Florence Cammas

Summary

Country: France

Publications

  1. ncbi Germ cell expression of the transcriptional co-repressor TIF1beta is required for the maintenance of spermatogenesis in the mouse
    Philipp Weber
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP163, 67404 Illkirch Cedex, France
    Development 129:2329-37. 2002
  2. ncbi Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction
    Florence Cammas
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP163, 67404 Illkirch Cedex, France
    J Cell Sci 115:3439-48. 2002
  3. ncbi Dynamic and selective interactions of the transcriptional corepressor TIF1 beta with the heterochromatin protein HP1 isotypes during cell differentiation
    Florence Cammas
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP10142, 67404 Illkirch Cedex, France
    Differentiation 75:627-37. 2007
  4. pmc Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation
    Florence Cammas
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP10142, 67404 Illkirch, France
    Genes Dev 18:2147-60. 2004
  5. pmc Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
    Benjamin Herquel
    Department of Functional Genomics and Cancer, Institut de Genetique et de Biologie Moleculaire et Cellulaire, 1 rue Laurent Fries, 67404 Illkirch Cedex, France
    Proc Natl Acad Sci U S A 108:8212-7. 2011
  6. doi Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA
    Benjamin Herquel
    Department of Functional Genomics and Cancer, Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France
    Nat Struct Mol Biol 20:339-46. 2013
  7. pmc Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
    Beena Patricia Jeevan-Raj
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Institut National de Santé et de Recherche Médicale Unité 964 Centre National de Recherche Scientifique Unité Mixte de Recherche 7104, Universite de Strasbourg, 67404 Illkirch, France
    J Exp Med 208:1649-60. 2011
  8. pmc Disruption of the interaction between transcriptional intermediary factor 1{beta} and heterochromatin protein 1 leads to a switch from DNA hyper- to hypomethylation and H3K9 to H3K27 trimethylation on the MEST promoter correlating with gene reactivation
    Raphaël Riclet
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Centre National de la Recherche Scientifique Institut National de la Santé et de la Recherche Médicale Université Louis Pasteur Collège de France, Illkirch Cedex, France
    Mol Biol Cell 20:296-305. 2009
  9. ncbi TRIM involvement in transcriptional regulation
    Florence Cammas
    Department of Functional Genomics, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, Illkirch, France
    Adv Exp Med Biol 770:59-76. 2012
  10. ncbi Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha
    Konstantin Khetchoumian
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Department of Functional Genomics, Centre National de la Recherche Scientifique UMR7104, Universite Louis Pasteur, College de France, Illkirch, France
    Nat Genet 39:1500-6. 2007

Collaborators

  • Pierre Chambon
  • Manuel Mark
  • Irwin Davidson
  • Igor Martianov
  • Jing H Wang
  • Jessica Zucman-Rossi
  • Bernardo Reina-San-Martin
  • Stephen Goff
  • Regine Losson
  • Benjamin Herquel
  • Konstantin Khetchoumian
  • Khalid Ouararhni
  • Beena Patricia Jeevan-Raj
  • Thierry Lerouge
  • Sarah Sanglier-Cianferani
  • Mihaela Ignat
  • Raphaël Riclet
  • Marius Teletin
  • Daniel Wolf
  • Delphine Quenet
  • Daniel Metzger
  • Philipp Weber
  • Celine Keime
  • Bernard Jost
  • Tao Ye
  • Stéphanie Le Gras
  • Guillaume Béchade
  • Adeline Page
  • Vincent Heyer
  • Isabelle Robert
  • Alain Van Dorsselaer
  • Frederick W Alt
  • Ali Hamiche
  • Hans Juergen Thiesen
  • Jean Luc Vonesch
  • Dirk Koczan
  • Mariam Chendeb
  • Laetitia Fouillen
  • Francoise Dantzer
  • Véronique Gasser
  • Christelle Thibault
  • Johan Tisserand
  • Christelle Gerard

Detail Information

Publications12

  1. ncbi Germ cell expression of the transcriptional co-repressor TIF1beta is required for the maintenance of spermatogenesis in the mouse
    Philipp Weber
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP163, 67404 Illkirch Cedex, France
    Development 129:2329-37. 2002
    ....
  2. ncbi Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction
    Florence Cammas
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP163, 67404 Illkirch Cedex, France
    J Cell Sci 115:3439-48. 2002
    ..Collectively, these data provide compelling evidence for a dynamic nuclear compartmentalization of TIF1beta that is regulated during cell differentiation through a mechanism that requires HP1 interaction...
  3. ncbi Dynamic and selective interactions of the transcriptional corepressor TIF1 beta with the heterochromatin protein HP1 isotypes during cell differentiation
    Florence Cammas
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP10142, 67404 Illkirch Cedex, France
    Differentiation 75:627-37. 2007
    ....
  4. pmc Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation
    Florence Cammas
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, BP10142, 67404 Illkirch, France
    Genes Dev 18:2147-60. 2004
    ..Collectively, these data demonstrate that the interaction between TIF1beta and HP1 proteins is essential for progression through differentiation by regulating the expression of endoderm differentiation master players...
  5. pmc Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma
    Benjamin Herquel
    Department of Functional Genomics and Cancer, Institut de Genetique et de Biologie Moleculaire et Cellulaire, 1 rue Laurent Fries, 67404 Illkirch Cedex, France
    Proc Natl Acad Sci U S A 108:8212-7. 2011
    ..These results demonstrate that the TIF1-related subfamily of TRIM proteins interact both physically and functionally to modulate HCC formation in mice...
  6. doi Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA
    Benjamin Herquel
    Department of Functional Genomics and Cancer, Institut de Genetique et de Biologie Moleculaire et Cellulaire, Illkirch, France
    Nat Struct Mol Biol 20:339-46. 2013
    ..These data reinforce the role of the TRIM family of proteins in retroviral restriction and antiviral defense and provide an example of an ERV-derived oncogenic regulatory network...
  7. pmc Epigenetic tethering of AID to the donor switch region during immunoglobulin class switch recombination
    Beena Patricia Jeevan-Raj
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Institut National de Santé et de Recherche Médicale Unité 964 Centre National de Recherche Scientifique Unité Mixte de Recherche 7104, Universite de Strasbourg, 67404 Illkirch, France
    J Exp Med 208:1649-60. 2011
    ..We propose that KAP1 and HP1 tether AID to H3K9me3 residues at the donor switch region, thus providing a mechanism linking AID to epigenetic modifications during CSR...
  8. pmc Disruption of the interaction between transcriptional intermediary factor 1{beta} and heterochromatin protein 1 leads to a switch from DNA hyper- to hypomethylation and H3K9 to H3K27 trimethylation on the MEST promoter correlating with gene reactivation
    Raphaël Riclet
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Centre National de la Recherche Scientifique Institut National de la Santé et de la Recherche Médicale Université Louis Pasteur Collège de France, Illkirch Cedex, France
    Mol Biol Cell 20:296-305. 2009
    ..Interestingly, we provide evidence that the imprinted MEST allele DNA methylation is insensitive to TIF1beta loss of function, whereas the nonimprinted allele is regulated through a distinct TIF1beta-DNA methylation mechanism...
  9. ncbi TRIM involvement in transcriptional regulation
    Florence Cammas
    Department of Functional Genomics, Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS INSERM ULP College de France, Illkirch, France
    Adv Exp Med Biol 770:59-76. 2012
    ..In this chapter, we will consider the molecular interactions made by these TRIM proteins and will attempt to clarify some of the molecular mechanisms underlying their regulatory effect on transcription...
  10. ncbi Loss of Trim24 (Tif1alpha) gene function confers oncogenic activity to retinoic acid receptor alpha
    Konstantin Khetchoumian
    Institut de Genetique et de Biologie Moleculaire et Cellulaire, Department of Functional Genomics, Centre National de la Recherche Scientifique UMR7104, Universite Louis Pasteur, College de France, Illkirch, France
    Nat Genet 39:1500-6. 2007
    ..Our results not only provide genetic evidence that Trim24 and Rara co-regulate hepatocarcinogenesis in an antagonistic manner but also suggest that aberrant activation of Rara is deleterious to liver homeostasis...
  11. doi The histone subcode: poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha
    Delphine Quenet
    Département IDG, UMR7175, ESBS, Bld S Brant, 67412 Illkirch, France
    FASEB J 22:3853-65. 2008
    ..Losson, R., Dantzer, F. The histone subcode: poly(ADP-ribose) polymerase-1 (Parp-1) and Parp-2 control cell differentiation by regulating the transcriptional intermediary factor TIF1beta and the heterochromatin protein HP1alpha...
  12. pmc Primer binding site-dependent restriction of murine leukemia virus requires HP1 binding by TRIM28
    Daniel Wolf
    Department of Biochemistry and Molecular Biophysics, Howard Hughes Medical Institute, Columbia University, HHSC 1310, 701 West 168th Street, New York, NY 10032, USA
    J Virol 82:4675-9. 2008
    ..Here we show, using a cell line with a point mutation in the HP1 binding domain of TRIM28, that interaction with HP1 is absolutely required for the PBS-dependent restriction of MLV in the F9 EC cell line...