- Predisposing gene for early-onset prostate cancer, localized on chromosome 1q42.2-43P Berthon
Département d urologie, Universite Paris VII, Hopital Saint Louis, Paris, France
Am J Hum Genet 62:1416-24. 1998..Furthermore, the 9/47 families with early-onset CaP at age <60 years gave multipoint LOD and NPL scores of 3.31 and 3.32, respectively, with P = .001...
- Constitutive expression of FGF2/bFGF in non-tumorigenic human prostatic epithelial cells results in the acquisition of a partial neoplastic phenotypeF Ropiquet
Laboratoire de Biologie Hormonale, Hopital St Louis, Paris, France
Int J Cancer 72:543-7. 1997..Such results argue in favor of the possible action of FGF2 on progression of prostate cancer via an FGF2 autocrine loop on epithelial cells...
- Androgens are not a direct requirement for the proliferation of human prostatic epithelium in vitroP Berthon
Département d urologie, Hopital Saint Louis, Paris, France
Int J Cancer 73:910-6. 1997....
- Hereditary prostate cancer and other genetic predispositions to prostate cancerO Cussenot
Département d urologie, Universite Paris VII, Hopital Saint Louis, France
Urol Int 60:30-4; discussion 35. 1998..Candidate genes may be the same suppressor genes that are involved in other cancers and in sporadic CaP...
- Early-onset hereditary prostate cancer is not associated with specific clinical and biological featuresA Valeri
Centre de Recherche pour les Pathologies Prostatiques, UPRES EA3104, Universite Paris VII, Evry, France
Prostate 45:66-71. 2000..Familial prostate cancer (CaP) accounts for 15-20% of all CaP, and hereditary CaP for 5-10% of patients. Few data are available concerning their clinical and biological features...
- Evaluation and clinical value of neuroendocrine differentiation in human prostatic tumorsO Cussenot
Department of Urologie, Hopital Saint Louis, and Université Paris, France
Prostate Suppl 8:43-51. 1998..However, on the basis of experimental data, neuroendocrine-like cells appear to be involved in the emergence of androgen-independent cells and could be a target for new prostate cancer therapeutic strategies...
- Immunocytochemical comparison of cultured normal epithelial prostatic cells with prostatic tissue sectionsO Cussenot
Département de Recherche en Urologie, Hopital Saint Louis, Paris, France
Exp Cell Res 214:83-92. 1994....
- Evaluation of androgen, estrogen (ER alpha and ER beta), and progesterone receptor expression in human prostate cancer by real-time quantitative reverse transcription-polymerase chain reaction assaysA Latil
CeRePP, Universite Paris VII, Evry, France
Cancer Res 61:1919-26. 2001..Our results also suggest that ER alpha and ER beta expression status could be used to identify advanced prostate tumor patients who may respond to antiestrogen therapy...