Christophe Bosc

Summary

Country: France

Publications

  1. ncbi Identification of novel bifunctional calmodulin-binding and microtubule-stabilizing motifs in STOP proteins
    C Bosc
    Commissariat à l Energie Atomique Laboratoire du Cytosquelette, INSERM Unité 366, Département de Biologie Moléculaire et Structurale Cytosquelette, Commissariat a l Energie Atomique Grenoble, F 38054 Grenoble Cedex 9, France
    J Biol Chem 276:30904-13. 2001
  2. ncbi STOP proteins
    Christophe Bosc
    Laboratoire du Cytosquelette, INSERM U366, DRDC CS, CEA Grenoble, 17 rue des Martyrs, F 38054 Grenoble Cedex 9, France
    Biochemistry 42:12125-32. 2003
  3. ncbi STOP-like protein 21 is a novel member of the STOP family, revealing a Golgi localization of STOP proteins
    Sylvie Gory-Fauré
    INSERM U366, Département Recherche et Dynamique Cellulaire Cytosquelette, Commissariat a l Energie Atomique Grenoble, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France
    J Biol Chem 281:28387-96. 2006
  4. ncbi Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II
    Julie Baratier
    Laboratoire du Cytosquelette, INSERM U366, DRDC CS, CEA Grenoble, 17 rue des Martyrs, 38054 Grenoble Cedex 9, France
    J Biol Chem 281:19561-9. 2006
  5. pmc The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders
    Annie Andrieux
    Laboratoire du Cytosquelette, INSERM U366, Département Réponse et Dynamique Cellulaire, CEA Grenoble, 38054 Grenoble, France
    Genes Dev 16:2350-64. 2002
  6. pmc Two related subpellicular cytoskeleton-associated proteins in Trypanosoma brucei stabilize microtubules
    Cécile Vedrenne
    Laboratoire de Parasitologie Moleculaire, université Victor Segalen de Bordeaux II, Unité Mixte Recherche 5016 Centre National de la Recherche Scientifique, 33076 Bordeaux, France
    Mol Biol Cell 13:1058-70. 2002
  7. ncbi Interaction of STOP with neuronal tubulin is independent of polyglutamylation
    Crystel Bonnet
    Laboratoire de Biochimie Cellulaire CNRS UMR 7098, Universite Pierre et Marie Curie, 9 quai Saint Bernard, 75252 Paris Cedex 05, France
    Biochem Biophys Res Commun 297:787-93. 2002
  8. pmc A vital role of tubulin-tyrosine-ligase for neuronal organization
    Christian Erck
    Department of Cell Biology, German Research Center for Biotechnology, D 38124 Braunschweig, Germany
    Proc Natl Acad Sci U S A 102:7853-8. 2005

Collaborators

Detail Information

Publications8

  1. ncbi Identification of novel bifunctional calmodulin-binding and microtubule-stabilizing motifs in STOP proteins
    C Bosc
    Commissariat à l Energie Atomique Laboratoire du Cytosquelette, INSERM Unité 366, Département de Biologie Moléculaire et Structurale Cytosquelette, Commissariat a l Energie Atomique Grenoble, F 38054 Grenoble Cedex 9, France
    J Biol Chem 276:30904-13. 2001
    ..STOP modules represent novel bifunctional calmodulin-binding and microtubule-stabilizing sequences that may be essential for the generation of the different patterns of microtubule stabilization observed in cells...
  2. ncbi STOP proteins
    Christophe Bosc
    Laboratoire du Cytosquelette, INSERM U366, DRDC CS, CEA Grenoble, 17 rue des Martyrs, F 38054 Grenoble Cedex 9, France
    Biochemistry 42:12125-32. 2003
    ..Additionally, STOP-deficient mice may yield a pertinent model for the study of neuroleptics in illnesses such as schizophrenia, currently thought to result from defects in synapse function...
  3. ncbi STOP-like protein 21 is a novel member of the STOP family, revealing a Golgi localization of STOP proteins
    Sylvie Gory-Fauré
    INSERM U366, Département Recherche et Dynamique Cellulaire Cytosquelette, Commissariat a l Energie Atomique Grenoble, 17 rue des Martyrs, 38054 Grenoble, Cedex 9, France
    J Biol Chem 281:28387-96. 2006
    ..Thus neuronal proteins of the STOP family have the capacity to associate with Golgi material, which could be important for STOP synaptic functions...
  4. ncbi Phosphorylation of microtubule-associated protein STOP by calmodulin kinase II
    Julie Baratier
    Laboratoire du Cytosquelette, INSERM U366, DRDC CS, CEA Grenoble, 17 rue des Martyrs, 38054 Grenoble Cedex 9, France
    J Biol Chem 281:19561-9. 2006
    ..Thus, STOP phosphorylation by CaMKII may promote STOP translocation from microtubules to synaptic compartments where it may interact with actin, which could be important for STOP function in synaptic plasticity...
  5. pmc The suppression of brain cold-stable microtubules in mice induces synaptic defects associated with neuroleptic-sensitive behavioral disorders
    Annie Andrieux
    Laboratoire du Cytosquelette, INSERM U366, Département Réponse et Dynamique Cellulaire, CEA Grenoble, 38054 Grenoble, France
    Genes Dev 16:2350-64. 2002
    ..Additionally, STOP-/- mice may yield a pertinent model for study of neuroleptics in illnesses such as schizophrenia, currently thought to result from synaptic defects...
  6. pmc Two related subpellicular cytoskeleton-associated proteins in Trypanosoma brucei stabilize microtubules
    Cécile Vedrenne
    Laboratoire de Parasitologie Moleculaire, université Victor Segalen de Bordeaux II, Unité Mixte Recherche 5016 Centre National de la Recherche Scientifique, 33076 Bordeaux, France
    Mol Biol Cell 13:1058-70. 2002
    ..When overexpressed in T. brucei, both CAP15 and CAP17 cover the whole subpellicular corset and induce morphological disorders, cell cycle-based abnormalities, and subsequent asymmetric cytokinesis...
  7. ncbi Interaction of STOP with neuronal tubulin is independent of polyglutamylation
    Crystel Bonnet
    Laboratoire de Biochimie Cellulaire CNRS UMR 7098, Universite Pierre et Marie Curie, 9 quai Saint Bernard, 75252 Paris Cedex 05, France
    Biochem Biophys Res Commun 297:787-93. 2002
    ..And contrary to the other microtubule-associated proteins tested so far, STOP can bind quantitatively to any tubulin isoform whatever its degree of polyglutamylation...
  8. pmc A vital role of tubulin-tyrosine-ligase for neuronal organization
    Christian Erck
    Department of Cell Biology, German Research Center for Biotechnology, D 38124 Braunschweig, Germany
    Proc Natl Acad Sci U S A 102:7853-8. 2005
    ..Our results demonstrate a vital role of TTL for neuronal organization and suggest a requirement of Tyr-tubulin for proper control of neurite extensions...