Research Topics
| Didier CalavasSummaryCountry: France Publications
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Detail Information
Publications
Quantitative estimation of genetic risk for atypical scrapie in French sheep and potential consequences of the current breeding programme for resistance to scrapie on the risk of atypical scrapieAlexandre Fediaevsky
INRA, Centre de Clermont Theix, 63122 Saint Genes Champanelle, France
Genet Sel Evol 42:14. 2010....
Complementary approach of data analysis and modeling to estimate the pattern of the BSE epidemic: the example of FranceDidier Calavas
AFSSA, Epidemiology Unit, Lyon, France
Risk Anal 27:1141-50. 2007..We have waited up to June 2007 to know if less than 100 infections occurred among French cattle during the 6 months following January 2001...
Past, present and future of bovine spongiform encephalopathy in FranceD Calavas
Unité Epidémiologie, AFSSA Lyon, 31 av Tony Garnier, 69364, Lyon 07, France
Curr Top Microbiol Immunol 284:51-63. 2004..The trends in the number of BSE cases detected in France must be analyzed in the light of both the detection system and the control measures, as well as their changes over time...
Assessment of the utility of routinely collected cattle census and disposal data for syndromic surveillanceJean Baptiste Perrin
Unité Epidémiologie, Agence Nationale de Sécurité Sanitaire de l Alimentation, de l Environnement et du Travail ANSES, 31, Avenue Tony Garnier, F69364 Lyon cedex 07, France
Prev Vet Med 105:244-52. 2012....
Modelling the trend of bovine spongiform encephalopathy prevalence in France: Use of restricted cubic spline regression in age-period-cohort models to estimate the efficiency of control measuresCarole Sala
AFSSA Lyon, 31 avenue Tony Garnier, 69364 Lyon Cedex 7, France
Prev Vet Med 90:90-101. 2009....
Molecular typing of protease-resistant prion protein in transmissible spongiform encephalopathies of small ruminants, France, 2002-2009Johann Vulin
Agence Nationale de Sécurité Sanitaire, Lyon, France
Emerg Infect Dis 17:55-63. 2011....
Case-control study on feed risk factors for BSE cases born after the feed ban in FranceNathalie Jarrige
Unité Epidémiologie, AFSSA Lyon, 31 avenue Tony Garnier, 69364 Lyon Cedex 07, France
Vet Res 38:505-16. 2007..8 (1.1; 3.0). The use of milk replacers, which often incorporates animal fats, was also at risk with an odds ratio of 1.8 (1.0; 3.1)...
A case-control study on the origin of atypical scrapie in sheep, FranceAlexandre Fediaevsky
Agence Francaise de Securite Sanitaire des Aliments, Lyon, France
Emerg Infect Dis 15:710-8. 2009..We did not find any risk factor associated with an infectious origin of scrapie. Atypical scrapie could be a spontaneous disease influenced by genetic and metabolic factors...
Scrapie strain transmission studies in ovine PrP transgenic mice reveal dissimilar susceptibilityAnna Bencsik
ATNC unit, Agence Française de Sécurité Sanitaire des Aliments AFSSA, 31 avenue Tony Garnier, 69364, Lyon Cedex 07, France
Histochem Cell Biol 127:531-9. 2007....
Discrepant epidemiological patterns between classical and atypical scrapie in sheep flocks under French TSE control measuresAlexandre Fediaevsky
Agence Francaise de Securite Sanitaire des Aliments, Unité Epidémiologie, Lyon Cedex 07, France
Vet J 185:338-40. 2010....
Atypical bovine spongiform encephalopathies, France, 2001-2007Anne Gaelle Biacabe
Agence Francaise de Securite Sanitaire des Aliments, Lyon, France
Emerg Infect Dis 14:298-300. 2008..6 million were >8 years of age. Our retrospective Western blot study of all 645 confirmed cases found that 7 were H-type and 6 were L-type...
Sheep feed and scrapie, FranceSandrine Philippe
, Lyon, France
Emerg Infect Dis 11:1274-9. 2005..A notable effect of using proprietary concentrates and milk replacers was observed. The risk was heterogeneous among feed factories. Contacts between flocks were not shown to be a risk factor...
Using the National Cattle Register to estimate the excess mortality during an epidemic: application to an outbreak of Bluetongue serotype 8Jean Baptiste Perrin
Epidemiology Unit, French Agency for Food, Environmental and Occupational Health and Safety Anses, 31, Avenue Tony Garnier, F69364 Lyon cedex 07, France
Epidemics 2:207-14. 2010..This study was conducted retrospectively but considering the promptness of the notification system, the method could be used to monitor the evolution of epidemics in near-real time...
Distribution and antimicrobial resistance of clinical and subclinical mastitis pathogens in dairy cows in Rhône-Alpes, FranceMarie Anne Botrel
Agence Francaise de Securite Sanitaire des Aliments, Lyon, France
Foodborne Pathog Dis 7:479-87. 2010..However, it also confirms the fact that attention must be maintained to avoid any emergence of such resistant bacteria...
Comparison of strategies for substantiating freedom from scrapie in a sheep flockBenoit Durand
Unite d Epidemiologie, AFSSA LERPAZ, 23 Avenue du Général de Gaulle, 94706 Maisons Alfort, France
BMC Vet Res 5:16. 2009..The goal of this study was to propose, evaluate and compare several qualification strategies for demonstrating a flock is free from scrapie...
Automatic quantitation of vacuolar lesions in the brain of mice infected with transmissible spongiform encephalopathiesAnna Bencsik
Agence Française de Sécurité Sanitaire des Aliments AFSSA, Unité ATNC, 31 avenue Tony Garnier, 69364 Lyon Cedex 07, France
J Virol Methods 124:197-202. 2005..The method of automatic recognition and quantitation of vacuolar lesions described in this paper represent a useful tool for large-scale analysis of spongiform lesions induced by different TSE isolates transmitted to mice...
Individual factors associated with L- and H-type Bovine Spongiform encephalopathy in FranceCarole Sala
Anses Lyon, 31 avenue Tony Garnier, Lyon cedex 7, 69364, France
BMC Vet Res 8:74. 2012..L-BSE and H-BSE were studied separately as both the biochemical properties of their pathological prion protein and their features differ in animal models...
A descriptive study of the prevalence of atypical and classical scrapie in sheep in 20 European countriesAlexandre Fediaevsky
AFSSA Lyon, Unité Epidémiologie, 31 avenue Tony Garnier, 69364 Lyon Cedex 07, France
BMC Vet Res 4:19. 2008....
Molecular analysis of the protease-resistant prion protein in scrapie and bovine spongiform encephalopathy transmitted to ovine transgenic and wild-type miceThierry Baron
Unité Agents Transmissibles Non Conventionnels, AFSSA Lyon, 31 avenue Tony Garnier, 69364 Lyon Cedex 07, France
J Virol 78:6243-51. 2004....
Review on the epidemiology and dynamics of BSE epidemicsChristian Ducrot
INRA Unité d Epidémiologie Animale, 63122 Saint Genes Champanelle, France
Vet Res 39:15. 2008..The origin and possibility of natural transmission is unknown...
How the surveillance system may bias the results of analytical epidemiological studies on BSE: prevalence among dairy versus beef suckler cattle breeds in FranceChristian Ducrot
Unité d Epidémiologie Animale, INRA Theix, 63122 Saint Genes Champanelle, France
Vet Res 34:185-92. 2003..This confirmed British findings but points out to the fact that considering either MRS or targeted surveillance data alone may possibly create biases in epidemiological studies on BSE...
Temporal and spatial patterns of the clinical surveillance of BSE in France, analysed from January 1991 to May 2002 through a vigilance indexMarie Cuenot
, INRA Theix, , France
Vet Res 34:261-72. 2003..So the apparent trend in the BSE epidemic during this period as well as the differences in the spatial incidence of BSE have to be analysed with caution...
Descriptive spatial analysis of BSE in western FranceDavid Abrial
Unité d Epidémiologie Animale, INRA Theix, 63122 Saint Genes Champanelle, France
Vet Res 34:749-60. 2003..The results proved that the risk of BSE is linked to the geographical location in the area of the study...
Estimating the trend of the French BSE epidemic over six birth cohorts through the analysis of abattoir screening in 2001 and 2002Claude La Bonnardière
Unité d Epidémiologie Animale, INRA Theix, 63122 Saint Genes Champanelle, France Unité de Virologie et Immunologie Moléculaires, INRA, Domaine de Vilvert, 78352 Jouy en Josas Cedex, France
Vet Res 35:299-308. 2004....
Spatial heterogeneity of the risk of BSE in France following the ban of meat and bone meal in cattle feedDavid Abrial
Unité d Epidémiologie Animale, INRA, Centre de Recherche de Clermont Ferrand Theix, 63122 Saint Genes Champanelle, France
Prev Vet Med 67:69-82. 2005..The BSE cases were not randomly distributed. Furthermore, the areas at risk for the 'super-NAIF' matched part of the areas at risk for the 'NAIF' cases-which suggests that it might be a common source of contamination...
Poultry, pig and the risk of BSE following the feed ban in France--a spatial analysisDavid Abrial
Unité d Epidémiologie Animale, INRA Theix, 63122 Saint Genes Champanelle, France
Vet Res 36:615-28. 2005..Further studies are needed to more precisely explore how the cross-contamination happened...
A spatio-temporal analysis of BSE cases born before and after the reinforced feed ban in FranceChristian Ducrot
Unité d Epidémiologie Animale, INRA Theix, 63122 Saint Genes Champanelle, France
Vet Res 36:839-53. 2005....
PrP(d) accumulation in organs of ARQ/ARQ sheep experimentally infected with BSE by peripheral routesStephane Lezmi
Agence Française de Sécurité Sanitaire des Aliments AFSSA, Lyon Cedex 07, France
Acta Biochim Pol 53:399-405. 2006..Remarkably, PrP(d) was also detected in some muscle types as well as in all peripheral nerves that had not been reported previously thus revealing a widespread distribution of BSE-associated PrP(d) in sheep tissues...
Bovine spongiform encephalopathy and spatial analysis of the feed industryMathilde Paul
Institut National de la Recherche Agronomique, Saint Genes Champanelle, France
Emerg Infect Dis 13:867-71. 2007..Only use of MBM was spatially linked to risk for BSE, which highlights cross-contamination as the most probable source of infection after the feed ban...
Multiplicative genetic effects in scrapie disease susceptibilityMarc Antoine Dubois
SPEC, CEN Saclay, Orme des Merisiers, 91191 Gif sur Yvette, France
C R Biol 325:565-70. 2002..This first well-documented evidence of a multiplicative property of genetic risk factors could give hints on the underlying mechanisms of prion-induced neurodegenerative diseases...
