Research Topics
Species | Catalina BetancurSummaryCountry: France Publications
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Publications
Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral featuresJoseph D Buxbaum
Seaver Autism Center for Research and Treatment, Mount Sinai School of Medicine, One Gustave L Levy Place, New York, NY 10029, USA
Mol Autism 3:1. 2012..abstract:..
A large-scale survey of the novel 15q24 microdeletion syndrome in autism spectrum disorders identifies an atypical deletion that narrows the critical regionL Alison McInnes
Seaver Autism Center for Research and Treatment, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA
Mol Autism 1:5. 2010..In this study we surveyed two ASD cohorts for 15q24 abnormalities to assess the frequency of genomic imbalances in this interval...
Mutation screening of NOS1AP gene in a large sample of psychiatric patients and controlsRichard Delorme
Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France
BMC Med Genet 11:108. 2010..Previous genetic and functional studies explored the role of NOS1AP in these psychiatric conditions, but only a limited number explored the sequence variability of NOS1AP...
Search for copy number variants in chromosomes 15q11-q13 and 22q11.2 in obsessive compulsive disorderRichard Delorme
INSERM, U955, Institut Mondor de Recherche Biomedicale, PsychiatricGenetics, Creteil, France
BMC Med Genet 11:100. 2010..Therefore, the aim of this study was to search for microrearrangements in these two regions in OCD patients...
Etiological heterogeneity in autism spectrum disorders: more than 100 genetic and genomic disorders and still countingCatalina Betancur
INSERM, U952, Universite Pierre et Marie Curie, Paris, France
Brain Res 1380:42-77. 2011..Finally, the data provide strong support for high-resolution DNA microarrays as well as whole-exome and whole-genome sequencing as critical approaches for identifying the genetic causes of ASDs...
Platelet serotonergic markers as endophenotypes for obsessive-compulsive disorderRichard Delorme
INSERM U 513, Faculte de Medecine, Creteil, France
Neuropsychopharmacology 30:1539-47. 2005..These alterations may serve as endophenotypic markers in OCD, and could contribute to the study of the biological mechanisms and genetic underpinnings of the disorder...
Shared executive dysfunctions in unaffected relatives of patients with autism and obsessive-compulsive disorderRichard Delorme
INSERM U513, Neurobiologie et Psychiatrie, Universite Paris XII, Creteil, France
Eur Psychiatry 22:32-8. 2007....
No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjectsRichard Delorme
Human Genetics and Cognitive Functions, Pasteur Institute, Paris, France
Biol Psychiatry 60:202-3. 2006..1.4% in control subjects)...
Exploratory analysis of obsessive compulsive symptom dimensions in children and adolescents: a prospective follow-up studyRichard Delorme
INSERM U513, Faculte de Medecine, Universite Paris XII, Creteil, France
BMC Psychiatry 6:1. 2006..Although a phenotypic continuum from childhood to adulthood has been hypothesized, no factor analytic studies have been performed in juvenile patients, and the stability of OC dimensions in children and adolescents has not been assessed...
Analysis of X chromosome inactivation in autism spectrum disordersXiaohong Gong
Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France
Am J Med Genet B Neuropsychiatr Genet 147:830-5. 2008..We propose that the XCI profile could be a useful criteria to prioritize families for mutation screening of X-linked candidate genes...
An investigation of ribosomal protein L10 gene in autism spectrum disordersXiaohong Gong
Human Genetics and Cognitive Functions, CNRS URA 2182 Genes, Synapses and Cognition, Institut Pasteur, Paris, France
BMC Med Genet 10:7. 2009..To confirm these initial findings, we re-sequenced RPL10 exons and quantified mRNA transcript level of RPL10 in our samples...
Loss of VGLUT1 and VGLUT2 in the prefrontal cortex is correlated with cognitive decline in Alzheimer diseaseAlireza Kashani
INSERM, U513, 94000 Creteil, France
Neurobiol Aging 29:1619-30. 2008..Our results suggest that VGLUT1 expression in the prefrontal cortex could be used as a valuable neurochemical marker of dementia in AD...
Screening for genomic rearrangements and methylation abnormalities of the 15q11-q13 region in autism spectrum disordersChristel Depienne
INSERM U679, AP HP, Groupe Hospitalier Pitie Salpetriere, Paris, France
Biol Psychiatry 66:349-59. 2009..However, the prevalence of these disorders in ASD is unknown. The aim of this study was to assess the frequency of 15q11-q13 rearrangements in a large sample of patients ascertained for ASD...
The emerging role of synaptic cell-adhesion pathways in the pathogenesis of autism spectrum disordersCatalina Betancur
INSERM U, Universite Pierre et Marie Curie, Paris, France
Trends Neurosci 32:402-12. 2009....
Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disordersChristelle M Durand
Human Genetics and Cognitive Functions, Institut Pasteur, Paris, France
Nat Genet 39:25-7. 2007..These mutations concern only a small number of individuals, but they shed light on one gene dosage-sensitive synaptic pathway that is involved in autism spectrum disorders...
