Genomes and Genes
- Yung P, Stuetzer A, Fischle W, Martinez A, Cavalli G. Histone H3 Serine 28 Is Essential for Efficient Polycomb-Mediated Gene Repression in Drosophila. Cell Rep. 2015;11:1437-45 pubmed publisher..Collectively, our data indicate that the conserved H3S28 residue in metazoans has a role in supporting PRC2 catalysis. ..
- Sati S, Cavalli G. Chromosome conformation capture technologies and their impact in understanding genome function. Chromosoma. 2017;126:33-44 pubmed publisher..We also discuss their inherent limitations and caveats in order to provide a critical view of the power and the limits of this technology. ..
- Entrevan M, Schuettengruber B, Cavalli G. Regulation of Genome Architecture and Function by Polycomb Proteins. Trends Cell Biol. 2016;26:511-525 pubmed publisher..In this review we discuss recent advances in our understanding of how PcG proteins are recruited to chromatin to induce local and global changes in chromosome conformation and regulate their target genes. ..
- Bonev B, Mendelson Cohen N, Szabo Q, Fritsch L, Papadopoulos G, Lubling Y, et al. Multiscale 3D Genome Rewiring during Mouse Neural Development. Cell. 2017;171:557-572.e24 pubmed publisher..Finally, cell type-specific enhancer-promoter contacts are established concomitant to gene expression. This work shows that multiple factors influence the dynamics of chromatin interactions in development. ..