Michele Boisdron-Celle

Summary

Affiliation: Centre Paul Papin
Country: France

Publications

  1. doi [Dihydropyrimidine dehydrogenase deficiency and toxicity to fluoropyrimidine]
    M Boisdron-Celle
    Département de biopathologie du cancer, Centre Regional de Lutte Contre le Cancer Paul Papin, CRCNA Inserm U892, Angers
    Ann Biol Clin (Paris) 68:27-32. 2010
  2. doi [Therapeutic drug monitoring of 5-fluorouracil after its administration in high-dose protocols]
    Michele Boisdron-Celle
    CRLCC Paul Papin, Centre Recherche Cancérologie Nantes Angers, INSERM U892, Angers, France
    Therapie 65:171-6. 2010
  3. pmc Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells
    Agnes Basseville
    Cancer Center Paul Papin, INSERM U892 University of Angers, 2 rue Moll, Angers, F 49033, France
    Mol Cancer 10:80. 2011
  4. pmc Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer
    Patrice Cellier
    Centre Paul Papin, Angers, France
    BMC Cancer 11:98. 2011
  5. ncbi [Detection of dihydropyrimidine dehydrogenase deficiency before treatment by fluoropyrimidines]
    Erick Gamelin
    Département d Oncopharmacologie Pharmacogénétique, INSERM U564, Centre Regional de Lutte Contre le Cancer Paul Papin, 2 rue Moll, 49033 Angers Cedex 9, France
    Therapie 62:99-103. 2007

Detail Information

Publications5

  1. doi [Dihydropyrimidine dehydrogenase deficiency and toxicity to fluoropyrimidine]
    M Boisdron-Celle
    Département de biopathologie du cancer, Centre Regional de Lutte Contre le Cancer Paul Papin, CRCNA Inserm U892, Angers
    Ann Biol Clin (Paris) 68:27-32. 2010
    ..We show that DPD deficiency can be already detected primarily to treatment in practice and this detection could avoid life-threatening fluoropyrimidines toxic-side effects...
  2. doi [Therapeutic drug monitoring of 5-fluorouracil after its administration in high-dose protocols]
    Michele Boisdron-Celle
    CRLCC Paul Papin, Centre Recherche Cancérologie Nantes Angers, INSERM U892, Angers, France
    Therapie 65:171-6. 2010
    ..Real-time fluorouracil monitoring may also help identifying patients with higher than expected exposure, thus providing a basis for intensifying supportive care in these patients...
  3. pmc Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells
    Agnes Basseville
    Cancer Center Paul Papin, INSERM U892 University of Angers, 2 rue Moll, Angers, F 49033, France
    Mol Cancer 10:80. 2011
    ..g. mdr1)...
  4. pmc Phase II study of preoperative radiation plus concurrent daily tegafur-uracil (UFT) with leucovorin for locally advanced rectal cancer
    Patrice Cellier
    Centre Paul Papin, Angers, France
    BMC Cancer 11:98. 2011
    ..We also performed a validated pretherapy assessment of DPD activity and assessed its potential influence on the tolerability of UFT treatment...
  5. ncbi [Detection of dihydropyrimidine dehydrogenase deficiency before treatment by fluoropyrimidines]
    Erick Gamelin
    Département d Oncopharmacologie Pharmacogénétique, INSERM U564, Centre Regional de Lutte Contre le Cancer Paul Papin, 2 rue Moll, 49033 Angers Cedex 9, France
    Therapie 62:99-103. 2007
    ..We must emphasize that it is not merely a genetic result, since the detection of a deficiency most often does not contra-indicate the use of a fluoropyrimidine, but it must be combined with therapeutic advice...