009
    ..We evaluated whether their synchronous combination in new scores could improve the diagnostic accuracy and reduce liver biopsy requirement in algorithm...
  15. doi request reprint Diagnostic accuracy, reproducibility and robustness of fibrosis blood tests in chronic hepatitis C: a meta-analysis with individual data
    Vincent Leroy
    Clinique d Hépato gastroentérologie, Pôle Digestif DUNE, CHU, Grenoble, France
    Clin Biochem 41:1368-76. 2008
    ..To evaluate the diagnostic accuracy of liver fibrosis tests and its influencing factors in a meta-analysis with individual data...
  16. doi request reprint Improved diagnostic accuracy of blood tests for severe fibrosis and cirrhosis in chronic hepatitis C
    Jérôme Boursier
    Hepatogastroenterology Department, CHU, Angers, France
    Eur J Gastroenterol Hepatol 21:28-38. 2009
    ..Blood tests are usually designed to identify significant fibrosis. We evaluated their diagnostic accuracy, and how to increase it, for the clinically important targets of severe fibrosis and cirrhosis...
  17. doi request reprint Comparison of blood tests for liver fibrosis specific or not to NAFLD
    Paul Cales
    Service d Hepato Gastroenterologie, CHU, 49933 Angers cedex 09, France
    J Hepatol 50:165-73. 2009
    ..To compare blood tests of liver fibrosis specific for NAFLD: the FibroMeter NAFLD and the NAFLD fibrosis score (NFSA) with a non-specific test, APRI...
  18. ncbi request reprint Quantification of portal-bridging fibrosis area more accurately reflects fibrosis stage and liver stiffness than whole fibrosis or perisinusoidal fibrosis areas in chronic hepatitis C
    Jeremy Sandrini
    Cellular and Tissue Pathology Department, University Hospital, CHU, Angers, France
    Mod Pathol 27:1035-45. 2014
    ....
  19. doi request reprint Assessment of new hyaluronic acid assays and their impact on FibroMeter scores
    Pascal Veillon
    Virology Department, Angers University Hospital, Angers, France
    Clin Chim Acta 412:347-52. 2011
    ..We compared three hyaluronic acid (HA) assays and analyzed the impact of their variations on FibroMeter scores...
  20. ncbi request reprint Improved fibrosis staging by elastometry and blood test in chronic hepatitis C
    Paul Cales
    Liver Gastroenterology department, CHU Angers, Angers, France HIFIH laboratory, UPRES 3859, SFR 4208, LUNAM University, Angers, France
    Liver Int 34:907-17. 2014
    ..Our secondary objectives were to improve staging precision, by developing a detailed fibrosis classification, and reliability (personalized accuracy) determination...
  21. ncbi request reprint [Bleeding from rectal varices in a patient with severe decompensated cirrhosis: success of endoscopic band ligation. A case report and review of the literature]
    Jérôme Boursier
    Service d Hepato Gastroenterologie, Centre Hospitalier Universitaire, Angers
    Gastroenterol Clin Biol 30:783-5. 2006
    ..We report the case of a patient with severe decompensated cirrhosis and bleeding rectal varices who was successfully treated by endoscopic band ligation...
  22. ncbi request reprint Portosystemic collateral vessels in liver cirrhosis: a three-dimensional MDCT pictorial review
    Elie Moubarak
    Department of Radiology, Angers University Hospital, Angers, France
    Abdom Imaging 37:746-66. 2012
    ..Portosystemic collateral vessels (PSCV) are a consequence of the portal hypertension that occurs in chronic liver diseases. Their prognosis is strongly marked by the risk of digestive hemorrhage and hepatic encephalopathy...
  23. ncbi request reprint [Characteristics and interpretation of blood tests for liver fibrosis]
    Jérôme Boursier
    Laboratoire HIFIH, UPRES EA 3859, IFR 132, Universite, Service d Hepato Gastroenterologie, CHU, Angers Cedex 9
    Gastroenterol Clin Biol 31:511-23; quiz 500, 531-2. 2007
  24. doi request reprint Learning curve and interobserver reproducibility evaluation of liver stiffness measurement by transient elastography
    Jérôme Boursier
    University of Angers, IFR 132, HIFIH Laboratory UPRES 3859, IFR 132, Angers, F 49035 France
    Eur J Gastroenterol Hepatol 20:693-701. 2008
    ..Fibroscan allows liver stiffness examination (LSE) that is well correlated with fibrosis stages. Our main objective was to evaluate LSE learning curve...
  25. ncbi request reprint Noninvasive liver steatosis quantification using MRI techniques combined with blood markers
    Elodie Cesbron-Métivier
    Service des maladies du foie et de l appareil digestif, Angers, France
    Eur J Gastroenterol Hepatol 22:973-82. 2010
    ..To evaluate the accuracy of different techniques of MRI steatosis quantification, based on histological grading and quantification of liver steatosis...
  26. doi request reprint Metastatic hepatocellular carcinoma: when surgery and successive palliative treatments lead to remission
    Charlène Brochard
    Department of Hepato Gastroenterology, University Hospital, Angers, France
    Clin Res Hepatol Gastroenterol 38:e19-22. 2014
    ..This tumor was surgically removed. Twenty-one months after this second surgical procedure, i.e., more than 5.5 years after the initial diagnosis of metastatic HCC, the patient was asymptomatic and tumor free...
  27. doi request reprint Transarterial chemoembolisation: effect of selectivity on tolerance, tumour response and survival
    Antoine Bouvier
    Department of Radiology, CHU Angers, Angers, France
    Eur Radiol 21:1719-26. 2011
    ..To compare selective and non-selective TACE techniques in the treatment of HCC with a special emphasis on clinical and liver tolerance, tumour response and survival...
  28. ncbi request reprint [Infection and variceal bleeding in cirrhosis]
    Jérôme Boursier
    Laboratoire HIFIH, UPRES EA 3859, IFR 132, Universite, Angers
    Gastroenterol Clin Biol 31:27-38. 2007
    ..In patients with cirrhosis and variceal bleeding, antibiotic-prophylaxis decreases bacterial infection and the incidence of early rebleeding, and, more important, significantly decreases the death rate in these patients...