Bruno Borghese

Summary

Country: France

Publications

  1. doi Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression
    Bruno Borghese
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Service de Gynécologie Obstétrique II, CHU Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod 23:1207-13. 2008
  2. doi Ovarian endometrioma: severe pelvic pain is associated with deeply infiltrating endometriosis
    Charles Chapron
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine Professor Chapron, Paris, France
    Hum Reprod 27:702-11. 2012
  3. doi [Intestinal endometriosis]
    Mahaut Leconte
    AP HP, Hopital Cochin, Universite Paris Descartes, Service de Chirurgie Digestive, hépatobiliaire et endocrinienne, 75679 Paris Cedex 14, France
    Presse Med 41:358-66. 2012
  4. doi An update on the pharmacological management of endometriosis
    Isabelle Streuli
    Service de Gynecologie, obstétrique et médecine de la reproduction, Groupe hospitalier du centre Cochin Broca Hôtel Dieu, CHU Cochin, Paris, France
    Expert Opin Pharmacother 14:291-305. 2013
  5. doi Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis
    Bruno Borghese
    Department of Gynecology and Obstetrics 2, Cochin University Hospital, Paris Descartes University, Public Hospitals of Paris AP HP, Paris, France
    Am J Pathol 180:1781-6. 2012
  6. pmc Increased serum oxidative stress markers in women with uterine leiomyoma
    Pietro Santulli
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Hopital Cochin, Department of GynecologyObstetrics II and Reproductive Medicine, 75679 Paris, France
    PLoS ONE 8:e72069. 2013
  7. doi Deep infiltrating endometriosis is associated with markedly lower body mass index: a 476 case-control study
    Marie Christine Lafay Pillet
    Service de Gynécologie Obstétrique II, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris AP HP, Groupe Hospitalier Universitaire GHU Ouest, Centre Hospitalier Universitaire CHU Cochin Saint Vincent de Paul, France
    Hum Reprod 27:265-72. 2012
  8. doi Sphingosine pathway deregulation in endometriotic tissues
    Pietro Santulli
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine, Paris, France
    Fertil Steril 97:904-11. 2012
  9. doi Questioning patients about their adolescent history can identify markers associated with deep infiltrating endometriosis
    Charles Chapron
    Faculte de Medecine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier, Paris, France
    Fertil Steril 95:877-81. 2011
  10. doi Incidence and risk factors of bladder injuries during laparoscopic hysterectomy indicated for benign uterine pathologies: a 14.5 years experience in a continuous series of 1501 procedures
    Marie Christine Lafay Pillet
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Hum Reprod 24:842-9. 2009

Collaborators

Detail Information

Publications31

  1. doi Genetic polymorphisms of matrix metalloproteinase 12 and 13 genes are implicated in endometriosis progression
    Bruno Borghese
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Service de Gynécologie Obstétrique II, CHU Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod 23:1207-13. 2008
    ..Matrix metalloproteinases (MMPs) may contribute to endometriosis. We tested whether eight functional polymorphisms of these genes could modify the risk of endometriosis...
  2. doi Ovarian endometrioma: severe pelvic pain is associated with deeply infiltrating endometriosis
    Charles Chapron
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine Professor Chapron, Paris, France
    Hum Reprod 27:702-11. 2012
    ..The objective of this study was to evaluate the significance of severe preoperative pain for patients presenting with ovarian endometrioma (OMA)...
  3. doi [Intestinal endometriosis]
    Mahaut Leconte
    AP HP, Hopital Cochin, Universite Paris Descartes, Service de Chirurgie Digestive, hépatobiliaire et endocrinienne, 75679 Paris Cedex 14, France
    Presse Med 41:358-66. 2012
    ..There is currently no cure other than surgical removal of lesions. Medical treatments are based on a hormone used to block ovarian function...
  4. doi An update on the pharmacological management of endometriosis
    Isabelle Streuli
    Service de Gynecologie, obstétrique et médecine de la reproduction, Groupe hospitalier du centre Cochin Broca Hôtel Dieu, CHU Cochin, Paris, France
    Expert Opin Pharmacother 14:291-305. 2013
    ..The most commonly used medications are non-steroidal anti-inflammatory drugs, GnRH agonists, androgen derivatives such as danazol, combined oral contraceptive pills, progestogens and more recently the levonorgestrel intrauterine system...
  5. doi Genetic polymorphisms of DNMT3L involved in hypermethylation of chromosomal ends are associated with greater risk of developing ovarian endometriosis
    Bruno Borghese
    Department of Gynecology and Obstetrics 2, Cochin University Hospital, Paris Descartes University, Public Hospitals of Paris AP HP, Paris, France
    Am J Pathol 180:1781-6. 2012
    ..Our study constitutes a first milestone toward a plausible role of DNMT3L in the establishment of specific DNA methylation patterns in endometrioma...
  6. pmc Increased serum oxidative stress markers in women with uterine leiomyoma
    Pietro Santulli
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Hopital Cochin, Department of GynecologyObstetrics II and Reproductive Medicine, 75679 Paris, France
    PLoS ONE 8:e72069. 2013
    ..We have analysed oxidative stress markers (thiols, advanced oxidized protein products (AOPP), protein carbonyls and nitrates/nitrites) in preoperative sera from women with histologically proven uterine leiomyoma...
  7. doi Deep infiltrating endometriosis is associated with markedly lower body mass index: a 476 case-control study
    Marie Christine Lafay Pillet
    Service de Gynécologie Obstétrique II, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris AP HP, Groupe Hospitalier Universitaire GHU Ouest, Centre Hospitalier Universitaire CHU Cochin Saint Vincent de Paul, France
    Hum Reprod 27:265-72. 2012
    ..We decided to evaluate the association between BMI and the different types of endometriosis, classified as superficial endometriosis (SUP), deep infiltrating endometriosis (DIE) and ovarian endometrioma (OMA)...
  8. doi Sphingosine pathway deregulation in endometriotic tissues
    Pietro Santulli
    Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Department of Gynecology Obstetrics II and Reproductive Medicine, Paris, France
    Fertil Steril 97:904-11. 2012
    ..To investigate key genes expression of the sphingosine-1-phosphate pathway in endometriotic tissues...
  9. doi Questioning patients about their adolescent history can identify markers associated with deep infiltrating endometriosis
    Charles Chapron
    Faculte de Medecine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier, Paris, France
    Fertil Steril 95:877-81. 2011
    ..To investigate whether the clinical history, particularly of the adolescence period, contains markers of deeply infiltrating endometriosis (DIE)...
  10. doi Incidence and risk factors of bladder injuries during laparoscopic hysterectomy indicated for benign uterine pathologies: a 14.5 years experience in a continuous series of 1501 procedures
    Marie Christine Lafay Pillet
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Hum Reprod 24:842-9. 2009
    ..The aim of this study was to evaluate the rate, the risk factors for bladder injuries in a series of 1501 laparoscopic hysterectomies indicated for benign uterine pathologies...
  11. doi Oral contraceptives and endometriosis: the past use of oral contraceptives for treating severe primary dysmenorrhea is associated with endometriosis, especially deep infiltrating endometriosis
    Charles Chapron
    Service de Gynécologie Obstétrique II and Reproductive Medicine, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Paris, France
    Hum Reprod 26:2028-35. 2011
    ..We therefore compared various characteristics of OC use and the surgical diagnosis of endometriosis histologically graded as superficial peritoneal endometriosis (SUP), ovarian endometrioma (OMA) or deep infiltrating endometriosis (DIE)...
  12. doi Absence of association between a functional polymorphism of ALOX15 gene and infertility in endometriosis
    Bruno Borghese
    Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, CHU Cochin Saint Vincent de Paul, Paris, France
    Fertil Steril 91:1414-6. 2009
    ..In our study population, ALOX15 -292 C/T was not correlated either with the risk of developing an endometriosis or with the risk of infertility...
  13. doi Profibrotic interleukin-33 is correlated with uterine leiomyoma tumour burden
    Pietro Santulli
    Department of Gynecology Obstetrics II and Reproductive Medicine, Sorbonne Paris Cité, Faculte de Medecine, Universite Paris Descartes, AP HP, Hopital Cochin, 75679 Paris, France
    Hum Reprod 28:2126-33. 2013
    ..Are interleukin-33 (IL-33) serum levels higher in women with uterine leiomyoma compared with controls without leiomyoma?..
  14. doi Serum and peritoneal interleukin-33 levels are elevated in deeply infiltrating endometriosis
    Pietro Santulli
    Department of Gynecology Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Sorbonne Paris Cité, Faculte de Medecine, AP HP, Hopital Cochin, 75679 Paris, France
    Hum Reprod 27:2001-9. 2012
    ..Interleukin 33 (IL-33) is a cytokine involved in fibrotic disorders. We have analyzed IL-33 levels in the sera and peritoneal fluids of women with various forms of endometriosis and investigated the correlation with disease activity...
  15. doi Severe ureteral endometriosis: the intrinsic type is not so rare after complete surgical exeresis of deep endometriotic lesions
    Charles Chapron
    Department of Obstetrics and Gynecology II and Reproductive Medicine, Universite Paris Descartes, Assistance Publique, Hopitaux de Paris AP HP, Groupe Hospitalier Universitaire GHU Ouest, Centre Hospitalier Universitaire CHU Cochin Saint Vincent de Paul, Paris, France
    Fertil Steril 93:2115-20. 2010
    ..To evaluate the rate of intrinsic ureteral endometriosis in patients presenting with severe ureteral endometriosis...
  16. doi Complete surgery for low rectal endometriosis: long-term results of a 100-case prospective study
    Bertrand Dousset
    Department of Digestive and Endocrine Surgery, University Hospital Cochin, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Ann Surg 251:887-95. 2010
    ....
  17. ncbi Relation between severity of dysmenorrhea and endometrioma
    Nicolas Chopin
    Universite Rene Descartes, Paris V, Paris, France
    Acta Obstet Gynecol Scand 85:1375-80. 2006
    ..To evaluate the relationship between the severity of dysmenorrhea and endometrioma...
  18. doi Surgery for bladder endometriosis: long-term results and concomitant management of associated posterior deep lesions
    Charles Chapron
    Department of Gynecology, Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, Centre Hospitalier Universitaire Cochin, Saint Vincent de Paul, Pavillon Lelong, 82 avenue Denfert Rochereau, 75014 Paris, France
    Hum Reprod 25:884-9. 2010
    ..The objectives of this study are to evaluate the rate of recurrence after partial cystectomy for patients presenting with bladder DIE and to outline the surgical modalities for handling associated posterior DIE nodules...
  19. ncbi Deeply infiltrating endometriosis: pathogenetic implications of the anatomical distribution
    Charles Chapron
    Service de Gynécologie Obstérique II, Unité de chirurgie gynécologique, Institut Cochin, IFR, Universite Paris V, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, France
    Hum Reprod 21:1839-45. 2006
    ..To investigate whether knowledge of the anatomical distribution of histologically proven deeply infiltrating endometriosis (DIE) lesions contributes to understanding the pathogenesis...
  20. doi Smoking habits of 411 women with histologically proven endometriosis and 567 unaffected women
    Charles Chapron
    Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Centre Hospitalier Universitaire Cochin Saint Vincent de Paul, Groupe Hospitalier Universitaire Ouest, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Fertil Steril 94:2353-5. 2010
    ....
  21. ncbi Measurement of hs-CRP is irrelevant to diagnose and stage endometriosis: prospective study of 834 patients
    Thibault Thubert
    Faculty of Medicine Université Paris Descartes, Sorbonne Paris Cité, Paris, France Department of Gynecology, Obstetrics, and Reproductive Medicine, Centre Hospitalier Universitaire Cochin of the Groupe Hospitalier Universitaire Ouest, Assistance Publique Hopitaux de Paris, Paris, France Electronic address
    Am J Obstet Gynecol 210:533.e1-533.e10. 2014
    ..Here, we assessed if the levels of high-sensitivity C-reactive protein (hs-CRP) in serum could constitute an effective method for detecting systemic inflammation during endometriosis...
  22. ncbi Preoperative work-up for patients with deeply infiltrating endometriosis: transvaginal ultrasonography must definitely be the first-line imaging examination
    Mathilde Piketty
    Department of Gynecology, Obstetrics II and Reproductive Medicine, Universite Paris Descartes, Paris, France
    Hum Reprod 24:602-7. 2009
    ..We compared the accuracy of TVUS and TRUS for diagnosing rectal wall involvement in patients presenting with histologically proved deeply infiltrating endometriosis (DIE)...
  23. ncbi Operative management of deeply infiltrating endometriosis: results on pelvic pain symptoms according to a surgical classification
    Nicolas Chopin
    Assistance Publique, Hopitaux de Paris, Service de Gynécologie Obstétrique II, Unité de chirurgie gynécologique, CHU Cochin Port Royal, Paris, France
    J Minim Invasive Gynecol 12:106-12. 2005
    ..To assess the results of complete surgical excision for patients with painful functional symptoms in a context of histologically proven deeply infiltrating endometriosis (DIE)...
  24. doi Markers of adult endometriosis detectable in adolescence
    Charles Chapron
    Université Paris Descartes Assistance Publique Hôpitaux de Paris, CHU Cochin, Department of OB GYN and Reproductive Medicine, Paris, France
    J Pediatr Adolesc Gynecol 24:S7-12. 2011
    ..Experimental verification of this insight, however, is needed before the concept that early diagnosis means lesser destructive surgery can be ascertained...
  25. doi Endometriosis and infertility: pathophysiology and management
    Dominique DE Ziegler
    Universite Paris Descartes, Centre Hospitalier Universitaire Cochin, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Lancet 376:730-8. 2010
    ..Weighing up the relative advantages of surgery, medical treatment and ART are the foundations for a global approach to infertility associated with endometriosis...
  26. ncbi Associated ovarian endometrioma is a marker for greater severity of deeply infiltrating endometriosis
    Charles Chapron
    Université Paris Descartes V, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Groupe Hospitalier Universitaire Ouest, CHU Cochin, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Paris, France
    Fertil Steril 92:453-7. 2009
    ..To investigate whether an associated ovarian endometrioma is a marker for severity of deep infiltrating endometriosis (DIE)...
  27. ncbi Ureteral complications from laparoscopic hysterectomy indicated for benign uterine pathologies: a 13-year experience in a continuous series of 1300 patients
    Franck Leonard
    Faculte de Medecine, Service de Gynécologie Obstétrique II et Médecine de la Reproduction, Unité de chirurgie gynécologique, Groupe Hospitalier Universitaire GHU Ouest, Paris, France
    Hum Reprod 22:2006-11. 2007
    ..The aim of this study was to evaluate the risk of ureteral injuries and to discuss how to avoid their occurence after laparoscopic hysterectomy indicated for benign uterine pathologies...
  28. doi Research resource: genome-wide profiling of methylated promoters in endometriosis reveals a subtelomeric location of hypermethylation
    Bruno Borghese
    département génétique et développement, Institut Cochin, 24 rue du Faubourg Saint Jacques, 75014 Paris, France
    Mol Endocrinol 24:1872-85. 2010
    ..We postulated that this original observation might participate to the chromosomal stability and protect the endometriotic lesion against malignancy...
  29. doi Gene expression profile for ectopic versus eutopic endometrium provides new insights into endometriosis oncogenic potential
    Bruno Borghese
    Institut Cochin, Universite Paris Descartes, Centre National de la Recherche Scientifique Unite Mixte de Recherche 8104, Paris, France
    Mol Endocrinol 22:2557-62. 2008
    ..The study constitutes a noteworthy update of gene profiling in endometriosis, by delivering the most complete and reliable list of dysregulated genes to date...
  30. ncbi Surgical management of deeply infiltrating endometriosis: an update
    Charles Chapron
    Service de Chirurgie Gynecologique, Unité de Chirurgie, Clinique Universitaire Baudelocque, 123, boulevard Port Royal, CHU Cochin Saint Vincent de Paul, 75014 Paris, France
    Ann N Y Acad Sci 1034:326-37. 2004
    ..Further studies are needed to specify the place and modalities of medical treatments preoperatively and postoperatively...
  31. ncbi Deeply infiltrating endometriosis originates from the retrocervical area
    Charles Chapron
    J Am Assoc Gynecol Laparosc 11:440; author reply 440-1. 2004