C Carnaud

Summary

Country: France

Publications

  1. ncbi Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells
    C Carnaud
    Department of Molecular Biology, Princeton University, NJ 08544, USA
    J Immunol 163:4647-50. 1999
  2. ncbi Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex
    C Carnaud
    Institut National de la Santé et de la Recherche Médicale Unité 25, Hopital Necker, Paris, France
    J Immunol 166:2404-11. 2001
  3. ncbi Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates
    C Mueller
    Department of Pathology, University of Bern, Switzerland
    Diabetes 44:112-7. 1995
  4. ncbi Treatment with neutralizing antibodies specific for IL-1beta prevents cyclophosphamide-induced diabetes in nonobese diabetic mice
    C Cailleau
    INSERM U25, Hopital Necker, Paris, France
    Diabetes 46:937-40. 1997
  5. ncbi NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen
    V Laloux
    , , , Paris, France
    J Immunol 166:3749-56. 2001
  6. ncbi Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes
    A Gonzalez
    Institut de Genetique et de Biologie Moleculaire et Cellulaire CNRS INSERM ULP, Strasbourg, France
    Nat Immunol 2:1117-25. 2001

Collaborators

  • S H Park
  • Werner Held
  • A Bendelac
  • V Laloux
  • A Gonzalez
  • C Cailleau
  • C Benoist
  • L Beaudoin
  • A Lehuen
  • D Jeske
  • D Mathis
  • I Andre-Schmutz
  • C Mueller
  • R Westwood
  • E Ruuth
  • A Diu-Hercend
  • M A Imboden

Detail Information

Publications6

  1. ncbi Cutting edge: Cross-talk between cells of the innate immune system: NKT cells rapidly activate NK cells
    C Carnaud
    Department of Molecular Biology, Princeton University, NJ 08544, USA
    J Immunol 163:4647-50. 1999
    ..They also suggest that the antitumor effects of alpha-GalCer result from the sequential recruitment of distinct innate and adaptive effector lymphocytes...
  2. ncbi Protection against diabetes and improved NK/NKT cell performance in NOD.NK1.1 mice congenic at the NK complex
    C Carnaud
    Institut National de la Santé et de la Recherche Médicale Unité 25, Hopital Necker, Paris, France
    J Immunol 166:2404-11. 2001
    ..This could explain at the same time the multiple alterations of innate immunity reported in NOD mice and the fact that disease onset can be readily modified by boosting the innate immune system of the mouse...
  3. ncbi Accelerated beta-cell destruction in adoptively transferred autoimmune diabetes correlates with an increased expression of the genes coding for TNF-alpha and granzyme A in the intra-islet infiltrates
    C Mueller
    Department of Pathology, University of Bern, Switzerland
    Diabetes 44:112-7. 1995
    ..The effects of the observed enhanced TNF expression upon the pathogenesis of trIDDM are as yet unknown.(ABSTRACT TRUNCATED AT 250 WORDS)..
  4. ncbi Treatment with neutralizing antibodies specific for IL-1beta prevents cyclophosphamide-induced diabetes in nonobese diabetic mice
    C Cailleau
    INSERM U25, Hopital Necker, Paris, France
    Diabetes 46:937-40. 1997
    ..Our results show that IL-1beta is a critical effector molecule in this model of IDDM and that its specific inhibition could be an attractive target for therapeutic intervention...
  5. ncbi NK T cell-induced protection against diabetes in V alpha 14-J alpha 281 transgenic nonobese diabetic mice is associated with a Th2 shift circumscribed regionally to the islets and functionally to islet autoantigen
    V Laloux
    , , , Paris, France
    J Immunol 166:3749-56. 2001
    ..The protection from diabetes conferred by NK T cells is thus associated with a Th2 shift within islets directed against autoantigen such as glutamic acid decarboxylase. Our findings also demonstrate the key role of IL-4...
  6. ncbi Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes
    A Gonzalez
    Institut de Genetique et de Biologie Moleculaire et Cellulaire CNRS INSERM ULP, Strasbourg, France
    Nat Immunol 2:1117-25. 2001
    ..5 cells, permitting their full activation and attack of pancreatic islets; rather, it tempered the aggressiveness of the insulitic lesion and the extent of beta cell destruction...