Jean Luc Brun
Brun J, Rouzier R, Uzan S, Darai E. External validation of a laparoscopic-based score to evaluate resectability of advanced ovarian cancers: clues for a simplified score. Gynecol Oncol. 2008;110:354-9 pubmed publisher
..ROC curve analysis gave an AUC of 0.68. This simplified laparoscopy-based score was at least as accurate as the Fagotti score to predict resectability. ..
Brun J, Rouzier R, Selle F, Houry S, Uzan S, Darai E. Neoadjuvant chemotherapy or primary surgery for stage III/IV ovarian cancer: contribution of diagnostic laparoscopy. BMC Cancer. 2009;9:171 pubmed publisher
..Diagnostic laparoscopy is useful for identifying patients with stage III/IV ovarian cancer who qualify for primary cytoreduction. Surgeon experience was a determining factor for the success of complete cytoreduction. ..
Brun J, Cortez A, Commo F, Uzan S, Rouzier R, Darai E. Serous and mucinous ovarian tumors express different profiles of MMP-2, -7, -9, MT1-MMP, and TIMP-1 and -2. Int J Oncol. 2008;33:1239-46 pubmed
..In conclusion, our results support the differential expression in MMPs and TIMPs of ovarian tumors according to serous or mucinous histology. ..