Said Bendahhou

Summary

Country: France

Publications

  1. ncbi Corticosteroid-exacerbated symptoms in an Andersen's syndrome kindred
    Said Bendahhou
    Institut de Pharmacologie Moleculaire et Cellulaire, UMR 6097 CNRS, Universite de Nice Sophia Antipolis, France
    Hum Mol Genet 16:900-6. 2007
  2. ncbi Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome
    Said Bendahhou
    Department of Human Molecular Biology and Genetics, University of Utah, Salt Lake City, Utah 84112, USA
    J Biol Chem 278:51779-85. 2003
  3. ncbi In vivo and in vitro functional characterization of Andersen's syndrome mutations
    Said Bendahhou
    Universite de Nice Sophia Antipolis, UMR 6097 CNRS, Institut de Pharmacologie Moleculaire et Cellulaire, 660 route des Lucioles, Sophia Antipolis, 06560 Valbonne, France
    J Physiol 565:731-41. 2005
  4. ncbi In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart
    Said Bendahhou
    Institut de Pharmacologie Moleculaire et Cellulaire, UMR 6097 CNRS and Université de Nice Sophia Antipolis, 660 route des Lucioles, Sophia Antipolis, 06560 Valbonne, France
    Cardiovasc Res 67:529-38. 2005
  5. ncbi Potassium channel silencing by constitutive endocytosis and intracellular sequestration
    Sylvain Feliciangeli
    Institut de Pharmacologie Moleculaire et Cellulaire, CNRS, and Université de Nice Sophia Antipolis, Sophia Antipolis, 06560 Valbonne, France
    J Biol Chem 285:4798-805. 2010
  6. ncbi TWIK1, a unique background channel with variable ion selectivity
    Franck C Chatelain
    Institut de Pharmacologie Moleculaire et Cellulaire, Centre National de la Recherche Scientifique, and Université de Nice Sophia Antipolis, 06560 Valbonne, France
    Proc Natl Acad Sci U S A 109:5499-504. 2012
  7. ncbi Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)
    Martin Tristani-Firouzi
    Division of Pediatric Cardiology, University of Utah, Salt Lake City, Utah 84112, USA
    J Clin Invest 110:381-8. 2002
  8. ncbi Does sumoylation control K2P1/TWIK1 background K+ channels?
    Sylvain Feliciangeli
    Institut de Pharmacologie Moleculaire et Cellulaire, CNRS UMR6097, Institut Paul Hamel, 660, route des Lucioles, 06560 Valbonne, France
    Cell 130:563-9. 2007
  9. ncbi Role of hydrophobic residues in the voltage sensors of the voltage-gated sodium channel
    Said Bendahhou
    Institut de Pharmacologie Moleculaire et Cellulaire, UMR 6097 CNRS, Universite de Nice, Sophia Antipolis 660 Route des Lucioles, Sophia Antipolis, Valbonne, France
    Biochim Biophys Acta 1768:1440-7. 2007
  10. ncbi ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6
    Sonia Decressac
    Institut de Pharmacologie Moleculaire et Cellulaire, CNRS UMR6097 UNSA, Institut Paul Hamel, 660, route des Lucioles, 06560 Valbonne, France
    EMBO Rep 5:1171-5. 2004

Collaborators

  • Richard Warth
  • Florian Lesage
  • Louis J Ptacek
  • Delphine Bichet
  • Giovanni Meola
  • Herve Duclohier
  • Sylvain Feliciangeli
  • Jacques Barhanin
  • Franck C Chatelain
  • Markus Reichold
  • Guillaume Sandoz
  • Michel Lazdunski
  • Sonia Decressac
  • Martin Tristani-Firouzi
  • Dominique Douguet
  • Magalie P Tardy
  • Pierre Gounon
  • Sebastian Knauer
  • Michel Franco
  • Anna Fidzianska
  • Hubert Kwiecinski
  • Matthew R Donaldson
  • Ying-Hui Fu
  • Angelika Hahn
  • Rabi Tawil
  • Judy L Jensen
  • Valeria Sansone
  • Nikki Plaster
  • Ying Hui Fu

Detail Information

Publications10

  1. ncbi Corticosteroid-exacerbated symptoms in an Andersen's syndrome kindred
    Said Bendahhou
    Institut de Pharmacologie Moleculaire et Cellulaire, UMR 6097 CNRS, Universite de Nice Sophia Antipolis, France
    Hum Mol Genet 16:900-6. 2007
    ..Taken together, our data suggest the inclusion of the KCNJ2 gene in the molecular screening of patients with periodic paralysis, even when the classical AS dysmorphic features are not present...
  2. ncbi Defective potassium channel Kir2.1 trafficking underlies Andersen-Tawil syndrome
    Said Bendahhou
    Department of Human Molecular Biology and Genetics, University of Utah, Salt Lake City, Utah 84112, USA
    J Biol Chem 278:51779-85. 2003
    ....
  3. ncbi In vivo and in vitro functional characterization of Andersen's syndrome mutations
    Said Bendahhou
    Universite de Nice Sophia Antipolis, UMR 6097 CNRS, Institut de Pharmacologie Moleculaire et Cellulaire, 660 route des Lucioles, Sophia Antipolis, 06560 Valbonne, France
    J Physiol 565:731-41. 2005
    ..We hypothesize that Andersen's syndrome-associated mutations and hypokalaemic periodic paralysis-associated calcium channel mutations may lead to muscle membrane hypoexcitability via a common mechanism...
  4. ncbi In vitro molecular interactions and distribution of KCNE family with KCNQ1 in the human heart
    Said Bendahhou
    Institut de Pharmacologie Moleculaire et Cellulaire, UMR 6097 CNRS and Université de Nice Sophia Antipolis, 660 route des Lucioles, Sophia Antipolis, 06560 Valbonne, France
    Cardiovasc Res 67:529-38. 2005
    ..The expression level and the putative functions of the different KCNE subunits in the human heart still require further investigation...
  5. ncbi Potassium channel silencing by constitutive endocytosis and intracellular sequestration
    Sylvain Feliciangeli
    Institut de Pharmacologie Moleculaire et Cellulaire, CNRS, and Université de Nice Sophia Antipolis, Sophia Antipolis, 06560 Valbonne, France
    J Biol Chem 285:4798-805. 2010
    ....
  6. ncbi TWIK1, a unique background channel with variable ion selectivity
    Franck C Chatelain
    Institut de Pharmacologie Moleculaire et Cellulaire, Centre National de la Recherche Scientifique, and Université de Nice Sophia Antipolis, 06560 Valbonne, France
    Proc Natl Acad Sci U S A 109:5499-504. 2012
    ..TWIK1(-/-) pancreatic β cells are more polarized than control cells, confirming a depolarizing role of TWIK1 in kidney and pancreatic cells...
  7. ncbi Functional and clinical characterization of KCNJ2 mutations associated with LQT7 (Andersen syndrome)
    Martin Tristani-Firouzi
    Division of Pediatric Cardiology, University of Utah, Salt Lake City, Utah 84112, USA
    J Clin Invest 110:381-8. 2002
    ..These findings suggest that the substrate for arrhythmia susceptibility in AS is distinct from the other forms of inherited LQT syndrome...
  8. ncbi Does sumoylation control K2P1/TWIK1 background K+ channels?
    Sylvain Feliciangeli
    Institut de Pharmacologie Moleculaire et Cellulaire, CNRS UMR6097, Institut Paul Hamel, 660, route des Lucioles, 06560 Valbonne, France
    Cell 130:563-9. 2007
    ..Furthermore, we failed to observe any band shift by western blot analysis that would confirm an eventual sumoylation of K2P1 in COS-7 cells and oocytes...
  9. ncbi Role of hydrophobic residues in the voltage sensors of the voltage-gated sodium channel
    Said Bendahhou
    Institut de Pharmacologie Moleculaire et Cellulaire, UMR 6097 CNRS, Universite de Nice, Sophia Antipolis 660 Route des Lucioles, Sophia Antipolis, Valbonne, France
    Biochim Biophys Acta 1768:1440-7. 2007
    ..The two mutated residues are closer to each other in domains I and II than in domain III, as may be corroborated by their different electrophysiological effects...
  10. ncbi ARF6-dependent interaction of the TWIK1 K+ channel with EFA6, a GDP/GTP exchange factor for ARF6
    Sonia Decressac
    Institut de Pharmacologie Moleculaire et Cellulaire, CNRS UMR6097 UNSA, Institut Paul Hamel, 660, route des Lucioles, 06560 Valbonne, France
    EMBO Rep 5:1171-5. 2004
    ..EFA6 interacts with TWIK1 only when it is bound to ARF6. Because ARF6 modulates endocytosis at the apical surface of epithelial cells, the ARF6/EFA6/TWIK1 association is probably important for channel internalization and recycling...