Research Topics
| G Y BoivinSummaryCountry: France Publications
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Detail Information
Publications
Alendronate increases bone strength by increasing the mean degree of mineralization of bone tissue in osteoporotic womenG Y Boivin
Inserm Unite 403, Faculté de Médecine R Laennec, Lyon, France
Bone 27:687-94. 2000..That these effects contribute to improved bone strength is demonstrated by the reduction in fracture incidence previously demonstrated in these patients...- Changes in bone remodeling rate influence the degree of mineralization of boneG Boivin
Inserm Unite 403, Faculté de Médecine R Laennec, Hopital Edouard Herriot, Lyon, France
Connect Tissue Res 43:535-7. 2002..In contrast, an activation of bone remodeling as in primary hyperparathyroidism lowered the mean DMB... - The mineralization of bone tissue: a forgotten dimension in osteoporosis researchG Boivin
Laboratoire d Histodynamique Osseuse, Faculté de Médecine R Laennec, 69372, Lyon Cedex 08, France
Osteoporos Int 14:S19-24. 2003..This emphasizes the value, as antiosteoporotic treatment, of SR, which is safe at the bone mineral level... - Contribution of raloxifene and calcium and vitamin D3 supplementation to the increase of the degree of mineralization of bone in postmenopausal womenG Boivin
Institut National de la Santé et de la Recherche Médicale Unité 403, Faculté de Médecine R Laennec, 69372 Lyon Cedex 08, France
J Clin Endocrinol Metab 88:4199-205. 2003..The profile of MDMB observed in biopsies after treatment with placebo and raloxifene, compared with baseline, closely resembles physiological premenopausal bone... - [Bone mineralization and mineral status]Georges Boivin
Inserm Unite 403, Faculté de Médecine R Laennec, Lyon, France
Therapie 58:409-13. 2003..More generally, these data indicate that the mineral status of bone tissue should be systematically taken into account during histomorphometric studies of bone... 
Mechanisms of the anabolic effects of teriparatide on bone: insight from the treatment of a patient with pycnodysostosisPascale Chavassieux
INSERM Research Unit 831 and Université de Lyon, Lyon, France
J Bone Miner Res 23:1076-83. 2008..Our data strongly suggest that some features of the osteoclastic phenotype--that are absent in pycnodysostosis--are a prerequisite for the anabolic effect of PTH on osteoblasts...- Long-term strontium ranelate administration in monkeys preserves characteristics of bone mineral crystals and degree of mineralization of boneDelphine Farlay
Laboratoire d'Histodynamique Osseuse, , , Lyon, France
J Bone Miner Res 20:1569-78. 2005.... - Differential effects of teriparatide and alendronate on bone remodeling in postmenopausal women assessed by histomorphometric parametersMonique Arlot
Laboratoire d Histodynamique Osseuse and INSERM Unit 403, Faculty of Medicine R Laennec, Lyon, France
J Bone Miner Res 20:1244-53. 2005..Biopsies were obtained from 42 patients. Indices of bone formation were significantly higher after 6 or 18 months of teriparatide compared with alendronate treatment... - Influence of estrogen therapy at conventional and high doses on the degree of mineralization of iliac bone tissue: a quantitative microradiographic analysis in postmenopausal womenGeorges Boivin
Inserm Unite 403, Faculté de Médecine R Laennec, Université C Bernard Lyon 1, 69372 Lyon Cedex 08, France
Bone 36:562-7. 2005..However, this increase was about two-fold lower than that observed after alendronate therapy (10 mg/day/3 years) in postmenopausal osteoporotic women... - [Comparison of early bone histomorphometric effects of parathormone and alendronate in osteoporotic women]Monique Arlot
INSERM U 403, Laboratoire d histodynamique Faculté Laennec Rue Paradin F 69008 Lyon
Rev Med Suisse Romande 124:91-2. 2004..Theses effects are present at the sixth month... - [New methods to measure bone quality]Jean Paul Roux
INSERM U 403 Faculté de médecine Laennec Rue G Paradin, F 69372 Lyon
Rev Med Suisse Romande 124:71-2. 2004..These determinants are more or less linked to bone turnover, an absence or excessive one increasing bone fragility. Consequently, a minimum but not excessive level of bone turnover must be preserved in osteoporosis treatment... - Methodological considerations in measurement of bone mineral contentGeorges Boivin
Osteoporos Int 14:S22-7; discussion S27-8. 2003 - Quantification of the degree of mineralization of bone in three dimensions using synchrotron radiation microtomographyStefania Nuzzo
CREATIS, 502, INSA, 69621 Villeurbanne Cedex, France
Med Phys 29:2672-81. 2002..5-1.6 g of mineral per cubic centimeter of bone, both in cortical and in trabecular region. The mean difference between the two techniques was around 4.7%, and was slightly higher in trabecular region than in cortical bone... 
Bone sialoprotein plays a functional role in bone formation and osteoclastogenesisLuc Malaval
Institut National de Santé et de Recherche Médicale U890, IFR 143, Université Jean Monnet, Saint Etienne, F42023, France
J Exp Med 205:1145-53. 2008..It does not, however, prevent the bone loss resulting from loss of mechanical stimulation, a phenotype that is clearly different from OPN(-/-) mice...- Infrared imaging of calcified tissue in bone biopsies from adults with osteomalaciaDan Faibish
Hospital for Special Surgery, New York, NY 10021, USA
Bone 36:6-12. 2005.... - Unexpected absence of effect of rhBMP-7 on distraction osteogenesisFrederic Sailhan
Department of Pediatric Orthopaedics, Hôpital Debrousse Lyon, France
Clin Orthop Relat Res 457:227-34. 2007..We suggest the poor results related to the relatively large bulk of the solid carrier of the OP-1 that might have acted as a mechanical obstacle to osteogenesis...