P Bossi

Summary

Country: France

Publications

  1. ncbi request reprint [The plague, possible bioterrorist act]
    Philippe Bossi
    Service de maladies infectieuses et tropicales groupe hospitalier pitié salpêtrière 47 83, Boulevard de l Hopital, 75013 Paris France
    Presse Med 32:804-7. 2003
  2. ncbi request reprint Bichat guidelines for the clinical management of anthrax and bioterrorism-related anthrax
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E3-4. 2004
  3. ncbi request reprint Bichat guidelines for the clinical management of plague and bioterrorism-related plague
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E5-6. 2004
  4. ncbi request reprint [Tularemia, a potential bioterrorism weapon]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75651 Paris
    Presse Med 32:1126-30. 2003
  5. ncbi request reprint Bichat guidelines for the clinical management of haemorrhagic fever viruses and bioterrorism-related haemorrhagic fever viruses
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E11-2. 2004
  6. ncbi request reprint Bichat guidelines for the clinical management of botulism and bioterrorism-related botulism
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E13-4. 2004
  7. ncbi request reprint [Severe acute respiratory syndrome: update]
    P Bossi
    Service de Maladies Infectieuses et Tropicales, Hopital de la Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Rev Med Interne 24:672-80. 2003
  8. ncbi request reprint [Q fever, a potential biowarfare agent]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Hôpital Pitié Salpêtrière Paris 75
    Presse Med 32:1618-21. 2003
  9. ncbi request reprint Bichat guidelines for the clinical management of brucellosis and bioterrorism-related brucellosis
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E15-6. 2004
  10. ncbi request reprint Bichat guidelines for the clinical management of glanders and melioidosis and bioterrorism-related glanders and melioidosis
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E17-8. 2004

Detail Information

Publications74

  1. ncbi request reprint [The plague, possible bioterrorist act]
    Philippe Bossi
    Service de maladies infectieuses et tropicales groupe hospitalier pitié salpêtrière 47 83, Boulevard de l Hopital, 75013 Paris France
    Presse Med 32:804-7. 2003
    ..A dead cell vaccine exists, but its efficacy in terms of protection from primary pneumonia appears inadequate...
  2. ncbi request reprint Bichat guidelines for the clinical management of anthrax and bioterrorism-related anthrax
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E3-4. 2004
    ..Treatment consists of massive doses of antibiotics and supportive care. Isolation is not necessary. Antibiotics such as ciprofloxacin are recommended for post-exposure prophylaxis during 60 days...
  3. ncbi request reprint Bichat guidelines for the clinical management of plague and bioterrorism-related plague
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E5-6. 2004
    ..For the other clinical types of the disease, patients should be isolated for the first 48 hours after the initiation of treatment...
  4. ncbi request reprint [Tularemia, a potential bioterrorism weapon]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75651 Paris
    Presse Med 32:1126-30. 2003
    ..IN GENERAL PRACTICE: Tularemia is a disease that requires official notification. Many guidelines exist for the treatment and prophylaxis of patients having been exposed to F. tularensis...
  5. ncbi request reprint Bichat guidelines for the clinical management of haemorrhagic fever viruses and bioterrorism-related haemorrhagic fever viruses
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E11-2. 2004
    ..Ribavirin is recommended for the treatment and the prophylaxis of the arenaviruses and the bunyaviruses, but is not effective for the other families. All patients must be isolated and receive intensive supportive therapy...
  6. ncbi request reprint Bichat guidelines for the clinical management of botulism and bioterrorism-related botulism
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E13-4. 2004
    ..Trivalent equine antitoxins (A,B,E) must be given to patients as soon as possible after clinical diagnosis. Heptavalent human antitoxins (A-G) are available in certain countries...
  7. ncbi request reprint [Severe acute respiratory syndrome: update]
    P Bossi
    Service de Maladies Infectieuses et Tropicales, Hopital de la Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Rev Med Interne 24:672-80. 2003
    ..The severe acute respiratory syndrome (SARS) has recently been recognised as a new clinical entity and a new emerging infectious disease that is highly contagious with significant mortality...
  8. ncbi request reprint [Q fever, a potential biowarfare agent]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Hôpital Pitié Salpêtrière Paris 75
    Presse Med 32:1618-21. 2003
    ..In fact C. burnetii would more likely be used as a disabling weapon...
  9. ncbi request reprint Bichat guidelines for the clinical management of brucellosis and bioterrorism-related brucellosis
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E15-6. 2004
    ..The combination of ofloxacin plus rifampicin is associated with good results. Even if there is little evidence to support its utility for post-exposure prophylaxis, doxycycline plus rifampicin is recommended for 3 to 6 weeks...
  10. ncbi request reprint Bichat guidelines for the clinical management of glanders and melioidosis and bioterrorism-related glanders and melioidosis
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E17-8. 2004
    ..Post-exposure prophylaxis with trimethoprim-sulfamethoxazole is recommended in case of a biological attack. There is no vaccine available for humans...
  11. ncbi request reprint Bichat guidelines for the clinical management of smallpox and bioterrorism-related smallpox
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E7-8. 2004
    ..There is no established antiviral treatment for smallpox. The most effective prevention is vaccination before exposure...
  12. ncbi request reprint Bichat guidelines for the clinical management of Q fever and bioterrorism-related Q fever
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E19-20. 2004
    ..Nevertheless, treatment can shorten the duration of illness and decrease the risk of complications such as endocarditis. Post-exposure prophylaxis is recommended after the exposure in the case of a bioterrorist attack...
  13. ncbi request reprint [Diagnosis of sepsis, severe sepsis and septic shock]
    Philippe Bossi
    Service des Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, Paris 75
    Presse Med 33:262-4; discussion 269. 2004
    ..Genetic susceptibility probably intervenes, genetic variability playing either a protective or a deleterious role (the interest of Toll-like receptors)...
  14. ncbi request reprint Bichat guidelines for the clinical management of viral encephalitis and bioterrorism-related viral encephalitis
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E21-2. 2004
    ..There is no effective drug therapy for the treatment of these diseases and treatment is mainly supportive, but vaccines protecting against some of these viruses do exist...
  15. ncbi request reprint [Botulism toxin, bioterrorist weapon]
    Philippe Bossi
    Service de maladies infectieuses et tropicales Hôpital Pitié Salpêtrière 47 83 Boulevard de l Hôpital, 75013 Paris
    Presse Med 32:463-5. 2003
    ..The use of the botulinum toxin for terrorist aims in the form of aerosols is a perfectly credible eventuality. The botulinum toxin is the most potent toxin known; it is easy to produce and can lead to massive destruction...
  16. ncbi request reprint Bichat clinical guidelines for bioterrorist agents
    Philippe Bossi
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E1-2. 2004
  17. ncbi request reprint [Emerging or re-emerging infections that can be used for bioterrorism]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Presse Med 34:149-55. 2005
    ..INFECTIONS THAT REQUIRE RECOGNITION: The role of practitioners in the rapid recognition of bioterrorism-related infections is crucial. Hence, updated knowledge on these potentially emerging or reemerging infections is required...
  18. ncbi request reprint [Management of therapeutic failure in HIV-infected patients]
    P Bossi
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83, Bd de l Hopital, F 75651 Paris
    Presse Med 30:806-12. 2001
    ..The principal factors predictive of treatment failure are low CD4 counts and high viral load prior to institution of the antiretroviral treatment. Several virological and pharmacological mechanisms are implicated...
  19. ncbi request reprint Bioterrorism: management of major biological agents
    P Bossi
    Department of Infectious Diseases, Pitie Salpetriere Hospital, 47 83 Bd de l Hopital, 75013, Paris, France
    Cell Mol Life Sci 63:2196-212. 2006
    ..More than 180 pathogens have been reported to be potential agents for bioterrorism. The following is an overview of several agents that could be involved in a biological attack...
  20. ncbi request reprint [Risk of smallpox, vaccination, bioterrorism]
    P Bossi
    Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier, Pitie Salpetriere, 47 83, Bd de l Hopital, 75013 Paris, France
    Presse Med 34:177-184. 2005
    ....
  21. ncbi request reprint Severe acute disseminated toxoplasmosis acquired by an immunocompetent patient in French Guiana
    Philippe Bossi
    Department of Infectious Diseases, Pitie Salpetriere Hospital, Paris, France
    Scand J Infect Dis 34:311-4. 2002
    ..We report a case of severe acute disseminated toxoplasmosis acquired by an immunocompetent patient in French Guiana and review the literature...
  22. ncbi request reprint GENOPHAR: a randomized study of plasma drug measurements in association with genotypic resistance testing and expert advice to optimize therapy in patients failing antiretroviral therapy
    P Bossi
    Department of Infectious Diseases, Pitie Salpetriere Hospital, 47 83 boulevard de l Hopital, 75013 Paris, France
    HIV Med 5:352-9. 2004
    ..To evaluate the benefits of therapeutic drug monitoring (TDM) in association with genotypic resistance testing and expert advice to optimize therapy in multiexperienced patients infected with HIV-1...
  23. ncbi request reprint [Smallpox, bioterrorism agent]
    Philippe Bossi
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris
    Presse Med 31:1813-7. 2002
    ..A CONSIDERABLE RISK: Among the infectious agents that might be used as terrorist weapons, the smallpox virus represents a sufficiently high risk, which is difficult to manage and must be seriously taken into account...
  24. ncbi request reprint [Anthrax in the era of biowarfare]
    Philippe Bossi
    Service de maladies infectieuses et tropicales Groupe hospitalier Pitié Salpêtrière, Paris
    Presse Med 32:167-73. 2003
    ..The cutaneous and digestive forms are also possible...
  25. ncbi request reprint [Epidemiological features and incidence trends of primary cerebral lymphomas observed in 80 HIV-infected patients from 1983 to 1999]
    A Rigolet
    Services de Maladies Infectieuses et Tropicales, , 47-83, , 75651 Paris, France
    Pathol Biol (Paris) 49:572-5. 2001
    ..CONCLUSION: After the introduction of HAART (1996), the incidence of PCNSL has decreased drastically and survival was increased...
  26. ncbi request reprint [Glanders, melioidosis and biowarfare]
    Amélie Guilhot
    Service de maladies infectieuses et tropicales Hôpital Pitié Salpêtrière, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Presse Med 34:185-8. 2005
    ..We have to consider these agents as possible biological warfare agents. Europeans guidelines for treatment and post-exposure prophylaxis are detailed...
  27. ncbi request reprint [Lymph-node tuberculosis in patients infected or not with HIV: general characteristics, clinical presentation, microbiological diagnosis and treatment]
    P Hochedez
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Pathol Biol (Paris) 51:496-502. 2003
    ..Three HIV infected patients were infected by mycobacteria resistant to at least one antibiotic (isoniazid, 1; rifampicin, 1; isoniazid, streptomycin, etambutool, 1). All the patients recovered...
  28. ncbi request reprint P-glycoprotein in blood CD4 cells of HIV-1-infected patients treated with protease inhibitors
    P Bossi
    Department of Virology, Pitie Salpetriere Hospital, 47 83 Bd de l Hopital, Paris, France
    HIV Med 4:67-71. 2003
    ..P-gps have been detected on peripheral CD4 blood cells in HIV-1-infected, but antiretroviral-naive patients...
  29. pmc Genotypic inhibitory quotient as predictor of virological response to ritonavir-amprenavir in human immunodeficiency virus type 1 protease inhibitor-experienced patients
    Anne Genevieve Marcelin
    Department of Virology, INSERM EMI 0214, Bichat Claude Bernard Hospital, Paris, France
    Antimicrob Agents Chemother 47:594-600. 2003
    ....
  30. ncbi request reprint Bichat guidelines for the clinical management of tularaemia and bioterrorism-related tularaemia
    Philippe Bossi
    Taskforce on Bioterrorism BICHAT, Public Health Directorate, European Commission, Luxembourg
    Euro Surveill 9:E9-10. 2004
    ..Quinolone is an effective alternative drug. No isolation measures for patients with pneumonia are necessary. Streptomycin, gentamicin, doxycycline or ciprofloxacin are recommended for post-exposure prophylaxis...
  31. ncbi request reprint Selection of the same mutation in the U69 protein kinase gene of human herpesvirus-6 after prolonged exposure to ganciclovir in vitro and in vivo
    C Manichanh
    Laboratoire de Virologie, UPRES EA 2387, CERVI, , , 75651 Paris Cedex 13, France
    J Gen Virol 82:2767-76. 2001
    ..These findings provide strong circumstantial evidence that the M(318)V change of the PK gene is associated with resistance to GCV and raise the question of cross resistance to this drug among different betaherpesviruses...
  32. ncbi request reprint [Acute viral meningitis. Epidemiologic, clinical and biological characteristics of 29 hospitalized patients]
    D Sene
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83 Bd de l Hopital, F75651 Paris
    Presse Med 31:254-8. 2002
  33. ncbi request reprint [Vaccinal strategies against smallpox in France]
    F Bricaire
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Med Mal Infect 34:1-5. 2004
  34. pmc Toxoplasma gondii-associated Guillain-Barré syndrome in an immunocompetent patient
    P Bossi
    Departments of Infectious Diseases, Pitie Salpetriere Hospital, Paris, France
    J Clin Microbiol 36:3724-5. 1998
    ..The patient's condition improved with pyrimethamine and sulfadiazine. Only the standard treatment for toxoplasmosis was effective, whereas intravenous immunoglobulins were ineffective...
  35. ncbi request reprint [Bioterrorism and health security in the European Union]
    Georgios Gouvras
    Public Health Directorate, JMO C3 32, European Commission, L 2920 Luxembourg
    Presse Med 34:156-60. 2005
    ....
  36. ncbi request reprint [Current clinical aspects of HIV/AIDS]
    V Zeller
    Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitie Salpetriere, 47 83, Boulevard de l Hopital, F75013 Paris
    Presse Med 31:74-9. 2002
    ..At present, heterosexuality is the most frequent risk factor for HIV-infection (51%). Pneumocystis pneumonia remains the most common opportunistic illness in HIV-infected patients (28%)...
  37. ncbi request reprint Resistance profiles observed in virological failures after 24 weeks of amprenavir/ritonavir containing regimen in protease inhibitor experienced patients
    Anne Genevieve Marcelin
    Department of Virology, Pitie Salpetriere Hospital, Paris, France
    J Med Virol 74:16-20. 2004
    ..There was no relation between the resistance pathways selected with either APV or ritonavir plasma minimal concentration, but higher APV plasma minimal concentration were associated with a lower rate of resistance mutations selection...
  38. ncbi request reprint Foscarnet salvage therapy for patients with late-stage HIV disease and multiple drug resistance
    Ana Canestri
    Department des Maladies Infectieuses, Hopital Pitie Salpetriere, Paris, France
    Antivir Ther 11:561-6. 2006
    ..To evaluate the efficacy of foscarnet on HIV infection in patients with late-stage HIV disease and multiple drug resistance...
  39. ncbi request reprint Discontinuation of secondary prophylaxis against disseminated Mycobacterium avium complex infection and toxoplasmic encephalitis
    Valerie Zeller
    Service des Maladies Infectieuses et Tropicales, CHU Pitie Salpetriere, 75651 Paris Cedex 013, France
    Clin Infect Dis 34:662-7. 2002
    ....
  40. ncbi request reprint Fatal HHV-6 associated encephalitis in an HIV-1 infected patient treated with cidofovir
    Myrto Astriti
    Department of Infectious Diseases, Pitie Salpetriere Hospital, 47 83 boulevard de l Hopital, 75651 Paris Cedex 13, France
    J Infect 52:237-42. 2006
    ..We describe the case of a patient infected with HIV and a concomitant HHV-6 encephalitis. The patient experienced virological failure following cidofovir treatment. RT-PCR was used both for early diagnosis and follow-up...
  41. ncbi request reprint [Haemorrhagic fever viruses, possible bioterrorist use]
    Sophie Rigaudeau
    Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Presse Med 34:169-76. 2005
    ..Except for yellow fever, there is no vaccination for the other forms of viral haemorrhagic fever...
  42. ncbi request reprint [Viral encephalitis virus, a new bioterrorist menace]
    Sophie Rigaudeau
    Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitie Salpetriere, 47 83, Boulevard de l Hopital, 75013 Paris, France
    Presse Med 34:161-8. 2005
    ..The aim of terrorist groups who would use this type of weapon is more to provoke panic and disorganisation than to kill as many people as possible...
  43. ncbi request reprint Atypical toxoplasmic manifestation after discontinuation of maintenance therapy in a human immunodeficiency virus type 1-infected patient with immune recovery
    Jade Ghosn
    Departement des Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire Pitié Paris, France
    Clin Infect Dis 37:e112-4. 2003
    ..This atypical recurrence was more likely to be a reinfection than a reactivation, as attested by the genotypic analysis of the Toxoplasma gondii strain recovered from the patient...
  44. ncbi request reprint [Evaluation of residual immune response against human pox virus before and after revaccination in healthy volunteers]
    Francois Bricaire
    Service des Maladies Infectieuses et Tropicales, G H Pitié Salpêtrière, 47 83 boulevard de l Hopital, 75013 Paris
    Bull Acad Natl Med 190:1035-46; discussion 1046-9. 2006
    ..Three-quarters of the subjects had a proliferative response. This response was lower after the age of 55 years but could be reactivated by revaccination...
  45. pmc Demographic and clinical factors associated with response to smallpox vaccine in preimmunized volunteers
    Philippe Bossi
    Department of Infectious Diseases, University Pierre and Marie Curie, Paris VI, Paris, France
    PLoS ONE 3:e4087. 2008
    ..This program included the establishment of a preoutbreak national team that could be revaccinated against smallpox...
  46. ncbi request reprint Low T cell responses to human herpesvirus 8 in patients with AIDS-related and classic Kaposi sarcoma
    Amelie Guihot
    Laboratoire d Immunologie Cellulaire et Tissulaire du Pr Debre, INSERM UMR S 543, Batiment CERVI, Hopital Pitie Salpetriere, 47 bd de l Hopital, 75013, Paris, France
    J Infect Dis 194:1078-88. 2006
    ..We hypothesized that KS is linked to deficiencies in specific anti-HHV-8 T cell immunity...
  47. ncbi request reprint [Genital herpes: epidemiology, transmission, clinic, asymptomatic viral excretion, impact on other sexually transmitted diseases, prevention, and treatment]
    P Bossi
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83, Bd de l Hopital, 75651 Paris Cedex 13 Paris France
    Ann Dermatol Venereol 129:477-93. 2002
    ..Information and education of patients with genital herpes are key elements for prevention. Use of preservatives appears to be effective. New vaccine strategies favoring humoral and cellular response should be studied...
  48. ncbi request reprint Medication misuse in hospitalized patients with renal impairment
    L Salomon
    University Hospital Pitié Salpêtrière AP HP, Paris VI, Public Health Department, Paris, France
    Int J Qual Health Care 15:331-5. 2003
    ..The purpose of this study was to determine the frequency and potential consequences of a lack of dosage adjustment in hospitalized patients with renal impairment...
  49. ncbi request reprint [Management before suspicion of sporadic cases of avian influenza]
    P Bossi
    Département de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, 47 83 boulevard de l Hopital, Paris Cedex 13, France
    Rev Mal Respir 25:497-9. 2008
  50. pmc Cryptococcal neuroradiological lesions correlate with severity during cryptococcal meningoencephalitis in HIV-positive patients in the HAART era
    Caroline Charlier
    Centre National de Référence Mycologie et Antifongiques, Unité de Mycologie Moléculaire, CNRS URA 3012, Institut Pasteur, Paris, France
    PLoS ONE 3:e1950. 2008
    ..Given this, we suggest that investigation for cryptococcosis-related lesions is merited, even in the absence of neurological abnormality, if a high fungal burden is suspected on the basis of high serum and/or CSF antigen titers...
  51. ncbi request reprint Acute bacterial meningitis in a patient receiving ibuprofen
    Jerome Tamburini
    Department of Infectious Diseases, Pitie Salpetriere Hospital, 47 83 boulevard de l Hopital, 75651 Paris, Cedex 13 France
    J Infect 51:336-7. 2005
    ..Anti-inflammatory therapy such as NSAIDs could reduce CSF inflammation and modify the clinical outcome in patients with bacterial meningitis. However, the use of NSAIDs is not recommended in bacterial meningitis due to a lack of studies...
  52. pmc Control of vaccinia virus skin lesions by long-term-maintained IFN-gamma+TNF-alpha+ effector/memory CD4+ lymphocytes in humans
    Bénédicte Puissant-Lubrano
    INSERM U945, Paris, France
    J Clin Invest 120:1636-44. 2010
    ....
  53. ncbi request reprint Cytokine pattern in Kaposi's sarcoma associated with immune restoration disease in HIV and tuberculosis co-infected patients
    Jerome Tamburini
    Department of Infectious Diseases, Pitie Salpetriere Hospital, Paris, France
    AIDS 21:1980-3. 2007
    ..Analysis of VEGF and pro-inflammatory cytokines led us to hypothesize that Kaposi's sarcoma could be promoted by the tuberculosis immune response...
  54. pmc The European Commission's Task Force on Bioterrorism
    Anders Tegnell
    Task Force on Biological and Chemical Agent Threats, Public Health Directorate, European Commission, L 2920 Luxembourg, Belgium
    Emerg Infect Dis 9:1330-2. 2003
  55. ncbi request reprint [Severe acute respiratory syndrome: a singular epidemic of viral pneumonia]
    Amelie Guihot
    Service de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, Paris
    Presse Med 33:344-51. 2004
    ..There is no specific treatment. Ribavirin associated with steroids have been used with success in numerous cases...
  56. ncbi request reprint [Rickettsioses]
    Jade Ghosn
    Service des Maladies Infectieuses et Tropicales, groupe hospitalier La Pitié La Salpêtrière, 75651 Paris Cedex 13
    Rev Prat 55:707-12. 2005
    ..Travellers to endemic areas should be encouraged to use personal protective measures...
  57. ncbi request reprint Lung cancer in patients with HIV Infection and review of the literature
    Jean Philippe Spano
    Pitie Salpetriere Hospital, Department of Medical Oncology, bld de I Hopital, 75013 Paris, France
    Med Oncol 21:109-15. 2004
    ..The improved survival of patients since the use of highly active antiretroviral treatments has lead to the reporting of non-AIDS defining tumors, such as lung cancer...
  58. pmc Chikungunya infection in travelers
    Patrick Hochedez
    Hopital Pitie Salpetriere, Paris, France
    Emerg Infect Dis 12:1565-7. 2006
    ..We describe the manifestations of chikungunya virus infection in travelers returning from these islands, with focus on skin manifestations...
  59. doi request reprint [Herpes simplex virus meningitis in 11 patients]
    Charles Binetruy
    Département de Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, Paris, France
    Med Mal Infect 38:141-5. 2008
    ..We reviewed retrospectively the demographic, clinical, biological characteristics and outcomes of 11 patients with HSV meningitis...
  60. ncbi request reprint Severe acute disseminated toxoplasmosis
    Philippe Bossi
    Lancet 364:579. 2004
  61. ncbi request reprint [Antiretroviral-induced toxiderma in HIV-infected patients]
    Eric Caumes
    Service des Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, Paris 75
    Presse Med 32:1325-33. 2003
    ..The practical approach varies depending on the drug responsible, the clinical form of the toxiderma and the possible alternatives...
  62. ncbi request reprint [Emerging viral diseases]
    Francois Bricaire
    Service des Maladies infectieuses et tropicales Groupe Hospitalier de la Pitié Salpêtrière, 47 Bld de l Hopital, 75015 Paris
    Bull Acad Natl Med 190:597-608; discussion 609, 625-7. 2006
    ..Pox and Monkeypox are "virtually emerging" viruses that have potential for use in bioterrorism. The management and treatment of these emerging infectious diseases calls for new approaches, organizations and infrastructures...
  63. ncbi request reprint HHV-6 variant A meningoencephalitis after allogeneic hematopoietic stem cell transplantation diagnosed by quantitative real-time polymerase chain reaction
    Adrienne de Labarthe
    Transplantation 80:539. 2005
  64. ncbi request reprint [Treatment of severe sepsis and septic shock]
    David Grimaldi
    Service des Maladies Infectieuses et Tropicales, Hopital Pitie Salpetriere, Paris 75
    Presse Med 33:265-8; discussion 269. 2004
    ..Intensive insulin therapy is aimed at maintaining normal glycemia in the patients for as long as possible...
  65. ncbi request reprint Discontinuation of maintenance therapy for cryptococcal meningitis in patients with AIDS treated with highly active antiretroviral therapy: an international observational study
    Cristina Mussini
    Clinic of Infectious and Tropical Diseases, University of Modena and Reggio Emilia, Azienda Policlinico, Modena, Italy
    Clin Infect Dis 38:565-71. 2004
    ..Recurrent cryptococcal infection should be suspected in patients whose serum cryptococcal antigen test results revert back to positive after discontinuation of maintenance therapy...
  66. ncbi request reprint Stevens-Johnson syndrome associated with abacavir therapy
    Philippe Bossi
    Clin Infect Dis 35:902. 2002
  67. ncbi request reprint [HAART and changes of epidemiology, treatment and prognosis of HIV-positive patients with Kaposi's sarcoma and lymphoma]
    Jean Gabarre
    Services d hématologie clinique et des maladies infectieuses et tropicales, Hopital Pitie Salpetriere, 47, Boulevard de l Hopital, 75013 Paris
    Bull Cancer 90:419-25. 2003
    ..The administration of chemotherapy with HAART does not seem to increase toxicity...
  68. ncbi request reprint [Infectious agents as terrorism weapons]
    Philippe Bossi
    Presse Med 34:147-8. 2005
  69. ncbi request reprint High indinavir plasma concentrations in HIV-positive patients co-infected with hepatitis B or C virus treated with low doses of indinavir and ritonavir (400/100 mg twice a day) plus two nucleoside reverse transcriptase inhibitors
    Philippe Bossi
    AIDS 17:1108-10. 2003
  70. ncbi request reprint [Bioterrorism with brucellosis]
    Amelie Guihot
    Service de maladies infectieuses et tropicales Hôpital Pitié Salpêtrière, Paris 75
    Presse Med 33:119-22. 2004
    ..However, the morbidity of this agent should not be underrated since it leads to chronic and disabling pathologies...
  71. ncbi request reprint Thoracic radiographic and CT findings of multicentric Castleman disease in HIV-infected patients
    Amelie Guihot
    Service de Pneumologie, Hopital Foch, Suresnes, France
    J Thorac Imaging 22:207-11. 2007
    ..In this pictorial essay, we describe different thoracic imaging of MCD, with particular emphasis on computed tomography findings, in 13 HIV-infected patients with histologically proved MCD...
  72. ncbi request reprint Upper urinary tract infection as a leading cause of fever among female travelers returning from the tropics
    Valerie Zeller
    Department of Infectious and Tropical Diseases, Hopital Pitie Salpetriere, 47 83 boulevard de l Hopital, 75651 Paris Cedex 013, France
    J Travel Med 10:139-40. 2003
  73. ncbi request reprint [Physiopathology of severe sepsis]
    Vincent Caille
    Service de Reanimation Polyvalente, Hopital Ambroise Pare, Boulogne Billancourt 92
    Presse Med 33:256-61; discussion 269. 2004
    ....
  74. ncbi request reprint Pneumonia among travelers returning from abroad
    Séverine Ansart
    Service des Maladies Infectieuses et Tropicales, Groupe Hospitalier Pitie Salpetriere, Paris, France
    J Travel Med 11:87-91. 2004
    ....