Francis Brunelle

Summary

Country: France

Publications

  1. ncbi request reprint 1H MRS spectroscopy evidence of cerebellar high lactate in mitochondrial respiratory chain deficiency
    N Boddaert
    Service de Radiologie Pediatrique, U797, Hopital Necker Enfants Malades, 149 rue de Sevres, Paris, France
    Mol Genet Metab 93:85-8. 2008
  2. ncbi request reprint Brain vascular malformations in the fetus: diagnosis and prognosis
    Francis Brunelle
    Pediatric Radiology, Groupe Hospitalier Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Childs Nerv Syst 19:524-8. 2003
  3. ncbi request reprint Fetal CT
    Francis Brunelle
    Service de Radiologie Pediatrique, Groupe Hospitalier Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Childs Nerv Syst 19:415-7. 2003
  4. ncbi request reprint Noninvasive diagnosis of brain tumours in children
    F Brunelle
    Hopital des Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    Childs Nerv Syst 16:731-4. 2000
  5. ncbi request reprint Congenital hyperinsulinism: pancreatic [18F]fluoro-L-dihydroxyphenylalanine (DOPA) positron emission tomography and immunohistochemistry study of DOPA decarboxylase and insulin secretion
    Pascale de Lonlay
    Departement de Pediatrie, Hopital Necker Enfants Malades, Universite Paris Descartes, Faculte de Medecine, 149 rue de Sevres, 75743 Paris Cedex 15, France
    J Clin Endocrinol Metab 91:933-40. 2006
  6. doi request reprint Value of 18F-fluoro-L-dopa PET in the preoperative localization of focal lesions in congenital hyperinsulinism
    Carmen Capito
    Departments of Pediatric Surgery, Radiology, Pathology, and Pediatrics, Necker Enfants Malades Hospital, AP HP, 75015 Paris, France
    Radiology 253:216-22. 2009
  7. ncbi request reprint [MRI and fetal multidetector CT in the diagnosis of fetal malformations]
    Francis Brunelle
    Radiologie Pédiatrique, Hopital des Enfants Malades, 147, rue de Sevres, 75743 Paris Cedex 15
    Bull Acad Natl Med 192:1559-73; discussion 1573-4. 2008
  8. ncbi request reprint Prenatal diagnosis of diastematomyelia
    Pascale Sonigo-Cohen
    Pediatric Radiology Department, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Childs Nerv Syst 19:555-60. 2003
  9. ncbi request reprint Congenital disorders of glycosylation type I: a rare but new cause of hyperechoic kidneys in infants and children due to early microcystic changes
    Lucie Hertz-Pannier
    Department of Paediatric Radiology, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Pediatr Radiol 36:108-14. 2006
  10. doi request reprint Safety and accuracy of 64-slice computed tomography coronary angiography in children after the arterial switch operation for transposition of the great arteries
    Phalla Ou
    University Rene Descartes Paris V, UFR Necker Enfants Malades, Department of Pediatric Radiology, 149 rue de Sevres, Paris Cedex 15, France
    JACC Cardiovasc Imaging 1:331-9. 2008

Detail Information

Publications77

  1. ncbi request reprint 1H MRS spectroscopy evidence of cerebellar high lactate in mitochondrial respiratory chain deficiency
    N Boddaert
    Service de Radiologie Pediatrique, U797, Hopital Necker Enfants Malades, 149 rue de Sevres, Paris, France
    Mol Genet Metab 93:85-8. 2008
    ..1H MRS spectroscopy evidence of lactate peak was found in the cerebellum of 9/11 cases, while no lactate was detected in the putamen in 8/11. We suggest using 1H MRS in cerebellar atrophy in the diagnosis of mitochondrial RCD...
  2. ncbi request reprint Brain vascular malformations in the fetus: diagnosis and prognosis
    Francis Brunelle
    Pediatric Radiology, Groupe Hospitalier Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Childs Nerv Syst 19:524-8. 2003
    ..Other malformations are not seen. Ultrasound makes the diagnosis by showing a "cystic" structure in the posterior fossa. Colour Doppler shows the high flow...
  3. ncbi request reprint Fetal CT
    Francis Brunelle
    Service de Radiologie Pediatrique, Groupe Hospitalier Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Childs Nerv Syst 19:415-7. 2003
    ..Fetal CT is helpful in the diagnosis of bony anomalies, particularly with 3D reconstructions...
  4. ncbi request reprint Noninvasive diagnosis of brain tumours in children
    F Brunelle
    Hopital des Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    Childs Nerv Syst 16:731-4. 2000
    ..New techniques, such as spectroscopy and diffusion, may help to characterise further brain tumours in children preoperatively...
  5. ncbi request reprint Congenital hyperinsulinism: pancreatic [18F]fluoro-L-dihydroxyphenylalanine (DOPA) positron emission tomography and immunohistochemistry study of DOPA decarboxylase and insulin secretion
    Pascale de Lonlay
    Departement de Pediatrie, Hopital Necker Enfants Malades, Universite Paris Descartes, Faculte de Medecine, 149 rue de Sevres, 75743 Paris Cedex 15, France
    J Clin Endocrinol Metab 91:933-40. 2006
    ..Preoperative differential diagnosis was based on pancreatic venous sampling, a technically demanding technique...
  6. doi request reprint Value of 18F-fluoro-L-dopa PET in the preoperative localization of focal lesions in congenital hyperinsulinism
    Carmen Capito
    Departments of Pediatric Surgery, Radiology, Pathology, and Pediatrics, Necker Enfants Malades Hospital, AP HP, 75015 Paris, France
    Radiology 253:216-22. 2009
    ....
  7. ncbi request reprint [MRI and fetal multidetector CT in the diagnosis of fetal malformations]
    Francis Brunelle
    Radiologie Pédiatrique, Hopital des Enfants Malades, 147, rue de Sevres, 75743 Paris Cedex 15
    Bull Acad Natl Med 192:1559-73; discussion 1573-4. 2008
    ..We reviewed 2885 fetal MRI examinations. Fetal computed tomography is gradually replacing plain maternal abdominal radiography. We examined 90 CT films for fetal bone malformations...
  8. ncbi request reprint Prenatal diagnosis of diastematomyelia
    Pascale Sonigo-Cohen
    Pediatric Radiology Department, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Childs Nerv Syst 19:555-60. 2003
    ..We present three cases of fetal diastematomyelia investigated using a multimodal prenatal work-up (US, MRI, 3D-CT)...
  9. ncbi request reprint Congenital disorders of glycosylation type I: a rare but new cause of hyperechoic kidneys in infants and children due to early microcystic changes
    Lucie Hertz-Pannier
    Department of Paediatric Radiology, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Pediatr Radiol 36:108-14. 2006
    ..Congenital disorders of glycosylation (CDGs) are a rapidly growing family of inherited disorders due to defects in the synthesis of the glycans of glycoproteins or other glycoconjugates...
  10. doi request reprint Safety and accuracy of 64-slice computed tomography coronary angiography in children after the arterial switch operation for transposition of the great arteries
    Phalla Ou
    University Rene Descartes Paris V, UFR Necker Enfants Malades, Department of Pediatric Radiology, 149 rue de Sevres, Paris Cedex 15, France
    JACC Cardiovasc Imaging 1:331-9. 2008
    ....
  11. ncbi request reprint Neocortical neuronal arrangement in LIS1 and DCX lissencephaly may be different
    Geraldine Viot
    Département de génétique, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    Am J Med Genet A 126:123-8. 2004
    ....
  12. doi request reprint Comparison between ultrasound and magnetic resonance imaging in assessment of fetal cytomegalovirus infection
    Olivier Picone
    Maternité, Hopital Necker Enfants Malades, AP HP, Université René Descartes 149 rue de Sèvres, 75015 Paris, France
    Prenat Diagn 28:753-8. 2008
    ..To evaluate whether fetal brain magnetic resonance imaging (MRI) adds useful information to the one obtained by ultrasound in fetuses with cytomegalovirus (CMV) infection...
  13. ncbi request reprint Angiocentric neuroepithelial tumor (ANET): a new epilepsy-related clinicopathological entity with distinctive MRI
    Arielle Lellouch-Tubiana
    Department of Neuropathology, Universite Paris Descartes, Faculte de Medecine, Paris, France
    Brain Pathol 15:281-6. 2005
    ..Immunohistochemical neuronal markers (neurofilament protein, synaptophysin and chromogranin) confirm the presence of a neuronal cell component. Therefore, the term angiocentric neuroepithelial tumor (ANET) is proposed...
  14. ncbi request reprint Hyperinsulinemic hypoglycemia in children
    P de Lonlay
    Necker Hospital, Paris, France
    Ann Endocrinol (Paris) 65:96-8. 2004
  15. ncbi request reprint Images in cardiovascular medicine. Definitive diagnosis of obstructed total anomalous pulmonary venous drainage in a critically ill newborn with high-resolution computed tomography
    Phalla Ou
    Department of Pediatric Radiology, University Rene Descartes Paris V, Hopital Necker Enfants Malades, 149, rue de Sèvres 75743 PARIS cedex 15, France
    Circulation 114:e646-7. 2006
  16. ncbi request reprint Definitive diagnosis and surgical planning of H-type tracheoesophageal fistula in a critically ill neonate: first experience using air distension of the esophagus during high-resolution computed tomography acquisition
    Phalla Ou
    Department of Pediatric Radiology, University Rene Descartes Paris V, Hopital Necker Enfants Malades, AP HP, Paris, France
    J Thorac Cardiovasc Surg 133:1116-7. 2007
  17. ncbi request reprint Images in cardiovascular medicine. Definitive diagnosis of pulmonary artery sling in a critically ill infant with high-resolution computed tomography
    Phalla Ou
    Department of Pediatric Radiology, University Rene Descartes Paris V, Hopital Necker Enfants Malades, 149, rue de Sèvres 75743 PARIS cedex 15, France
    Circulation 115:e398-9. 2007
  18. pmc Three-dimensional CT scanning: a new diagnostic modality in congenital heart disease
    Phalla Ou
    University Rene Descartes Paris 5, Department of Paediatric Radiology, Hôpital Necker Enfants Malades AP HP, Paris, France
    Heart 93:908-13. 2007
    ....
  19. ncbi request reprint Unusual systemic venous return with absence of superior caval veins
    Phalla Ou
    Department of Pediatric Radiology, University Rene Descartes Paris V, Hopital Necker Enfants Malades, Paris, France
    J Thorac Cardiovasc Surg 133:1368-9. 2007
  20. ncbi request reprint Late plasticity for language in a child's non-dominant hemisphere: a pre- and post-surgery fMRI study
    Lucie Hertz-Pannier
    Department of Medical Research, Service Hospitalier Frederic Joliot, CEA and Institut Federatif de Recherche 49, France
    Brain 125:361-72. 2002
    ..It also suggests a limit for removal of the dominant hemisphere beyond the age of 6 years, a classical limit for the critical period of language acquisition...
  21. ncbi request reprint [Multislice CT scan in congenital heart disease]
    P Ou
    Radiologie Pédiatrique, Hopital Necker Enfants Malades, Paris
    Arch Mal Coeur Vaiss 99:497-502. 2006
    ..This report describes the different acquisition protocols adapted for children and illustrates the present role of volumic CT scanner in congenital heart disease by clinical examples of everyday clinical practice...
  22. ncbi request reprint Superior temporal sulcus anatomical abnormalities in childhood autism: a voxel-based morphometry MRI study
    N Boddaert
    ERM 0205 INSERM CEA, Service Hospitalier Frederic Joliot, CEA, 91406, Orsay, France
    Neuroimage 23:364-9. 2004
    ..Therefore, the convergent anatomical and functional temporal abnormalities observed in autism may be important in the understanding of brain behavior relationships in this severe developmental disorder...
  23. ncbi request reprint [Brain functional MRI: physiological, technical, and methodological bases, and clinical applications]
    L Hertz-Pannier
    Radiologie Pédiatrique, Hopital Necker Enfants Malades, Paris
    J Radiol 81:717-30. 2000
    ..Functional MRI is now becoming an essential tool in the neurofunctional work-up of many neurosurgery patients, as well as the reference method to image normal or pathologic functional brain organization in adults and children...
  24. ncbi request reprint Determination of the anatomical location of an antenatal intestinal occlusion by magnetic resonance imaging
    A Benachi
    Maternité, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Ultrasound Obstet Gynecol 18:163-5. 2001
    ..We report herein the feasibility of diagnosing and locating a fetal small-intestine occlusion with the use of magnetic resonance imaging...
  25. ncbi request reprint [Anomalous left main coronary artery with an inter-aorto-pulmonary trajectory: diagnostic value of 64-slice CT scan with cardiac synchronisation]
    P Ou
    Radiologie Pédiatrique, Universite Rene Descartes, Paris 5, Hopital Necker Enfants Malades, Paris
    Arch Mal Coeur Vaiss 100:454-7. 2007
    ..In the authors' experience, the investigation is performed systematically when an anomalous coronary artery is suspected, in addition to echocardiography and instead of conventional coronary angiography...
  26. ncbi request reprint Dominantly inherited hyperinsulinaemic hypoglycaemia
    P de Lonlay
    INSERM U393 and Department of Pediatrics, Hopital Necker Enfants Malades, Paris, France
    J Inherit Metab Dis 28:267-76. 2005
    ..HI is a heterogeneous disease associated with several genes, various mechanisms of pathogenic mutations and different transmissions (Dunne et al 2004)...
  27. ncbi request reprint Anatomical and functional brain imaging evidence of lenticulo-insular anomalies in Smith Magenis syndrome
    N Boddaert
    Service de Genetique, Necker Enfants Malades, 75015 Paris, France
    Neuroimage 21:1021-5. 2004
    ..The identification of localized brain anomalies in SMS may help in understanding how this well-defined genetic entity can lead to a relatively specific severe neurobehavioral syndrome...
  28. ncbi request reprint CT angiography of the artery of Adamkiewicz with 64-section technology: first experience in children
    P Ou
    Department of Pediatric Radiology, Hopital Necker Enfants Malades, AP HP, Paris, France
    AJNR Am J Neuroradiol 28:216-9. 2007
    ..The aim of our study was to investigate the ability of 64-section CT for assessing the AKA in children...
  29. ncbi request reprint Parieto-occipital grey matter abnormalities in children with Williams syndrome
    N Boddaert
    ERM 0205 INSERM CEA, Service Hospitalier Frederic Joliot, 4, place du General Leclerc, 91406 Orsay, France
    Neuroimage 30:721-5. 2006
    ..Additionally, our study provides support for the use of advanced structural imaging techniques in children, in order to improve our understanding of neurobehavioral phenotypes associated with well-defined genetic disorders...
  30. ncbi request reprint Intellectual prognosis of the Dandy-Walker malformation in children: the importance of vermian lobulation
    N Boddaert
    Paediatric Radiology Department, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    Neuroradiology 45:320-4. 2003
    ..Preservation of cerebrocerebellar pathways and neonatal plasticity could explain the normal intellectual development. These findings might be useful in prenatal diagnosis...
  31. ncbi request reprint Emergency management of deeply comatose children with acute rupture of cerebral arteriovenous malformations
    P G Meyer
    Department of Paediatric Anaesthesia, Assistance Publique Hopitaux de Paris Université Paris V, Centre Hospitalier Universitaire Necker Enfants Malades, France
    Can J Anaesth 47:758-66. 2000
    ..To assess the impact of emergency management on mortality and morbidity of acute rupture of cerebral arteriovenous malformations resulting in deep coma in children, and the factors predicting outcome...
  32. ncbi request reprint Skin markers of occult spinal dysraphism in children: a review of 54 cases
    David Guggisberg
    Department of Dermatology, Groupe Hospitalier Necker Enfants Malades, Paris, France
    Arch Dermatol 140:1109-15. 2004
    ....
  33. doi request reprint Changes in intracranial CSF distribution after ETV
    Federico Di Rocco
    Department of Paediatric Neurosurgery, Necker Enfants Malades Hospital, 156 rue de Vaugirard, 75015 Paris, France
    Childs Nerv Syst 28:997-1002. 2012
    ..The aim of this prospective study was to analyze the changes in cerebrospinal fluid (CSF) distribution after endoscopic third ventriculocisternostomy (ETV)...
  34. ncbi request reprint [Radiological innovations in the screening and diagnosis of the inborn errors of metabolism]
    Nathalie Boddaert
    Service de Radiologie Pediatrique, ERM 0205, Hopital Necker Enfants Malades, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Med Sci (Paris) 21:981-6. 2005
    ..PET with [18F]Fluoro-L-DOPA has been validated as a reliable test to differentiate diffuse and focal HI and is now a major differential diagnosis tool in infantile hyperinsulinemic hypoglycaemia...
  35. ncbi request reprint Primary pulmonary alveolar proteinosis: computed tomography features at diagnosis
    Laureline Berteloot
    Department of Pediatric Radiology, Hopital Necker Enfants Malades, Assistance Publique des Hopitaux de Paris, 149 rue de Sevres, 75743, Paris Cedex 15, France
    Pediatr Radiol 44:795-802. 2014
    ..Early diagnosis allows setting up of therapeutic lung lavages, which reduces the need for oxygen supplementation and weight gain...
  36. ncbi request reprint [Brain imaging in seizures]
    David Grevent
    Universite Paris Descartes, AP HP, Hopital Necker Enfants Malades, Inserm U1000, Service de Radiologie Pediatrique, 75015 Paris, France
    Rev Prat 62:1391-4. 2012
    ..Contrast injection is mandatory especially when abnormal findings are seen on the MRI precontrast images...
  37. ncbi request reprint An unusual case of left aberrant innominate artery with right aortic arch: evaluation with high-resolution CT
    Giulio Calcagni
    Department of Pediatric Cardiology, Hopital Necker Enfants Malades, University Rene Descartes Paris 5, 149 rue de Sevres, Paris Cedex 15, France
    Pediatr Radiol 38:115-7. 2008
    ..High-resolution CT was used to completely assess the abnormal anatomy and the relationship with the airway, as well as to guide the surgical approach for its correction...
  38. ncbi request reprint Infected pulmonary artery aneurysms: CT imaging findings
    Phalla Ou
    Department of Pediatric Radiology, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Eur J Cardiothorac Surg 29:248. 2006
  39. ncbi request reprint Diagnostic value of high-resolution CT in the evaluation of chronic infiltrative lung disease in children
    Stephanie Vrielynck
    Service de pneumologie et allergologie pédiatriques, Hopital Necker Enfants Malades, Assistance Publique des Hopitaux de Paris, 149 rue de Sevres, 75015 Paris, France
    AJR Am J Roentgenol 191:914-20. 2008
    ..The purpose of this study was to evaluate the accuracy of CT in the diagnosis of chronic infiltrative lung disease in children...
  40. ncbi request reprint Dandy-Walker malformation: prenatal diagnosis and prognosis
    O Klein
    Service de neurochirurgie pédiatrique, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Childs Nerv Syst 19:484-9. 2003
    ..If any one of the previous criteria were not met, the malformation was considered distinct from DWM...
  41. ncbi request reprint Clinical features of 52 neonates with hyperinsulinism
    P de Lonlay-Debeney
    Department of Pediatrics, Hopital des Enfants Malades, Paris, France
    N Engl J Med 340:1169-75. 1999
    ..Neonatal hyperinsulinemic hypoglycemia is often resistant to medical therapy and is often treated with near-total pancreatectomy. However, the pancreatic lesions may be focal and treatable by partial pancreatic resection...
  42. ncbi request reprint [Prenatal semiology of diastematomyelia]
    L Chat
    , , , 75743 Paris Cedex 15
    J Radiol 82:661-3. 2001
    ..In addition to providing diagnosis, prenatal evaluation helps differentiate between diastematomyelia with good or bad prognosis...
  43. ncbi request reprint Factitious hyperinsulinism leading to pancreatectomy: severe forms of Munchausen syndrome by proxy
    Irina Giurgea
    Department of Metabolic Disorders, Hopital Necker Enfants Malades, 75015 Paris, France
    Pediatrics 116:e145-8. 2005
    ..One percent (2 of 250) of all cases of hyperinsulinemic hypoglycemia in our unit have been identified as Munchausen syndrome by proxy. Atypical disease history should raise the question of factitious hypoglycemia...
  44. ncbi request reprint Antenatal manifestations of mitochondrial respiratory chain deficiency
    Jürgen Christoph von Kleist-Retzow
    Unite de Recherches sur les Handicaps Genetiques de l Enfant, INSERM U 393, Hopital des Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    J Pediatr 143:208-12. 2003
    ..To review the antenatal manifestations of disorders of oxidative phosphorylation...
  45. ncbi request reprint Removal of a chopstick out of the cavernous sinus, pons, and cerebellar vermis through the superior orbital fissure
    Delphine Mitilian
    Department of Paediatric Neurosurgery, Necker Enfants Malades Hospital, 156 rue de Vaugirard, 75015 Paris, France
    Acta Neurochir (Wien) 151:1295-7. 2009
    ..The foreign body was successfully pulled out in one piece surgically...
  46. ncbi request reprint Surgical treatment of an unusual case of pelvic extramedullary hematopoiesis
    Naziha Khen-Dunlop
    Department of Pediatric Surgery, Necker Enfants Malades Hospital, 75015 Paris, France
    J Pediatr Surg 41:e13-5. 2006
    ..Whereas surgery is limited to spinal cord compression in paraspinal extramedullary hematopoiesis, this observation argues for surgical treatment in symptomatic intraabdominal extramedullary hematopoiesis when medical treatment fails...
  47. doi request reprint A cognitive and affective pattern in posterior fossa strokes in children: a case series
    Manoelle Kossorotoff
    Paediatric Neurology Department, Hopital Necker Enfants Malades, APHP, 149 rue de Sevres, Paris, France
    Dev Med Child Neurol 52:626-31. 2010
    ..Although motor and dysautonomic symptoms are common, to our knowledge cognitive and affective deficits have not been described in the paediatric literature. Our aim, therefore, was to describe these symptoms and deficits...
  48. ncbi request reprint Thoracic CT in pediatric patients with difficult-to-treat asthma
    Valentine Marchac
    Service de Pneumologie et d Allergologie Pediatriques, Hopital Necker Enfants Malades, 149 rue de Sevres, 75015 Paris, France
    AJR Am J Roentgenol 179:1245-52. 2002
    ..The aim of this study was to establish objective, simple criteria for bronchial wall thickening in children with difficult-to-treat asthma...
  49. ncbi request reprint Pancreatic arterial calcium stimulation in the diagnosis and localisation of persistent hyperinsulinemic hypoglycaemia of infancy
    V Chigot
    Department of Radiology, Hopital des Enfants Malades, 149 rue de Sevres, 75 015 Paris, France
    Pediatr Radiol 31:650-5. 2001
    ..However, hypoglycaemia is necessary to analyse the results and PVS is technically challenging. Pancreatic arterial calcium stimulation (PACS) is technically easier and does not require hypoglycaemia...
  50. ncbi request reprint Contribution of fetal MR imaging in the prenatal diagnosis of Zellweger syndrome
    F Mochel
    Service de Radiologie Pediatrique, Hopital Necker Enfants Malades, Paris, France
    AJNR Am J Neuroradiol 27:333-6. 2006
    ..The high level of resolution of MR imaging, which allows analysis of cerebral gyration and myelination, facilitates the prenatal diagnosis of complex polymalformative syndromes such as ZS...
  51. ncbi request reprint [Congenital hyperinsulinism of infancy: surgical treatment in 60 cases of focal form]
    C Cretolle
    Service de Chirurgie Pediatrique, Hopital Necker Enfants Malades, Assistance Publique Hopitaux de Paris, 149, rue de Sevres, 75743 Paris Cedex 15, France
    Arch Pediatr 12:258-63. 2005
    ..One patient is still in hypoglycaemia from unrecognized lesion; insulin-dependent diabetes mellitus occurred in one case nine years after surgery (a near-total pancreatectomy has been performed because of unknown focal form, in 1985)...
  52. ncbi request reprint Neonatal ruptured intracranial aneurysms: case report and literature review
    Y van Raay
    Department of Paediatric Neurosurgery, Hopital Necker Enfants Malades, 149 rue de Sevres, Paris 75015, France
    Childs Nerv Syst 25:1025-33. 2009
    ..Intracranial aneurysms are exceptional in neonatal patients: There are only 16 cases previously reported. We describe the first case of neonatal posterior inferior cerebellar artery (PICA) aneurysm and review the literature...
  53. pmc Paternal mutation of the sulfonylurea receptor (SUR1) gene and maternal loss of 11p15 imprinted genes lead to persistent hyperinsulinism in focal adenomatous hyperplasia
    V Verkarre
    INSERM UR 383, Hopital Necker Enfants Malades, University Paris V, 75743 Paris Cedex 15, France
    J Clin Invest 102:1286-91. 1998
    ....
  54. ncbi request reprint [Imaging of pediatric head injury]
    F Brunelle
    Service de Radiologie Pediatrique, Hopital des Enfants Malades, 149, rue de Sevres, 75743 Paris Cedex 15
    J Radiol 86:253-62. 2005
    ..The main types of injuries and their appearances at different imaging modalities will be reviewed. CT remains a valuable tool but MRI also is helpful at the time of initial evaluation as well as for prognostic evaluation...
  55. ncbi request reprint [Hyperinsulinism in children: new concepts - the role of imaging]
    Francis Brunelle
    Radiologie Pédiatrique, Hopital Necker Enfants Malades, Paris
    Bull Acad Natl Med 192:59-70; discussion 71-2. 2008
    ..Biochemical and genetic studies show that focal and diffuse forms are due to various mutations of chromosome 11...
  56. ncbi request reprint The Knudson's two-hit model and timing of somatic mutation may account for the phenotypic diversity of focal congenital hyperinsulinism
    Irina Giurgea
    INSERM U654, and Department of Genetics, Hopital Henri Mondor, 51 Avenue du Marechal de Lattre de Tassigny, 94010 Creteil Cedex, France
    J Clin Endocrinol Metab 91:4118-23. 2006
    ..5. Plurifocal or large forms of focal CHI are a cause of apparent failure of surgery, and their underlying mechanism has not been thoroughly investigated...
  57. ncbi request reprint Facial appearance in persistent hyperinsulinemic hypoglycemia
    Pascale de Lonlay
    Departement de Pediatrie, INSERM U383, Hopital Necker Enfants Malades, Paris, France
    Am J Med Genet 111:130-3. 2002
    ..However, to date, facial anomalies have not been noted in infants of diabetic mothers and inversely, malformations that are commonly reported in infants of diabetic mothers were not present in our hyperinsulinemic patients...
  58. ncbi request reprint Functional imaging of the pancreas: the role of [18F]fluoro-L-DOPA PET in the diagnosis of hyperinsulinism of infancy
    Maria Joao Ribeiro
    Life Sciences Division, Biomedical Imaging Institute, Frédéric Joliot Hospital, CEA, Orsay, France
    Endocr Dev 12:55-66. 2007
    ..Therefore, we have evaluated the use of PET with [18F]fluoro-L-DOPA, a precursor of catecholamines, to image the pancreas and distinguish focal from diffuse HI...
  59. ncbi request reprint Acute insulin responses to calcium and tolbutamide do not differentiate focal from diffuse congenital hyperinsulinism
    Irina Giurgea
    Department of Pediatrics, Hopital Necker Enfants Malades, 75743 Paris, France
    J Clin Endocrinol Metab 89:925-9. 2004
    ..We conclude that AIRs to calcium and tolbutamide stimulation tests are not sufficient to differentiate the focal from the diffuse CHI patients...
  60. ncbi request reprint Fetal lung volume estimated by 3-dimensional ultrasonography and magnetic resonance imaging in cases with isolated congenital diaphragmatic hernia
    Rodrigo Ruano
    Maternité, Hopital Necker Enfants Malades, Paris, France
    J Ultrasound Med 23:353-8. 2004
    ..To assess the agreement of 3-dimensional ultrasonography and magnetic resonance imaging in estimating fetal lung volume in cases with isolated congenital diaphragmatic hernia...
  61. ncbi request reprint The added value of [18F]fluoro-L-DOPA PET in the diagnosis of hyperinsulinism of infancy: a retrospective study involving 49 children
    Maria Joao Ribeiro
    Biomedical Imaging Institute, Life Sciences Division, Commissariat a l Energie Atomique, Frédéric Joliot Hospital, 4 Place du General Leclerc, Orsay, France
    Eur J Nucl Med Mol Imaging 34:2120-8. 2007
    ..Here, we report the diagnostic value of PET with [(18)F]fluoro-L-DOPA in distinguishing focal from diffuse HI...
  62. ncbi request reprint Characterization of hyperinsulinism in infancy assessed with PET and 18F-fluoro-L-DOPA
    Maria Joao Ribeiro
    Service Hospitalier Frederic Joliot, Departement de Recherche Medicale, Direction des Sciences du Vivant, Commissariat a l Energie Atomique, Orsay, France
    J Nucl Med 46:560-6. 2005
    ..Therefore, the aim of this study was (a) to evaluate the use of PET with 18F-fluoro-L-dihydroxyphenylalanine (18F-fluoro-L-DOPA) and (b) to distinguish between focal and diffuse HI...
  63. ncbi request reprint Autism: functional brain mapping of exceptional calendar capacity
    Nathalie Boddaert
    Service Hospitalier Frederic Joliot, DRM, DSV, CEA, 4 Place du General Leclerc 91406, Orsay, France
    Br J Psychiatry 187:83-6. 2005
    ..Autistic savants' are individuals with autism who have extraordinary skills. Brain mechanisms underlying such capacities are still unknown...
  64. ncbi request reprint Autism, the superior temporal sulcus and social perception
    Monica Zilbovicius
    URM 0205 Brain Imaging in Psychiatry, INSERM CEA, Service Hospitalier Frederic Joliot, CEA, 4 Place du General Leclerc, Orsay 91406, France
    Trends Neurosci 29:359-66. 2006
    ..This review is part of the INMED/TINS special issue "Nature and nurture in brain development and neurological disorders", based on presentations at the annual INMED/TINS symposium (http://inmednet.com/)...
  65. ncbi request reprint Abnormal cortical voice processing in autism
    Hélène Gervais
    ERM 0205, INSERM CEA, DRM, DSV, Service Hospitalier Frederic Joliot, 4, place du General Leclerc, 91406, Orsay, France
    Nat Neurosci 7:801-2. 2004
    ..These findings suggest abnormal cortical processing of socially relevant auditory information in autism...
  66. ncbi request reprint Heterogeneity of persistent hyperinsulinaemic hypoglycaemia. A series of 175 cases
    Pascale de Lonlay
    fédération de pédiatrie, Hopital Necker Enfants Malades, Paris, France
    Eur J Pediatr 161:37-48. 2002
    ..Conclusion: the clinical severity of hyperinsulinism varies mainly with age at onset of hypoglycaemia. The heterogeneity of hyperinsulinism has major consequences in terms of therapeutic outcome and genetic counselling...
  67. ncbi request reprint Molecular mechanisms of neonatal hyperinsulinism
    Irina Giurgea
    INSERM U654 and Department of Genetics, Hopital Henri Mondor, Creteil, France
    Horm Res 66:289-96. 2006
    ..However, secondary causes of hyperinsulinism have to be considered such as fatty acid oxidation deficiency, congenital disorders of glycosylation and factitious hypoglycaemia secondary to Munchausen by proxy syndrome...
  68. ncbi request reprint Perception of complex sounds in autism: abnormal auditory cortical processing in children
    Nathalie Boddaert
    Commissariat a l Energie Atomique, Service Hospitalier Frederic Joliot, 4 Place du General Leclerc, 91406 Orsay, France
    Am J Psychiatry 161:2117-20. 2004
    ..Here, they investigated whether this abnormal cortical processing was also present in children with primary autism...
  69. ncbi request reprint Classification of venous malformations in children and implications for sclerotherapy
    Stefan Puig
    Department of Radiology, University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Pediatr Radiol 33:99-103. 2003
    ....
  70. ncbi request reprint Selective iron chelation in Friedreich ataxia: biologic and clinical implications
    Nathalie Boddaert
    Pediatric Radiology Unit, Institut National de la Sante et de la Recherche Medicale, Hopital Necker Enfants Malades, université Paris V René Descartes, Paris, France
    Blood 110:401-8. 2007
    ..The use of moderate chelation for relocating iron from areas of deposition to areas of deprivation has clinical implications for various neurodegenerative and hematologic disorders...
  71. ncbi request reprint Perinatal three-dimensional color power Doppler ultrasonography of vein of Galen aneurysms
    Rodrigo Ruano
    Maternité, Hopital Necker Enfants Malades, 149 rue de Sèvres 75743 Paris 15, France
    J Ultrasound Med 22:1357-62. 2003
    ..To present the prenatal and postnatal three-dimensional color power Doppler ultrasonographic features in cases of vein of Galen aneurysmal malformation...
  72. ncbi request reprint Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome
    Guntram Borck
    INSERM U781 and Department of Medical Genetics, Hopital Necker Enfants Malades, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Paris, France
    Hum Mutat 29:966-74. 2008
    ....
  73. ncbi request reprint Left coronary to right ventricle fistula in a child: management strategy based on cardiac-gated 64-slice CT
    Davide Marini
    Department of Paediatric Cardiology, Hopital Necker Enfants Malades, AP HP, University Rene Descartes Paris V, Paris, France
    Pediatr Radiol 38:325-7. 2008
    ..Multiplanar and 3-D reconstruction offer invaluable information to plan the best therapeutic strategy in this setting. We provide evidence for the expanding clinical role of MSCT for coronary artery imaging in children...
  74. ncbi request reprint Coexistence in the same family of both focal and diffuse forms of hyperinsulinism
    Vassili Valayannopoulos
    Department of Metabolic Disorders, Hopital Necker Enfants Malades, Paris, France
    Diabetes Care 30:1590-2. 2007
  75. ncbi request reprint Massive subdural haematomas in Menkes disease mimicking shaken baby syndrome
    Marie Cecile Nassogne
    Service de Neurologie Pediatrique, Cliniques Universitaires Saint Luc, Avenue Hippocrate 10 1062, 1200 Brussels, Belgium
    Childs Nerv Syst 18:729-31. 2002
    ..Cardinal features include hair abnormalities, facial dysmorphism, severe neurological impairment, hypothermia, arterial anomalies, bone abnormalities and a fatal outcome...
  76. ncbi request reprint Pediatric coronary artery bypass after arterial switch operation: noninvasive evaluation with ECG-gated 64-slice CT in routine practice
    Monia Jemmali
    University Rene Descarte Paris 5, Hopital Necker Enfants Malades, Department of Pediatric Cardiology, Paris, France
    Ann Thorac Surg 84:1398-9. 2007
    ....
  77. ncbi request reprint Autism severity and temporal lobe functional abnormalities
    Isabelle Gendry Meresse
    ERM 0205 Institut National de la Sante et de la Recherche Médicale CEA, Service Hospitalier F Joliot, DSV, DRM, CEA, Orsay, France
    Ann Neurol 58:466-9. 2005
    ..The more severe the autistic syndrome, the more rCBF is low in this region, suggesting that left superior temporal hypoperfusion is related to autistic behavior severity...