P Cacoub

Summary

Country: France

Publications

  1. pmc Meta-analyses of FibroTest diagnostic value in chronic liver disease
    Thierry Poynard
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Universite Paris VI, CNRS ESA 8067 Paris, France
    BMC Gastroenterol 7:40. 2007
  2. ncbi request reprint Transfusion-associated TT virus co-infection in patients with hepatitis C virus is associated with type II mixed cryoglobulinemia but not with B-cell non-Hodgkin lymphoma
    P Cacoub
    Service de Medecine Interne, CHU Pitie Salpetriere, Paris, France
    Clin Microbiol Infect 9:39-44. 2003
  3. ncbi request reprint [Collagenous colitis. A study of 11 cases]
    P Cacoub
    Service de Medecine Interne, GH Pitié Salpétrière, 75651 Paris Cedex 13
    Ann Med Interne (Paris) 152:299-303. 2001
  4. ncbi request reprint Deflazacort versus prednisone in patients with giant cell arteritis: effects on bone mass loss
    P Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Paris, France
    J Rheumatol 28:2474-9. 2001
  5. ncbi request reprint Cryoglobulinemia vasculitis
    Patrice Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Paris, France
    Curr Opin Rheumatol 14:29-35. 2002
  6. ncbi request reprint Hepatitis C virus infection and mixed cryoglobulinaemia vasculitis: a review of neurological complications
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 19:S128-34. 2005
  7. ncbi request reprint Hepatitis B virus genotypes and extrahepatic manifestations
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    J Hepatol 43:764-70. 2005
  8. ncbi request reprint Treatment of hepatitis C virus and human immunodeficiency virus coinfection: from large trials to real life
    P Cacoub
    Service de Médecine Interne and CNRS UMR 7087, Hopital de la Pitie, Paris, France
    J Viral Hepat 13:678-82. 2006
  9. pmc Management of chronic hepatitis C in French departments of internal medicine and infectious diseases
    P Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651, Paris, France
    Epidemiol Infect 133:305-14. 2005
  10. ncbi request reprint Impact of treatment on extra hepatic manifestations in patients with chronic hepatitis C
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    J Hepatol 36:812-8. 2002

Collaborators

Detail Information

Publications153 found, 100 shown here

  1. pmc Meta-analyses of FibroTest diagnostic value in chronic liver disease
    Thierry Poynard
    Service d Hepato Gastroenterologie, Groupe Hospitalier Pitie Salpetriere, Universite Paris VI, CNRS ESA 8067 Paris, France
    BMC Gastroenterol 7:40. 2007
    ....
  2. ncbi request reprint Transfusion-associated TT virus co-infection in patients with hepatitis C virus is associated with type II mixed cryoglobulinemia but not with B-cell non-Hodgkin lymphoma
    P Cacoub
    Service de Medecine Interne, CHU Pitie Salpetriere, Paris, France
    Clin Microbiol Infect 9:39-44. 2003
    ....
  3. ncbi request reprint [Collagenous colitis. A study of 11 cases]
    P Cacoub
    Service de Medecine Interne, GH Pitié Salpétrière, 75651 Paris Cedex 13
    Ann Med Interne (Paris) 152:299-303. 2001
    ..The aim of this retrospective study was to analyze extra-digestive manifestations of CC, associated systemic diseases, clinical course and response to therapeutic regimens...
  4. ncbi request reprint Deflazacort versus prednisone in patients with giant cell arteritis: effects on bone mass loss
    P Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Paris, France
    J Rheumatol 28:2474-9. 2001
    ..To compare bone mass loss due to deflazacort versus prednisone in longterm treatment of patients with giant cell arteritis (GCA) in a randomized double blind comparative trial...
  5. ncbi request reprint Cryoglobulinemia vasculitis
    Patrice Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Paris, France
    Curr Opin Rheumatol 14:29-35. 2002
    ....
  6. ncbi request reprint Hepatitis C virus infection and mixed cryoglobulinaemia vasculitis: a review of neurological complications
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 19:S128-34. 2005
    ..Central nervous system (CNS) involvement is more rarely reported. In this review, peripheral and CNS involvement associated with chronic HCV infection are described. The underlying mechanisms and treatment possibilities are discussed...
  7. ncbi request reprint Hepatitis B virus genotypes and extrahepatic manifestations
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    J Hepatol 43:764-70. 2005
    ..This study aimed at correlating the presence of extrahepatic manifestations with hepatitis B virus (HBV) genotypes in patients with chronic HBV infection...
  8. ncbi request reprint Treatment of hepatitis C virus and human immunodeficiency virus coinfection: from large trials to real life
    P Cacoub
    Service de Médecine Interne and CNRS UMR 7087, Hopital de la Pitie, Paris, France
    J Viral Hepat 13:678-82. 2006
    ..The main reasons are a treatment that may be deemed questionable (minimal hepatic lesions, alcohol, active drug use), a lack of available liver biopsy, a psychiatric contraindication and physician conviction of poor patient compliance...
  9. pmc Management of chronic hepatitis C in French departments of internal medicine and infectious diseases
    P Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651, Paris, France
    Epidemiol Infect 133:305-14. 2005
    ..Nevertheless, means of increasing the availability of antiviral therapies, particularly for patients with HIV co-infection or injecting drug use, require further study...
  10. ncbi request reprint Impact of treatment on extra hepatic manifestations in patients with chronic hepatitis C
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    J Hepatol 36:812-8. 2002
    ..The aim was to assess the prevalence of these symptoms prior to any treatment, and on prolonged follow-up in treated and untreated patients...
  11. ncbi request reprint PEGylated interferon alfa-2b and ribavirin treatment in patients with hepatitis C virus-related systemic vasculitis
    Patrice Cacoub
    hôpital La Pitié Salpêtrière, Paris, France
    Arthritis Rheum 52:911-5. 2005
    ..The present trial was established to investigate the efficacy of therapy with PEGylated interferon alfa-2b (PEG-IFN alfa-2b) plus ribavirin in patients with HCV-related MC vasculitis...
  12. ncbi request reprint Interferon-alpha and ribavirin treatment in patients with hepatitis C virus-related systemic vasculitis
    Patrice Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    Arthritis Rheum 46:3317-26. 2002
    ..Therefore, we retrospectively analyzed the response to treatment in patients with chronic hepatitis C complicated by systemic vasculitis who had received antiviral therapy with interferon-alpha (IFNalpha) and ribavirin...
  13. ncbi request reprint [Role of interferons in the treatment of hepatitis B and hepatitis C virus infections]
    P Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, 83, Boulevard de l Hopital, 75651 Paris, France
    Rev Med Interne 23:459s-474s. 2002
    ....
  14. ncbi request reprint Mortality among human immunodeficiency virus-infected patients with cirrhosis or hepatocellular carcinoma due to hepatitis C virus in French Departments of Internal Medicine/Infectious Diseases, in 1995 and 1997
    P Cacoub
    Dept of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    Clin Infect Dis 32:1207-14. 2001
    ..001) but not in HCV-related mortality rates (0.06% vs. 0.07%; P=.79). In France, despite the high prevalence of HCV infection in HIV-positive patients, the mortality rate in 1995 and 1997 caused by HCV-related cirrhosis or HCC was low...
  15. ncbi request reprint [Polymyositis induced by tiopronine]
    P Cacoub
    Service de Medecine Interne, CHU Pitie Salpetriere, Paris
    Presse Med 28:911-2. 1999
    ..D-penicillamine-induced muscle disorders are well-known, tiopronine-induced disorders are less often reported...
  16. ncbi request reprint Anti-endothelial cell auto-antibodies in hepatitis C virus mixed cryoglobulinemia
    P Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    J Hepatol 31:598-603. 1999
    ..The aim of the study was to determine the prevalence of AECA in HCV patients with or without MC-associated vasculitis, and to identify associations with clinical, immunological, virological and liver characteristics...
  17. ncbi request reprint [Severe gastrointestinal hemorrhage secondary to diffuse angiodysplasia: efficacy of estrogen-progesterone treatment]
    P Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Paris
    Presse Med 29:139-41. 2000
    ..Vascular abnormalities are being reported with increasing frequency as a cause of major lower gastrointestinal hemorrhage in the elderly. They are occasionally very difficult to treat by conventional means...
  18. ncbi request reprint Effect of cryopreservation on endothelin-1 productions of human mammary artery
    P Cacoub
    Service de Medecine Interne, Groupe Hospitalier Pitie Salpetriere, 75651, Paris, France
    Thromb Res 97:451-5. 2000
    ..However, the particularly high ET-1 concentration without associated cGMP concentration may be deleterious by increasing smooth-muscle cell proliferation and vascular tone of cryopreserved arteries...
  19. ncbi request reprint Mixed cryoglobulinemia in hepatitis C patients. GERMIVIC
    P Cacoub
    Service de Medecine Interne, Hopital Pitie Salpetriere, Paris
    Ann Med Interne (Paris) 151:20-9. 2000
    ....
  20. ncbi request reprint [Spinal cord involvement revealing systemic sarcoidosis]
    P Cacoub
    Service de Medecine Interne, La Pitié Salpêtrière, Paris
    Rev Neurol (Paris) 156:896-900. 2000
    ..Most patients with neurosarcoidosis have associated extraneurologic abnormalities. The diagnosis is supported usually by extraneurologic biopsies. Spinal cord biopsy needs to be considered on case-by-case basis...
  21. ncbi request reprint A new approach for rapid detection and typing of serum monoclonal components
    P Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Cedex 13, Paris, France
    Clin Chim Acta 302:105-24. 2000
    ..PPPM allows MC detection with great sensitivity. The immune protein profile dramatically increases the sensitivity of either SPE and/or KLR in detecting MC and may also allow heavy and light chain typing...
  22. ncbi request reprint [Edematous syndrome revealing an exudative lymphocytic gastritis: efficacy of omeprazole]
    P Cacoub
    Service de Medecine Interne, Hopital de la Pitie Salpetriere, Paris
    Gastroenterol Clin Biol 24:963-4. 2000
    ..Inflammatory involvement of the gastric mucosa probably caused protein losing in this patient. Recognition of this exsudative gastropathy is important because long term remission is obtained with omeprazole...
  23. ncbi request reprint Amyloidosis and cardiac involvement
    P Cacoub
    Department of Internal Medicine, La Pitie Hospital, Paris
    Ann Med Interne (Paris) 151:611-7. 2000
    ..Cardiac involvement may occur with or without clinical manifestations, and is considered as a major prognostic factor...
  24. ncbi request reprint Systemic vasculitis in patients with hepatitis C
    P Cacoub
    Department of Internal Medicine, H pital La Pitié Salpêtrière, Paris, France
    J Rheumatol 28:109-18. 2001
    ..To analyze the main characteristics of patients infected with hepatitis C virus (HCV) presenting with different types of vasculitis syndrome...
  25. doi request reprint Persistently normal alanine aminotransferase levels in HIV/HCV-coinfected patients: the role of steatosis
    F Bani-Sadr
    Groupe Hospitalier Universitaire Est, INSERM U 707, Universite Pierre et Marie Curie, Paris, France
    HIV Med 10:417-21. 2009
    ..We analysed factors associated with persistently normal ALT levels, defined as at least three consecutive normal ALT values over a 6-month period, in a group of 381 HIV/HCV-coinfected patients...
  26. ncbi request reprint Extrahepatic manifestations associated with hepatitis C virus infection. A prospective multicenter study of 321 patients. The GERMIVIC. Groupe d'Etude et de Recherche en Medecine Interne et Maladies Infectieuses sur le Virus de l'Hepatite C
    P Cacoub
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    Medicine (Baltimore) 79:47-56. 2000
    ..Cryoglobulin positivity is associated with systemic vasculitis and rheumatoid factor and HIV positivity. HIV coinfection is associated with arthralgia or myalgia, anticardiolipin antibodies, and thrombocytopenia...
  27. pmc Anti-C1q antibodies in hepatitis C virus infection
    D Saadoun
    Service de Medecine Interne, Hopital Pitie Salpetriere, 83 Boulevard de l hopital, 75651 Cedex 13 Paris, France
    Clin Exp Immunol 145:308-12. 2006
    ..Anti-C1q antibodies were associated with low C4 levels. No association was found between anti-C1q antibodies and HCV-MC vasculitis, nor between anti-C1q antibodies and cryoglobulinaemia...
  28. doi request reprint [Catastrophic antiphospholipid syndrome]
    N Costedoat-Chalumeau
    Service de Medecine Interne, Centre de Référence National pour le Lupus Systémique et le Syndrome des Antiphospholipides, faculté Paris 6, Hopital Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Rev Med Interne 33:194-9. 2012
    ..The prevention of CAPS is based upon the adequate management of the perioperative period when surgery cannot be avoided, the prompt treatment of infections and the education of patients with antiphospholipid syndrome...
  29. ncbi request reprint Hepatitis C virus infection and lymphoproliferative diseases: prospective study on 1,576 patients in France
    P Hausfater
    Service de Medecine Interne, CHU Pitie Salpetriere, 83 87 Boulevard de l Hôpital, Paris, France
    Am J Hematol 67:168-71. 2001
    ..Discordant data have been reported about the prevalence of hepatitis C virus (HCV) infection in patients with lymphoproliferative diseases and the putative role of HCV in lymphomagenesis...
  30. doi request reprint Peripheral arterial disease and isolated systolic hypertension: the ATTEST study
    M E Safar
    Faculte de Medecine, Hotel Dieu Hospital, Universite Paris Descartes, Paris, France
    J Hum Hypertens 23:182-7. 2009
    ..Finally, one of the predominant goals of secondary prevention in subjects with PAD should be the treatment of isolated systolic hypertension...
  31. ncbi request reprint Severe weight loss in HIV / HCV-coinfected patients treated with interferon plus ribavirin: incidence and risk factors
    F Bani-Sadr
    Groupe Hospitalier Universitaire Est, Universite Paris 6, INSERM U707, Paris, France
    J Viral Hepat 15:255-60. 2008
    ..These findings show that severe weight loss is a frequent side effect of anti-HCV therapy in HIV / HCV-coinfected patients. The underlying mechanisms remain to be identified...
  32. doi request reprint Immunosuppressants reduce venous thrombosis relapse in Behçet's disease
    A C Desbois
    UMR CNRS 7211, INSERM U959, Groupe Hospitalier Pitie Salpetriere, AP HP, and Université Pierre et Marie Curie Paris 6, Paris, France
    Arthritis Rheum 64:2753-60. 2012
    ..To investigate and describe the long-term outcome of venous thrombosis in patients with Behçet's disease (BD)...
  33. ncbi request reprint [Vitamin D and autoimmunity. Second part: Clinical aspects]
    Y Schoindre
    Service de Medecine Interne, Université Versailles Saint Quentin en Yvelines, Hopital Foch, 40, rue Worth, 92151 Suresnes Cedex, France
    Rev Med Interne 33:87-93. 2012
    ....
  34. ncbi request reprint Risk factors for anaemia in human immunodeficiency virus/hepatitis C virus-coinfected patients treated with interferon plus ribavirin
    F Bani-Sadr
    Groupe Hospitalier Universitaire Est, Universite Paris, INSERM U707, Paris, France
    J Viral Hepat 14:639-44. 2007
    ..26-0.49, P < 0.0001) and in patients receiving protease inhibitor-based antiretroviral therapy (OR, 0.51 95% CI, 0.30-0.86, P = 0.0114). Zidovudine discontinuation could help to avoid anaemia associated with anti-HCV therapy...
  35. doi request reprint Serum-free light chain assessment in hepatitis C virus-related lymphoproliferative disorders
    B Terrier
    Department of Internal Medicine, AP HP Groupe Hospitalier Pitié Salpétrière, Paris, France
    Ann Rheum Dis 68:89-93. 2009
    ..To evaluate the relevance of serum-free light chain (FLC) assessment in hepatitis C virus (HCV)-related lymphoproliferative disorders, including mixed cryoglobulinemia (MC) and B cell non-Hodgkin lymphoma (B-NHL)...
  36. ncbi request reprint Evolution of biomarkers of liver fibrosis and liver insufficiency in hepatitis C virus-infected patients treated with pegylated interferon plus ribavirin and rituximab
    G Geri
    Department of Internal Medicine, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France
    J Viral Hepat 19:497-500. 2012
    ..No beneficial effects of RTX were evidenced on liver fibrosis progression, but we found interesting correlations with the serum albumin level, FibroTest values and B-cell count...
  37. doi request reprint Hepatitis C virus-associated polyarteritis nodosa
    D Saadoun
    Assistance Publique Hopitaux de Paris, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Arthritis Care Res (Hoboken) 63:427-35. 2011
    ..To analyze the main characteristics and outcome of polyarteritis nodosa (PAN)-type vasculitis associated with hepatitis C virus (HCV)...
  38. doi request reprint Severe transaminitis after interferon-ribavirin therapy in HIV/HCV-coinfected patients: influence of a sustained HCV response
    F Bani-Sadr
    Groupe Hospitalier Universitaire Est, INSERM U 707, Universite Pierre et Marie Curie, UMR S 707, UPMC Paris 6, Paris, France
    J Viral Hepat 19:431-5. 2012
    ..Treatment of HCV infection should therefore be a priority in HIV-coinfected patients. Stavudine is associated with an increased risk of severe transaminitis...
  39. ncbi request reprint [Cryoglobulinemia]
    P Cacoub
    Service de Médecine Interne II, hôpital La Pitié Salpêtrière, AP HP, 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Rev Med Interne 29:200-8. 2008
    ..Cryoglobulin may be an isolated biological abnormality or may induce clinical manifestations of a systemic vasculitis, involving the skin, the joints, the peripheral nerve system and the kidneys...
  40. ncbi request reprint Lower expression of CD81 B-cell receptor in lymphoproliferative diseases associated with hepatitis C virus infection
    P Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Bd de l Hopital, Paris Cedex, France
    J Viral Hepat 10:10-5. 2003
    ..89, P = 0.02). In patients with a chronic active HCV infection, the presence of a lymphoproliferative disease, either MC or B-NHL, is associated with lower expression of CD81 and higher expression of CD19 receptor on peripheral B cells...
  41. doi request reprint Mortality in Behçet's disease
    D Saadoun
    Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, and Université Pierre et Marie Curie Paris 6, Paris, France
    Arthritis Rheum 62:2806-12. 2010
    ..To report the long-term mortality in patients with Behçet's disease (BD)...
  42. doi request reprint Cerebral venous thrombosis in Behçet's disease
    D Saadoun
    Hôpital Pitié Salpétrière and Pierre et Marie Curie Paris VI University, Paris, France
    Arthritis Rheum 61:518-26. 2009
    ..To analyze the clinical findings, treatment, outcome, and prevalence of cerebral venous thrombosis (CVT) in a large cohort of patients with Behçet's disease (BD) from a single center...
  43. doi request reprint [Cryofibrinogenemia]
    D Saadoun
    UMR 7211 Inserm U959, centre de références maladies auto immunes, Service de Médecine Interne II, Hopital Pitie Salpetriere, 75013 Paris, France
    Rev Med Interne 32:287-91. 2011
    ..In this article, we review the clinical presentation, pathogenesis and treatment of CF...
  44. pmc Patient education improves adherence to peg-interferon and ribavirin in chronic genotype 2 or 3 hepatitis C virus infection: a prospective, real-life, observational study
    Patrice Cacoub
    Department of Internal Medicine, Pitie Salpetriere Hospital, 47 83 boulevard de l Hopital, Paris cedex 13 F 75651, France
    World J Gastroenterol 14:6195-203. 2008
    ....
  45. ncbi request reprint Cryoglobulinemia is associated with steatosis and fibrosis in chronic hepatitis C
    David Saadoun
    Service de Médecine Interne and CNRS UMR 7087, Hopital Pitie Salpetriere, Paris, France
    Hepatology 43:1337-45. 2006
    ..001), and steatosis higher than 10% (P = .04). In conclusion, our study shows an independent association between cryoglobulin and steatosis as well as advanced fibrosis...
  46. pmc Anti-cyclic citrullinated peptide antibodies in hepatitis C virus associated rheumatological manifestations and Sjogren's syndrome
    D Sene
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    Ann Rheum Dis 65:394-7. 2006
    ..To investigate the diagnostic reliability of anti-CCP antibodies (anti-CCP Ab) in distinguishing hepatitis C virus (HCV) associated rheumatological manifestations and Sjögren's syndrome from rheumatoid arthritis...
  47. doi request reprint [Management of the risk of hepatitis B virus reactivation in patients receiving immunosuppressive and immunomodulatory agents in internal medicine: data from the REACTI-B survey and proposal for a management algorithm]
    B Terrier
    Service de Medecine Interne, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Rev Med Interne 33:4-12. 2012
    ....
  48. ncbi request reprint Natural history of HCV infection
    T Poynard
    Department of Internal Medicine, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Baillieres Best Pract Res Clin Gastroenterol 14:211-28. 2000
    ..In contrast severe extrahepatic manifestations are rare, with 1% for systemic vasculitis...
  49. ncbi request reprint Liver-related mortality in human-immunodeficiency-virus-infected patients between 1995 and 2003 in the French GERMIVIC Joint Study Group Network (MORTAVIC 2003 Study)
    E Rosenthal
    Department of Internal Medicine, hôpital de l Archet 1, Nice, France
    J Viral Hepat 14:183-8. 2007
    ..4%) than in 2001 (26.3%). Seven years after the introduction of HAART, ESLD associated with HCV infections is a leading cause of mortality in HIV-infected patients, which did not increase between the years 2001 and 2003...
  50. doi request reprint Liver-related deaths in HIV-infected patients between 1995 and 2005 in the French GERMIVIC Joint Study Group Network (Mortavic 2005 study in collaboration with the Mortalité 2005 survey, ANRS EN19)
    E Rosenthal
    Department of Internal Medicine, Archet Hospital Centre, University of Nice Sophia Antipolis, Nice, France
    HIV Med 10:282-9. 2009
    ..More than 10 years after the introduction of combination antiretroviral therapy (cART), we examined the trend in the proportion of deaths caused by end-stage liver disease (ESLD) in HIV-infected adults in France between 1995 and 2005...
  51. ncbi request reprint Fatigue in patients with chronic hepatitis C
    T Poynard
    Departments of Hepatogastroenterology, hôpital La Pitié Salpêtrière, Paris, France
    J Viral Hepat 9:295-303. 2002
    ..Hence, fatigue is the most frequent extrahepatic manifestation in patients infected with HCV. Fatigue is independently associated with female gender, age over 50 years, cirrhosis, depression and purpura...
  52. ncbi request reprint Hepatitis C virus-associated B-cell proliferation--the role of serum B lymphocyte stimulator (BLyS/BAFF)
    D Sene
    Department of Internal Medicine, La Pitié Salpêtrière, 83 Boulevard de l hopital, 75651 Paris Cedex 13, France
    Rheumatology (Oxford) 46:65-9. 2007
    ..We assessed BLyS serum levels in HCV-infected patients and in various forms of HCV-associated BCP [i.e. mixed cryoglobulin (MC), rheumatoid factor (RF) and systemic vasculitis]...
  53. pmc Hepatitis B virus-human immunodeficiency virus co-infection in France: a cross-sectional multicentre study
    D Sene
    hôpital La Pitié Salpêtrière, Service de Medecine Interne, Paris, France
    Epidemiol Infect 135:409-16. 2007
    ..45.7%, P<10(-4)), mainly lamivudine and tenofovir. Significant improvements in the management of such patients are awaited mainly in the appraisal of liver disease by either liver biopsy or non-invasive alternatives to liver biopsy...
  54. ncbi request reprint [Vitamin D and autoimmunity. First part: Fundamental aspects]
    Y Schoindre
    Service de Medecine Interne, Université Versailles Saint Quentin en Yvelines, Hopital Foch, 40, rue Worth, 92151 Suresnes Cedex, France
    Rev Med Interne 33:80-6. 2012
    ..The authors present their actions on myeloid dendritic cells, T cells, B cells, as well as on the synthesis of antimicrobial peptides and autophagy, and the potential beneficial effects in autoimmune and inflammatory diseases...
  55. ncbi request reprint ActiTest accuracy for the assessment of histological activity grades in patients with chronic hepatitis C, an overview using Obuchowski measure
    T Poynard
    UPMC Paris Liver Center, AP HP, Paris, France
    Gastroenterol Clin Biol 34:388-96. 2010
    ..ActiTest (AT) is a biomarker of liver necro-inflammatory histological activity validated in patients with chronic hepatitis C (HCV)...
  56. ncbi request reprint AL cardiac amyloidosis and arterial thromboembolic events
    P Hausfater
    Emergency Department, Pitie Salpetriere University Hospital Centre, 75651 Paris Cedex 13, France
    Scand J Rheumatol 34:315-9. 2005
    ..To study the prevalence and characteristics of arterial thromboembolic events (ATEE) in the course of AL amyloidosis...
  57. doi request reprint Azathioprine in severe uveitis of Behçet's disease
    D Saadoun
    Hôpital Pitié Salpétrière and Pierre et Marie Curie Paris VI University, Paris, France
    Arthritis Care Res (Hoboken) 62:1733-8. 2010
    ..To investigate the efficacy and tolerance of azathioprine in severe uveitis related to Behçet's disease (BD)...
  58. doi request reprint The B lymphocyte stimulator receptor-ligand system in hepatitis C virus-induced B cell clonal disorders
    D A Landau
    Laboratoire de Biologie et Thérapeutique des Pathologies Immunitaires, Centre National de la Recherche Sientifique, Universite Pierre et Marrie Curie UMR 7087, Paris, France
    Ann Rheum Dis 68:337-44. 2009
    ..The study aim was to examine the B lymphocyte stimulator (BLyS) receptor-ligand system in hepatitis C virus (HCV)-induced B lymphocyte clonal disorders...
  59. doi request reprint Antimyeloperoxidase antibodies are a useful marker of disease activity in antineutrophil cytoplasmic antibody-associated vasculitides
    B Terrier
    Department of Internal Medicine, Groupe Hospitalier Pitie Salpetriere, 47 Boulevard de l Hopital, 75013 Paris, France
    Ann Rheum Dis 68:1564-71. 2009
    ..To evaluate the relevance of monitoring antimyeloperoxidase antibody levels in the management of antimyeloperoxidase-associated vasculitides...
  60. ncbi request reprint Influence of antiviral therapy in hepatitis C virus-associated cryoglobulinemic MPGN
    Laurent Alric
    Service de Medecine Interne, Pavillon Dieulafoy, CHU Purpan, Toulouse, France
    Am J Kidney Dis 43:617-23. 2004
    ..The influence of hepatitis C virus (HCV) treatment on the course of HCV cryoglobulinemic membranoproliferative glomerulonephritis (MPGN) is controversial...
  61. ncbi request reprint [Treatment of extrahepatic manifestations associated with hepatitis C virus infection]
    Patrice Cacoub
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Paris
    Gastroenterol Clin Biol 26:B210-9. 2002
  62. doi request reprint Causes and predictive factors of mortality in a cohort of patients with hepatitis C virus-related cryoglobulinemic vasculitis treated with antiviral therapy
    Dan Avi Landau
    Service de Medecine Interne, AP HP, Hopital Pitie Salpetriere, Paris, France
    J Rheumatol 37:615-21. 2010
    ..We studied causes of death and predictive factors in patients with HCV-associated MC vasculitis treated with antivirals...
  63. ncbi request reprint Relapse of hepatitis C virus-associated mixed cryoglobulinemia vasculitis in patients with sustained viral response
    Dan Avi Landau
    Universite Pierre et Marie Curie Paris 6, CNRS, UMR 7087, Assistance Publique Hopitaux de Paris, Hopital Pitie Salpetriere, Paris, France
    Arthritis Rheum 58:604-11. 2008
    ....
  64. ncbi request reprint Treatment of hepatitis C virus in human immunodeficiency virus infected patients in "real life": modifications in two large surveys between 2004 and 2006
    Patrice Cacoub
    Universite Pierre et Marie Curie Paris 6, CNRS, UMR 7087, Paris, France
    J Hepatol 48:35-42. 2008
    ..To analyze the barriers to HCV treatment in HIV-HCV co-infected patients and their evolution between 2004 and 2006...
  65. ncbi request reprint Rituximab plus Peg-interferon-alpha/ribavirin compared with Peg-interferon-alpha/ribavirin in hepatitis C-related mixed cryoglobulinemia
    David Saadoun
    Department of Internal Medicine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Blood 116:326-34; quiz 504-5. 2010
    ..Our findings indicate that rituximab combined with Peg-IFN-alpha/ribavirin is well tolerated and more effective than Peg-IFN-alpha/ribavirin in HCV-MC...
  66. ncbi request reprint [Update in Hepatitis C virus associated extrahepatic manifestations]
    D Sene
    Service de Medecine Interne, Hopital de la Pitie Salpetriere, 91, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Rev Med Interne 28:388-93. 2007
    ..The use of anti-CD20 antibodies in the treatment of cryoglobulinemic vasculitis is also under investigation...
  67. doi request reprint Prevalence, characteristics and prognostic significance of anemia in daily practice
    B Terrier
    Department of Internal Medicine, APHP Groupe Hospitalier Pitié Salpé trière, Universite Pierre et Marie Curie, Paris 6, Paris, France
    QJM 105:345-54. 2012
    ..The prevalence of anemia has been studied in well-defined populations, but no large study is available for less restricted populations with various disorders...
  68. ncbi request reprint Subacute bacterial endocarditis presenting as polymyalgia rheumatica or giant cell arteritis
    C Auzary
    Department of Internal Medicine, Centre Hospitalier Moulins Yzeure, Moulins, France
    Clin Exp Rheumatol 24:S38-40. 2006
    ..To report on several patients with subacute bacterial endocarditis who were initially presumed, incorrectly, to have polymyalgia rheumatica or giant cell arteritis...
  69. ncbi request reprint [HIV and hepatitis C virus coinfection]
    P Cacoub
    Service de Medecine Interne, AP HP, hôpital La Pitié Salpêtrière, 83, Bd de l Hopital, 7 5651 Paris cedex 13, France
    Gastroenterol Clin Biol 32:S82-9. 2008
    ..Effective management strategies that encompass patient and viral factors are necessary to improve the long-term outlook for coinfected patients...
  70. doi request reprint Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database
    Christian Pagnoux
    Universite Paris Descartes, Hopital Cochin, Assistance Publique Hopitaux de Paris, Paris, France
    Arthritis Rheum 62:616-26. 2010
    ..This study was undertaken to describe the main characteristics of and long-term outcomes in patients with well-characterized PAN diagnoses...
  71. ncbi request reprint Influence of HLA-DR phenotype on the risk of hepatitis C virus-associated mixed cryoglobulinemia
    P Cacoub
    Department of Internal Medicine, , Paris, France
    Arthritis Rheum 44:2118-24. 2001
    ..In contrast, HLA-DR7 appears to protect against the production of type II MC. These results suggest that the host's immune response genes may play a role in the pathogenesis of HCV-associated MC...
  72. ncbi request reprint Postvaccine vasculitis: a report of three cases]
    D Saadoun
    , , 47-83, , 75651 Paris, France
    Rev Med Interne 22:172-6. 2001
    ....
  73. ncbi request reprint Genetic heterogeneity of the hypervariable region I of Hepatitis C virus and lymphoproliferative disorders
    A Rigolet
    Virology Laboratory, Hopital Pitie Salpetriere, 75651 Paris, France
    Leukemia 19:1070-6. 2005
    ..Contrary to recent findings, our analysis based on multiple clones per patient analysis did not reveal any particular motif associated with BCLD...
  74. ncbi request reprint Hepatitis C virus infection induced vasculitis
    Patrice Cacoub
    Universite Pierre et Marie Curie Paris 6, CNRS, UMR 7087, Paris, France
    Clin Rev Allergy Immunol 35:30-9. 2008
    ..For future prospects and projects, new therapeutic strategies include a combination of best antiviral treatment with Peg-Interferon plus Ribavirin and Rituximab. Multicenter controlled trials are mandatory...
  75. ncbi request reprint [Neurological manifestations in cryoglobulinemia]
    T Maisonobe
    Groupe Hospitalier Pitie Salpetriere, Service d Explorations Fonctionnelles Neurologie, France
    Rev Neurol (Paris) 158:920-4. 2002
    ..Prognostic and treatment depend on association with hepatitis C, and presence of vasculitis lesions in the nerve biopsy...
  76. ncbi request reprint Predominance of type 1 (Th1) cytokine production in the liver of patients with HCV-associated mixed cryoglobulinemia vasculitis
    David Saadoun
    Service de Medecine Interne, Hopital Pitie Salpetriere, 47 bd de l Hopital, 75013 Paris, France
    J Hepatol 41:1031-7. 2004
    ..To compare the cytokine profile of liver-infiltrating T cells in HCV-infected patients with or without MC vasculitis...
  77. ncbi request reprint Cryoglobulinaemia vasculitis in patients coinfected with HIV and hepatitis C virus
    David Saadoun
    Service de Medecine Interne, hôpital La Pitié Salpêtrière, Paris, France
    AIDS 20:871-7. 2006
    ..To describe mixed cryoglobulinaemia (MC) vasculitis in patients coinfected with hepatitis C virus (HCV) and HIV...
  78. ncbi request reprint Pegylated interferon alfa-2b vs standard interferon alfa-2b, plus ribavirin, for chronic hepatitis C in HIV-infected patients: a randomized controlled trial
    Fabrice Carrat
    Groupe Hospitalier Universitaire Est, Universite Paris 6, INSERM U444, Paris, France
    JAMA 292:2839-48. 2004
    ..Most data on the virologic efficacy and safety of the combination of peginterferon alfa-2b and ribavirin in coinfected patients come from uncontrolled studies...
  79. ncbi request reprint Correlation of clinical and virologic responses to antiviral treatment and regulatory T cell evolution in patients with hepatitis C virus-induced mixed cryoglobulinemia vasculitis
    Dan Avi Landau
    Universite Pierre et Marie Curie Paris 6, CNRS, UMR 7087, Paris, France
    Arthritis Rheum 58:2897-907. 2008
    ..The aim of this study was to prospectively evaluate the evolution of this defect during the course of antiviral treatment...
  80. doi request reprint The association of systemic lupus erythematosus and myasthenia gravis: a series of 17 cases, with a special focus on hydroxychloroquine use and a review of the literature
    M Jallouli
    Centre Hospitalier Universitaire Pitie Salpetriere, Universite Paris 6, AP HP, Paris, France
    J Neurol 259:1290-7. 2012
    ..Hydroxychloroquine treatment appears to be safe in this setting...
  81. doi request reprint Safety and efficacy of rituximab in nonviral cryoglobulinemia vasculitis: data from the French Autoimmunity and Rituximab registry
    B Terrier
    Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie Paris 6, Paris, France
    Arthritis Care Res (Hoboken) 62:1787-95. 2010
    ..Rituximab has emerged as a novel and promising therapeutic alternative, but data are scarce. Our objective was to evaluate the safety and efficacy of rituximab in nonviral cryoglobulinemia vasculitis in off-trial real-life patients...
  82. pmc Prevalence of peripheral arterial disease in high-risk patients using ankle-brachial index in general practice: a cross-sectional study
    P Cacoub
    Pierre et Marie Curie, Paris 6, University, Paris, France
    Int J Clin Pract 63:63-70. 2009
    ..We evaluated the prevalence and predictive factors of PAD in high-risk patients using the ankle-brachial index (ABI)...
  83. ncbi request reprint Neuro-Behçet's disease (isolated cerebral thrombophlebitis excluded). Clinical pattern, prognostic factors, treatment and long term follow-up
    A Sbai
    Pitie Salpetriere Hospital, Internal Medicine Department, Paris, France
    Adv Exp Med Biol 528:371-6. 2003
  84. ncbi request reprint Plasma exchange and interferon-alpha pharmacokinetics in patients with hepatitis C virus-associated systemic vasculitis
    P Hausfater
    Department of Internal Medicine, CHU Pitie Salpetriere, Paris, France
    Nephron 91:627-30. 2002
    ..Therapeutic approach of such severely symptomatic patients include interferon-alpha (IFN) plus plasma exchange (PE). There are no data on IFN pharmacokinetic changes related to PE...
  85. ncbi request reprint [Ocular manifestations of Behçet's disease]
    D Saadoun
    CNRS UMR 7087, Service de Medecine Interne, Hopital de la Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Rev Med Interne 31:545-50. 2010
    ..Controlled clinical trials are mandatory to define the place of these new immunomodulatory agents in the therapeutic strategy, and especially their use as first-line therapy...
  86. doi request reprint Treatment of hepatitis C-associated mixed cryoglobulinemia vasculitis
    David Saadoun
    Université Pierre et Marie Curie Paris, Paris, France and Hôpital Pitié Salpêtrière, Service de Medecine Interne, Paris, France
    Curr Opin Rheumatol 20:23-8. 2008
    ..This review focuses on recent advances in our understanding of the treatment of hepatitis C virus-mixed cryoglobulinemia vasculitis...
  87. doi request reprint Efficacy and tolerability of rituximab with or without PEGylated interferon alfa-2b plus ribavirin in severe hepatitis C virus-related vasculitis: a long-term followup study of thirty-two patients
    Benjamin Terrier
    Department of Internal Medicine, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris AP HP, CNRS UMR 7211, and Université Pierre et Marie Curie Paris 6, Paris, France
    Arthritis Rheum 60:2531-40. 2009
    ..To report on the long-term followup of a cohort of patients with hepatitis C virus (HCV)-related vasculitis treated with rituximab with or without PEGylated interferon alfa-2b (PEG-IFN alfa-2b) plus ribavirin...
  88. ncbi request reprint Antiviral therapy for hepatitis C virus--associated mixed cryoglobulinemia vasculitis: a long-term followup study
    David Saadoun
    hôpital La Pitié Salpêtrière, Paris, France
    Arthritis Rheum 54:3696-706. 2006
    ..To evaluate the long-term efficacy of anti-hepatitis C virus (HCV) therapy in patients with HCV-associated mixed cryoglobulinemia (HCV-MC) vasculitis and to assess the factors associated with clinical remission of MC...
  89. ncbi request reprint Long-term impact of renal transplantation on liver fibrosis during hepatitis C virus infection
    Laurent Alric
    Service de Medecine Interne, Pavillon Dieulafoy, CHU Purpan, Toulouse, France
    Gastroenterology 123:1494-9. 2002
    ....
  90. ncbi request reprint Insulin resistance impairs sustained virological response rate to pegylated interferon plus ribavirin in HIV-hepatitis C virus-coinfected patients: HOMAVIC-ANRS HC02 Study
    Patrice Cacoub
    Universite Pierre et Marie Curie Paris 6, CNRS, UMR 7087, Paris, France
    Antivir Ther 14:839-45. 2009
    ..The aim of this study was to assess the effect of insulin resistance (IR) on the response to hepatitis C virus (HCV) therapy in HIV-HCV-coinfected patients...
  91. ncbi request reprint Neurological complications of primary Sjögren's syndrome
    C Lafitte
    Fédération de Neurologie Mazarin, Hĵpital de la Salpêtrière, Paris, France
    J Neurol 248:577-84. 2001
    ..To better delineate the spectrum of neurological complications of primary Sjögren's syndrome (PSS)...
  92. ncbi request reprint Anti-CD20 monoclonal antibody (rituximab) treatment for cryoglobulinemic vasculitis: where do we stand?
    P Cacoub
    Universite Pierre et Marie Curie Paris 6, CNRS, UMR 7087, Paris, France
    Ann Rheum Dis 67:283-7. 2008
    ..A relapse of cryoglobulinemia vasculitis was frequently noted. Randomised controlled trials with long-term study are needed to form definitive conclusions on the benefit/risk ratio of rituximab therapy in such patients...
  93. ncbi request reprint Vogt-Koyanagi-Harada disease in patients with chronic hepatitis C
    Valerie Touitou
    Department of Ophthalmology, Pitie Salpetriere Hospital, Paris, France
    Am J Ophthalmol 140:949-52. 2005
    ..To report the cases of four patients with hepatitis C virus infection who experienced clinical features that are virtually identical to Vogt-Koyanagi-Harada disease (VKH)...
  94. ncbi request reprint Hepatitis C virus-associated extrahepatic manifestations: a review
    Damien Sene
    Department of Internal Medicine, Boulevard de l Hopital, Paris, France
    Metab Brain Dis 19:357-81. 2004
    ..Howerver, even in cases of tight association, the mechanisms through which HCV may promote or induce extrahepatic manifestations remain unclear and merit further investigations...
  95. ncbi request reprint [Management of HCV-HIV and HBV-HIV coinfected patients]
    Patrice Cacoub
    Universite Pierre et Marie Curie, Paris 6, CNRS, UMR 7087, Paris, France
    Gastroenterol Clin Biol 31:887-94. 2007
  96. pmc Intraocular complications of IFN-alpha and ribavirin therapy in patients with chronic viral hepatitis C
    Damien Sene
    Department of Internal Medicine, Hopital Pitie Salpetriere, Paris, France
    World J Gastroenterol 13:3137-40. 2007
    ..Rare as they are, such severe ophthalmological complications require a close follow-up of HCV-infected patients under IFN-alpha treatment with ophthalmological monitoring if any ocular manifestation occurs...
  97. ncbi request reprint Longterm course of mixed cryoglobulinemia in patients infected with hepatitis C virus
    Damien Sene
    Department of Internal Medicine, hôpital La Pitié Salpêtrière, Paris, France
    J Rheumatol 31:2199-206. 2004
    ..To describe epidemiological, clinical, and immunological characteristics and the longterm course of persistent mixed cryoglobulinemia (MC) in patients infected with hepatitis C virus (HCV)...
  98. doi request reprint Cryofibrinogen in patients with hepatitis C virus infection
    Aurelien Delluc
    Service de Medecine Interne, Universite Pierre et Marie Curie, Paris 6, France
    Am J Med 121:624-31. 2008
    ..The objective was to study the prevalence and the clinical and therapeutic impacts of cryofibrinogen in HCV-infected patients...
  99. ncbi request reprint Testing for anti-nucleosome antibodies in daily practice: a monocentric evaluation in 1696 patients
    P Ghillani-Dalbin
    Service d Immunochimie, Hopital Pitie Salpetriere, Paris, France
    Lupus 12:833-7. 2003
    ..In conclusion, this study extends the relevance of anti-Nuc Ab to routine use for the diagnosis of connective tissue diseases, mainly anti-dsDNA Ab negative SLE...
  100. ncbi request reprint Regression of splenic lymphoma with villous lymphocytes after treatment of hepatitis C virus infection
    Olivier Hermine
    Department of Hematology and Centre National de la Recherche Scientifique Unité Mixte de Recherche 8603, Hopital Necker, Paris, France
    N Engl J Med 347:89-94. 2002
    ..We undertook this study after a patient with splenic lymphoma with villous lymphocytes had a hematologic response after antiviral treatment of HCV infection...
  101. ncbi request reprint Spontaneous hepatic decompensation in patients coinfected with HIV and hepatitis C virus during interferon-ribavirin combination treatment
    Firouzé Bani-Sadr
    INSERM U707, Faculte de Medecine Hopital Saint Antoine, Paris, France
    Clin Infect Dis 41:1806-9. 2005
    ..02), and elevated total bilirubin level (OR, 7.9; 95% CI, 1.08-93.3; P<.03). Didanosine should thus not be given to patients with cirrhosis, particularly when treatments for HCV and HIV infections have to be administered concomitantly...