F Becher

Summary

Country: France

Publications

  1. ncbi request reprint Detection of functional ricin by immunoaffinity and liquid chromatography-tandem mass spectrometry
    F Becher
    CEA, Service de Pharmacologie et d Immunologie, 91191 Gif sur Yvette, France and LCSOB UMR 7613 CNRS, Universite Pierre et Marie Curie, Paris, France
    Anal Chem 79:659-65. 2007
  2. ncbi request reprint Direct determination of phosphorylated intracellular anabolites of stavudine (d4T) by liquid chromatography/tandem mass spectrometry
    A Pruvost
    CEA, Pharmacology and Immunology Unit, DSV/DRM, CEA/Saclay, 91191 Gif-sur-Yvette Cedex, France
    Rapid Commun Mass Spectrom 15:1401-8. 2001
  3. ncbi request reprint Quantification of small therapeutic proteins in plasma by liquid chromatography-tandem mass spectrometry: application to an elastase inhibitor EPI-hNE4
    F Becher
    CEA, Service de Pharmacologie et d Immunologie, 91191 Gif sur Yvette, France
    Anal Chem 78:2306-13. 2006

Collaborators

  • A Pruvost
  • J Grassi
  • C Guerrero
  • J F Delfraissy
  • C Goujard
  • C Creminon
  • H Benech
  • P Bardouille

Detail Information

Publications3

  1. ncbi request reprint Detection of functional ricin by immunoaffinity and liquid chromatography-tandem mass spectrometry
    F Becher
    CEA, Service de Pharmacologie et d Immunologie, 91191 Gif sur Yvette, France and LCSOB UMR 7613 CNRS, Universite Pierre et Marie Curie, Paris, France
    Anal Chem 79:659-65. 2007
    ..1 ng/mL (1.56 pM) after concentration of the toxin from a 500 microL sample size. The variability of the assay was 10%. Finally, the method was applied successfully to milk and tap or bottled water samples...
  2. ncbi request reprint Direct determination of phosphorylated intracellular anabolites of stavudine (d4T) by liquid chromatography/tandem mass spectrometry
    A Pruvost
    CEA, Pharmacology and Immunology Unit, DSV/DRM, CEA/Saclay, 91191 Gif-sur-Yvette Cedex, France
    Rapid Commun Mass Spectrom 15:1401-8. 2001
    ..For the first time, the chain terminator ratio (d4T-TP/dT-TP) could be directly measured. This method can be used simply and routinely on more than 35 samples per day. Extension to other nucleoside analogues is under development...
  3. ncbi request reprint Quantification of small therapeutic proteins in plasma by liquid chromatography-tandem mass spectrometry: application to an elastase inhibitor EPI-hNE4
    F Becher
    CEA, Service de Pharmacologie et d Immunologie, 91191 Gif sur Yvette, France
    Anal Chem 78:2306-13. 2006
    ..Intra- and interassay precision and accuracy were below 15%. No matrix effect was detected...