Jean Breton

Summary

Country: France

Publications

  1. ncbi request reprint Simultaneous use of DGGE and DHPLC to screen TP53 mutations in cancers of the esophagus and cardia from a European high incidence area (Lower Normandy, France)
    Jean Breton
    Groupe Régional d Etudes sur le Cancer, Universite de Caen Basse Normandie, Laboratoire de Cancerologie Experimentale, Centre Françiois Baclesse, Route de Lion Mer, 14 076 Caen cedex 05, France
    Mutagenesis 18:299-306. 2003
  2. ncbi request reprint Measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine in peripheral blood mononuclear cells: optimisation and application to samples from a case-control study on cancers of the oesophagus and cardia
    Jean Breton
    University of Leeds, Faculty of Medicine and Health, Leeds Institute for Health and Therapeutics, Molecular Epidemiology Unit, Leeds LS2 9JT, UK
    Free Radic Res 39:21-30. 2005
  3. ncbi request reprint Specificity of TP53 mutation screening methods in cancerous tissues
    Jean Breton
    Int J Cancer 118:254-5; author reply 256. 2006
  4. doi request reprint Proteomic screening of a cell line model of esophageal carcinogenesis identifies cathepsin D and aldo-keto reductase 1C2 and 1B10 dysregulation in Barrett's esophagus and esophageal adenocarcinoma
    Jean Breton
    Molecular Epidemiology Unit, Centre for Epidemiology and Biostatistics, Leeds Institute of Genetics, Health and Therapeutics, Clarendon Way, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Proteome Res 7:1953-62. 2008

Detail Information

Publications4

  1. ncbi request reprint Simultaneous use of DGGE and DHPLC to screen TP53 mutations in cancers of the esophagus and cardia from a European high incidence area (Lower Normandy, France)
    Jean Breton
    Groupe Régional d Etudes sur le Cancer, Universite de Caen Basse Normandie, Laboratoire de Cancerologie Experimentale, Centre Françiois Baclesse, Route de Lion Mer, 14 076 Caen cedex 05, France
    Mutagenesis 18:299-306. 2003
    ..This result stresses the limited sensitivity of DHPLC compared with DGGE under the conditions described in this study...
  2. ncbi request reprint Measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine in peripheral blood mononuclear cells: optimisation and application to samples from a case-control study on cancers of the oesophagus and cardia
    Jean Breton
    University of Leeds, Faculty of Medicine and Health, Leeds Institute for Health and Therapeutics, Molecular Epidemiology Unit, Leeds LS2 9JT, UK
    Free Radic Res 39:21-30. 2005
    ..This elevated level of DNA damage in patients can raise interesting issues: is oxidative stress the cause or the result of the pathology? Could this biomarker be used to evaluate chemoprevention trials concerning digestive tract cancers?..
  3. ncbi request reprint Specificity of TP53 mutation screening methods in cancerous tissues
    Jean Breton
    Int J Cancer 118:254-5; author reply 256. 2006
  4. doi request reprint Proteomic screening of a cell line model of esophageal carcinogenesis identifies cathepsin D and aldo-keto reductase 1C2 and 1B10 dysregulation in Barrett's esophagus and esophageal adenocarcinoma
    Jean Breton
    Molecular Epidemiology Unit, Centre for Epidemiology and Biostatistics, Leeds Institute of Genetics, Health and Therapeutics, Clarendon Way, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Proteome Res 7:1953-62. 2008
    ..05) in EA. These proteins may contribute to disease development via effects on apoptosis, transport of bile acids and retinoid metabolism and should be considered as candidates for further mechanistic and clinical investigations...