Didier Bouhassira

Summary

Country: France

Publications

  1. ncbi request reprint Comparison of the pain suppressive effects of clinical and experimental painful conditioning stimuli
    Didier Bouhassira
    INSERM E 332 Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, Boulogne Billancourt, France
    Brain 126:1068-78. 2003
  2. ncbi request reprint Investigation of the paradoxical painful sensation ('illusion of pain') produced by a thermal grill
    Didier Bouhassira
    INSERM E 332, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, AP HP, Boulogne and Université Versailles Saint Quentin, 92100 Boulogne Billancourt, France
    Pain 114:160-7. 2005
  3. ncbi request reprint Usefulness and limitations of quantitative sensory testing: clinical and research application in neuropathic pain states
    Per Hansson
    Dept of Neurosurgery, Pain Center, Karolinska University Hospital, 171 76 Stockholm, Sweden
    Pain 129:256-9. 2007
  4. ncbi request reprint Prevalence of chronic pain with neuropathic characteristics in the general population
    Didier Bouhassira
    INSERM U 792, Centre de Traitement et d Evaluation de la Douleur, CHU Ambroise Pare, 9, avenue Charles de Gaulle, Boulogne Billancourt cedex F 92100, France
    Pain 136:380-7. 2008
  5. pmc Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component
    Concepcion Perez
    Unit of Pain, Hospital de la Princesa, Madrid, Spain
    Health Qual Life Outcomes 5:66. 2007
  6. ncbi request reprint Development and validation of the Neuropathic Pain Symptom Inventory
    Didier Bouhassira
    INSERM E 332, Center d Evaluation t de Traitement de la Douleur, Hôspiat Ambroise paré, Boulogne Billancourt, France
    Pain 108:248-57. 2004
  7. ncbi request reprint Investigation of brainstem: descending pain modulation in animals and humans
    Didier Bouhassira
    INSERM E 332, CHU Ambroise Pare, AP HP Boulogne Billancourt, France
    Suppl Clin Neurophysiol 58:134-49. 2006
  8. ncbi request reprint Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)
    Didier Bouhassira
    INSERM E 332, AP HP Hôpital Ambroise Paré, Boulogne and Université Versailles Saint Quentin, France
    Pain 114:29-36. 2005
  9. doi request reprint Pharmacological dissection of the paradoxical pain induced by a thermal grill
    Delphine Kern
    INSERM U 792, Centre d Evaluation et de Traitement de la Douleur, CHU Ambroise Pare, 9, avenue Charles de Gaulle, Boulogne Billancourt F 92100, France
    Pain 135:291-9. 2008
  10. doi request reprint Effects of morphine on the experimental illusion of pain produced by a thermal grill
    Delphine Kern
    INSERM U, Centre d Evaluation et de Traitement de la Douleur, CHU Ambroise Pare, Boulogne Billancourt, France
    Pain 139:653-9. 2008

Collaborators

Detail Information

Publications43

  1. ncbi request reprint Comparison of the pain suppressive effects of clinical and experimental painful conditioning stimuli
    Didier Bouhassira
    INSERM E 332 Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, Boulogne Billancourt, France
    Brain 126:1068-78. 2003
    ..Thus, the mechanisms of counterirritation are not univocal, but depend on the pathophysiological mechanisms of clinical pain...
  2. ncbi request reprint Investigation of the paradoxical painful sensation ('illusion of pain') produced by a thermal grill
    Didier Bouhassira
    INSERM E 332, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, AP HP, Boulogne and Université Versailles Saint Quentin, 92100 Boulogne Billancourt, France
    Pain 114:160-7. 2005
    ..These results suggest that pain can be the result of a simple addition of non-noxious warm and cold signals...
  3. ncbi request reprint Usefulness and limitations of quantitative sensory testing: clinical and research application in neuropathic pain states
    Per Hansson
    Dept of Neurosurgery, Pain Center, Karolinska University Hospital, 171 76 Stockholm, Sweden
    Pain 129:256-9. 2007
  4. ncbi request reprint Prevalence of chronic pain with neuropathic characteristics in the general population
    Didier Bouhassira
    INSERM U 792, Centre de Traitement et d Evaluation de la Douleur, CHU Ambroise Pare, 9, avenue Charles de Gaulle, Boulogne Billancourt cedex F 92100, France
    Pain 136:380-7. 2008
    ..We identified distinctive socio-demographic profile and clinical features indicating that chronic pain with neuropathic characteristics is a specific health problem...
  5. pmc Validity and reliability of the Spanish version of the DN4 (Douleur Neuropathique 4 questions) questionnaire for differential diagnosis of pain syndromes associated to a neuropathic or somatic component
    Concepcion Perez
    Unit of Pain, Hospital de la Princesa, Madrid, Spain
    Health Qual Life Outcomes 5:66. 2007
    ..This study assesses the validity and reliability of the Spanish version of DN4 questionnaire as a tool for differential diagnosis of pain syndromes associated to a neuropathic (NP) or somatic component (non-neuropathic pain, NNP)...
  6. ncbi request reprint Development and validation of the Neuropathic Pain Symptom Inventory
    Didier Bouhassira
    INSERM E 332, Center d Evaluation t de Traitement de la Douleur, Hôspiat Ambroise paré, Boulogne Billancourt, France
    Pain 108:248-57. 2004
    ....
  7. ncbi request reprint Investigation of brainstem: descending pain modulation in animals and humans
    Didier Bouhassira
    INSERM E 332, CHU Ambroise Pare, AP HP Boulogne Billancourt, France
    Suppl Clin Neurophysiol 58:134-49. 2006
  8. ncbi request reprint Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)
    Didier Bouhassira
    INSERM E 332, AP HP Hôpital Ambroise Paré, Boulogne and Université Versailles Saint Quentin, France
    Pain 114:29-36. 2005
    ..The 10-item questionnaire developed in the present study constitutes a new diagnostic instrument, which might be helpful both in clinical research and daily practice...
  9. doi request reprint Pharmacological dissection of the paradoxical pain induced by a thermal grill
    Delphine Kern
    INSERM U 792, Centre d Evaluation et de Traitement de la Douleur, CHU Ambroise Pare, 9, avenue Charles de Gaulle, Boulogne Billancourt F 92100, France
    Pain 135:291-9. 2008
    ..This paradoxical pain, which involves the glutamatergic systems, acting through the NMDA receptors, but not the tonic endogenous opioids systems, might share some mechanisms with pathological pain...
  10. doi request reprint Effects of morphine on the experimental illusion of pain produced by a thermal grill
    Delphine Kern
    INSERM U, Centre d Evaluation et de Traitement de la Douleur, CHU Ambroise Pare, Boulogne Billancourt, France
    Pain 139:653-9. 2008
    ..This unique experimental "illusion of pain" may represent a new model to test analgesics in healthy volunteers...
  11. doi request reprint Long-term maintenance of the analgesic effects of transcranial magnetic stimulation in fibromyalgia
    Alaa Mhalla
    INSERM U 987, CHU Ambroise Pare, Assistance Publique Hopitaux de Paris, Boulogne Billancourt F 92100, France
    Pain 152:1478-85. 2011
    ..In conclusion, these results suggest that TMS may be a valuable and safe new therapeutic option in patients with fibromyalgia...
  12. doi request reprint Are psychological predictors of chronic postsurgical pain dependent on the surgical model? A comparison of total knee arthroplasty and breast surgery for cancer
    Anne Masselin-Dubois
    INSERM U 987, Boulogne Billancourt, France
    J Pain 14:854-64. 2013
    ..Thus, state anxiety and pain magnification seem to constitute psychological risk factors for chronic postsurgical pain relevant in all surgical models...
  13. doi request reprint The neuropathic components of chronic low back pain: a prospective multicenter study using the DN4 Questionnaire
    Nadine Attal
    INSERM U 987, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, APHP, Boulogne Billancourt, France
    J Pain 12:1080-7. 2011
    ....
  14. doi request reprint Unilateral repetitive transcranial magnetic stimulation of the motor cortex does not affect cognition in patients with fibromyalgia
    Sophie Baudic
    INSERM U 987, CHU Ambroise Pare, Assistance Publique Hopitaux de Paris, 92100 Boulogne Billancourt, France
    J Psychiatr Res 47:72-7. 2013
    ..Unilateral rTMS of the motor cortex over a three-month period did not modify cognitive functions in patients with chronic pain. rTMS may have mild beneficial cognitive effects, but confirmation is required in larger groups of patients...
  15. doi request reprint Alteration of cortical excitability in patients with fibromyalgia
    Alaa Mhalla
    INSERM U 987, CHU Ambroise Pare, APHP, Boulogne Billancourt, France
    Pain 149:495-500. 2010
    ..Our data add to the growing body of evidence for objective and quantifiable changes in brain function in fibromyalgia...
  16. doi request reprint Functional brain imaging of trigeminal neuralgia
    Xavier Moisset
    INSERM U 987, Physiopathologie et Pharmacologie Clinique de la Douleur, Hopital Ambroise Pare, Boulogne Billancourt F 92100, France
    Eur J Pain 15:124-31. 2011
    ..ACC). The fact that large portions of the classical 'pain neuromatrix' were also activated during nonpainful stimulation of the trigger zone, could reflect a state of maintained sensitization of the trigeminal nociceptive systems in CTN...
  17. doi request reprint Development and validation of the Fibromyalgia Rapid Screening Tool (FiRST)
    Serge Perrot
    INSERM U 987, Hopital Ambroise Pare, Boulogne Billancourt, F 92100, France
    Pain 150:250-6. 2010
    ..7%. In conclusion, FiRST is a brief, simple and straightforward self-administered questionnaire with excellent discriminative value, of potential value for the detection of fibromyalgia in both daily practice and clinical research...
  18. doi request reprint Neuropharmacological basis of rTMS-induced analgesia: the role of endogenous opioids
    Daniel Ciampi de Andrade
    Centre d Evaluation et de Traitement de la Douleur, Ambroise Paré, Boulogne Billancourt, France
    Pain 152:320-6. 2011
    ..Endogenous opioids are shown to be involved in the analgesic effects of repetitive transcranial magnetic stimulation of the motor cortex...
  19. pmc Constitutive cyclooxygenase-2 is involved in central nociceptive processes in humans
    Frederic Martin
    Institut National de la Santé et de la Recherche Médicale INSERM U 792, centre hospitalier universitaire Ambroise Paré, Centre d Evaluation et de Traitement de la Douleur, Assistance Publique Hopitaux de Paris AP HP, Boulogne Billancourt, France
    Anesthesiology 106:1013-8. 2007
    ..The current study aimed to investigate the role of constitutive COX-2 in the spinal transmission of nociceptive signals in humans...
  20. doi request reprint Clinical, functional and structural determinants of central pain in syringomyelia
    Samar M Hatem
    INSERM U 987, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, 9 avenue Charles de Gaulle, 92100 Boulogne Billancourt, France
    Brain 133:3409-22. 2010
    ....
  21. ncbi request reprint Brain imaging of neuropathic pain
    Xavier Moisset
    INSERM U 792, Centre de Traitement et d Evaluation de la Douleur, CHU Ambroise Pare, 9, avenue Charles de Gaulle, 92100 Boulogne Billancourt cedex, France
    Neuroimage 37:S80-8. 2007
    ..Overall, these studies indicated that acute physiological pain and neuropathic pain have distinct although overlapping brain activation pattern, but that there is no unique "pain matrix" or "allodynia network"...
  22. doi request reprint Patient perspective on herpes zoster and its complications: an observational prospective study in patients aged over 50 years in general practice
    Didier Bouhassira
    Inserm U987, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, Boulogne Billancourt F 92100, France
    Pain 153:342-9. 2012
    ..Despite early diagnosis and treatment with antiviral agents, many patients with herpes zoster experience persistent pain and marked long-term reduction in health-related quality of life...
  23. doi request reprint Diffuse analgesic effects of unilateral repetitive transcranial magnetic stimulation (rTMS) in healthy volunteers
    Frédéric Nahmias
    INSERM U 987, Physiopathologie et Pharmacologie Clinique de la Douleur, CHU Ambroise Pare, APHP, Boulogne Billancourt, France
    Pain 147:224-32. 2009
    ..The lack of effect on the RIII reflex suggests that such analgesic effects may not depend on the activation of descending inhibitory systems...
  24. ncbi request reprint Psychophysical study of the effects of topical application of menthol in healthy volunteers
    Samar Hatem
    INSERM, U792, CHU Ambroise Pare, AP HP, Boulogne Billancourt F 92100, France
    Pain 122:190-6. 2006
    ..These data suggest that 30% menthol application may be a useful experimental model for studies of cold hyperalgesia in humans. The absence of local skin reactions also makes this test potentially suitable for use in patients...
  25. ncbi request reprint Translating basic research on sodium channels in human neuropathic pain
    Nadine Attal
    Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, AP HP and Université Versailles Saint Quentin, France
    J Pain 7:S31-7. 2006
    ..Studies using more selective sodium channel blockers are required to gain further insight into the role of the various subtypes of sodium channel in these pain conditions...
  26. pmc Chronic pain with neuropathic characteristics in diabetic patients: a French cross-sectional study
    Didier Bouhassira
    INSERM U 987, Centre d evaluation et traitement de la douleur, CHU Ambroise Pare, APHP, Boulogne Billancourt, France Université Versailles Saint Quentin, Versailles, France
    PLoS ONE 8:e74195. 2013
    ..Our aim was to estimate the prevalence of distal chronic pain with neuropathic characteristics in patients with type 1 and type 2 diabetes mellitus and its impact on quality of life, mood, anxiety, sleep and healthcare utilization...
  27. doi request reprint Anatomical connections between brain areas activated during rectal distension in healthy volunteers: a visceral pain network
    Xavier Moisset
    Inserm U792, Physiopathologie et Pharmacologie Clinique de la Douleur, Hopital Ambroise Pare, 92100 Boulogne, France
    Eur J Pain 14:142-8. 2010
    ..e. ACC, thalamus, S1, S2 and PFC. The combined use of fMRI and DTI in healthy subjects during rectal distension revealed a neural network of visceral sensory perception involving the insula, thalamus, somatosensory cortices, ACC and PFC...
  28. pmc Adherence of French GPs to chronic neuropathic pain clinical guidelines: results of a cross-sectional, randomized, "e" case-vignette survey
    Valéria Martinez
    Anesthésiologie Réanimation, Hopital Raymond Poincare, Garches, France INSERM U 987, Centre d Evaluation et de Traitement de la Douleur, CHU Ambroise Pare, Boulogne Billancourt, France
    PLoS ONE 9:e93855. 2014
    ..The French Pain Society published guidelines for neuropathic pain management in 2010. Our aim was to evaluate the compliance of GPs with these guidelines three years later...
  29. doi request reprint Risk factors predictive of chronic postsurgical neuropathic pain: the value of the iliac crest bone harvest model
    Valéria Martinez
    Service d Anesthésie Réanimation Chirurgicale, Hopital Raymond Poincare, Assistance Publique Hopitaux de Paris, 104 boulevard Raymond Poincaré, F 92380 Garches, France
    Pain 153:1478-83. 2012
    ..02; P=.004) and DN4 score (odds ratio 1.94; P=.001). These findings suggest that both nerve lesions and central sensitization are involved in CPSNP development and could be seen as early warning signs...
  30. ncbi request reprint [Management of chronic pain in the future]
    Didier Bouhassira
    Inserm U987, Centre d Evaluation et de Traitement de la Douleur, Hopital Ambroise Pare, AP HP, 92100 Boulogne Billancourt, France
    Rev Prat 63:813-5. 2013
    ..The variety of new treatment options should allow a more efficacious management of chronic pain, taylored to each patient's profile...
  31. doi request reprint [Definition and classification of neuropathic pain]
    Didier Bouhassira
    INSERM U 792, F 92100 Boulogne Billancourt, France
    Presse Med 37:311-4. 2008
    ..These two types of pain are nonetheless frequently found in the same patient. It is important to be able to recognize neuropathic pain, either isolated or associated with other chronic pain, because it requires appropriate management...
  32. pmc The evolution of primary hyperalgesia in orthopedic surgery: quantitative sensory testing and clinical evaluation before and after total knee arthroplasty
    Valéria Martinez
    Department of Anesthesia, Assistance Publique Hopitaux de Paris, Hopital Raymond Poincare, Garches, France
    Anesth Analg 105:815-21. 2007
    ..Quantitative sensory testing (QST) allows precise characterization of sensory deficits and painful symptoms and may offer additional information on the pathophysiology of postoperative pain...
  33. ncbi request reprint Mechanisms of central neuropathic pain: a combined psychophysical and fMRI study in syringomyelia
    Denis Ducreux
    Department of Neuroradiology, CHU Kremlin Bicêtre, AP HP, Hôpital Kremlin Bicêtre, Kremlin Bicetre, France
    Brain 129:963-76. 2006
    ..The prefrontal cortex was the only area consistently activated by pathological evoked pains, suggesting that alteration of high-level pain modulatory mechanisms might play a major role in allodynia due to central lesion...
  34. pmc Conceptual adequacy of the neuropathic pain symptom inventory in six countries
    Bruce Crawford
    Mapi Values, 15 Court Square, Suite 620, Boston, MA 02108, USA
    Health Qual Life Outcomes 6:62. 2008
    ....
  35. ncbi request reprint Can pain be more or less neuropathic?
    Nadine Attal
    Pain 110:510-1. 2004
  36. ncbi request reprint Towards a new taxonomy of idiopathic orofacial pain
    Alain Woda
    EA 3847, Faculte de Chirurgie Dentaire, CHU Clermont Ferrand 63000, France
    Pain 116:396-406. 2005
    ..These data provide grounds for an evidence-based classification of idiopathic facial pain entities and indicate that the current sub-classification of these syndromes relies primarily on the topography of the symptoms...
  37. ncbi request reprint [Pain and irritable bowel syndrome]
    Benoit Coffin
    Service d Hepato Gastroenterologie, AP HP Hôpital Louis Mourier, 178 rue des Renouillers, 92700 Colombes
    Gastroenterol Clin Biol 29:769-71. 2005
  38. ncbi request reprint Interaction of a combination of morphine and ketamine on the nociceptive flexion reflex in human volunteers
    Anne Elisabeth Bossard
    Centre d Evaluation et de Traitement de la Douleur et Service d Anesthésie Réanimation, Chirurgicale Hôpital Ambroise Paré, 92104 Boulogne, France
    Pain 98:47-57. 2002
    ....
  39. ncbi request reprint Using screening tools to identify neuropathic pain
    Michael I Bennett
    Clinical Teaching and Research Unit, St Gemma s Hospice, 329 Harrogate Road, Leeds LS17 6QD, UK
    Pain 127:199-203. 2007
  40. ncbi request reprint Epidemiology of neuropathic pain: can we use the screening tools?
    Michael I Bennett
    Pain 132:12-3. 2007
  41. pmc Antiinflammatory effect of peripheral nerve blocks after knee surgery: clinical and biologic evaluation
    Frederic Martin
    Service d Anesthésie, Assistance Publique Hopitaux de Paris, Hopital Raymond Poincare, Garches, France
    Anesthesiology 109:484-90. 2008
    ..Nerve blocks provide analgesia after surgery. The authors tested whether nerve blocks have antiinflammatory effects...
  42. pmc Lack of impact of intravenous lidocaine on analgesia, functional recovery, and nociceptive pain threshold after total hip arthroplasty
    Frederic Martin
    Service Pharmacologie Toxicologie, Assistance Publique Hopitaux de Paris, Hopital Raymond Poincare, Garches, France
    Anesthesiology 109:118-23. 2008
    ..This study aimed to evaluate whether a continuous intravenous low-dose lidocaine infusion reduced postoperative pain and modified nociceptive pain threshold after total hip arthroplasty...
  43. doi request reprint Chronic pain in Parkinson's disease: the cross-sectional French DoPaMiP survey
    Laurence Negre-Pages
    Department of Clinical Pharmacology, University Hospital, Toulouse, France
    Mov Disord 23:1361-9. 2008
    ..9; 95% CI 1.2-3.2). Chronic pain is frequent but underreported in PD. Awareness of this problem should be increased and the assessment of analgesic strategies improved...