Research Topics
| Cedric AnnweilerSummaryAffiliation: Centre Hospitalier Universitaire Country: France Publications
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Detail Information
Publications
Vitamin D concentration and lateral cerebral ventricle volume in older adultsCedric Annweiler
Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, University Memory Clinic of Angers, UPRES EA 4638, University of Angers, UNAM, Angers, France
Mol Nutr Food Res 57:267-76. 2013..The purpose of this cross-sectional study was to determine whether vitamin D deficiency was associated with greater lateral cerebral ventricle volume in older adults...
Effectiveness of the combination of memantine plus vitamin D on cognition in patients with Alzheimer disease: a pre-post pilot studyCedric Annweiler
Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, Angers, France
Cogn Behav Neurol 25:121-7. 2012..To determine whether treatment with memantine plus vitamin D is more effective than memantine or vitamin D alone in improving cognition among patients with Alzheimer disease (AD)...
Higher vitamin D dietary intake is associated with lower risk of alzheimer's disease: a 7-year follow-upCedric Annweiler
Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, 49933 Angers, France
J Gerontol A Biol Sci Med Sci 67:1205-11. 2012..Our objective was to determine whether the dietary intake of vitamin D was an independent predictor of the onset of dementia within 7 years among women aged 75 years and older...
Vitamin D insufficiency and mild cognitive impairment: cross-sectional associationC Annweiler
Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, Angers Cedex 9, France
Eur J Neurol 19:1023-9. 2012..The association with mild cognitive impairment (MCI) has not yet been explored. Our aim was to examine the association between vitamin D status and MCI status amongst older community-dwellers with subjective memory complaint...
Vitamin D-mentia: randomized clinical trials should be the next stepCedric Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers University Memory Center, UPRES EA 2646, University of Angers, UNAM, Angers, France
Neuroepidemiology 37:249-58. 2011..At this stage, only clinical trials testing vitamin D supplements versus placebo can further determine the impact of vitamin D administration on cognition and AD with higher levels of evidence...
Alzheimer's disease--input of vitamin D with mEmantine assay (AD-IDEA trial): study protocol for a randomized controlled trialCedric Annweiler
Department of Neuroscience, Angers University Hospital, France
Trials 12:230. 2011....
The Five-Times-Sit-to-Stand test, a marker of global cognitive functioning among community-dwelling older womenC Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers, France
J Nutr Health Aging 15:271-6. 2011..To determine whether there was an association between the Five-Times-Sit-to-Stand test (FTSS) and the global cognitive function assessed with Short-Portable-Mental-State-Questionnaire (SPMSQ) among the EPIDOS cohort...
Dietary intake of vitamin D and cognition in older women: a large population-based studyC Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers University Memory Center, UPRES EA 2646, University of Angers, UNAM, Angers, France
Neurology 75:1810-6. 2010..The objective of this cross-sectional study was to determine whether weekly dietary intake of vitamin D could be associated with global cognitive performance among older adults...
Fall prevention and vitamin D in the elderly: an overview of the key role of the non-bone effectsCedric Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers University Memory Center, UPRES EA 2646, University of Angers, UNAM, Angers, France
J Neuroeng Rehabil 7:50. 2010..Vitamin D supplementation should thus be integrated into primary and secondary fall prevention strategies in older adults...
Serum vitamin D concentration and short-term mortality among geriatric inpatients in acute care settingsCedric Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers University Memory Center, University of Angers, UNAM, Angers Cedex 9, Angers, France
Adv Ther 27:245-9. 2010....
Vitamin D and bone fracture mechanisms: what about the non-bone 'D'efense?C Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, France
Int J Clin Pract 64:541-3. 2010..underlined the efficacy of oral supplemental vitamin D, regardless of any additional calcium supplementation, in non-vertebral fractures prevention among more than 42,000 adults aged 65 years and older (2)...
[Vitamin D in the elderly: 5 points to remember]Cedric Annweiler
Département de médecine interne et gériatrie, Centre Hospitalier Universitaire d Angers, France
Geriatr Psychol Neuropsychiatr Vieil 9:259-67. 2011..A daily intake of at least 800-1,000 IU supplemental vitamin D(3) per day is the key...
Vitamin D and cognitive performance in adults: a systematic reviewC Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers, France
Eur J Neurol 16:1083-9. 2009..The inconclusive results of the reviewed studies could be due to methodology, types of the cognitive tasks used and/or the cellular mechanisms of vitamin D...
Association of vitamin D deficiency with cognitive impairment in older women: cross-sectional studyC Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, 49933 Angers Cedex 9, France
Neurology 74:27-32. 2010..The objective of this cross-sectional population-based study was to examine the association between serum 25(OH)D deficiency and cognitive impairment while taking confounders into account...
Cross-sectional association between serum vitamin D concentration and walking speed measured at usual and fast pace among older women: the EPIDOS studyCedric Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers, France
J Bone Miner Res 25:1858-66. 2010..44, p = .003). The findings show a stronger positive association between 25(OH)D concentrations and fast-pace walking speed that is a more sensitive marker of neuromuscular functioning compared with usual-pace walking...
Recurrent falls and dual task-related decrease in walking speed: is there a relationship?Olivier Beauchet
Department of Geriatrics, Angers University Hospitals, Angers, France
J Am Geriatr Soc 56:1265-9. 2008..To determine whether dual task-related changes in walking speed were associated with recurrent falls in frail older adults...
Imagined Timed Up & Go test: a new tool to assess higher-level gait and balance disorders in older adults?Olivier Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospital, UPRES EA 2646, University of Angers, UNAM, France
J Neurol Sci 294:102-6. 2010....
Hypovitaminosis D in geriatric inpatients: a marker of severity of chronic diseasesOlivier Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospital, France
Aging Clin Exp Res 24:188-92. 2012..e., 25OHD ≤25 nmol/L) and, respectively, the number and severity of chronic diseases assessed with the Kaplan- Feinstein index (KFI) among geriatric inpatients...
Profile of French community-dwelling older adults supplemented with vitamin D: findings and lessonsBruno Fantino
Department of Internal Medicine and Geriatrics, Angers University Hospital, France
Adv Ther 28:483-9. 2011..The vast majority of older French adults exhibit some degree of hypovitaminosis D. The objective of this cross-sectional study was to determine the rate and the reasons for vitamin D prescription among older French adult community dwellers...
Association between ambulatory 24-hour blood pressure levels and brain volume reduction: a cross-sectional elderly population-based studySebastien Celle
Service de Physiologie Clinique et de l Exercice, CHU Saint Etienne, Faculté de Médecine Jacque Lisfranc, EA SNA EPIS 4607, UJM, Saint Etienne, PRES de Lyon, France
Hypertension 60:1324-31. 2012..The association of high blood pressure with brain volume reduction may in part explain blood pressure-related cognitive decline leading to dementia...
Gait variability among healthy adults: low and high stride-to-stride variability are both a reflection of gait stabilityOlivier Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospital, University of Angers, UNAM, France
Gerontology 55:702-6. 2009....
Development of a short form of Mini-Mental State Examination for the screening of dementia in older adults with a memory complaint: a case control studyGladys Haubois
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers, France
BMC Geriatr 11:59. 2011..The objective of this study was to determine whether a short form of Mini-Mental State Examination (SMMSE) was as accurate as the Mini-Mental State Examination (MMSE) in screening dementia...
Test-retest reliability of stride time variability while dual tasking in healthy and demented adults with frontotemporal degenerationOlivier Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospital 4 rue larrey, Angers F 49933, France
J Neuroeng Rehabil 8:37. 2011..The objective of this study was to examine immediate test-retest reliability of STV while single and dual tasking in cognitively healthy older individuals (CHI) and in demented patients with frontotemporal degeneration (FTD)...
Vitamin D and ageing: neurological issuesCedric Annweiler
Angers University Memory Center, Angers, France CeAnnweiler chu angers fr
Neuropsychobiology 62:139-50. 2010..Specific actions on the central nervous system (CNS) have been described. The objective of this review was to describe the relationship between vitamin D and the nervous system throughout the different stages of life...
Association between ambulatory 24-hour blood pressure levels and cognitive performance: a cross-sectional elderly population-based studyOliver Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospital, Angers University Memory Center, University of Angers, Angers, France
Rejuvenation Res 13:39-46. 2010....
Gait control: a specific subdomain of executive function?Olivier Beauchet
UPRES EA 2646, University of Angers, UNAM, France
J Neuroeng Rehabil 9:12. 2012..The aim of this study was to examine the association between ESD (i.e., information updating and monitoring) and stride time variability among healthy older adults...
Does change in gait while counting backward predict the occurrence of a first fall in older adults?Olivier Beauchet
Department of Geriatrics, Angers University Hospital, Angers, France
Gerontology 54:217-23. 2008..Dual-task-based assessment tests failed to establish a dependable relationship between dual-task-related gait changes and the risk of falls in the elderly...
Possibility of a new anti-alzheimer's disease pharmaceutical composition combining memantine and vitamin DCedric Annweiler
Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital, Angers, France
Drugs Aging 29:81-91. 2012..gov identifier: NCT01409694). This new pharmaceutical composition may provide an effective solution to the problem of neuronal death and cognitive decline in AD...
Walking speed-related changes in stride time variability: effects of decreased speedOlivier Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospital, UPRES UNAM EA 2646, University of Angers, UNAM, France
J Neuroeng Rehabil 6:32. 2009..We therefore sought to determine the extent to which decrease in self-selected walking speed influenced STV among healthy young adults...
Biology of gait control: vitamin D involvementO Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospitals, 49933 Angers Cedex 9, France
Neurology 76:1617-22. 2011..The objective of this cross-sectional study was to examine the association between stride-to-stride variability of stride time (STV) and serum 25OHD concentration in adults aged 65 years and older...
Decrease in gait variability while counting backward: a marker of "magnet effect"?O Beauchet
Department of Internal Medicine and Geriatrics, Angers University Hospital, UPRES EA 2646, University of Angers, UNAM, 49933 Angers Cedex 9, France
J Neural Transm 117:1171-6. 2010..This behavior was observed only among subjects with the highest gait variability and could be interpreted as an implicit strategy based on the "magnet effect"...
Stops walking when talking: a predictor of falls in older adults?O Beauchet
Department of Geriatrics and Faculty of Medicine, Angers University Hospital and University of Angers, UNAM, France
Eur J Neurol 16:786-95. 2009..Description of health status, standardization of test methodology, increase of sample size and longer follow-up intervals will certainly improve the predictive value of dual-task-based fall risk assessment tests...
Association of angiitis of central nervous system, cerebral amyloid angiopathy, and Alzheimer's disease: report of an autopsy caseCedric Annweiler
Department of Geriatrics and Internal Medicine, Angers University Hospital, Angers Cedex 9, France
Vasc Health Risk Manag 4:1471-4. 2008..We describe here a clinicopathological case associating ACNS, CAA, and AD. We discuss the aetiology of ACNS and its relationship with cerebral deposition of beta A4 amyloid protein (betaA4)...
Extraskeletal effects of vitamin D: facts, uncertainties, and controversiesBéatrice Bouvard
Service de Rhumatologie, CHU d Angers, Universite d Angers, UNAM, 49933 Angers, France
Joint Bone Spine 78:10-6. 2011..This article is a review of the clinical and biological actions of vitamin D including effects on the immune system, auto-immune diseases, infections, cancer, metabolic syndrome, fall risk, cognitive function, and muscle function...
Is there an association between serum 25-hydroxyvitamin D concentration and muscle strength among older women? Results from baseline assessment of the EPIDOS studyC Annweiler
Department of Geriatrics, Angers University Hospital, France
J Nutr Health Aging 13:90-5. 2009....
Suicidal behaviours in affective disorders: a deficit of cognitive inhibition?Stéphane Richard-Devantoy
McGill University, Department of Psychiatry and Douglas Mental Health University Institute, McGill Group for Suicide Studies, Montreal, Quebec
Can J Psychiatry 57:254-62. 2012..Our study aimed to systematically review all published articles that examined the relation between cognitive inhibition deficit and suicidal behaviours (that is, suicide attempt or suicidal ideation) in patients with affective disorders...
Vitamin D and Brain Imaging in the Elderly: Should we Expect Some Lesions Specifically Related to Hypovitaminosis D?Cedric Annweiler
Department of Neuroscience, Division of Geriatric Medicine, Angers University Hospital Angers University Memory Center UPRES EA 2646, University of Angers, UNAM, Angers, France
Open Neuroimag J 6:16-8. 2012..Further imaging studies are required to corroborate this assumption and to determine whether hypovitaminosis D results in degenerative and / or vascular lesions...
Low serum vitamin d concentrations in Alzheimer's disease: a systematic review and meta-analysisCedric Annweiler
Department of Neuroscience, Division of Geriatric Medicine and Memory Clinic, Angers University Hospital, UPRES EA 2646, University of Angers, UNAM, Angers, France Department of Medicine, Division of Geriatric Medicine, Parkwood Hospital, St Joseph s Health Care London, Lawson Health Research Institute, Western University, London, ON, Canada
J Alzheimers Dis 33:659-74. 2013..016). In conclusion, AD cases had lower serum vitamin D concentrations than matched controls. This reinforces the conceptualization of vitamin D as a 'neurosteroid hormone' and as a potential biomarker of AD...
Vitamin D-related changes in physical performance: a systematic reviewC Annweiler
Department of Internal Medicine and Geriatrics, Angers University Hospital, France
J Nutr Health Aging 13:893-8. 2009....
