I Callebaut

Summary

Country: France

Publications

  1. pmc Identification, characterization and metagenome analysis of oocyte-specific genes organized in clusters in the mouse genome
    Amélie Paillisson
    Physiologie de la Reproduction et des Comportements, UMR 6175 INRA CNRS Université François Rabelais de Tours Haras Nationaux, 37380 Nouzilly, France
    BMC Genomics 6:76. 2005
  2. pmc HYR, an extracellular module involved in cellular adhesion and related to the immunoglobulin-like fold
    I Callebaut
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universite Paris 6, France
    Protein Sci 9:1382-90. 2000
  3. ncbi request reprint The BAH (bromo-adjacent homology) domain: a link between DNA methylation, replication and transcriptional regulation
    I Callebaut
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universite Paris 6, France
    FEBS Lett 446:189-93. 1999
  4. ncbi request reprint From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair
    I Callebaut
    Systèmes moléculaires and Biologie structurale, Laboratoire de Minéralogie Cristallographie, CNRS URA09, Universite Paris 6, France
    FEBS Lett 400:25-30. 1997
  5. ncbi request reprint Hydrophobic cluster analysis reveals a third chromodomain in the Tetrahymena Pdd1p protein of the chromo superfamily
    I Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS URA09, Universite Paris 6, France
    Biochem Biophys Res Commun 235:103-7. 1997
  6. ncbi request reprint The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis
    I Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS UMR C7590, Paris, France
    Cell Mol Life Sci 54:880-91. 1998
  7. ncbi request reprint Structural features of prions explored by sequence analysis. II. A PrP(Sc) model
    J P Mornon
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    Cell Mol Life Sci 59:2144-54. 2002
  8. ncbi request reprint uDENN, DENN, and dDENN: indissociable domains in Rab and MAP kinases signaling pathways
    E Levivier
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, Paris Cedex 05, 75252, France
    Biochem Biophys Res Commun 287:688-95. 2001
  9. ncbi request reprint Nucleotide-binding domains of human cystic fibrosis transmembrane conductance regulator: detailed sequence analysis and three-dimensional modeling of the heterodimer
    I Callebaut
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    Cell Mol Life Sci 61:230-42. 2004
  10. ncbi request reprint Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives
    I Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS URA 09, UP6 UP7, Paris, France
    Cell Mol Life Sci 53:621-45. 1997

Collaborators

  • J P Mornon
  • A Poupon
  • P Durand
  • G Labesse
  • M Souchet
  • J de Gunzburg
  • Howard Worman
  • I Mouro
  • P Monget
  • N Dastugue
  • N Wolff
  • R Eudes
  • Amélie Paillisson
  • J P Cartron
  • P Mulsant
  • D Moshous
  • B Gilquin
  • K Courchay
  • S Zinn-Justin
  • W El Nemer
  • E Brault
  • C Laguri
  • E Levivier
  • P Gane
  • F Marques
  • D Gilges
  • P Hermand
  • F Lin
  • V Thoreau
  • C Madry
  • L Ayadi
  • F Carbonnet
  • P Lehn
  • Martine Bontoux
  • Rozenn Dalbies-Tran
  • Daniel Vaiman
  • C Ferec
  • Sébastien Dadé
  • Q Ye
  • D Monniaux
  • F Lecerf
  • L Schibler
  • C Pisselet
  • L Goutebroze
  • J M Elsen
  • Y Bertrand
  • J Riquet
  • F Le Deist
  • E Cribiu
  • M Lamarine
  • I Tezcan
  • J P de Villartay
  • A Fischer
  • A Gautreau
  • N Philippe
  • O Sanal
  • R de Chasseval
  • R Romi-Lebrun
  • B Goud
  • J Thimonier
  • J Teyssier
  • L Bodin
  • Y Cognie
  • B Corneo
  • I Lanneluc
  • G Thomas
  • S Fabre
  • C L Van Kim
  • T P Calmels
  • M Cavazzana-Calvo
  • N Chitour
  • A M D'Ambrosio
  • Y Colin
  • P Schatt
  • P H Romeo
  • V Cacheux
  • D L Blake
  • P Bailly
  • C G Gahmberg
  • M W McBurney
  • E Perret
  • J L Moreau
  • G Peaucellier
  • I S Skerjanc
  • M A Vinit
  • E Ihanus
  • M Huet
  • I Vigon
  • M Paulin-Levasseur
  • J C Lozano

Detail Information

Publications35

  1. pmc Identification, characterization and metagenome analysis of oocyte-specific genes organized in clusters in the mouse genome
    Amélie Paillisson
    Physiologie de la Reproduction et des Comportements, UMR 6175 INRA CNRS Université François Rabelais de Tours Haras Nationaux, 37380 Nouzilly, France
    BMC Genomics 6:76. 2005
    ..In an attempt to identify novel oocyte-specific genes in the mouse, we have used an in silico subtraction methodology, and we have focused our attention on genes that are organized in genomic clusters...
  2. pmc HYR, an extracellular module involved in cellular adhesion and related to the immunoglobulin-like fold
    I Callebaut
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universite Paris 6, France
    Protein Sci 9:1382-90. 2000
    ....
  3. ncbi request reprint The BAH (bromo-adjacent homology) domain: a link between DNA methylation, replication and transcriptional regulation
    I Callebaut
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universite Paris 6, France
    FEBS Lett 446:189-93. 1999
    ..The BAH module might therefore play an important role by linking DNA methylation, replication and transcriptional regulation...
  4. ncbi request reprint From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair
    I Callebaut
    Systèmes moléculaires and Biologie structurale, Laboratoire de Minéralogie Cristallographie, CNRS URA09, Universite Paris 6, France
    FEBS Lett 400:25-30. 1997
    ..90-100 amino acids...
  5. ncbi request reprint Hydrophobic cluster analysis reveals a third chromodomain in the Tetrahymena Pdd1p protein of the chromo superfamily
    I Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS URA09, Universite Paris 6, France
    Biochem Biophys Res Commun 235:103-7. 1997
    ..The results also demonstrate the power of HCA in identifying relationships which are not detected by conventional methods of sequence analysis...
  6. ncbi request reprint The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysis
    I Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS UMR C7590, Paris, France
    Cell Mol Life Sci 54:880-91. 1998
    ..Moreover, the presence of a plant homeodomain finger-like motif in the last quarter of the RAG2 sequence suggests a potential interaction of this domain with chromatin components...
  7. ncbi request reprint Structural features of prions explored by sequence analysis. II. A PrP(Sc) model
    J P Mornon
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    Cell Mol Life Sci 59:2144-54. 2002
    ..Some comments are also devoted to a comparison of the yeast Ure2p prion and animal prions...
  8. ncbi request reprint uDENN, DENN, and dDENN: indissociable domains in Rab and MAP kinases signaling pathways
    E Levivier
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, Paris Cedex 05, 75252, France
    Biochem Biophys Res Commun 287:688-95. 2001
    ..These however share conserved amino acids which could play a key role in the DENN functions...
  9. ncbi request reprint Nucleotide-binding domains of human cystic fibrosis transmembrane conductance regulator: detailed sequence analysis and three-dimensional modeling of the heterodimer
    I Callebaut
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
    Cell Mol Life Sci 61:230-42. 2004
    ..Moreover, additional CFTR-specific features can be identified at the subunit interface, which may play critical roles in active site interdependence and are uncommon in other NBD dimers...
  10. ncbi request reprint Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectives
    I Callebaut
    Systèmes moléculaires et Biologie structurale, LMCP, CNRS URA 09, UP6 UP7, Paris, France
    Cell Mol Life Sci 53:621-45. 1997
    ..Since the last review of HCA published in 1990 [1], significant improvements have been made and several new facets have been addressed. Here we wish to update and summarize this information...
  11. ncbi request reprint Structural features of prions explored by sequence analysis I. Sequence data
    J P Mornon
    Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, France
    Cell Mol Life Sci 59:1366-76. 2002
    ....
  12. ncbi request reprint Trigger factor, one of the Escherichia coli chaperone proteins, is an original member of the FKBP family
    I Callebaut
    Laboratoire de Minéralogie Cristallographie, CNRS URA09, Universités Paris 6, France
    FEBS Lett 374:211-5. 1995
    ....
  13. ncbi request reprint RUN domains: a new family of domains involved in Ras-like GTPase signaling
    I Callebaut
    Systèmes moléculaires et Biologie structurale, CNRS UMR 7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris 05, Cedex, France
    Trends Biochem Sci 26:79-83. 2001
    ..RUN domains are present in several proteins that are linked particularly to the functions of GTPases in the Rap and Rab families. They could hence play an important role in multiple Ras-like GTPase signaling pathways...
  14. ncbi request reprint The uteroglobin fold
    I Callebaut
    Systèmes moléculaires et Biologie structurale, Laboratoire de Minéralogie Cristallographie Paris LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris, France
    Ann N Y Acad Sci 923:90-112. 2000
    ....
  15. pmc The human EBNA-2 coactivator p100: multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster development
    I Callebaut
    Laboratoire de Minéralogie Cristallographie, CNRS URA09, Universite, Paris 6, France
    Biochem J 321:125-32. 1997
    ..We named this heretofore undescribed domain the 'tudor domain' and highlight within it five invariant residues which could be involved in one of the essential roles played by these proteins...
  16. ncbi request reprint Structural characterization of the LEM motif common to three human inner nuclear membrane proteins
    C Laguri
    Departement d Ingenierie et d Etudes des Proteines, CEA Saclay, 91191, Gif sur Yvette, France
    Structure 9:503-11. 2001
    ..In particular, all LAP2 isoforms share an N-terminal segment composed of such a LEM domain that is connected to a highly divergent LEM-like domain by a linker that is probably unstructured...
  17. ncbi request reprint Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
    D Moshous
    Développement Normal et Pathologique, du Système Immunitaire, INSERM U429, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015, Paris, France
    Cell 105:177-86. 2001
    ..Protein sequence analysis strongly suggests that Artemis belongs to the metallo-beta-lactamase superfamily...
  18. ncbi request reprint Structural analysis of emerin, an inner nuclear membrane protein mutated in X-linked Emery-Dreifuss muscular dystrophy
    N Wolff
    Departement d Ingenierie et d Etudes des Proteines, CEA Saclay, Gif sur Yvette, France
    FEBS Lett 501:171-6. 2001
    ..The existence of a conserved solvent-exposed surface on the LEM domains of LAP2 and emerin is discussed, as well as the nature of a possible common target...
  19. pmc An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 protein
    I Callebaut
    Département des Macromolécules Biologiques, Centre National de la Recherche Scientifique URA09, Paris, France
    Proc Natl Acad Sci U S A 89:6270-4. 1992
    ..Hsp binding immunophilin may be involved in a number of immunological, endocrinological, and chaperone-mediated pathways...
  20. ncbi request reprint Nucleotide binding domains of human CFTR: a structural classification of critical residues and disease-causing mutations
    R Eudes
    Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252, Paris Cedex 05, France
    Cell Mol Life Sci 62:2112-23. 2005
    ..In particular, a cluster of aromatic amino acids, which includes F508 and straddles the two NBDs, might be directly involved in the interaction of the NBD1/NBD2 heterodimer with the channel-forming membrane-spanning domains...
  21. ncbi request reprint Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structures
    I Callebaut
    Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Paris VI et Paris VII, case 115, 4, place Jussieu, 75252 Paris Cedex 05, France
    Transfus Clin Biol 13:70-84. 2006
    ..These results provide a basis to further understand the structure/function relationships of Rh proteins, and the alterations occurring in variant phenotypes...
  22. ncbi request reprint Normal membrane localization and actin association of the NF2 tumor suppressor protein are dependent on folding of its N-terminal domain
    E Brault
    , U434 INSERM-CEPH Fondation Jean Dausset, 75010 Paris, France
    J Cell Sci 114:1901-12. 2001
    ..These results suggest that loss of activity of several naturally occurring schwannomin mutants is due to disruption of the fold of the N-terminal domain, leading to loss of both membrane localization and actin association...
  23. ncbi request reprint Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8)
    V Thoreau
    UPRES 2622, CHU de Poitiers, France
    Biochem Biophys Res Commun 257:577-83. 1999
    ..This raises the possibility that syntaxin 8 may also be involved in such regulations...
  24. ncbi request reprint Characterization of the laminin binding domains of the Lutheran blood group glycoprotein
    W El Nemer
    INSERM U76, Institut National de la Transfusion Sanguine, Paris 75015, France and CNRS UMR7590, Universités Paris 6 et Paris 7, Paris 75005, France
    J Biol Chem 276:23757-62. 2001
    ..Neither the RGD nor the N-glycosylation motifs present in IgSF domain 3 were involved in laminin binding...
  25. doi request reprint Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfaces
    J P Mornon
    Universite Pierre et Marie Curie Paris 6, IMPMC UMR7590, Campus Boucicaut, 140 rue de Lourmel, Paris 75015, France
    Cell Mol Life Sci 65:2594-612. 2008
    ..These observations allow new insights into the ATP-binding sites asymmetry and into the molecular consequences of the F508 deletion, which is the most common cystic fibrosis mutation...
  26. ncbi request reprint MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerin
    F Lin
    Departments of Medicine and of Anatomy and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Biol Chem 275:4840-7. 2000
    ..The LEM module is also present in two proteins of Caenorhabditis elegans. These results show that MAN1 is an integral protein of the inner nuclear membrane that shares the LEM module with other proteins of this subcellular localization...
  27. ncbi request reprint Functional and structural characterization of the prp3 binding domain of the yeast prp4 splicing factor
    L Ayadi
    Centre de Génétique Moléculaire du CNRS, Laboratoire Propre Associé à l Université P and M Curie, Gif sur Yvette, 91198, France
    J Mol Biol 284:673-87. 1998
    ..This surface could be used as a scaffold for generating an RNA-protein complex...
  28. ncbi request reprint Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
    J Pastorek
    Institute of Virology, Slovak Academy of Sciences, Bratislava
    Oncogene 9:2877-88. 1994
    ..In addition, the analysis of biological consequences of MN expression of NIH3T3 cells provides the evidence in favour of MN protein involvement in control of cell proliferation and transformation...
  29. ncbi request reprint Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBR
    Q Ye
    Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
    J Biol Chem 272:14983-9. 1997
    ..The modular domain organization of HP1-type proteins and LBR can explain some of the diverse protein-protein interactions at the chromatin-lamina-membrane interface of the nuclear envelope...
  30. ncbi request reprint Kx, a quantitatively minor protein from human erythrocytes, is palmitoylated in vivo
    F Carbonnet
    Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, Paris, 75015, France
    Biochem Biophys Res Commun 250:569-74. 1998
    ..Palmitoylation of one or several of these cysteines might contribute to anchor the cytoplasmic portion of the Kx protein to the inner surface of red cell membrane...
  31. ncbi request reprint The characterization of murine BCMA gene defines it as a new member of the tumor necrosis factor receptor superfamily
    C Madry
    INSERM CJF 95 02, Faculte de Medecine Paris Sud, Universite Paris XI, Clamart, France
    Int Immunol 10:1693-702. 1998
    ..Human BCMA is the first member of the TNFR family to be implicated in a chromosomal translocation...
  32. pmc Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewes
    P Mulsant
    Institut National de la Recherche Agronomique, Laboratoire de Genetique Cellulaire, BP, 27, 31326 Castanet Tolosan, France
    Proc Natl Acad Sci U S A 98:5104-9. 2001
    ..It is suggested that in FecB(B)/FecB(B) ewes, BMPR-IB would be inactivated partially, leading to an advanced differentiation of granulosa cells and an advanced maturation of ovulatory follicles...
  33. ncbi request reprint Binding sites of leukocyte beta 2 integrins (LFA-1, Mac-1) on the human ICAM-4/LW blood group protein
    P Hermand
    INSERM U76, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
    J Biol Chem 275:26002-10. 2000
    ..These data suggest that the binding site for LFA-1 on ICAM-4 overlaps but is distinct from the Mac-1 binding site...
  34. ncbi request reprint A new subfamily of high molecular mass CDC2-related kinases with PITAI/VRE motifs
    F Marques
    Laboratoire Arago, CNRS UMR 7628 Université Paris VI, BP 44, Banyuls sur mer Cedex, F 66651, France
    Biochem Biophys Res Commun 279:832-7. 2000
    ..CDC2L5 overexpressed in mammalian cells is an approximately 170-kDa nuclear protein. The mRNA is present during the sea urchin early embryogenesis and is ubiquitously expressed in human tissues...
  35. pmc Polydom: a secreted protein with pentraxin, complement control protein, epidermal growth factor and von Willebrand factor A domains
    D Gilges
    INSERM U474, Maternite Port Royal, 123 Bld de Port Royal 75014 Paris, France
    Biochem J 352:49-59. 2000
    ..The particular multidomain structure of the encoded protein suggests an important biological role in cellular adhesion and/or in the immune system...