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Genomes and Genes | I CallebautSummaryCountry: France Publications
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Publications
Identification, characterization and metagenome analysis of oocyte-specific genes organized in clusters in the mouse genomeAmélie Paillisson
Physiologie de la Reproduction et des Comportements, UMR 6175 INRA CNRS Université François Rabelais de Tours Haras Nationaux, 37380 Nouzilly, France
BMC Genomics 6:76. 2005..In an attempt to identify novel oocyte-specific genes in the mouse, we have used an in silico subtraction methodology, and we have focused our attention on genes that are organized in genomic clusters...- HYR, an extracellular module involved in cellular adhesion and related to the immunoglobulin-like foldI Callebaut
Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universite Paris 6, France
Protein Sci 9:1382-90. 2000.... 
The BAH (bromo-adjacent homology) domain: a link between DNA methylation, replication and transcriptional regulationI Callebaut
Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universite Paris 6, France
FEBS Lett 446:189-93. 1999..The BAH module might therefore play an important role by linking DNA methylation, replication and transcriptional regulation...- From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repairI Callebaut
Systèmes moléculaires and Biologie structurale, Laboratoire de Minéralogie Cristallographie, CNRS URA09, Universite Paris 6, France
FEBS Lett 400:25-30. 1997..90-100 amino acids... - Hydrophobic cluster analysis reveals a third chromodomain in the Tetrahymena Pdd1p protein of the chromo superfamilyI Callebaut
Systèmes moléculaires et Biologie structurale, LMCP, CNRS URA09, Universite Paris 6, France
Biochem Biophys Res Commun 235:103-7. 1997..The results also demonstrate the power of HCA in identifying relationships which are not detected by conventional methods of sequence analysis... - The V(D)J recombination activating protein RAG2 consists of a six-bladed propeller and a PHD fingerlike domain, as revealed by sequence analysisI Callebaut
Systèmes moléculaires et Biologie structurale, LMCP, CNRS UMR C7590, Paris, France
Cell Mol Life Sci 54:880-91. 1998..Moreover, the presence of a plant homeodomain finger-like motif in the last quarter of the RAG2 sequence suggests a potential interaction of this domain with chromatin components... - Structural features of prions explored by sequence analysis. II. A PrP(Sc) modelJ P Mornon
Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
Cell Mol Life Sci 59:2144-54. 2002..Some comments are also devoted to a comparison of the yeast Ure2p prion and animal prions... - uDENN, DENN, and dDENN: indissociable domains in Rab and MAP kinases signaling pathwaysE Levivier
Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, Paris Cedex 05, 75252, France
Biochem Biophys Res Commun 287:688-95. 2001..These however share conserved amino acids which could play a key role in the DENN functions... - Nucleotide-binding domains of human cystic fibrosis transmembrane conductance regulator: detailed sequence analysis and three-dimensional modeling of the heterodimerI Callebaut
Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris Cedex 05, France
Cell Mol Life Sci 61:230-42. 2004..Moreover, additional CFTR-specific features can be identified at the subunit interface, which may play critical roles in active site interdependence and are uncommon in other NBD dimers... - Deciphering protein sequence information through hydrophobic cluster analysis (HCA): current status and perspectivesI Callebaut
Systèmes moléculaires et Biologie structurale, LMCP, CNRS URA 09, UP6 UP7, Paris, France
Cell Mol Life Sci 53:621-45. 1997..Since the last review of HCA published in 1990 [1], significant improvements have been made and several new facets have been addressed. Here we wish to update and summarize this information... - Structural features of prions explored by sequence analysis I. Sequence dataJ P Mornon
Systèmes moléculaires and Biologie structurale, LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, France
Cell Mol Life Sci 59:1366-76. 2002.... - Trigger factor, one of the Escherichia coli chaperone proteins, is an original member of the FKBP familyI Callebaut
Laboratoire de Minéralogie Cristallographie, CNRS URA09, Universités Paris 6, France
FEBS Lett 374:211-5. 1995.... - RUN domains: a new family of domains involved in Ras-like GTPase signalingI Callebaut
Systèmes moléculaires et Biologie structurale, CNRS UMR 7590, Universités Paris 6 and Paris 7, case 115, 4 place Jussieu, 75252 Paris 05, Cedex, France
Trends Biochem Sci 26:79-83. 2001..RUN domains are present in several proteins that are linked particularly to the functions of GTPases in the Rap and Rab families. They could hence play an important role in multiple Ras-like GTPase signaling pathways... - The uteroglobin foldI Callebaut
Systèmes moléculaires et Biologie structurale, Laboratoire de Minéralogie Cristallographie Paris LMCP, CNRS UMR 7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252 Paris, France
Ann N Y Acad Sci 923:90-112. 2000.... - The human EBNA-2 coactivator p100: multidomain organization and relationship to the staphylococcal nuclease fold and to the tudor protein involved in Drosophila melanogaster developmentI Callebaut
Laboratoire de Minéralogie Cristallographie, CNRS URA09, Universite, Paris 6, France
Biochem J 321:125-32. 1997..We named this heretofore undescribed domain the 'tudor domain' and highlight within it five invariant residues which could be involved in one of the essential roles played by these proteins... - Structural characterization of the LEM motif common to three human inner nuclear membrane proteinsC Laguri
Departement d Ingenierie et d Etudes des Proteines, CEA Saclay, 91191, Gif sur Yvette, France
Structure 9:503-11. 2001..In particular, all LAP2 isoforms share an N-terminal segment composed of such a LEM domain that is connected to a highly divergent LEM-like domain by a linker that is probably unstructured... - Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiencyD Moshous
Développement Normal et Pathologique, du Système Immunitaire, INSERM U429, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015, Paris, France
Cell 105:177-86. 2001..Protein sequence analysis strongly suggests that Artemis belongs to the metallo-beta-lactamase superfamily... - Structural analysis of emerin, an inner nuclear membrane protein mutated in X-linked Emery-Dreifuss muscular dystrophyN Wolff
Departement d Ingenierie et d Etudes des Proteines, CEA Saclay, Gif sur Yvette, France
FEBS Lett 501:171-6. 2001..The existence of a conserved solvent-exposed surface on the LEM domains of LAP2 and emerin is discussed, as well as the nature of a possible common target... - An immunophilin that binds M(r) 90,000 heat shock protein: main structural features of a mammalian p59 proteinI Callebaut
Département des Macromolécules Biologiques, Centre National de la Recherche Scientifique URA09, Paris, France
Proc Natl Acad Sci U S A 89:6270-4. 1992..Hsp binding immunophilin may be involved in a number of immunological, endocrinological, and chaperone-mediated pathways... - Nucleotide binding domains of human CFTR: a structural classification of critical residues and disease-causing mutationsR Eudes
Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Paris 6 et Paris 7, case 115, 4 place Jussieu, 75252, Paris Cedex 05, France
Cell Mol Life Sci 62:2112-23. 2005..In particular, a cluster of aromatic amino acids, which includes F508 and straddles the two NBDs, might be directly involved in the interaction of the NBD1/NBD2 heterodimer with the channel-forming membrane-spanning domains... - Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structuresI Callebaut
Département de Biologie Structurale, IMPMC, CNRS UMR7590, Universités Paris VI et Paris VII, case 115, 4, place Jussieu, 75252 Paris Cedex 05, France
Transfus Clin Biol 13:70-84. 2006..These results provide a basis to further understand the structure/function relationships of Rh proteins, and the alterations occurring in variant phenotypes... - Normal membrane localization and actin association of the NF2 tumor suppressor protein are dependent on folding of its N-terminal domainE Brault
, U434 INSERM-CEPH Fondation Jean Dausset, 75010 Paris, France
J Cell Sci 114:1901-12. 2001..These results suggest that loss of activity of several naturally occurring schwannomin mutants is due to disruption of the fold of the N-terminal domain, leading to loss of both membrane localization and actin association... - Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8)V Thoreau
UPRES 2622, CHU de Poitiers, France
Biochem Biophys Res Commun 257:577-83. 1999..This raises the possibility that syntaxin 8 may also be involved in such regulations... - Characterization of the laminin binding domains of the Lutheran blood group glycoproteinW El Nemer
INSERM U76, Institut National de la Transfusion Sanguine, Paris 75015, France and CNRS UMR7590, Universités Paris 6 et Paris 7, Paris 75005, France
J Biol Chem 276:23757-62. 2001..Neither the RGD nor the N-glycosylation motifs present in IgSF domain 3 were involved in laminin binding... 
Atomic model of human cystic fibrosis transmembrane conductance regulator: membrane-spanning domains and coupling interfacesJ P Mornon
Universite Pierre et Marie Curie Paris 6, IMPMC UMR7590, Campus Boucicaut, 140 rue de Lourmel, Paris 75015, France
Cell Mol Life Sci 65:2594-612. 2008..These observations allow new insights into the ATP-binding sites asymmetry and into the molecular consequences of the F508 deletion, which is the most common cystic fibrosis mutation...- MAN1, an inner nuclear membrane protein that shares the LEM domain with lamina-associated polypeptide 2 and emerinF Lin
Departments of Medicine and of Anatomy and Cell Biology, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Biol Chem 275:4840-7. 2000..The LEM module is also present in two proteins of Caenorhabditis elegans. These results show that MAN1 is an integral protein of the inner nuclear membrane that shares the LEM module with other proteins of this subcellular localization... - Functional and structural characterization of the prp3 binding domain of the yeast prp4 splicing factorL Ayadi
Centre de Génétique Moléculaire du CNRS, Laboratoire Propre Associé à l Université P and M Curie, Gif sur Yvette, 91198, France
J Mol Biol 284:673-87. 1998..This surface could be used as a scaffold for generating an RNA-protein complex... - Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segmentJ Pastorek
Institute of Virology, Slovak Academy of Sciences, Bratislava
Oncogene 9:2877-88. 1994..In addition, the analysis of biological consequences of MN expression of NIH3T3 cells provides the evidence in favour of MN protein involvement in control of cell proliferation and transformation... - Domain-specific interactions of human HP1-type chromodomain proteins and inner nuclear membrane protein LBRQ Ye
Department of Medicine, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA
J Biol Chem 272:14983-9. 1997..The modular domain organization of HP1-type proteins and LBR can explain some of the diverse protein-protein interactions at the chromatin-lamina-membrane interface of the nuclear envelope... - Kx, a quantitatively minor protein from human erythrocytes, is palmitoylated in vivoF Carbonnet
Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, Paris, 75015, France
Biochem Biophys Res Commun 250:569-74. 1998..Palmitoylation of one or several of these cysteines might contribute to anchor the cytoplasmic portion of the Kx protein to the inner surface of red cell membrane... - The characterization of murine BCMA gene defines it as a new member of the tumor necrosis factor receptor superfamilyC Madry
INSERM CJF 95 02, Faculte de Medecine Paris Sud, Universite Paris XI, Clamart, France
Int Immunol 10:1693-702. 1998..Human BCMA is the first member of the TNFR family to be implicated in a chromosomal translocation... - Mutation in bone morphogenetic protein receptor-IB is associated with increased ovulation rate in Booroola Mérino ewesP Mulsant
Institut National de la Recherche Agronomique, Laboratoire de Genetique Cellulaire, BP, 27, 31326 Castanet Tolosan, France
Proc Natl Acad Sci U S A 98:5104-9. 2001..It is suggested that in FecB(B)/FecB(B) ewes, BMPR-IB would be inactivated partially, leading to an advanced differentiation of granulosa cells and an advanced maturation of ovulatory follicles... - Binding sites of leukocyte beta 2 integrins (LFA-1, Mac-1) on the human ICAM-4/LW blood group proteinP Hermand
INSERM U76, Institut National de la Transfusion Sanguine, 6 rue Alexandre Cabanel, 75015 Paris, France
J Biol Chem 275:26002-10. 2000..These data suggest that the binding site for LFA-1 on ICAM-4 overlaps but is distinct from the Mac-1 binding site... - A new subfamily of high molecular mass CDC2-related kinases with PITAI/VRE motifsF Marques
Laboratoire Arago, CNRS UMR 7628 Université Paris VI, BP 44, Banyuls sur mer Cedex, F 66651, France
Biochem Biophys Res Commun 279:832-7. 2000..CDC2L5 overexpressed in mammalian cells is an approximately 170-kDa nuclear protein. The mRNA is present during the sea urchin early embryogenesis and is ubiquitously expressed in human tissues... - Polydom: a secreted protein with pentraxin, complement control protein, epidermal growth factor and von Willebrand factor A domainsD Gilges
INSERM U474, Maternite Port Royal, 123 Bld de Port Royal 75014 Paris, France
Biochem J 352:49-59. 2000..The particular multidomain structure of the encoded protein suggests an important biological role in cellular adhesion and/or in the immune system...