Nathalie Billon

Summary

Country: France

Publications

  1. doi Developmental origins of the adipocyte lineage: new insights from genetics and genomics studies
    Nathalie Billon
    Institut Biologie du Développement et Cancer, CNRS UMR 6543, Faculté de Médecine Pasteur, Universite de Nice Sophia Antipolis, 28 Avenue de Valombrose, 06108, Nice Cedex 2, France
    Stem Cell Rev 8:55-66. 2012
  2. ncbi The generation of adipocytes by the neural crest
    Nathalie Billon
    Institut de Recherche, Signalisation, Biologie du Developpement et Cancer, CNRS UMR 6543, Centre de Biochimie, Faculte des Sciences, université Nice Sophia Antipolis, Nice, France
    Development 134:2283-92. 2007
  3. ncbi Roles for p53 and p73 during oligodendrocyte development
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, London WC1E 6BT, UK
    Development 131:1211-20. 2004
  4. pmc Comprehensive transcriptome analysis of mouse embryonic stem cell adipogenesis unravels new processes of adipocyte development
    Nathalie Billon
    Universite de Nice Sophia Antipolis, Institut Biologie du Développement et Cancer, CNRS UMR 6543, Faculté de Médecine Pasteur, 28 Avenue de Valombrose, 06108 Nice Cedex 2, France
    Genome Biol 11:R80. 2010
  5. doi Developmental origin of adipocytes: new insights into a pending question
    Nathalie Billon
    Institut de Recherche, Signalisation, Biologie du Developpement et Cancer, CNRS UMR 6543, Centre de Biochimie, Faculte des Sciences, université Nice Sophia Antipolis, Nice, France
    Biol Cell 100:563-75. 2008
  6. ncbi Generation and characterization of oligodendrocytes from lineage-selectable embryonic stem cells in vitro
    Nathalie Billon
    Laboratoire cellules souches et différenciation, UMR 6543 CNRS, Centre de Biochimie, Faculté des Sciences Valrose, Nice, France
    Methods Mol Biol 330:15-32. 2006
  7. doi Commitment of mouse embryonic stem cells to the adipocyte lineage requires retinoic acid receptor beta and active GSK3
    Miguel C Monteiro
    Institute of Developmental Biology and Cancer, Centre de Biochimie, Faculte des Sciences, université Nice Sophia Antipolis, Nice, France
    Stem Cells Dev 18:457-63. 2009
  8. ncbi Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit and the Biology Department, University College London, London WC1E 6BT, UK
    J Cell Sci 115:3657-65. 2002
  9. doi PBX1: a novel stage-specific regulator of adipocyte development
    Miguel C Monteiro
    CNRS, IBDC, Nice, France
    Stem Cells 29:1837-48. 2011
  10. pmc Normal timing of oligodendrocyte development depends on thyroid hormone receptor alpha 1 (TRalpha1)
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK
    EMBO J 21:6452-60. 2002

Collaborators

Detail Information

Publications12

  1. doi Developmental origins of the adipocyte lineage: new insights from genetics and genomics studies
    Nathalie Billon
    Institut Biologie du Développement et Cancer, CNRS UMR 6543, Faculté de Médecine Pasteur, Universite de Nice Sophia Antipolis, 28 Avenue de Valombrose, 06108, Nice Cedex 2, France
    Stem Cell Rev 8:55-66. 2012
    ..They suggest that the adipose tissue is composed of distinct mini-organs, exhibiting developmental and functional differences, as well as variable contribution to obesity-related metabolic diseases...
  2. ncbi The generation of adipocytes by the neural crest
    Nathalie Billon
    Institut de Recherche, Signalisation, Biologie du Developpement et Cancer, CNRS UMR 6543, Centre de Biochimie, Faculte des Sciences, université Nice Sophia Antipolis, Nice, France
    Development 134:2283-92. 2007
    ..Finally, we mapped NC derivatives in vivo using Cre-mediated recombination in transgenic mice and demonstrated that a subset of adipocytes originates from the NC during normal development...
  3. ncbi Roles for p53 and p73 during oligodendrocyte development
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit, University College London, London WC1E 6BT, UK
    Development 131:1211-20. 2004
    ..This is the first evidence for a role of p73 in the differentiation of a normal mammalian cell...
  4. pmc Comprehensive transcriptome analysis of mouse embryonic stem cell adipogenesis unravels new processes of adipocyte development
    Nathalie Billon
    Universite de Nice Sophia Antipolis, Institut Biologie du Développement et Cancer, CNRS UMR 6543, Faculté de Médecine Pasteur, 28 Avenue de Valombrose, 06108 Nice Cedex 2, France
    Genome Biol 11:R80. 2010
    ..While major progress has been made in defining the molecular networks that control adipocyte terminal differentiation, the early steps of adipocyte development and the embryonic origin of this lineage remain largely unknown...
  5. doi Developmental origin of adipocytes: new insights into a pending question
    Nathalie Billon
    Institut de Recherche, Signalisation, Biologie du Developpement et Cancer, CNRS UMR 6543, Centre de Biochimie, Faculte des Sciences, université Nice Sophia Antipolis, Nice, France
    Biol Cell 100:563-75. 2008
    ..This review summarizes the surprising findings that have recently emerged from both embryonic stem cells and lineage-tracing studies in vivo, unravelling an unsuspected developmental origin for MSCs and adipocytes in the neural crest...
  6. ncbi Generation and characterization of oligodendrocytes from lineage-selectable embryonic stem cells in vitro
    Nathalie Billon
    Laboratoire cellules souches et différenciation, UMR 6543 CNRS, Centre de Biochimie, Faculté des Sciences Valrose, Nice, France
    Methods Mol Biol 330:15-32. 2006
    ..It may also be useful for producing OPCs and oligodendrocytes from human ES cells for cell therapy and drug screening...
  7. doi Commitment of mouse embryonic stem cells to the adipocyte lineage requires retinoic acid receptor beta and active GSK3
    Miguel C Monteiro
    Institute of Developmental Biology and Cancer, Centre de Biochimie, Faculte des Sciences, université Nice Sophia Antipolis, Nice, France
    Stem Cells Dev 18:457-63. 2009
    ..Our results suggest that although RARbeta and active GSK3 are required for RA-induced adipogenesis, they might be acting through a Wnt pathway-independent mechanism...
  8. ncbi Normal timing of oligodendrocyte development from genetically engineered, lineage-selectable mouse ES cells
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology and Cell Biology Unit and the Biology Department, University College London, London WC1E 6BT, UK
    J Cell Sci 115:3657-65. 2002
    ..This strategy may also be useful for producing human cells for therapy and drug screening...
  9. doi PBX1: a novel stage-specific regulator of adipocyte development
    Miguel C Monteiro
    CNRS, IBDC, Nice, France
    Stem Cells 29:1837-48. 2011
    ....
  10. pmc Normal timing of oligodendrocyte development depends on thyroid hormone receptor alpha 1 (TRalpha1)
    Nathalie Billon
    MRC Laboratory for Molecular Cell Biology, University College London, London WC1E 6BT, UK
    EMBO J 21:6452-60. 2002
    ..Finally, we provide evidence that the inhibitory isoforms of TRalpha are unlikely to play a part in the timing of OPC differentiation...
  11. ncbi Nucleofection is a valuable transfection method for transient and stable transgene expression in adipose tissue-derived stem cells
    Laure Emmanuelle Zaragosi
    Institut de Recherche, Signalisation, Biologie du Developpement et Cancer, CNRS UMR6543, Centre de Biochimie, Faculte des Sciences, université Nice Sophia Antipolis, 06108 Nice Cedex 2, France
    Stem Cells 25:790-7. 2007
    ..Taken together, our data demonstrate that nucleofection allows both transient and stable gene expression in adipose tissue-derived stem cells, without impairing their differentiation potential...
  12. ncbi A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction
    Pascale Perry
    Lymphocyte Development Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, London, UK
    Cell Cycle 3:1645-50. 2004
    ..These results show that loss of pluripotency (and lineage choice) is associated with extensive and predictable changes in the replication timing of key regulator genes...