Francis Couturaud

Summary

Affiliation: Brest University Hospital
Country: France

Publications

  1. ncbi request reprint [Diagnosis of postoperative venous thromboembolism]
    Maria Belen Moscoso
    G E T B O Groupe d Etude de la Thrombose de Bretagne Occidentale, département de médecine interne et pneumologie, Hopital de la Cavale Blanche, 29609 Brest
    Presse Med 32:852-9. 2003
  2. ncbi request reprint Assessment of the risk and prophylactic treatment of venous thromboembolism in the elderly
    F Couturaud
    Groupe d Etude de la Thrombose de Bretagne Occidentale GETBO, Brest, France
    Pathophysiol Haemost Thromb 33:362-5. 2003
  3. ncbi request reprint [The education of asthma patients: proven effectiveness]
    Francis Couturaud
    Departement de medicine interne et pneumologie, CHRU de la Cavele Blanche, 29609 Brest Cedex
    Rev Prat 55:1337-8. 2005
  4. ncbi request reprint High frequency of factor V Leiden in surgical patients with symptomatic venous thromboembolism despite prophylaxis
    Mohamed Baba-Ahmed
    Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France
    Thromb Haemost 97:171-5. 2007
  5. ncbi request reprint Thrombin generation in first-degree relatives of patients with venous thromboembolism who have factor V Leiden. A pilot study
    Francis Couturaud
    G E T B O Groupe d Etude de la Thrombose de Bretagne Occidentale, EA 3878, Department of Internal Medicine and Chest Diseases, University Hospital of Brest, Brest, France
    Thromb Haemost 99:223-8. 2008
  6. ncbi request reprint [Optimum duration of anticoagulant treatment after an episode of venous thromboembolism]
    F Couturaud
    EA 3878 GETBO, département de médecine interne et pneumologie, CHU La Cavale Blanche, 29609 Brest Cedex, France
    Rev Pneumol Clin 64:305-15. 2008
  7. doi request reprint Factors that predict risk of thrombosis in relatives of patients with unprovoked venous thromboembolism
    Francis Couturaud
    Department of Internal Medicine and Chest Diseases, Groupe d Etude de la Thrombose de Bretagne Occidentale, Brest, France
    Chest 136:1537-45. 2009
  8. ncbi request reprint [Prolongation of anti vitamin K treatment for 18 months versus placebo after 6 months treatment of a first episode of ideopathic pulmonary embolism: a mutlicentre, randomised double blind trail. The PADIS-EP Trial]
    F Couturaud
    département de médecine interne et pneumologie, CHU de Brest, France
    Rev Mal Respir 25:885-93. 2008
  9. ncbi request reprint Incidence of venous thromboembolism in first-degree relatives of patients with venous thromboembolism who have factor V Leiden
    Francis Couturaud
    GETBO, EA 3878, Department of Internal Medicine and Chest Diseases, University Hospital Centre La Cavale Blanche, 29609 Brest, Cedex, France
    Thromb Haemost 96:744-9. 2006
  10. ncbi request reprint Predictors of thrombosis in relatives of patients with venous thromboembolism
    Francis Couturaud
    G E T B O Groupe d Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medicine and Chest Diseases, Brest, France
    Curr Opin Pulm Med 16:453-8. 2010

Collaborators

Detail Information

Publications37

  1. ncbi request reprint [Diagnosis of postoperative venous thromboembolism]
    Maria Belen Moscoso
    G E T B O Groupe d Etude de la Thrombose de Bretagne Occidentale, département de médecine interne et pneumologie, Hopital de la Cavale Blanche, 29609 Brest
    Presse Med 32:852-9. 2003
    ..Although many general studies, assessing supplementary examination or diagnostic strategies are available, the proportion of patients concerned by a post-operative context varies...
  2. ncbi request reprint Assessment of the risk and prophylactic treatment of venous thromboembolism in the elderly
    F Couturaud
    Groupe d Etude de la Thrombose de Bretagne Occidentale GETBO, Brest, France
    Pathophysiol Haemost Thromb 33:362-5. 2003
    ..In addition, the development of anticoagulation clinics and new oral anticoagulants should help to reduce anticoagulant related bleeding for an equivalent, or an increased, benefit...
  3. ncbi request reprint [The education of asthma patients: proven effectiveness]
    Francis Couturaud
    Departement de medicine interne et pneumologie, CHRU de la Cavele Blanche, 29609 Brest Cedex
    Rev Prat 55:1337-8. 2005
  4. ncbi request reprint High frequency of factor V Leiden in surgical patients with symptomatic venous thromboembolism despite prophylaxis
    Mohamed Baba-Ahmed
    Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France
    Thromb Haemost 97:171-5. 2007
    ..4; 95% CI, 2.4 to 29). This study shows a close association between the presence of factorV Leiden mutation in symptomatic VTE occurring after surgery despite prophylaxis...
  5. ncbi request reprint Thrombin generation in first-degree relatives of patients with venous thromboembolism who have factor V Leiden. A pilot study
    Francis Couturaud
    G E T B O Groupe d Etude de la Thrombose de Bretagne Occidentale, EA 3878, Department of Internal Medicine and Chest Diseases, University Hospital of Brest, Brest, France
    Thromb Haemost 99:223-8. 2008
    ..3 (95%CI, 2.9-71.2). An abnormal thrombin generation test appears highly predictive for having factor V Leiden and/or other prothrombotic states in first-degree relatives of patients with venous thromboembolism and factor V Leiden...
  6. ncbi request reprint [Optimum duration of anticoagulant treatment after an episode of venous thromboembolism]
    F Couturaud
    EA 3878 GETBO, département de médecine interne et pneumologie, CHU La Cavale Blanche, 29609 Brest Cedex, France
    Rev Pneumol Clin 64:305-15. 2008
    ..However, given the number of unresolved issues, a randomised trial comparing different durations of anticoagulation is needed...
  7. doi request reprint Factors that predict risk of thrombosis in relatives of patients with unprovoked venous thromboembolism
    Francis Couturaud
    Department of Internal Medicine and Chest Diseases, Groupe d Etude de la Thrombose de Bretagne Occidentale, Brest, France
    Chest 136:1537-45. 2009
    ..We aimed to identify risk factors for, and quantify the risk of, venous thromboembolism in first-degree relatives of patients (index case patients) with a first episode of unprovoked venous thromboembolism...
  8. ncbi request reprint [Prolongation of anti vitamin K treatment for 18 months versus placebo after 6 months treatment of a first episode of ideopathic pulmonary embolism: a mutlicentre, randomised double blind trail. The PADIS-EP Trial]
    F Couturaud
    département de médecine interne et pneumologie, CHU de Brest, France
    Rev Mal Respir 25:885-93. 2008
    ....
  9. ncbi request reprint Incidence of venous thromboembolism in first-degree relatives of patients with venous thromboembolism who have factor V Leiden
    Francis Couturaud
    GETBO, EA 3878, Department of Internal Medicine and Chest Diseases, University Hospital Centre La Cavale Blanche, 29609 Brest, Cedex, France
    Thromb Haemost 96:744-9. 2006
    ..FVL is associated with a two- to threefold increase in VTE in first-degree relatives of patients with VTE. No subgroup of relatives was identified who require more than routine prophylaxis because of a particularly high risk of VTE...
  10. ncbi request reprint Predictors of thrombosis in relatives of patients with venous thromboembolism
    Francis Couturaud
    G E T B O Groupe d Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medicine and Chest Diseases, Brest, France
    Curr Opin Pulm Med 16:453-8. 2010
    ..However, if patients do not have a currently recognized thrombophilia it cannot be assumed that their relatives have a normal risk of thrombosis; the patient and their relatives may have a yet to be discovered hereditary abnormality...
  11. doi request reprint [The optimal duration of anticoagulant treatment following pulmonary embolism]
    F Couturaud
    EA 3878 GETBO, IFR 148, CIC INSERM 0502, département de médecine interne et pneumologie, CHU La Cavale Blanche, Brest Cedex, France
    Rev Mal Respir 28:1265-77. 2011
    ..Despite an increasing knowledge of the risk factors for recurrent venous thromboembolism, a number of issues remain unresolved. Randomised trials comparing different durations of anticoagulation are needed...
  12. ncbi request reprint Association of common genetic variations and idiopathic venous thromboembolism. Results from EDITh, a hospital-based case-control study
    Aurelien Delluc
    Université Européeenne de Bretagne, Universite de Brest, Brest, France
    Thromb Haemost 103:1161-9. 2010
    ..In this hospital-based case-control study, two polymorphisms located on the factor XI gene were significantly associated with VTE. Other newly investigated polymorphisms with potentially false negatives may warrant further analyses...
  13. ncbi request reprint Management of suspected pulmonary embolism patients with low clinical and low V/Q probability
    Pierre Yves Salaun
    département de médecine interne et de pneumologie, Centre Hospitalier Universitaire de la Cavale Blanche, 29609 Brest Cedex, France
    Thromb Res 122:450-4. 2008
    ....
  14. ncbi request reprint Interrelation of hyperhomocysteinemia and inherited risk factors for venous thromboembolism. Results from the E.D.I.TH. study: a hospital-based case-control study
    Emmanuel Oger
    G E T B O EA 3878 Groupe d Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medicine and Chest Diseases, Brest University Hospital, 29609 Brest Cedex, France
    Thromb Res 120:207-14. 2007
    ..The hypothesis of an interaction between those risks has been raised and conflicting results were reported...
  15. doi request reprint Noninvasive diagnosis of pulmonary embolism
    Pierre Yves Salaun
    Universite Europeenne de Bretagne, Brest, France
    Chest 139:1294-8. 2011
    ..Diagnosis was based on clinical probability assessment, plasma D-dimer testing, then sequential testing to include lower limb venous compression ultrasonography, ventilation perfusion lung scan, and chest multidetector CT (MDCT) imaging...
  16. ncbi request reprint Fibrinogen Aalpha-Thr312Ala and factor XIII-A Val34Leu polymorphisms in idiopathic venous thromboembolism
    Gregoire Le Gal
    EA 3878, Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France
    Thromb Res 121:333-8. 2007
    ..However, clinical studies have yielded conflicting results on their possible association with venous thromboembolism (VTE)...
  17. ncbi request reprint V/Q SPECT interpretation for pulmonary embolism diagnosis: which criteria to use?
    Pierre Yves Le Roux
    Universite Europeenne de Bretagne, Brest, France
    J Nucl Med 54:1077-81. 2013
    ..Therefore, the aim of our study was to assess the performance of V/Q SPECT using various criteria for interpretation, in comparison with a validated independent diagnostic strategy...
  18. doi request reprint Site of venous thromboembolism and prothrombotic mutations according to body mass index. Results from the EDITH study
    Aurelien Delluc
    Université Européenne de Bretagne EA 3878, IFR 148, Universite de Brest, 29609 Brest, France
    Br J Haematol 154:486-91. 2011
    ..This study showed that BMI may play a role in determining the site of VTE and may interact with F2 G20210A but not with F5 G1691A for the risk of VTE...
  19. ncbi request reprint Management of suspected venous thromboembolism: the impact of a multifaceted intervention
    Pierre Yves Salaun
    Groupe d Etude de la Thrombose de Bretagne Occidentale GETBO, Hopital de la Cavale Blanche, F 29609 Brest Cedex, France
    Int J Qual Health Care 17:433-8. 2005
    ..To achieve a common strategy in the event of a suspected venous thromboembolism...
  20. ncbi request reprint Statins but not fibrates are associated with a reduced risk of venous thromboembolism: a hospital-based case-control study
    Karine Lacut
    Groupe d Etude de la Thrombose de Bretagne Occidentale GETBO, Department of Internal Medicine and Chest Diseases, Hopital de la Cavale Blanche, 29609 Brest Cedex, France
    Fundam Clin Pharmacol 18:477-82. 2004
    ..This possible protective effect of statins warrants further investigations...
  21. ncbi request reprint High prevalence of asymptomatic deep vein thrombosis on admission in a medical unit among elderly patients
    Emmanuel Oger
    Groupe d Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medecine and Chest Diseases, Hopital de la Cavale Blanche, F 29609 Brest Cedex, France
    Thromb Haemost 88:592-7. 2002
    ..5 to 32.6%) and 6.0 per 1,000 person-days (95% confidence interval, 0.0 to 12.7) among patients over 80 years. A high prevalence of asymptomatic deep vein thrombosis on admission was suggested particularly among elderly medical patients...
  22. ncbi request reprint Transthoracic sonography of the lung and pleura in view of a suspected pulmonary embolism: a pilot study
    Katia Mohn
    Groupe d Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medicine and Chest Diseases, Hopital de la Cavale Blanche, Brest, France
    J Ultrasound Med 22:673-8; quiz 680-1. 2003
    ..To evaluate the diagnostic performance of transthoracic sonography of the lung in view of an acute suspicion of pulmonary embolism...
  23. doi request reprint Increased thrombin generation measured in the presence of thrombomodulin in women with early pregnancy loss
    Luc De Saint Martin
    Department of Internal Medicine and Chest Diseases, Brest University Hospital, La Cavale Blanche Hospital, Brest, France
    Fertil Steril 95:1813-5.e1. 2011
    ..Adjusting age, protein S, factor VIII, factor V Leiden, and prothrombin G20210A did not change the results...
  24. doi request reprint Antipsychotic drugs and venous thromboembolism
    Cécile Tromeur
    Groupe d Etude de la Thrombose de Bretagne Occidentale, EA 3878, Department of Internal Medicine and Chest Diseases, Brest, France
    Thromb Res 130:S29-31. 2012
    ..Because of the level of uncertainty, the clinical impact on the prevention and the treatment of VTE in patients with a psychiatric illness appears to be low...
  25. doi request reprint [Pulmonary arterial hypertension in the elderly subject]
    I Frachon
    Equipe d accueil 3878, Groupe HTAP de Bretagne Occidentale GETBO, IFR 148, Universite de Brest, CHRU de Brest, 29609 Brest, France
    Rev Mal Respir 27:30-6. 2010
    ..To describe the features of pulmonary arterial hypertension (PAH) in elderly patients...
  26. ncbi request reprint Fatal congenital tuberculosis due to a Beijing strain in a premature neonate
    M L Abalain
    Laboratoire de Microbiologie, Centre Hospitalier Universitaire La Cavale Blanche, Boulevard Tanguy Prigent, and Faculté de Médecine et des Sciences de la Santé, Universite de Brest, 29609 Brest Cedex, France
    J Med Microbiol 59:733-5. 2010
    ..The infant died at 27 days old. A Beijing genotype strain of Mycobacterium tuberculosis was isolated both in the mother, from pulmonary and urine specimens, and in the infant, from peritoneal fluid...
  27. ncbi request reprint [Care of acute pulmonary embolism]
    C Gut-Gobert
    EA 3878, département de médecine interne et de pneumologie, Groupe d Etude de la Thrombose de Bretagne Occidentale, Hopital de la Cavale Blanche, CHU de Brest, Boulevard Tanguy Prigent, 29609 Brest Cedex, France
    Rev Pneumol Clin 64:298-304. 2008
    ..In addition, trials are currently under way in patients with a gloomier prognosis. The purpose is to validate or invalidate the indication of classic treatments (fibrinolysis) or new treatments (optional caval filters)...
  28. ncbi request reprint Chlamydia pneumoniae IgG serological status and venous thromboembolism: a cross-sectional hospital based study
    L de Saint Martin
    Internal Medicine and Chest Disease Department, University Hospital of Brest, France
    Presse Med 33:1493-6. 2004
    ..To search for a link between Chlamydia pneumoniae serological status and venous thromboembolic disease...
  29. ncbi request reprint Hyperhomocysteinemia and low B vitamin levels are independently associated with venous thromboembolism: results from the EDITH study: a hospital-based case-control study
    E Oger
    GETBO EA 3878 Groupe d Etude de la Thrombose de Bretagne Occidentale, Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France
    J Thromb Haemost 4:793-9. 2006
    ..Moderate hyperhomocysteinemia and B vitamins deficiency are thought to be risk factors for venous thromboembolism (VTE). The causality and independence of those associations are still questioned...
  30. ncbi request reprint Methylenetetrahydrofolate reductase C677T genotype and venous thromboembolic disease
    F Couturaud
    département de médecine interne et pneumologie, CHU de la Cavale Blanche, CHU Morvan, Brest, France
    Respiration 67:657-61. 2000
    ..Many studies have suggested an increased risk of venous thromboembolism (VTE) in patients with mild hyperhomocysteinemia. The C677T mutation in the MTHFR gene has recently been described as a cause of mild hyperhomocysteinemia...
  31. ncbi request reprint Association between antipsychotic drugs, antidepressant drugs and venous thromboembolism: results from the EDITH case-control study
    K Lacut
    EPI PHARM G E T B O, Equipe d accueil 3878, Department of Internal Medicine and Chest Diseases, Hopital de la Cavale Blanche, 29609 Brest Cedex, France
    Fundam Clin Pharmacol 21:643-50. 2007
    ..More studies are needed in order to further elucidate this adverse effect, and to determine the possible predisposing factors and the biological mechanisms involved...
  32. ncbi request reprint [Pulmonary embolism: the extent of computerized tomography]
    E Huchot
    Groupe d Etude de la Thrombose de Bretagne Occidentale, EA 38 78, CHU de la Cavale Blanche, Boulevard Tanguy Prigent, 29609 Brest Cedex, France
    Rev Pneumol Clin 64:276-81. 2008
    ..The confrontation between clinicians and radiologists is then all the more pertinent...
  33. ncbi request reprint Diagnosis and management of subsegmental pulmonary embolism
    G Le Gal
    Department of Internal Medicine and Chest Diseases, EA 3878 Groupe d Etude de la Thrombose de Bretagne Occidentale, Brest University Hospital, Brest, France
    J Thromb Haemost 4:724-31. 2006
    ..an accurate method to detect SSP embolism? How are subsegmental perfusion defects managed in outcome studies including spiral CT? What are the main characteristics and outcomes of patients in whom CT detects isolated subsegmental defects?..
  34. ncbi request reprint [Hypersensitivity pneumonitis in a patient taking pravastatin]
    N Liscoët-Loheac
    département de médecine interne et pneumologie, CHRU de la Cavale Blanche, 29609, Brest Cedex, France
    Rev Mal Respir 18:426-8. 2001
    ..The patient's syndromes gradually resolved with withdrawal of pravastatin. As HMG coenzyme A reductase inhibitors are commonly prescribed, any respiratory symptoms in this setting should be considered with special attention...
  35. doi request reprint Risk factors and clinical presentation of venous thromboembolism according to the age of relatives of patients with factor V Leiden
    Francis Couturaud
    Thromb Haemost 99:793-4. 2008
  36. ncbi request reprint Recurrent venous thromboembolism under anticoagulant therapy: a high risk in adenocarcinoma?
    Renaud Descourt
    Thromb Haemost 95:912-3. 2006
  37. ncbi request reprint Diagnostic value of D-dimer in patients with suspected pulmonary embolism: results from a multicentre outcome study
    Florence Parent
    Hopital Antoine Beclere, Assistance Publique Hopitaux de Paris, Clamart, France
    Thromb Res 120:195-200. 2007
    ..However, their role as an exclusionary first-line test is still uncertain, mainly because accuracy of the test varies according to the assay and the studied population...