M Billiard

Summary

Country: France

Publications

  1. pmc Narcolepsy: current treatment options and future approaches
    Michel Billiard
    Department of Neurology, Gui de Chauliac Hospital Montpellier, France
    Neuropsychiatr Dis Treat 4:557-66. 2008
  2. ncbi request reprint [Fatigue and sleep disorders of patients with colorectal cancer]
    M Billiard
    Departement de Neurologie, Hopital Gui de Chauliac, 80, avenue Augustin Fliche, 34295 Montpellier Cedex 5, France Electronic address
    Pathol Biol (Paris) 61:e83-7. 2013
  3. doi request reprint Recurrent hypersomnia following traumatic brain injury
    Michel Billiard
    Department of Neurology, Gui de Chauliac Hospital, Montpellier, France
    Sleep Med 14:462-5. 2013
  4. ncbi request reprint [Hypocretin disturbance and sleep disorders]
    Michel Billiard
    Neurologie, Hopital Gui de Chauliac, 80, avenue Augustin Fliche, 34295 Montpellier Cedex
    Bull Acad Natl Med 195:1567-78; discussion 1579-81. 2011
  5. ncbi request reprint [Disorders of awakening. Second part: secondary disorders]
    M Billiard
    Service de Neurologie B, Hopital Gui de Chauliac, 34295 Montpellier Cedex 5
    Rev Neurol (Paris) 157:480-96. 2001
  6. ncbi request reprint [Modafinil: pharmacology and therapeutic perspectives]
    M Billiard
    Service de Neurologie B, Hopital Gui de Chauliac, Montpellier
    Rev Neurol (Paris) 159:122-5. 2003
  7. ncbi request reprint EFNS guidelines on management of narcolepsy
    M Billiard
    School of Medicine, University of Montpellier, Montpellier, France
    Eur J Neurol 13:1035-48. 2006
  8. ncbi request reprint Diagnosis of narcolepsy and idiopathic hypersomnia. An update based on the International classification of sleep disorders, 2nd edition
    Michel Billiard
    Department of Neurology, Gui de Chauliac Hospital, 80 Augustin Fliche Avenue, 34295 Montpellier, Cedex 5, France
    Sleep Med Rev 11:377-88. 2007
  9. ncbi request reprint [Excessive daytime sleepiness]
    Michel Billiard
    Departement de Neurologie, Hopital Gui de Chauliac, 34295 Montpellier Cedex 5
    Rev Prat 57:1555-64. 2007
  10. ncbi request reprint REM sleep behavior disorder and narcolepsy
    Michel Billiard
    Gui de Chauliac Hospital, Department of Neurology, Montpellier, France
    CNS Neurol Disord Drug Targets 8:264-70. 2009

Detail Information

Publications48

  1. pmc Narcolepsy: current treatment options and future approaches
    Michel Billiard
    Department of Neurology, Gui de Chauliac Hospital Montpellier, France
    Neuropsychiatr Dis Treat 4:557-66. 2008
    ....
  2. ncbi request reprint [Fatigue and sleep disorders of patients with colorectal cancer]
    M Billiard
    Departement de Neurologie, Hopital Gui de Chauliac, 80, avenue Augustin Fliche, 34295 Montpellier Cedex 5, France Electronic address
    Pathol Biol (Paris) 61:e83-7. 2013
    ....
  3. doi request reprint Recurrent hypersomnia following traumatic brain injury
    Michel Billiard
    Department of Neurology, Gui de Chauliac Hospital, Montpellier, France
    Sleep Med 14:462-5. 2013
    ....
  4. ncbi request reprint [Hypocretin disturbance and sleep disorders]
    Michel Billiard
    Neurologie, Hopital Gui de Chauliac, 80, avenue Augustin Fliche, 34295 Montpellier Cedex
    Bull Acad Natl Med 195:1567-78; discussion 1579-81. 2011
    ..One of the most controversial issues is the functional relevance of partial hypocretin defects in these disorders...
  5. ncbi request reprint [Disorders of awakening. Second part: secondary disorders]
    M Billiard
    Service de Neurologie B, Hopital Gui de Chauliac, 34295 Montpellier Cedex 5
    Rev Neurol (Paris) 157:480-96. 2001
    ..Disorders of awakening secondary to neurologic conditions and to a lesser extent to infectious conditions offer a special opportunity to study the anatomical basis of these disorders. They are granted more space...
  6. ncbi request reprint [Modafinil: pharmacology and therapeutic perspectives]
    M Billiard
    Service de Neurologie B, Hopital Gui de Chauliac, Montpellier
    Rev Neurol (Paris) 159:122-5. 2003
  7. ncbi request reprint EFNS guidelines on management of narcolepsy
    M Billiard
    School of Medicine, University of Montpellier, Montpellier, France
    Eur J Neurol 13:1035-48. 2006
    ..Our objective was to reinforce the use of those drugs evaluated in randomized placebo-controlled trials and to reach a consensus, as much as possible, on the use of other available medications...
  8. ncbi request reprint Diagnosis of narcolepsy and idiopathic hypersomnia. An update based on the International classification of sleep disorders, 2nd edition
    Michel Billiard
    Department of Neurology, Gui de Chauliac Hospital, 80 Augustin Fliche Avenue, 34295 Montpellier, Cedex 5, France
    Sleep Med Rev 11:377-88. 2007
    ..hypersomnia without long sleep time, two forms of the same condition or two different conditions? Is there a pathophysiological relationship between narcolepsy without cataplexy and idiopathic hypersomnia without long sleep time?..
  9. ncbi request reprint [Excessive daytime sleepiness]
    Michel Billiard
    Departement de Neurologie, Hopital Gui de Chauliac, 34295 Montpellier Cedex 5
    Rev Prat 57:1555-64. 2007
    ..New treatments are currently available or in preparation in the case of narcolepsy...
  10. ncbi request reprint REM sleep behavior disorder and narcolepsy
    Michel Billiard
    Gui de Chauliac Hospital, Department of Neurology, Montpellier, France
    CNS Neurol Disord Drug Targets 8:264-70. 2009
    ..However, in the absence of any pharmacological trials of these drugs on RBD in narcoleptic patients, it is difficult to provide guidance other than to recommend conventional treatments of RBD...
  11. doi request reprint Recurrent hypersomnia: a review of 339 cases
    Michel Billiard
    Department of Neurology, Gui de Chauliac Hospital, 80 avenue Augustin Fliche, 34295 Montpellier Cedex 5, France
    Sleep Med Rev 15:247-57. 2011
    ....
  12. ncbi request reprint Is insomnia best categorized as a symptom or a disease?
    Michel Billiard
    Faculty of Medicine, Gui de Chauliac Hospital, Montpellier, France
    Sleep Med 5:S35-40. 2004
    ..Here, we highlight some of the major challenges for future research in classifying both primary insomnia and insomnia related to or associated with various conditions, and their relevance to primary care...
  13. ncbi request reprint A monozygotic twin pair discordant for narcolepsy and CSF hypocretin-1
    Y Dauvilliers
    Neurology B, Sleep Wake Disorder Center, Gui de Chauliac Hospital, Montpellier, France
    Neurology 62:2137-8. 2004
  14. ncbi request reprint Kleine-Levin syndrome: an autoimmune hypothesis based on clinical and genetic analyses
    Y Dauvilliers
    Neurologie B, Hopital Gui de Chauliac, Montpellier, France
    Neurology 59:1739-45. 2002
    ..Pathophysiologic hypotheses include a hypothalamic dysfunction and abnormalities in the central serotonin and dopamine metabolism. Several clinical symptoms also suggest an underlying autoimmune process...
  15. ncbi request reprint Sleep architecture, slow wave activity, and sleep spindles in adult patients with sleepwalking and sleep terrors
    F Espa
    INSERM E 9930, CRLC Val d Aurelle, 34298, Montpellier, France
    Clin Neurophysiol 111:929-39. 2000
    ....
  16. ncbi request reprint [Physiopathology of idiopathic hypersomnia. Current studies and new orientations]
    M Billiard
    Service de Neurologie B, , 34295 Montpellier
    Rev Neurol (Paris) 157:S101-6. 2001
    ....
  17. ncbi request reprint Sexual dimorphism of the catechol-O-methyltransferase gene in narcolepsy is associated with response to modafinil
    Y Dauvilliers
    Neurologie B, Hĵpital Gui de Chauliac, Montpellier, France
    Pharmacogenomics J 2:65-8. 2002
    ..Our results suggest that a sexual dimorphism in COMT activity affects the response to modafinil and probably to other dopaminergic stimulants...
  18. ncbi request reprint Age at onset of narcolepsy in two large populations of patients in France and Quebec
    Y Dauvilliers
    Service de Neurologie B, Unite des troubles du sommeil, Hopital Gui de Chauliac, Montpellier, France
    Neurology 57:2029-33. 2001
    ..Narcolepsy usually starts around adolescence; however, there is great variability in the clinical presentation of narcolepsy...
  19. ncbi request reprint Dissociation in circadian rhythms in a pseudohypersomnia form of fatal familial insomnia
    Y Dauvilliers
    Service de Neurologie B, Hopital Gui de Chauliac, 80 avenue Augustin Fliche, 34295 Montpellier Cedex 5, France
    Neurology 63:2416-8. 2004
    ..There was profound alteration in the sleep-wake cycle with a clear dissociation in the disappearance of circadian and neuroendocrine rhythms, findings unrelated to abnormalities in the hypocretinergic system...
  20. pmc CSF hypocretin-1 levels in narcolepsy, Kleine-Levin syndrome, and other hypersomnias and neurological conditions
    Y Dauvilliers
    Service de Neurologie B, Hopital Gui de Chauliac, Montpellier, France
    J Neurol Neurosurg Psychiatry 74:1667-73. 2003
    ..To determine the role of CSF hypocretin-1 in narcolepsy with and without cataplexy, Kleine-Levin syndrome (KLS), idiopathic and other hypersomnias, and several neurological conditions...
  21. ncbi request reprint [Immunological aspects of narcolepsy]
    B Carlander
    Service de Neurologie B, Hopital Gui de Chauliac, 34295 Montpellier
    Rev Neurol (Paris) 157:S97-100. 2001
    ....
  22. ncbi request reprint [Wake disorders. I. Primary wake disorders]
    M Billiard
    Service de Neurologie B, , Montpellier
    Rev Neurol (Paris) 154:111-29. 1998
    ..On the other hand a prophylactic treatment with carbamazepine or lithium may be active. Pathophysiology remains unsettled in spite of some evidence of a hypothalamic functional disturbance...
  23. ncbi request reprint Dose-response effects of zopiclone on night sleep and on nighttime and daytime functioning
    M Billiard
    Service de Physiopathologie des Maladies Nerveuses et Musculaires, Centre Gui de Chauliac, Montpellier, France
    Sleep 10:27-34. 1987
    ..Side effects (bitter taste, jitteriness, difficulty to concentrate) were reported only with 7.5 mg zopiclone...
  24. ncbi request reprint [Arousal of respiratory origin and upper airway resistance syndrome: pathophysiological and diagnostic aspects]
    F J Puertas
    Centro de Trastornos del Sueño y la Vigilia, Hopital Gui de Chauliac, Montpellier, Francia
    Rev Neurol 28:565-72. 1999
    ..The description of Upper Airway Resistance Syndrome (UARS) let us to recognize the importance of the pair 'respiratory effort-arousal' on sleep-disordered breathing pathophysiology...
  25. ncbi request reprint [Advanced sleep phase syndrome]
    B Ondze
    Service de Neurologie B, Unité des Troubles du Sommeil et de l Eveil, Hopital Gui de Chauliac, 80, Av Augustin Fliche, 34295 Montpellier
    Rev Neurol (Paris) 157:S130-4. 2001
    ..These data show the difficulties of the management and the treatment of this rarely diagnosed disease...
  26. ncbi request reprint Modafinil: a double-blind multicentric study
    M Billiard
    Service de Neurologie B, , Montpellier, France
    Sleep 17:S107-12. 1994
    ..Feeling on awakening was not modified. An overall benefit was noted by physicians as well as by patients. MWT disclosed a positive effect of modafinil on excessive daytime sleepiness. Cataplexy was not modified...
  27. ncbi request reprint Sleep in human narcolepsy revisited with special reference to prior wakefulness duration
    M Tafti
    Sleep and Wake Disorders Unit, Gui-de-Chauliac Hospital, Montpellier, France
    Sleep 15:344-51. 1992
    ..We hypothesize that this could reflect an alteration of the homeostatic process of sleep regulation in narcolepsy...
  28. ncbi request reprint Effect of age on MSLT results in patients with narcolepsy-cataplexy
    Y Dauvilliers
    Centre d Etude du Sommeil, Hopital Gui de Chauliac, and INSERM E 0361, Hôpital La Colombière, Montpellier, France
    Neurology 62:46-50. 2004
    ..To measure the effect of age on Multiple Sleep Latency Test (MSLT)characteristics, sleep latency, and number of sleep-onset REM periods (SOREMP) in two large populations of narcoleptic patients with similar genetic backgrounds...
  29. ncbi request reprint Family studies in narcolepsy
    M Billiard
    Service de Neurologie B, , Montpellier, France
    Sleep 17:S54-9. 1994
    ..A trend in favor of a more frequent transmission through mothers than fathers is emphasized...
  30. ncbi request reprint Life events in the year preceding the onset of narcolepsy
    C Orellana
    Service de Neurologie B, , Montpellier, France
    Sleep 17:S50-3. 1994
    ..However a number of other factors could not be taken into consideration, which limits the full significance of these data...
  31. ncbi request reprint Homeostasis and narcolepsy
    A Besset
    Service de Neurologie B, Centre Gui de Chauliac, Montpellier, France
    Sleep 17:S29-34. 1994
    ....
  32. ncbi request reprint Sleep architecture, slow wave activity and sleep spindles in mild sleep disordered breathing
    B Ondze
    Service de Neurologie, Unité des Troubles du Sommeil et de l Eveil, Hôpital Gui de Chauliac B34295 Montpellier, Cedex 5, France
    Clin Neurophysiol 114:867-74. 2003
    ....
  33. ncbi request reprint Excessive daytime somnolence in young men: prevalence and contributing factors
    M Billiard
    , Montpellier, France
    Sleep 10:297-305. 1987
    ..All five factors were shown to be independently related to excessive daytime somnolence and were ranked in the following descending order: use of hypnotics, sleep difficulties, irregular sleep-wake schedule, snoring, and hours of sleep...
  34. ncbi request reprint [Genetics of human narcolepsy]
    Y Dauvilliers
    Service de Neurologie B, 80, avenue Augustin Fliche, , 34295 Montpellier, France
    Rev Neurol (Paris) 157:S92-6. 2001
    ..An autoimmune process is probable...
  35. ncbi request reprint [Staphylococcal toxic syndrome, atypical presentation of Kawasaki syndrome or staphylococcal skin syndrome?]
    M H Odievre
    Service de Pediatrie Generale, Hopital Louis Mourier, 178, rue des Renouillers, 92701 Colombes, France
    Arch Pediatr 9:155-8. 2002
    ..A TSS-positive Staphylococcus aureus strain was isolated from the abscess...
  36. ncbi request reprint MAO-A and COMT polymorphisms and gene effects in narcolepsy
    Y Dauvilliers
    Neurologie B, Hopital Gui de Chauliac, Montpellier France, France
    Mol Psychiatry 6:367-72. 2001
    ..In agreement with well-documented pharmacological results in canine narcolepsy, this study reports the first genetic evidence for the critical involvement of the dopaminergic and/or noradrenergic systems in human narcolepsy...
  37. ncbi request reprint Severity of narcolepsy among French of different ethnic origins (south of France and Martinique)
    Yves Dauvilliers
    Sleep and Wake Disorder Center Neurology B Unit, Gui de Chauliac Hospital, Montpellier, France
    Sleep 25:50-5. 2002
    ..The aim of the study was to describe the clinical and polygraphical characteristics of narcoleptics, with and without cataplexy and to assess HLA predisposition across two different ethnic populations...
  38. ncbi request reprint [Narcolepsy, from Westphal to hypocretin]
    Yves Dauvilliers
    Faculte de Medecine, Hopital Gui de Chauliac, Montpellier
    Presse Med 33:1593-600. 2004
    ..Current therapeutic research is oriented towards hypocretin agonists and immunosuppressors...
  39. ncbi request reprint Effect of cognitive behavioural therapy for insomnia on sleep architecture and sleep EEG power spectra in psychophysiological insomnia
    Katerina Cervena
    Sleep and wake disorder unit, Gui de Chauliac Hospital, Montpellier, France
    J Sleep Res 13:385-93. 2004
    ..In conclusion CBT-I improves both subjective and objective sleep quality of sleep. CBT-I may enhance sleep pressure and improve homeostatic sleep regulation...
  40. ncbi request reprint [Introduction. Neurodegenerative diseases and sleep]
    M Billiard
    Service de Neurologie B, Hopital Gui de Chauliac, Montpellier
    Rev Neurol (Paris) 159:6S56-8. 2003
  41. ncbi request reprint Family studies in insomnia
    Yves Dauvilliers
    Service de Neurologie B, Hopital Gui de Chauliac, 80 avenue Augustin Fliche, Montpellier Cedex 5 34295, France
    J Psychosom Res 58:271-8. 2005
    ..The aim of this study is to evaluate the prevalence of insomnia among first-degree relatives of chronic insomniacs and to compare the symptoms between sporadic and familial insomnia...
  42. ncbi request reprint Month of birth as a risk factor for narcolepsy
    Yves Dauvilliers
    Service de Neurologie B, Unite des troubles du sommeil, Hôpital Gui de Chauliac Montpellier, France
    Sleep 26:663-5. 2003
    ..The aim of the study was to find out whether there is a seasonality of month of birth in narcoleptic patients...
  43. ncbi request reprint A narcolepsy susceptibility locus maps to a 5 Mb region of chromosome 21q
    Yves Dauvilliers
    Service de Neurologie B, Hopital Gui de Chauliac, Montpellier, France
    Ann Neurol 56:382-8. 2004
    ..15 Mb region of 21q...
  44. ncbi request reprint Clinical aspects and pathophysiology of narcolepsy
    Yves Dauvilliers
    Service de Neurologie B, Hopital Gui de Chauliac, 80 avenue Augustin Fliche, 34295 Montpellier Cedex 5, France
    Clin Neurophysiol 114:2000-17. 2003
    ..However, other lines of research deserve to be pursued simultaneously, in view of comprehensive advancements in the understanding of narcolepsy...
  45. ncbi request reprint Awakening from sleep
    Torbjorn Akerstedt
    Karolinska Institute, Stockholm, Sweden
    Sleep Med Rev 6:267-86. 2002
    ..Daytime functioning is shown in insomniac patients and compared to other pathologies like sleep apnea. A final section evokes links between some types of night waking and psychological factors...
  46. ncbi request reprint [Methadone and sleep apnea syndrome]
    Philippe Durst
    Centre Hospitalier Sainte Marie, Réseau ERAHSM, Privas, France
    Can J Psychiatry 50:153-8. 2005
    ..Sleep is fitful, broken by arousals, and yields little rest. There is daytime excessive sleepiness with repeated involuntary falling asleep, often unknown by the subject...
  47. ncbi request reprint The Kleine-Levin syndrome: a paramedian thalamic dysfunction?
    Michel Billiard
    Sleep 28:915-6. 2005
  48. ncbi request reprint Arousal reactions in sleepwalking and night terrors in adults: the role of respiratory events
    Fabrice Espa
    INSERM EMI 9930, Hôpital La Colombière, 34093 Montpellier Cedex 5 France
    Sleep 25:871-5. 2002
    ..The aim of the study was to determine the role of respiratory events, assessed by means of esophageal pressure monitoring, during arousals from slow wave sleep in adult patients with parasomnias...