Research Topics
Genomes and GenesSpecies | Peter BrodersenSummaryCountry: France Publications
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Detail Information
Publications
Revisiting the principles of microRNA target recognition and mode of actionPeter Brodersen
Institut de Biologie Moleculaire des Plantes, Centre National de la Recherche Scientifique, 12 rue du Général Zimmer, 67084 Strasbourg Cedex, France
Nat Rev Mol Cell Biol 10:141-8. 2009..Generally thought to be merely a degradation mechanism, we propose that this might also be a biogenesis mechanism for biologically functional, non-coding RNA fragments...
Isoprenoid biosynthesis is required for miRNA function and affects membrane association of ARGONAUTE 1 in ArabidopsisPeter Brodersen
Institut de Biologie Moléculaire des Plantes du Centre National de la Recherche Scientifique, Unité Propre de Recherche 2357, 67084 Strasbourg Cedex, France
Proc Natl Acad Sci U S A 109:1778-83. 2012..These results suggest a possible basis for the requirement of isoprenoid biosynthesis for the activity of plant miRNAs, and unravel mechanistic features shared with their metazoan counterparts...
Widespread translational inhibition by plant miRNAs and siRNAsPeter Brodersen
Institut de Biologie Moleculaire des Plantes du CNRS, Unité Propre de Recherche 2357, 12 rue du Général Zimmer, 67084 Strasbourg Cedex, France
Science 320:1185-90. 2008..Also as in animals, the decapping component VARICOSE (VCS)/Ge-1 is required for translational repression by miRNAs, which suggests that the underlying mechanisms in the two kingdoms are related...
The diversity of RNA silencing pathways in plantsPeter Brodersen
, 12, , 67084 Strasbourg Cedex, France
Trends Genet 22:268-80. 2006..Here, we review recent developments in the plant RNA silencing field that have identified components of specific silencing pathways and have shed light on the mechanisms and biological roles of RNA silencing in plants...
