Brigitte Boyer

Summary

Country: France

Publications

  1. ncbi request reprint Ras induces NBT-II epithelial cell scattering through the coordinate activities of Rac and MAPK pathways
    Natacha Edme
    Laboratoire de Régulations Cellulaires et Oncogénése UMR146, Institut Curie Section de Recherche, Centre Universitaire Paris Sud, 91405 Orsay, France
    J Cell Sci 115:2591-601. 2002
  2. ncbi request reprint Induction and regulation of epithelial-mesenchymal transitions
    B Boyer
    Laboratoire de Régulations cellulaires et Oncogénénese, UMR146 CNRS, Institut Curie Section de Recherche, Batiment 110, Centre Universitaire Paris Sud, 91405, Orsay Cedex, France
    Biochem Pharmacol 60:1091-9. 2000
  3. ncbi request reprint Src kinase contributes to the metastatic spread of carcinoma cells
    Brigitte Boyer
    UMR 146 CNRS, Institut Curie, Section de Recherche, Bâtiment 110 Centre Universitaire Paris Sud 91405 Orsay Cedex, France
    Oncogene 21:2347-56. 2002
  4. ncbi request reprint Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells
    Ana M Vallés
    Unité Mixte Recherche 146, Centre National de la Recherche Scientifique, Batiment 110, Centre Universitaire, 91405 Orsay, France
    J Biol Chem 279:44490-6. 2004

Collaborators

Detail Information

Publications4

  1. ncbi request reprint Ras induces NBT-II epithelial cell scattering through the coordinate activities of Rac and MAPK pathways
    Natacha Edme
    Laboratoire de Régulations Cellulaires et Oncogénése UMR146, Institut Curie Section de Recherche, Centre Universitaire Paris Sud, 91405 Orsay, France
    J Cell Sci 115:2591-601. 2002
    ..Finally, coexpression of active Rac1 and active MEK1 induced the motility of NBT-II cells, suggesting that Ras mediates NBT-II cell scattering through the coordinate activation of Rac and the Raf/MAPK pathway...
  2. ncbi request reprint Induction and regulation of epithelial-mesenchymal transitions
    B Boyer
    Laboratoire de Régulations cellulaires et Oncogénénese, UMR146 CNRS, Institut Curie Section de Recherche, Batiment 110, Centre Universitaire Paris Sud, 91405, Orsay Cedex, France
    Biochem Pharmacol 60:1091-9. 2000
    ..Understanding the mechanisms regulating EMT of normal and transformed epithelial cells may offer new perspectives for designing therapies for the treatment of metastatic cancers of epithelial origin...
  3. ncbi request reprint Src kinase contributes to the metastatic spread of carcinoma cells
    Brigitte Boyer
    UMR 146 CNRS, Institut Curie, Section de Recherche, Bâtiment 110 Centre Universitaire Paris Sud 91405 Orsay Cedex, France
    Oncogene 21:2347-56. 2002
    ..Altogether, these data demonstrate that Src activity correlates with the loss of epithelial differentiation concomitantly with the increase of the metastatic potential of carcinoma cells...
  4. ncbi request reprint Activation of Rac1 by paxillin-Crk-DOCK180 signaling complex is antagonized by Rap1 in migrating NBT-II cells
    Ana M Vallés
    Unité Mixte Recherche 146, Centre National de la Recherche Scientifique, Batiment 110, Centre Universitaire, 91405 Orsay, France
    J Biol Chem 279:44490-6. 2004
    ..Activation of the C3G/Rap1 signaling pathway resulted in down-regulation of the paxillin-Crk-DOCK180 complex and reduction of Rac1-GTP, suggesting that Rap1 activation could suppress the Rac1 signaling pathway in epithelial cells...