Karim Boudjema

Summary

Country: France

Publications

  1. doi request reprint A simple system to predict perihilar cholangiocarcinoma resectability
    Karim Boudjema
    Service de chirurgie hépatobiliaire et digestive, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, Rennes, France
    J Gastrointest Surg 17:1247-56. 2013
  2. doi request reprint Efficacy and safety of Celsior preservation fluid in liver transplantation: one-year follow up of a prospective, multicenter, non-randomized study
    Karim Boudjema
    Service de chirurgie hépatobiliaire et digestive, Hopital de Pontchaillou, Centre Hospitalier Universitaire de Rennes and Université de Rennes 1, Rennes, France
    Clin Transplant 26:199-207. 2012
  3. ncbi request reprint [Liver transplantation for hepatocellular carcinoma]
    Karim Boudjema
    Département de chirurgie viscérale, Hopital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes cedex 09, France
    Cancer Radiother 9:458-63. 2005
  4. ncbi request reprint [Two tapes to control the main fissure of the liver]
    K Boudjema
    Département de chirurgie viscérale, unité de chirurgie hépatobiliaire et transplantation hépatique, Hopital Pontchaillou, 35033 Rennes, France
    Ann Chir 127:149-53. 2002
  5. doi request reprint Reduced-dose tacrolimus with mycophenolate mofetil vs. standard-dose tacrolimus in liver transplantation: a randomized study
    K Boudjema
    Service de chirurgie hépatobiliaire et digestive, Hopital de Pontchaillou, Centre Hospitalier Universitaire, Rennes, France
    Am J Transplant 11:965-76. 2011
  6. ncbi request reprint [Surgical exposure of visceral arteries]
    E Kieffer
    Service de Chirurgie Vasculaire, Centre Hospitalier Universitaire Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Ann Chir 129:46-51. 2004
  7. doi request reprint Liver transplantation avoided in patients with fulminant hepatic failure who received albumin dialysis with the molecular adsorbent recirculating system while on the waiting list: impact of the duration of therapy
    Christophe Camus
    Infectious Diseases and Intensive Care Medicine, Pontchaillou Hospital, Rennes, France
    Ther Apher Dial 13:549-55. 2009
  8. doi request reprint Liver transplantation for hepatocellular carcinoma without preoperative tumor biopsy
    Philippe Compagnon
    Service de Chirurgie Hépato biliaire et Digestive, Hopital Pontchaillou, INSERM U522, Universite Rennes 1, Rennes, France
    Transplantation 86:1068-76. 2008
  9. doi request reprint Does an aberrant right hepatic artery really influence the short- and long-term results of a pancreaticoduodenectomy for malignant disease? A matched case-controlled study
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France INSERM, UMR991, Foie, Métabolismes et Cancer, Universite de Rennes 1, Rennes, France Electronic address
    J Surg Res 185:620-5. 2013
  10. ncbi request reprint Intra-arterial injection of iodine-131-labeled lipiodol for treatment of hepatocellular carcinoma
    Eveline Boucher
    Department of Medical Oncology, Centre Eugene Marquis, Rennes, France
    Radiother Oncol 82:76-82. 2007

Collaborators

Detail Information

Publications42

  1. doi request reprint A simple system to predict perihilar cholangiocarcinoma resectability
    Karim Boudjema
    Service de chirurgie hépatobiliaire et digestive, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, Rennes, France
    J Gastrointest Surg 17:1247-56. 2013
    ..When the LLC is invaded, vascular invasion is frequent and radical resection might often be impossible without complex vascular reconstruction...
  2. doi request reprint Efficacy and safety of Celsior preservation fluid in liver transplantation: one-year follow up of a prospective, multicenter, non-randomized study
    Karim Boudjema
    Service de chirurgie hépatobiliaire et digestive, Hopital de Pontchaillou, Centre Hospitalier Universitaire de Rennes and Université de Rennes 1, Rennes, France
    Clin Transplant 26:199-207. 2012
    ..Comparison with ELTR patients suggested that liver allograft survival was similar using Celsior or UW solution for preservation of unselected donor grafts...
  3. ncbi request reprint [Liver transplantation for hepatocellular carcinoma]
    Karim Boudjema
    Département de chirurgie viscérale, Hopital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes cedex 09, France
    Cancer Radiother 9:458-63. 2005
    ..The role of chemoembolisation, liver resection and thermal ablation while the patient is waiting for a graft remains debatable...
  4. ncbi request reprint [Two tapes to control the main fissure of the liver]
    K Boudjema
    Département de chirurgie viscérale, unité de chirurgie hépatobiliaire et transplantation hépatique, Hopital Pontchaillou, 35033 Rennes, France
    Ann Chir 127:149-53. 2002
    ..The two tapes technique cannot be applied when liver is fibrotic or when biliary ducts are dilated...
  5. doi request reprint Reduced-dose tacrolimus with mycophenolate mofetil vs. standard-dose tacrolimus in liver transplantation: a randomized study
    K Boudjema
    Service de chirurgie hépatobiliaire et digestive, Hopital de Pontchaillou, Centre Hospitalier Universitaire, Rennes, France
    Am J Transplant 11:965-76. 2011
    ..Reduced-dose tacrolimus with mycophenolate mofetil reduces the occurrence of renal dysfunction and the risk of graft rejection. This immunosuppressive regimen could replace full-dose tacrolimus in adult liver transplantation...
  6. ncbi request reprint [Surgical exposure of visceral arteries]
    E Kieffer
    Service de Chirurgie Vasculaire, Centre Hospitalier Universitaire Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Ann Chir 129:46-51. 2004
    ..Surgery of visceral arteries is mainly indicated for ostial and juxtaostial atherosclerosis of the celiac axis and superior mesenteric arteries. Their surgical exposures are often difficult because of their deepness...
  7. doi request reprint Liver transplantation avoided in patients with fulminant hepatic failure who received albumin dialysis with the molecular adsorbent recirculating system while on the waiting list: impact of the duration of therapy
    Christophe Camus
    Infectious Diseases and Intensive Care Medicine, Pontchaillou Hospital, Rennes, France
    Ther Apher Dial 13:549-55. 2009
    ..A minimum duration of therapy (> or =15 h) could be necessary to expect significant liver function improvement...
  8. doi request reprint Liver transplantation for hepatocellular carcinoma without preoperative tumor biopsy
    Philippe Compagnon
    Service de Chirurgie Hépato biliaire et Digestive, Hopital Pontchaillou, INSERM U522, Universite Rennes 1, Rennes, France
    Transplantation 86:1068-76. 2008
    ..Progress in liver imaging has made pretransplantation tumor biopsy no longer systematic in patients with hepatocellular carcinoma (HCC)...
  9. doi request reprint Does an aberrant right hepatic artery really influence the short- and long-term results of a pancreaticoduodenectomy for malignant disease? A matched case-controlled study
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France INSERM, UMR991, Foie, Métabolismes et Cancer, Universite de Rennes 1, Rennes, France Electronic address
    J Surg Res 185:620-5. 2013
    ..The risk associated with ARHA during pancreaticoduodenectomy (PD) continues to be debated. The aim of this study was to compare the clinical outcomes and survival after PD with ARHA against a matched cohort of patients without ARHA...
  10. ncbi request reprint Intra-arterial injection of iodine-131-labeled lipiodol for treatment of hepatocellular carcinoma
    Eveline Boucher
    Department of Medical Oncology, Centre Eugene Marquis, Rennes, France
    Radiother Oncol 82:76-82. 2007
    ..We report, the results of an open study of this therapy in cirrhotic patients with small hepatocellular carcinoma...
  11. doi request reprint Chemotherapy for inoperable advanced or metastatic cholangiocarcinoma: retrospective analysis of 78 cases in a single center over four years
    Marc Pracht
    Medical Oncology Unit, Comprehensive Cancer Center Eugène Marquis, Rennes, France
    Chemotherapy 58:134-41. 2012
    ..According to phase II and III trials, regimens combining 5-fluorouracil (5FU) or gemcitabine with a platinum salt have provided an overall response rate of 12-50% with a median overall survival of 5-16 months...
  12. doi request reprint Volumetric changes after (90)y radioembolization for hepatocellular carcinoma in cirrhosis: an option to portal vein embolization in a preoperative setting?
    Julien Edeline
    Medical Oncology Department, Comprehensive Cancer Institute Eugène Marquis, Rennes, France
    Ann Surg Oncol 20:2518-25. 2013
    ..Contralateral hypertrophy after (90)Y radioembolization has been described in case reports, but the incidence and quantitative extent of liver volume modifications after this therapy are unknown...
  13. doi request reprint Role of preoperative optimization of the liver for resection in patients with hilar cholangiocarcinoma type III
    Stephane Grandadam
    Service de chirurgie hépatobiliaire et digestive, CHU Pontchaillou, Universite Rennes I, Rennes, France
    Ann Surg Oncol 17:3155-61. 2010
    ..Long-term survival after complete resection of hilar cholangiocarcinoma remains disappointing. The aim of this retrospective study was to assess the impact of liver optimization on postoperative outcome of hilar cholangiocarcinoma type III...
  14. doi request reprint Adjuvant intraarterial injection of 131I-labeled lipiodol after resection of hepatocellular carcinoma: progress report of a case-control study with a 5-year minimal follow-up
    Eveline Boucher
    Departement d Oncologie Medicale, Centre Eugene Marquis, Rennes, France
    J Nucl Med 49:362-6. 2008
    ..The goal of this paper is to update the 2003 results for a minimal follow-up of 5 y...
  15. doi request reprint First experience of hepatic radioembolization using microspheres labelled with yttrium-90 (TheraSphere): practical aspects concerning its implementation
    Etienne Garin
    Department of Nuclear Medicine, Comprehensive Cancer Center Eugène Marquis, Rennes, France
    Eur J Nucl Med Mol Imaging 37:453-61. 2010
    ..We report a first experience involving the use of (90)Y radiolabelled microspheres (TheraSphere) for the treatment of mainly primary hepatic tumours...
  16. ncbi request reprint Resection of hepatocellular carcinoma in noncirrhotic liver: analysis of risk factors for survival
    Eric Dupont-Bierre
    Centre Hospitalo Universitaire Pontchaillou, Rennes, France
    J Am Coll Surg 201:663-70. 2005
    ..The aim of this study was to identify factors predictive of survival after curative resection of hepatocellular carcinoma (HCC) in noncirrhotic liver...
  17. pmc Incidence and predictive factors of clinically relevant bile leakage in the modern era of liver resections
    Antoine Guillaud
    Service de chirurgie hépatobiliaire et digestive, Universite de Rennes, Rennes, France
    HPB (Oxford) 15:224-9. 2013
    ..To evaluate the incidence, the impact on survival and the predictive factors of bile leakage (BL) in a recent large monocentric series of liver resections performed in a referral tertiary care centre...
  18. doi request reprint Reperfusion stress induced during intermittent selective clamping accelerates rat liver regeneration through JNK pathway
    Hélène Duval
    INSERM U522, CHU Pontchaillou, rue Henri Le Guilloux, Rennes, France
    J Hepatol 52:560-9. 2010
    ..Here, we developed a rat model of selective lobe occlusion to isolate reperfusion stress from ischemia and to analyze its effect on liver regeneration...
  19. doi request reprint Severe left-sided heart failure early after liver transplantation
    Frederic Schnell
    Service de Cardiologie et Maladies Vasculaires Centre d Investigation Clinique Innovations Technologiques 804, Institut National de la Santé et de la Recherche Médicale Unité 642, Centre Hospitalier Universitaire Rennes, Rennes, France
    Liver Transpl 15:1296-305. 2009
    ..In conclusion, LHF after LT carries a high mortality risk and may have different causes. Except for immediate postoperative cases, an infection and an elevated MELD score appear to be determinant...
  20. doi request reprint Intrahepatic cholangiocarcinoma: impact of genetic hemochromatosis on outcome and overall survival after surgical resection
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Surg Res 180:56-61. 2013
    ..The influence of genetic hemochromatosis (GH) on outcomes following surgical resections for intrahepatic cholangiocarcinoma (ICC) has not been evaluated...
  21. doi request reprint Impact of age over 75 years on outcomes after pancreaticoduodenectomy
    Laurent Sulpice
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Surg Res 178:181-7. 2012
    ..The aim of our study was to assess the incidence of death and postoperative complications following PD and identify the risk factors in patients >75 y...
  22. pmc Pretreatment with mangafodipir improves liver graft tolerance to ischemia/reperfusion injury in rat
    Ismail Ben Mosbah
    INSERM, UMR991, Foie, Métabolismes et Cancer, CHU Pontchaillou, Rennes, France
    PLoS ONE 7:e50235. 2012
    ..Since MnDPDP is safely used in liver imaging, this preservation strategy holds great promise for translation to clinical liver transplantation...
  23. doi request reprint Colorectal cancer with synchronous liver metastases: does global management at the same centre improve results?
    Bernard Faber
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire de Rennes, Universite de Rennes 1, 2, rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
    Clin Res Hepatol Gastroenterol 37:56-63. 2013
    ..Synchronous liver metastases (SLM) occur in 20% of colorectal cancers (CRC). Resection of SLM and CLC can be undertaken at different centres (separate management, SM) or at the same centre (global management, GM)...
  24. ncbi request reprint Association of cisplatin and intra-arterial injection of 131I-lipiodol in treatment of hepatocellular carcinoma: results of phase II trial
    Jean Luc Raoul
    Department of Medical Oncology, Centre E Marquis, Rennes, France
    Int J Radiat Oncol Biol Phys 64:745-50. 2006
    ..The efficacy and tolerance of intra-arterial injections of 131I-Lip combined with systemic cisplatin was tested in a phase II trial...
  25. doi request reprint Molecular profiling of stroma identifies osteopontin as an independent predictor of poor prognosis in intrahepatic cholangiocarcinoma
    Laurent Sulpice
    INSERM, UMR991, Liver Metabolisms and Cancer, Rennes, France Université de Rennes 1, Rennes, France CHU Rennes, Service de chirurgie hépatobiliaire et digestive, Rennes, France
    Hepatology 58:1992-2000. 2013
    ..More important, multivariate analysis demonstrated that the stromal expression of osteopontin was an independent prognostic marker for overall and disease-free survival...
  26. doi request reprint MELD-based graft allocation system fails to improve liver transplantation efficacy in a single-center intent-to-treat analysis
    Vianney Bouygues
    Service de chirurgie hépatobiliaire et digestive, Universite de Rennes 1, Hopital Pontchaillou, Centre Hospitalier Universitaire de Rennes, Rennes, France
    Clin Res Hepatol Gastroenterol 36:464-72. 2012
    ..Since March 2007, priority access to liver transplantation in France has been given to patients with the highest MELD scores...
  27. doi request reprint Effect of an anesthesia with propofol compared with desflurane on free radical production and liver function after partial hepatectomy
    Bruno Laviolle
    Service de Pharmacologie Clinique, Hopital de Pontchaillou, CHU de Rennes, Universite de Rennes 1, 35033 Rennes Cedex, France
    Fundam Clin Pharmacol 26:735-42. 2012
    ..Our study showed that in patients undergoing partial hepatectomy, propofol did not reduce MDA formation but seemed to display a protective effect on hepatic damages and liver function when compared to desflurane...
  28. ncbi request reprint Molecular adsorbent recirculating system dialysis in patients with acute liver failure who are assessed for liver transplantation
    Christophe Camus
    Service de Maladies Infectieuses et Reanimation Medicale, Hopital Pontchaillou, rue Henri Le Guilloux, CHRU, 2, 35033, Rennes Cedex, France
    Intensive Care Med 32:1817-25. 2006
    ..To assess the usefulness of dialysis with the molecular adsorbent recirculating system (MARS) in patients with acute liver failure who fulfil criteria for liver transplantation...
  29. doi request reprint Aminobisphosphonate-pretreated dendritic cells trigger successful Vgamma9Vdelta2 T cell amplification for immunotherapy in advanced cancer patients
    Florian Cabillic
    EE341 Biothérapies Innovantes, Faculte de Medecine, Universite de Rennes 1, Rennes, France
    Cancer Immunol Immunother 59:1611-9. 2010
    ..Thus, this method of generating Vgamma9Vdelta2 T cells leads eligible for Vgamma9Vdelta2 T cell adoptive immunotherapy the HCC and mCRC patients...
  30. ncbi request reprint Adjuvant intra-arterial injection of iodine-131-labeled lipiodol after resection of hepatocellular carcinoma
    Eveline Boucher
    Départements d Oncologie Médicale, Rennes, France
    Hepatology 38:1237-41. 2003
    ..A randomized study including more patients would be necessary to confirm its contribution to therapeutic management...
  31. doi request reprint Enteral nutrition reduces delayed gastric emptying after standard pancreaticoduodenectomy with child reconstruction
    Michel Rayar
    Service de chirurgie hépatobiliaire et digestive, Hopital Pontchaillou, Centre Hospitalier Universitaire, Universite de Rennes 1, Rennes, France
    J Gastrointest Surg 16:1004-11. 2012
    ..Our retrospective study aimed to evaluate the influence of enteral nutrition (EN) on DGE incidence after standard PD with antrectomy and Child reconstruction...
  32. ncbi request reprint Improved liver function and decreased hepatitis C viral load after tacrolimus was replaced by cyclosporine
    R Lorho
    Department of Liver Disease, CHU Pontchaillou, Rennes, France
    Transplant Proc 37:2871-2. 2005
    ..Then, due to a lack of virological and biochemical response, tacrolimus was replaced by cyclosporine (Neoral), while maintaining the same antiviral therapy. Decreases in the viral load and transaminases levels were observed...
  33. ncbi request reprint C4d: a marker for hepatic transplant rejection
    R Lorho
    Hopital de Pontchaillou, Service des Maladies du Foie, CHU Pontchaillou, 35033 Rennes Cedex, France
    Transplant Proc 38:2333-4. 2006
    ..The deposit of C4d provides evidence of activation of humoral immunity. To attempt to confirm this hypothesis, we searched for the presence of C4d in posttransplant hepatic biopsies...
  34. ncbi request reprint Squamous cell carcinoma arising in a hepatic forgut cyst
    Anne Sophie de Lajarte-Thirouard
    Department of Pathology, Hopital Pontchaillou, Rennes, France
    Pathol Res Pract 198:697-700. 2002
    ..Squamous carcinoma might develop in a context of inflammation as in biliary cyst. In agreement with the first case described in the literature, this report also suggests that a large-sized symptomatic hepatic cyst should be excised...
  35. ncbi request reprint Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function
    Lenaick Detivaud
    Institut National de la Sante et de la Recherche Medicale, Rennes, France
    Blood 106:746-8. 2005
    ..Moreover, we found in humans that hepcidin levels correlated with hepatic iron stores and hemoglobin levels and may also be affected by hepatic dysfunction...
  36. ncbi request reprint Auxiliary liver transplantation and bioartificial bridging procedures in treatment of acute liver failure
    Karim Boudjema
    Département de chirurgie viscérale, Hôpital Universitaire Pontchaillou, 1 rue Henri Le Guilloux, 35033 Rennes, France
    World J Surg 26:264-74. 2002
    ....
  37. ncbi request reprint Ex vivo right trisegmentectomy with reconstruction of inferior vena cava and "flop" reimplantation
    David Lechaux
    Départment de Chirurgie Viscérale, Centre Hospitalier Universitaire de Rennes, Hopital Pontchaillou, France
    J Am Coll Surg 194:842-5. 2002
  38. ncbi request reprint Successful treatment of intrahepatic biloma by combined percutaneous and endoscopic technique: an intrabiloma "rendezvous"
    Abdennaceur El Idrissi-Lamghari
    Department of Gastroenterology, Universitary Pontchaillou Hospital, 35033 Rennes, France
    Gastrointest Endosc 63:721-3. 2006
  39. ncbi request reprint Indication of liver transplantation in severe alcoholic liver cirrhosis: quantitative evaluation and optimal timing
    Bartholomeus Johannes Veldt
    Service des Maladies du Foie and INSERM U522, Centre Hospitalier Universitaire, Hopital Pontchaillou, 35033 Rennes, France
    J Hepatol 36:93-8. 2002
    ..The aim of our study was to evaluate the proportion of patients with severe alcoholic cirrhosis who would need orthotopic liver transplantation (OLT) and to determine the optimal delay to evaluate an abstinent patient for transplantation...
  40. doi request reprint Drug-metabolising enzymes are down-regulated by hypoxia in differentiated human hepatoma HepaRG cells: HIF-1alpha involvement in CYP3A4 repression
    Claire Legendre
    INSERM U522, Hopital Pontchaillou, Rennes F 35033, France
    Eur J Cancer 45:2882-92. 2009
    ..Thus, HepaRG cells might represent a new in vitro model to test anticancer agents in hypoxic versus normoxic conditions...
  41. doi request reprint [Combined liver-kidney transplantation: indications and results]
    K Ferhi
    Service d Urologie, CHU de Rennes, Rennes, France
    Prog Urol 18:245-50. 2008
    ..The purpose of this article is to report our experience concerning the indications and results for combined liver-kidney transplantation in our centre...
  42. ncbi request reprint [Technical aspects of combined heart, liver and kidney procurement]
    D Lechaux
    Département de chirurgie viscérale et de transplantation, Centre Hospitalier Universitaire de Rennes, Hopital Pontchaillou, 2, rue Henri Le Guilloux, 35033 Rennes Cedex 9, France
    Ann Chir 129:103-13. 2004
    ..The goal of multiple organ procurement is to retrieve intact organs fully. This goal can only be reached if the organ dissection and preservation are optimal...