Laurent Becquemont

Summary

Country: France

Publications

  1. doi request reprint Evidence for a pharmacogenetic adapted dose of oral anticoagulant in routine medical practice
    Laurent Becquemont
    Pharmacology Department, Faculte de Medecine Paris Sud, Universite Paris Sud, Le Kremlin Bicetre, France
    Eur J Clin Pharmacol 64:953-60. 2008
  2. doi request reprint Influence of CYP3A5 genetic polymorphism on tacrolimus daily dose requirements and acute rejection in renal graft recipients
    Lina Quteineh
    Pharmacology Department, Pierre et Marie Curie University, Saint Antoine University Hospital, Paris, France
    Basic Clin Pharmacol Toxicol 103:546-52. 2008
  3. doi request reprint SLCO1B1 genetic polymorphism influences mycophenolic acid tolerance in renal transplant recipients
    Hugues Michelon
    Pharmacology Department, Univ Paris Sud, Bicetre University Hospital, Le Kremlin, Bicetre, France
    Pharmacogenomics 11:1703-13. 2010
  4. ncbi request reprint Genetic polymorphism of vitamin K epoxide reductase (VKORC1) 1173C>T in a Chinese and a Caucasian population
    Claire Larramendy-Gozalo
    Genetic Molecular, Pharmacogenetic and Hormonology Bicêtre University Hospital, University Paris Sud, Le Kremlin Bicetre, France
    Basic Clin Pharmacol Toxicol 98:611-3. 2006
  5. ncbi request reprint Pharmacogenetics of acenocoumarol pharmacodynamics
    Sandrine Morin
    Pharmacology Department, Saint Antoine University Hospital, Paris, France
    Clin Pharmacol Ther 75:403-14. 2004
  6. doi request reprint Impact of VKORC1 haplotypes on long-term graft function in kidney transplantation
    Lina Quteineh
    Pharmacology Department, Pierre and Marie Curie University, Saint Antoine University Hospital, Paris, France
    Transplantation 86:779-83. 2008
  7. doi request reprint Tacrolimus dose requirement in pediatric liver transplantation: influence of CYP3A5 gene polymorphism
    Philippe Durand
    Pediatric Intensive Care Department, Assistance Publique Hopitaux de Paris, Bicetre Hospital, Le Kremlin Bicetre, France
    Pharmacogenomics 14:1017-25. 2013
  8. ncbi request reprint Environmental and genetic factors associated with morphine response in the postoperative period
    Laurent Coulbault
    Pharmacology Department, Saint Antoine University of Medicine, University Pierre et Marie Curie, Paris, France
    Clin Pharmacol Ther 79:316-24. 2006
  9. doi request reprint Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics
    Laurent Becquemont
    Univ Paris Sud, Faculty of Medicine Paris Sud, Pharmacology Department, Assistance Publique Hopitaux de Paris, Hopital Bicetre, Le Kremlin Bicetre, France
    Pharmacogenomics 12:113-24. 2011
  10. doi request reprint Thyroid-stimulating hormone, 5-HTTLPR genotype, and antidepressant response in depressed women
    Florence Gressier
    Department of Psychiatry, Univ Paris Sud, Assistance Publique Hopitaux de Paris, Bicetre University Hospital, Le Kremlin Bicetre, France
    Psychiatr Genet 21:253-6. 2011

Collaborators

Detail Information

Publications17

  1. doi request reprint Evidence for a pharmacogenetic adapted dose of oral anticoagulant in routine medical practice
    Laurent Becquemont
    Pharmacology Department, Faculte de Medecine Paris Sud, Universite Paris Sud, Le Kremlin Bicetre, France
    Eur J Clin Pharmacol 64:953-60. 2008
    ..Ongoing prospective randomised trials will ascertain definitive answer over the coming years...
  2. doi request reprint Influence of CYP3A5 genetic polymorphism on tacrolimus daily dose requirements and acute rejection in renal graft recipients
    Lina Quteineh
    Pharmacology Department, Pierre et Marie Curie University, Saint Antoine University Hospital, Paris, France
    Basic Clin Pharmacol Toxicol 103:546-52. 2008
    ..Screening for this single nucleotide polymorphism before the transplantation might be helpful for the selection of adequate initial daily dose and to achieve the desired immunosuppression...
  3. doi request reprint SLCO1B1 genetic polymorphism influences mycophenolic acid tolerance in renal transplant recipients
    Hugues Michelon
    Pharmacology Department, Univ Paris Sud, Bicetre University Hospital, Le Kremlin, Bicetre, France
    Pharmacogenomics 11:1703-13. 2010
    ..This study aimed to determine the influence of gene candidates on mycophenolic acid (MPA) response during the first year of renal transplantation...
  4. ncbi request reprint Genetic polymorphism of vitamin K epoxide reductase (VKORC1) 1173C>T in a Chinese and a Caucasian population
    Claire Larramendy-Gozalo
    Genetic Molecular, Pharmacogenetic and Hormonology Bicêtre University Hospital, University Paris Sud, Le Kremlin Bicetre, France
    Basic Clin Pharmacol Toxicol 98:611-3. 2006
  5. ncbi request reprint Pharmacogenetics of acenocoumarol pharmacodynamics
    Sandrine Morin
    Pharmacology Department, Saint Antoine University Hospital, Paris, France
    Clin Pharmacol Ther 75:403-14. 2004
    ..The aim of this study was to investigate the respective contribution of the different cytochrome P450 (CYP) 2C9 genetic polymorphisms to the interindividual variability of acenocoumarol pharmacodynamic response...
  6. doi request reprint Impact of VKORC1 haplotypes on long-term graft function in kidney transplantation
    Lina Quteineh
    Pharmacology Department, Pierre and Marie Curie University, Saint Antoine University Hospital, Paris, France
    Transplantation 86:779-83. 2008
    ..We aimed to study the effect of VKORC1 haplotypes on long-term graft function in a cohort of kidney transplant recipients...
  7. doi request reprint Tacrolimus dose requirement in pediatric liver transplantation: influence of CYP3A5 gene polymorphism
    Philippe Durand
    Pediatric Intensive Care Department, Assistance Publique Hopitaux de Paris, Bicetre Hospital, Le Kremlin Bicetre, France
    Pharmacogenomics 14:1017-25. 2013
    ..Little information is available regarding the influence of CYP3A5 genetic polymorphisms on tacrolimus dose requirement in pediatric liver transplantation...
  8. ncbi request reprint Environmental and genetic factors associated with morphine response in the postoperative period
    Laurent Coulbault
    Pharmacology Department, Saint Antoine University of Medicine, University Pierre et Marie Curie, Paris, France
    Clin Pharmacol Ther 79:316-24. 2006
    ..The aim of this study was to investigate the respective influence of genetic and nongenetic factors on morphine dose requirements and adverse effects after colorectal surgery...
  9. doi request reprint Practical recommendations for pharmacogenomics-based prescription: 2010 ESF-UB Conference on Pharmacogenetics and Pharmacogenomics
    Laurent Becquemont
    Univ Paris Sud, Faculty of Medicine Paris Sud, Pharmacology Department, Assistance Publique Hopitaux de Paris, Hopital Bicetre, Le Kremlin Bicetre, France
    Pharmacogenomics 12:113-24. 2011
    ..We hope that these practical recommendations will help physicians, biologists, scientists and other healthcare professionals to prescribe, perform and interpret these genetic tests...
  10. doi request reprint Thyroid-stimulating hormone, 5-HTTLPR genotype, and antidepressant response in depressed women
    Florence Gressier
    Department of Psychiatry, Univ Paris Sud, Assistance Publique Hopitaux de Paris, Bicetre University Hospital, Le Kremlin Bicetre, France
    Psychiatr Genet 21:253-6. 2011
    ..Further research is needed to understand the underlying mechanism explaining interactions between sex, TSH, and serotonergic function...
  11. doi request reprint Pharmacogenomics of adverse drug reactions: practical applications and perspectives
    Laurent Becquemont
    Universite Paris Sud, Clinical Pharmacology Department, APHP, Hopital Bicetre, 78 rue du General Leclerc, 94275 Le Kremlin Bicetre, France
    Pharmacogenomics 10:961-9. 2009
    ..Parallel development of pharmacogenomic bed tests will certainly establish genetically-based prescriptions in routine medical practice...
  12. doi request reprint The CGGGG insertion/deletion polymorphism of the IRF5 promoter is a strong risk factor for primary Sjögren's syndrome
    Corinne Miceli-Richard
    INSERM U 802, Universite Paris Sud 11, Le Kremlin Bicetre, France
    Arthritis Rheum 60:1991-7. 2009
    ....
  13. ncbi request reprint Absence of association between MDR1 genetic polymorphisms, indinavir pharmacokinetics and response to highly active antiretroviral therapy
    Celine Verstuyft
    Pharmacology Department, Saint Antoine Hospital, Pierre et Marie Curie University, Paris VI, Assistance Publique Hopitaux de Paris, 37 rue de Chaligny 75012 Paris, France
    AIDS 19:2127-31. 2005
    ..The relationship between MDR1 single nucleotide polymorphisms (SNP) and the pharmacokinetic or pharmacodynamic responses to protease inhibitors has been recently challenged...
  14. doi request reprint National observatory on the therapeutic management in ambulatory care patients aged 65 and over, with type 2 diabetes, chronic pain or atrial fibrillation
    Laurent Becquemont
    Pharmacology Department Faculty of Medicine Paris Sud, University Paris Sud Assistance Publique Hôpitaux de Paris, Hopital Bicetre, Le Kremlin Bicetre, France
    Therapie 68:265-83. 2013
    ..Conclusion. The S.AGES cohort presents a unique opportunity to clarify the real-life therapeutic management of ambulatory elderly subjects and will help to identify the factors associated with the occurrence of major clinical events. ..
  15. pmc Impact of genetic factors (VKORC1, CYP2C9, CYP4F2 and EPHX1) on the anticoagulation response to fluindione
    Karine Lacut
    EA 3878, Universite de Bretagne Occidentale, F 29609 Brest, France
    Br J Clin Pharmacol 73:428-36. 2012
    ..The role of these variants in fluindione response is unknown. Our aim was to assess whether genetic factors contribute to the variability in the response to fluindione...
  16. ncbi request reprint Clinical relevance of pharmacogenetics
    Laurent Becquemont
    Pharmacology Department, Bicetre University Hospital, University Paris Sud, Assistance Publique, Hopitaux de Paris, Paris, France
    Drug Metab Rev 35:277-85. 2003
    ..To promote pharmacogenetics in routine medical practice, large prospective randomized trials are needed to demonstrate that pharmacogenetic orientated prescription can sometimes predict drug response without dramatic increase in costs...
  17. ncbi request reprint Frequency of cytochrome P450 2C9 allelic variants in the Chinese and French populations
    Jue Quin Yang
    Pharmacology Department, Saint Antoine University Hospital University Pierre et Marie Curie Assistance Publique Hôpitaux de Paris, Paris, France
    Fundam Clin Pharmacol 17:373-6. 2003
    ..The low frequency of the CYP2C9*2 and CYP2C9*3 allelic variants in Chinese subjects does not justify their detection in clinical practice, unlike French Caucasians...