- [Risk of infection in institutions for elderly people]J Carlet
Fondation Hopital Saint Joseph, 185 rue Raymond Losserand, 75674 Paris Cedex 14, France
Med Mal Infect 35:245-51. 2005..A strong cooperation between these long-term care facilities and nursing homes, general practitioners, healthcare team, and relatives is necessary...
- [Antibiotic strategy during septic shock]Jean Carlet
Service de Reanimation Polyvalente, Fondation Hopital Saint Joseph, Paris
Presse Med 35:528-32. 2006..Radical treatment of the source of infection, especially by surgery, should be combined with antibiotic treatment whenever possible...
- Epidemiology and control of antibiotic resistance in the intensive care unitJean Carlet
Intensive Care Unit, Fondation Hopital Saint Joseph, 185, rue Raymond Losserand, 75014 Paris, France
Curr Opin Infect Dis 17:309-16. 2004..The risk of cross-transmission of those strains is very high. This review focuses on recent data (2003 to the present) that may help understanding and dealing with this serious public health problem...
- Challenges in end-of-life care in the ICU. Statement of the 5th International Consensus Conference in Critical Care: Brussels, Belgium, April 2003Jean Carlet
Réanimation Polyvalente, Fondation Hopital St Joseph, 185 rue Raymond Losserand, 75674 Paris Cedex 14, France
Intensive Care Med 30:770-84. 2004..The patient must be given sufficient analgesia to alleviate pain and distress; if such analgesia hastens death, this "double effect" should not detract from the primary aim to ensure comfort...
- [Antibiotic therapy in serious infectious states]J Carlet
Service de Reanimation Polyvalente, Fondation Hopital Saint Joseph, 185, rue Raymond Losserand, 75674 Paris Cedex 14, France
Med Mal Infect 36:299-303. 2006..The appropriateness of empiric therapy is based on the delay before administration of the molecule, the bacterial resistance profile, and the kinetic and/or dynamic properties of the available antibiotics...
- Decision-making process, outcome, and 1-year quality of life of octogenarians referred for intensive care unit admissionMaite Garrouste-Orgeas
Medical ICU, Saint Joseph Hospital, 185 rue Raymond Losserand, 75014 Paris, France
Intensive Care Med 32:1045-51. 2006..To describe triage decisions and subsequent outcomes in octogenarians referred to an ICU...
- Opinions of families, staff, and patients about family participation in care in intensive care unitsMaite Garrouste-Orgeas
Medical ICU, Saint Joseph Hospital Network, 75014 Paris, France
J Crit Care 25:634-40. 2010....
- Managing intensive care units: make LOVE, not war!Jean Carlet
Groupe Hospitalier Paris Saint Joseph, Réanimation Polyvalente, 75014 Paris, France
J Crit Care 25:359.e9-359.e12. 2010....
- A continuous quality-improvement program reduces nosocomial infection rates in the ICUBenoit Misset
Medical Surgical Intensive Care Unit, Saint Joseph Hospital, 185 rue Raymond Losserand, 75614 Paris Cedex, France
Intensive Care Med 30:395-400. 2004..To assess the impact of a continuous quality-improvement program on nosocomial infection rates...
- Quality of life in patients aged 80 or over after ICU dischargeAlexis Tabah
Medical Surgical ICU, Saint Joseph Hospital Network, 185 rue Raymond Losserand, 75014 Paris, France
Crit Care 14:R2. 2010..Our objective was to describe self-sufficiency and quality of life one year after intensive care unit (ICU) discharge of patients aged 80 years or over...
- Impact of adverse events on outcomes in intensive care unit patientsMaite Garrouste Orgeas
Medical Surgical ICU, Saint Joseph Hospital Network, Paris, France
Crit Care Med 36:2041-7. 2008..To examine the association between predefined adverse events (AE) (including nosocomial infections) and intensive care unit (ICU) mortality, controlling for multiple adverse events in the same patient and confounding variables...
- Selected medical errors in the intensive care unit: results of the IATROREF study: parts I and IIMaite Garrouste-Orgeas
Service de Réanimation medico chirurgicale, Groupe Hospitalier Paris Saint Joseph, 185 rue Raymond Losserand, 75014 Paris, France
Am J Respir Crit Care Med 181:134-42. 2010..Identifying medical errors (MEs) that serve as indicators for iatrogenic risk is crucial for purposes of reporting and prevention...
- Perceptions of a 24-hour visiting policy in the intensive care unitMaite Garrouste-Orgeas
Medical Surgical Intensive Care Unit, Saint Joseph Hospital Network, Paris, France
Crit Care Med 36:30-5. 2008..To examine perceptions by intensive care unit (ICU) workers of unrestricted visitation, to measure visiting times, and to determine prevalence of symptoms of anxiety and depression in family members...
- Predicting whether the ICU can help older patients: score neededMaite Garrouste-Orgeas
Medical Surgical ICU, Saint Joseph Hospital, 75014 Paris, France
Crit Care 9:331-2. 2005..We have much to learn about matching the use of life-supporting treatments to the health-related values of older patients. A specific outcome-prediction score for older patients would help improve quality of care...
- Excess risk of death from intensive care unit-acquired nosocomial bloodstream infections: a reappraisalMaite Garrouste-Orgeas
Medical Surgical Intensive Care Unit, Saint Joseph Hospital, Paris, France corrected
Clin Infect Dis 42:1118-26. 2006..We investigated whether ICU-acquired BSI increased mortality (by > or = 10%) after adjustment for severity of infection at ICU admission and during the pre-BSI stay...
- Colonization with methicillin-resistant Staphylococcus aureus in ICU patients: morbidity, mortality, and glycopeptide useM Garrouste-Orgeas
, HÄµpital Saint Joseph, Paris, France
Infect Control Hosp Epidemiol 22:687-92. 2001..MRSA colonization influenced glycopeptide use even if an MRSA infection was not demonstrated; thus, an MRSA control program is warranted to decrease vancomycin use and to limit glycopeptide resistance in gram-positive cocci...
- [Detection of nasal colonization methicillin-resistant Staphylococcus aureus: a prospective study comparing real-time genic amplification assay vs selective chromogenic media]J C Nguyen Van
Laboratoire de Microbiologie Medicale, Fondation Hopital Saint Joseph, 185, rue Raymond Losserand 75674 Paris cedex 14, France
Pathol Biol (Paris) 54:285-92. 2006..Moreover, real-time genic amplification allows an early detection of meticillin resistant Staphylococcus aureus colonization, 2 hours compared to 1 or 2 days for culture...
- Fatal septic shock caused by Corynebacterium D2Vincent Audard
Medical-Surgical ICU, Saint Joseph Hospital, 185 rue Raymond Losserand, 75014, Paris, France
Intensive Care Med 29:1376-9. 2003..CONCLUSIONS: Corynebacterium D2 is known to cause chronic inflammation of the bladder and proximal urinary tract but can also cause severe septic shock in immunocompetent patients...
- Triaging patients to the ICU: a pilot study of factors influencing admission decisions and patient outcomesMaite Garrouste-Orgeas
Medical Surgical ICU, Saint Joseph Hospital, 185 rue Raymond Losserand, 75014 Paris, France
Intensive Care Med 29:774-81. 2003..To assess the appropriateness of ICU triage decisions. DESIGN. Prospective descriptive single-center study...
- Sepsis: time to reconsider the conceptJean Carlet
Intensive Care Unit, Infectious Diseases Department, Groupe Hospitalier Paris Saint Joseph, Paris, France
Crit Care Med 36:964-6. 2008..To discuss the difficulty in using the concept of sepsis for clinical trials and propose new ways for designing future trials for severe infections...
- Highly sensitive and efficient computer-assisted system for routine surveillance for surgical site infectionAnnie Chalfine
Infection Control Unit, Saint Joseph Hospital, Paris, France
Infect Control Hosp Epidemiol 27:794-801. 2006..We determined the sensitivity and specificity of a computer-assisted surveillance system, compared with a conventional method involving review of medical records, and the time saved with the computer-assisted system...
- Reducing surgical site infection incidence through a network: results from the French ISO-RAISIN surveillance systemP Astagneau
Coordinating Centre for Nosocomial Infection Control, Northern Region, Paris, France
J Hosp Infect 72:127-34. 2009..Active surveillance striving for a benchmark throughout a network is an effective strategy to reduce SSI incidence...
- Procalcitonin (PCT) is useful in predicting the bacterial origin of an acute circulatory failure in critically ill patientsC Cheval
, , 185 rue Raymond Losserand, F-75014 Paris, France
Intensive Care Med 26:S153-8. 2000..1-37,p=0.04). CONCLUSION: The increase of PCT is related to the appearance and severity of bacterial infection in ICU patients. Thus, PCT might be an interesting parameter for the diagnosis of bacterial infections in ICU patients...
- Prescribing indications based on successful clinical trials in sepsis: a difficult exerciseJ Carlet
Intensive Care Unit and Infectious Diseases Department, , Paris, France
Crit Care Med 34:525-9. 2006
- Monotherapy with a broad-spectrum beta-lactam is as effective as its combination with an aminoglycoside in treatment of severe generalized peritonitis: a multicenter randomized controlled trial. The Severe Generalized Peritonitis Study GroupH Dupont
Department of Surgical ICU, University Hospital Bichat, Paris, France
Antimicrob Agents Chemother 44:2028-33. 2000..In conclusion, the addition of AMK to TAZ does not seem to be necessary for the treatment of SGP, even after adjustment for the simplified acute physiology score (SAPS II) and type of SGP...
- The significance of distal bronchial samples with commensals in ventilator-associated pneumonia: colonizer or pathogen?Olivier Lambotte
, , 46 rue Henri Huchard, 75018 Paris, France
Chest 122:1389-99. 2002..The exposed/unexposed study found no difference in mortality. CONCLUSION: OCCs may behave like classic nosocomial pathogens in critically ill patients...
- Paresis acquired in the intensive care unit: a prospective multicenter studyBernard De Jonghe
Service de Reanimation Medicale, centre hospitalier de Poissy Saint Germain en Laye, 10 rue du Champ Gaillard, 78300 Poissy, France
JAMA 288:2859-67. 2002....
- Sepsis in European intensive care units: results of the SOAP studyJean-Louis Vincent
Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
Crit Care Med 34:344-53. 2006..In addition to age, a positive fluid balance was among the strongest prognostic factors for death. Patients with intensive care unit acquired sepsis have a worse outcome despite similar severity scores on intensive care unit admission...
- Applying the concept of healthcare-associated infections to hematology programsSami Chehata
Hematology Department, Henri Mondor Teaching Hospital, AP-HP and Paris 12 University, , France
Haematologica 91:1414-7. 2006..Healthcare-associated infections should be preferred to nosocomial infections--which underestimates half of the healthcare-associated infections--as quality indicators for preventive programs...
- Early goal-directed therapy of septic shock in the emergency room: who could honestly remain skeptical?Jean Carlet
Crit Care Med 34:2842-3. 2006
- Looking at subgroups in an inhomogeneous population does not make these subgroups more homogeneousJean Carlet
Intensive Care Med 30:1497. 2004
- Moxifloxacin monotherapy is effective in hospitalized patients with community-acquired pneumonia: the MOTIV study--a randomized clinical trialAntoni Torres
Servei de Pneumologia i Allergia Respiratoria, Institut Clinic del Torax, Hospital Clinic de Barcelona, Spain
Clin Infect Dis 46:1499-509. 2008....
- Surviving intensive care: a report from the 2002 Brussels RoundtableDerek C Angus
CRISMA, Laboratory, Department of Critical Care Medicine, School of Medicine, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA
Intensive Care Med 29:368-77. 2003..Specific interventions that show promise for improving care include ICU discharge screening tools and ICU follow-up clinics...
- The PIRO concept: O is for organ dysfunctionJean-Louis Vincent
Department of Intensive Care, Erasme Hospital, Free University of Brussels, Belgium
Crit Care 7:260-4. 2003
- Health services research rounds: patient-centered outcomesSean P Keenan
University of British Columbia, Vancouver, British Columbia, Canada
J Crit Care 17:221-34. 2002
- New method of classifying infections in critically ill patientsJonathan Cohen
Department of Medicine, Brighton and Sussex Medical School, Falmer, UK
Crit Care Med 32:1510-26. 2004..CONCLUSION: We have described a novel approach to permit a better assessment of the contribution made by the infection to mortality in patients with sepsis or septic shock...