Research Topics
Genomes and Genes
| Frédéric CauseretSummaryAffiliation: Institut Jacques Monod Location: Paris, France URL: http://cvscience.aviesan.fr/cv/566/frederic-causeret Publications
| Collaborators
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Detail Information
Publications
Netrin-1 acts as a survival factor via its receptors UNC5H and DCCF Llambi
Apoptosis Differentiation Laboratory label La Ligue, Molecular and Cellular Genetic Center, CNRS UMR 5534, University of Lyon, 69622 Villeurbanne, France
EMBO J 20:2715-22. 2001..Altogether, these results argue for a role of netrin-1 during the development of the nervous system, not only as a guidance cue but as a survival factor via its receptors DCC and UNC5H...
A novel role for Dbx1-derived Cajal-Retzius cells in early regionalization of the cerebral cortical neuroepitheliumAmélie Griveau
CNRS UMR 7592, Program of Development and Neurobiology, Institut Jacques Monod, Universite Paris Diderot, Paris, France
PLoS Biol 8:e1000440. 2010..Our results strongly suggest that these cells, migrating over long distances and positioned in the postmitotic compartment, signal to ventricular zone progenitors and, thus, function as modulators of early cortical patterning...
Differential roles of Netrin-1 and its receptor DCC in inferior olivary neuron migrationSeverine Marcos
Institut Cochin, Universite Paris Descartes, CNRS UMR 8104, Paris, France INSERM, U567, Paris, France
Mol Cell Neurosci 41:429-39. 2009....
The p21-activated kinase is required for neuronal migration in the cerebral cortexFrédéric Causeret
Department of Cellular and Molecular Neuroscience, Imperial College School of Medicine, London, UK
Cereb Cortex 19:861-75. 2009..Our findings reveal the in vivo importance of temporal and spatial regulation of the Pak1 kinase during key stages of cortical development...
Neurabin-I is phosphorylated by Cdk5: implications for neuronal morphogenesis and cortical migrationFrédéric Causeret
Department of Cellular and Molecular Neuroscience, Imperial College School of Medicine, Charing Cross Campus, London W6 8RP, United Kingdom
Mol Biol Cell 18:4327-42. 2007..Together our findings provide new insight into the signaling pathways responsible for controlled changes of the F-actin cytoskeleton that are required for normal development of the forebrain...
Localized activation of p21-activated kinase controls neuronal polarity and morphologyTom Jacobs
Department of Cellular and Molecular Neuroscience, Division of Neuroscience and Mental Health, Imperial College School of Medicine, Charing Cross Campus, London W6 8RP, United Kingdom
J Neurosci 27:8604-15. 2007..Our data are the first to demonstrate the importance of localized Pak1 kinase activation for neuronal polarization and differentiation...
Differential role of slits in dorsal versus ventral retinal axon guidanceFrédéric Causeret
Division of Neuroscience and Mental Health, Charing Cross Hospital, Imperial College, London W6 8RP, United Kingdom
J Neurosci 26:9839-40. 2006
Distinct priming kinases contribute to differential regulation of collapsin response mediator proteins by glycogen synthase kinase-3 in vivoAdam R Cole
Division of Pathology and Neurosciences, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, Scotland
J Biol Chem 281:16591-8. 2006..This is the first GSK3 substrate found to be regulated in this manner and may explain the hyperphosphorylation of CRMP2 observed in Alzheimer's disease...
Development of precerebellar nuclei: instructive factors and intracellular mediators in neuronal migration, survival and axon pathfindingEvelyne Bloch-Gallego
Institut Cochin, GDPM, INSERM U567, CNRS 8104, Universite Paris V, CHU Cochin, 24 rue du Faubourg Saint Jacques, 75014 Paris, France
Brain Res Brain Res Rev 49:253-66. 2005....
Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1Frédéric Causeret
Institut Cochin, GDPM, INSERM U567, CNRS 8104, Universite Paris V, CHU Cochin, 24 rue du Faubourg Saint Jacques, 75014 Paris, France
Development 131:2841-52. 2004....
Slit antagonizes netrin-1 attractive effects during the migration of inferior olivary neuronsFrédéric Causeret
INSERM U106, Hopital de la Salpetriere, 75013 Paris, France
Dev Biol 246:429-40. 2002..Our results indicate that slit silences the attractive effects of netrin-1 and could participate in the correct ventral positioning of ION, stopping the migration when cell bodies reach the floor-plate...
Dbx1-expressing cells are necessary for the survival of the mammalian anterior neural and craniofacial structuresFrédéric Causeret
CNRS UMR 7592, Institut Jacques Monod, Univ Paris Diderot, Sorbonne Paris Cité, Paris, France
PLoS ONE 6:e19367. 2011..Our results demonstrate that dbx1-expressing cells have a unique function during head development, notably by controlling cell survival in a non cell-autonomous manner...
