Carole Bougault

Summary

Country: France

Publications

  1. ncbi request reprint Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish
    Jérôme Gouttenoire
    Universite de Lyon, Lyon, F 69003, Universite Lyon 1, CNRS UMR5086, Institut de Biologie et Chimie des Proteines, IFR 128 Biosciences Gerland Lyon Sud, 7 passage du Vercors, Lyon F 69367, France
    J Biol Chem 282:30960-73. 2007
  2. pmc Molecular analysis of chondrocytes cultured in agarose in response to dynamic compression
    Carole Bougault
    UMR 5086, CNRS, Universite de Lyon, IFR 128, IBCP, Institut de Biologie et Chimie des Proteines, 7 passage du Vercors F 69367 Lyon FRANCE
    BMC Biotechnol 8:71. 2008
  3. doi request reprint Investigating conversion of mechanical force into biochemical signaling in three-dimensional chondrocyte cultures
    Carole Bougault
    UMR5086, CNRS, IFR128, IBCP Institut de Biologie et Chimie des Protéines, Universite de Lyon, Lyon, France
    Nat Protoc 4:928-38. 2009
  4. pmc Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes
    Carole Bougault
    Universite Lyon 1, Univ Lyon, CNRS, FRE 3310 Dysfonctionnement de l Homéostasie Tissulaire et Ingénierie Thérapeutique, IBCP, Lyon, France
    PLoS ONE 7:e36964. 2012
  5. pmc BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes
    Jérôme Gouttenoire
    Institut de Biologie et Chimie des Proteines, CNRS UMR 5086, Universite de Lyon, and IFR 128 BioSciences Gerland Lyon Sud, 7 passage du Vercors, Lyon F 69367, France
    Eur J Cell Biol 89:307-14. 2010
  6. doi request reprint Alteration of cartilage mechanical properties in absence of β1 integrins revealed by rheometry and FRAP analyses
    Carole Bougault
    Institut de Biologie et Chimie des Proteines, FRE3310 CNRS, Universite de Lyon, 7 passage du Vercors, F 69367 Lyon Cedex 07, France
    J Biomech 46:1633-40. 2013

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish
    Jérôme Gouttenoire
    Universite de Lyon, Lyon, F 69003, Universite Lyon 1, CNRS UMR5086, Institut de Biologie et Chimie des Proteines, IFR 128 Biosciences Gerland Lyon Sud, 7 passage du Vercors, Lyon F 69367, France
    J Biol Chem 282:30960-73. 2007
    ..Thus our results taken together indicate that the ciliary protein IFT46 has a specific function in chondrocytes and is also essential for normal development of vertebrates...
  2. pmc Molecular analysis of chondrocytes cultured in agarose in response to dynamic compression
    Carole Bougault
    UMR 5086, CNRS, Universite de Lyon, IFR 128, IBCP, Institut de Biologie et Chimie des Proteines, 7 passage du Vercors F 69367 Lyon FRANCE
    BMC Biotechnol 8:71. 2008
    ..The mouse model is of particular interest because of the availability of a large choice of bio-molecular tools suitable to study it, as well as genetically modified mice...
  3. doi request reprint Investigating conversion of mechanical force into biochemical signaling in three-dimensional chondrocyte cultures
    Carole Bougault
    UMR5086, CNRS, IFR128, IBCP Institut de Biologie et Chimie des Protéines, Universite de Lyon, Lyon, France
    Nat Protoc 4:928-38. 2009
    ..The protocols can be carried out with a limited number of mouse embryos or newborns and this point is particularly important regarding genetically modified mice...
  4. pmc Dynamic compression of chondrocyte-agarose constructs reveals new candidate mechanosensitive genes
    Carole Bougault
    Universite Lyon 1, Univ Lyon, CNRS, FRE 3310 Dysfonctionnement de l Homéostasie Tissulaire et Ingénierie Thérapeutique, IBCP, Lyon, France
    PLoS ONE 7:e36964. 2012
    ..Furthermore, modulation of transcripts corresponding to different aspects of cellular physiology was observed, such as non-coding RNAs or primary cilium. This study provides new insight into how chondrocytes respond to mechanical forces...
  5. pmc BMP-2 and TGF-beta1 differentially control expression of type II procollagen and alpha 10 and alpha 11 integrins in mouse chondrocytes
    Jérôme Gouttenoire
    Institut de Biologie et Chimie des Proteines, CNRS UMR 5086, Universite de Lyon, and IFR 128 BioSciences Gerland Lyon Sud, 7 passage du Vercors, Lyon F 69367, France
    Eur J Cell Biol 89:307-14. 2010
    ..This result strongly suggests that signaling pathways other than Smad proteins are involved in the effect of BMP-2 on type II procollagen expression...
  6. doi request reprint Alteration of cartilage mechanical properties in absence of β1 integrins revealed by rheometry and FRAP analyses
    Carole Bougault
    Institut de Biologie et Chimie des Proteines, FRE3310 CNRS, Universite de Lyon, 7 passage du Vercors, F 69367 Lyon Cedex 07, France
    J Biomech 46:1633-40. 2013
    ..In this study, we aimed to determine the role of the transmembrane β1 integrin adhesion receptors in cartilage biomechanical properties by the use of genetic modification in mice...