A Benazzouz

Summary

Country: France

Publications

  1. ncbi Implication of the subthalamic nucleus in the pathophysiology and pathogenesis of Parkinson's disease
    A Benazzouz
    Laboratoire de Neurobiologie Preclinique, INSERM U 318, Grenoble, France
    Cell Transplant 9:215-21. 2000
  2. ncbi Side-effects of subthalamic stimulation in Parkinson's disease: clinical evolution and predictive factors
    D Guehl
    Service de Neurophysiologie Clinique, Hopital Pellegrin, Place Amelie Rabat Leon, Bordeaux, France
    Eur J Neurol 13:963-71. 2006
  3. ncbi Effect of high-frequency stimulation of the subthalamic nucleus on the neuronal activities of the substantia nigra pars reticulata and ventrolateral nucleus of the thalamus in the rat
    A Benazzouz
    Laboratoire de Neurobiologie Preclinique, INSERM U 318, CHU Pavillon B, BP 217, 38043, Grenoble, France
    Neuroscience 99:289-95. 2000
  4. ncbi Time-course of changes in firing rates and firing patterns of subthalamic nucleus neuronal activity after 6-OHDA-induced dopamine depletion in rats
    Z G Ni
    , INSERM U. 318, CHU - Pavillon B, B.P. 217, 38043 Cedex 09, Grenoble, France
    Brain Res 899:142-7. 2001
  5. ncbi Intrasubthalamic injection of 6-hydroxydopamine induces changes in the firing rate and pattern of subthalamic nucleus neurons in the rat
    Z Ni
    INSERM U.318, Neurobiologie Preclinique, CHU-Pavillon B, BP 217, 38043 Grenoble Cedex 09, France
    Synapse 40:145-53. 2001
  6. ncbi Subthalamic stimulation for Parkinson's disease
    A L Benabid
    Department of Neurosciences, University Hospital of Grenoble, Grenoble, France
    Arch Med Res 31:282-9. 2000
  7. ncbi Unilateral lesion of the nigrostriatal pathway induces an increase of neuronal activity of the pedunculopontine nucleus, which is reversed by the lesion of the subthalamic nucleus in the rat
    S Breit
    INSERM U318, Laboratoire de Neuroscience Preclinique, CHU-Pavillon B, BP 217, 38043 Grenoble Cedex 09, France
    Eur J Neurosci 14:1833-42. 2001
  8. ncbi Ineffective subthalamic nucleus stimulation in levodopa-resistant postischemic parkinsonism
    P Krack
    Department of Clinical and Biological Neurosciences, Joseph Fourier University, Grenoble, France
    Neurology 54:2182-4. 2000
  9. ncbi Deep brain stimulation of the corpus luysi (subthalamic nucleus) and other targets in Parkinson's disease. Extension to new indications such as dystonia and epilepsy
    A L Benabid
    Department of Neurosurgery, CHU A Michallon, Grenoble, France
    J Neurol 248:III37-47. 2001
  10. ncbi Effects of 6-hydroxydopamine-induced severe or partial lesion of the nigrostriatal pathway on the neuronal activity of pallido-subthalamic network in the rat
    S Breit
    INSERM U 318, Department of Preclinical Neurobiology, Joseph Fourier University, Grenoble, France
    Exp Neurol 205:36-47. 2007

Detail Information

Publications11

  1. ncbi Implication of the subthalamic nucleus in the pathophysiology and pathogenesis of Parkinson's disease
    A Benazzouz
    Laboratoire de Neurobiologie Preclinique, INSERM U 318, Grenoble, France
    Cell Transplant 9:215-21. 2000
    ..The evidence reviewed in the present article clearly demonstrates that the STN is implicated in the pathophysiology and pathogenesis of Parkinson's disease...
  2. ncbi Side-effects of subthalamic stimulation in Parkinson's disease: clinical evolution and predictive factors
    D Guehl
    Service de Neurophysiologie Clinique, Hopital Pellegrin, Place Amelie Rabat Leon, Bordeaux, France
    Eur J Neurol 13:963-71. 2006
    ..Age, intensity of axial symptoms and UDPRS II off-medication score before surgery are predictive factors of dysarthria/hypophonia and postural instability after surgery...
  3. ncbi Effect of high-frequency stimulation of the subthalamic nucleus on the neuronal activities of the substantia nigra pars reticulata and ventrolateral nucleus of the thalamus in the rat
    A Benazzouz
    Laboratoire de Neurobiologie Preclinique, INSERM U 318, CHU Pavillon B, BP 217, 38043, Grenoble, France
    Neuroscience 99:289-95. 2000
    ..The reduction in tonic inhibitory drive of nigral neurons induces a disinhibition of activity in the ventrolateral motor thalamic nucleus, which should result in activation of the motor cortical system...
  4. ncbi Time-course of changes in firing rates and firing patterns of subthalamic nucleus neuronal activity after 6-OHDA-induced dopamine depletion in rats
    Z G Ni
    , INSERM U. 318, CHU - Pavillon B, B.P. 217, 38043 Cedex 09, Grenoble, France
    Brain Res 899:142-7. 2001
    ....
  5. ncbi Intrasubthalamic injection of 6-hydroxydopamine induces changes in the firing rate and pattern of subthalamic nucleus neurons in the rat
    Z Ni
    INSERM U.318, Neurobiologie Preclinique, CHU-Pavillon B, BP 217, 38043 Grenoble Cedex 09, France
    Synapse 40:145-53. 2001
    ....
  6. ncbi Subthalamic stimulation for Parkinson's disease
    A L Benabid
    Department of Neurosciences, University Hospital of Grenoble, Grenoble, France
    Arch Med Res 31:282-9. 2000
    ..6, 48.6, and 27%, respectively, when compared with the previous preoperative level. From our experience, HFS of the STN could be considered the surgical therapy of choice at advanced stages of Parkinson's disease...
  7. ncbi Unilateral lesion of the nigrostriatal pathway induces an increase of neuronal activity of the pedunculopontine nucleus, which is reversed by the lesion of the subthalamic nucleus in the rat
    S Breit
    INSERM U318, Laboratoire de Neuroscience Preclinique, CHU-Pavillon B, BP 217, 38043 Grenoble Cedex 09, France
    Eur J Neurosci 14:1833-42. 2001
    ....
  8. ncbi Ineffective subthalamic nucleus stimulation in levodopa-resistant postischemic parkinsonism
    P Krack
    Department of Clinical and Biological Neurosciences, Joseph Fourier University, Grenoble, France
    Neurology 54:2182-4. 2000
    ..This case suggests that parkinsonian patients who do not have a good response to levodopa or in whom a postsynaptic dopaminergic lesion can be shown may not be good candidates for STN surgery...
  9. ncbi Deep brain stimulation of the corpus luysi (subthalamic nucleus) and other targets in Parkinson's disease. Extension to new indications such as dystonia and epilepsy
    A L Benabid
    Department of Neurosurgery, CHU A Michallon, Grenoble, France
    J Neurol 248:III37-47. 2001
    ..It is therefore possible that DBS in STN as well as in other targets could become a potent therapeutic tool in the near future for neurological disorders...
  10. ncbi Effects of 6-hydroxydopamine-induced severe or partial lesion of the nigrostriatal pathway on the neuronal activity of pallido-subthalamic network in the rat
    S Breit
    INSERM U 318, Department of Preclinical Neurobiology, Joseph Fourier University, Grenoble, France
    Exp Neurol 205:36-47. 2007
    ..These data suggest that in the GP-STN-GP network, the excitatory influence of the STN-GP pathway overrides that of the GABAergic GP-STN pathway, questioning the classical model of basal ganglia organization...
  11. ncbi [Deep brain stimulation]
    V Fraix
    Departement de Neurologie, Centre Hospitalier Universitaire de Grenoble, Grenoble
    Rev Neurol (Paris) 160:511-21. 2004
    ..Such studies, including cost benefit studies would be useful to assess the respective value of these different techniques...