F Bartolomei

Summary

Country: France

Publications

  1. ncbi request reprint Neural networks underlying epileptic humming
    Fabrice Bartolomei
    Service de Neurophysiologie Clinique et Laboratoire de Neurophysiologie et Neuropsychologie, INSERM EMI 9926, Universite de la Mediterranee, Marseille, France
    Epilepsia 43:1001-12. 2002
  2. doi request reprint The global workspace (GW) theory of consciousness and epilepsy
    Fabrice Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, F 13005, France
    Behav Neurol 24:67-74. 2011
  3. ncbi request reprint Alteration of consciousness in focal epilepsy: the global workspace alteration theory
    Fabrice Bartolomei
    INSERM, U1106, Institut de Neuroscience des Systèmes, Marseille F 13005, France Aix Marseille Université, Faculte de Medecine, Marseille F 13005, France CHU Timone, Service de Neurophysiologie Clinique, Assistance Publique des Hopitaux de Marseille, Marseille F 13005, France Electronic address
    Epilepsy Behav 30:17-23. 2014
  4. doi request reprint Interictal network properties in mesial temporal lobe epilepsy: a graph theoretical study from intracerebral recordings
    F Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille F 13005, France Aix Marseille University, Faculte de Medecine, Marseille F 13005, France CHU Timone, Service de Neurophysiologie Clinique, Assistance Publique des Hopitaux de Marseille, Marseille F 13005, France Electronic address
    Clin Neurophysiol 124:2345-53. 2013
  5. doi request reprint Coherent neural activity and brain synchronization during seizure-induced loss of consciousness
    F Bartolomei
    INSERM, U751, Laboratorie de Neurophysiologie et Neuropsychologie, Marseille, France
    Arch Ital Biol 150:164-71. 2012
  6. doi request reprint Rhinal-hippocampal interactions during déjà vu
    Fabrice Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille F 13005, France
    Clin Neurophysiol 123:489-95. 2012
  7. ncbi request reprint How do brain tumors alter functional connectivity? A magnetoencephalography study
    Fabrice Bartolomei
    Department of Clinical Neurophysiology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Ann Neurol 59:128-38. 2006
  8. doi request reprint Epileptogenicity of brain structures in human temporal lobe epilepsy: a quantified study from intracerebral EEG
    Fabrice Bartolomei
    INSERM, U751, Marseille, F 13000, France
    Brain 131:1818-30. 2008
  9. doi request reprint [The concept of an epileptogenic network in human partial epilepsies]
    F Bartolomei
    INSERM, U751, 13000 Marseille, France
    Neurochirurgie 54:174-84. 2008
  10. ncbi request reprint Acute alteration of emotional behaviour in epileptic seizures is related to transient desynchrony in emotion-regulation networks
    Fabrice Bartolomei
    Service de Neurophysiologie Clinique, INSERM EMI 9926, CHU Timone et Université de la Méditerranée, 264 rue Saint Pierre, 13385 Marseille Cedex 5, France
    Clin Neurophysiol 116:2473-9. 2005

Collaborators

Detail Information

Publications83

  1. ncbi request reprint Neural networks underlying epileptic humming
    Fabrice Bartolomei
    Service de Neurophysiologie Clinique et Laboratoire de Neurophysiologie et Neuropsychologie, INSERM EMI 9926, Universite de la Mediterranee, Marseille, France
    Epilepsia 43:1001-12. 2002
    ..Its study could shed light on the neural networks underlying melodic expression. In this study, we examined the anatomoelectroclinical correlates of humming during epileptic seizures..
  2. doi request reprint The global workspace (GW) theory of consciousness and epilepsy
    Fabrice Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, F 13005, France
    Behav Neurol 24:67-74. 2011
    ..These observations both confirm some predictions of the GW model, and further specify the physiological window of neural coherence (minimum and maximum) associated with conscious processing...
  3. ncbi request reprint Alteration of consciousness in focal epilepsy: the global workspace alteration theory
    Fabrice Bartolomei
    INSERM, U1106, Institut de Neuroscience des Systèmes, Marseille F 13005, France Aix Marseille Université, Faculte de Medecine, Marseille F 13005, France CHU Timone, Service de Neurophysiologie Clinique, Assistance Publique des Hopitaux de Marseille, Marseille F 13005, France Electronic address
    Epilepsy Behav 30:17-23. 2014
    ..This link between abnormal synchrony and AOC offers new perspectives in the treatment of the AOC since means of decreasing consciousness alteration in seizures could improve patients' quality of life...
  4. doi request reprint Interictal network properties in mesial temporal lobe epilepsy: a graph theoretical study from intracerebral recordings
    F Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille F 13005, France Aix Marseille University, Faculte de Medecine, Marseille F 13005, France CHU Timone, Service de Neurophysiologie Clinique, Assistance Publique des Hopitaux de Marseille, Marseille F 13005, France Electronic address
    Clin Neurophysiol 124:2345-53. 2013
    ..Here we investigated the basal properties of epileptogenic networks by applying graph analysis to intracerebral EEG recordings of patients presenting with drug-resistant partial epilepsies during the interictal period...
  5. doi request reprint Coherent neural activity and brain synchronization during seizure-induced loss of consciousness
    F Bartolomei
    INSERM, U751, Laboratorie de Neurophysiologie et Neuropsychologie, Marseille, France
    Arch Ital Biol 150:164-71. 2012
    ....
  6. doi request reprint Rhinal-hippocampal interactions during déjà vu
    Fabrice Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille F 13005, France
    Clin Neurophysiol 123:489-95. 2012
    ..Whether déjà vu results from acute dysfunction of the familiarity system alone (sustained by RC) or from more extensive involvement of the MTL region (including H) is debatable...
  7. ncbi request reprint How do brain tumors alter functional connectivity? A magnetoencephalography study
    Fabrice Bartolomei
    Department of Clinical Neurophysiology, Vrije Universiteit Medical Center, Amsterdam, The Netherlands
    Ann Neurol 59:128-38. 2006
    ..This study was undertaken to test the hypothesis that brain tumors interfere with normal brain function by disrupting functional connectivity of brain networks...
  8. doi request reprint Epileptogenicity of brain structures in human temporal lobe epilepsy: a quantified study from intracerebral EEG
    Fabrice Bartolomei
    INSERM, U751, Marseille, F 13000, France
    Brain 131:1818-30. 2008
    ....
  9. doi request reprint [The concept of an epileptogenic network in human partial epilepsies]
    F Bartolomei
    INSERM, U751, 13000 Marseille, France
    Neurochirurgie 54:174-84. 2008
    ..The emergence of clinical signs in the seizure depend on these phenomena, which in some cases can mimic a normal cognitive process or, on the contrary, lead to a deep rupture in normal cerebral functioning...
  10. ncbi request reprint Acute alteration of emotional behaviour in epileptic seizures is related to transient desynchrony in emotion-regulation networks
    Fabrice Bartolomei
    Service de Neurophysiologie Clinique, INSERM EMI 9926, CHU Timone et Université de la Méditerranée, 264 rue Saint Pierre, 13385 Marseille Cedex 5, France
    Clin Neurophysiol 116:2473-9. 2005
    ..In the present study, we analysed the neurophysiological mechanisms underlying ictal emotional behaviour in 3 patients with frontal lobe epilepsies undergoing intracerebral recordings for presurgical evaluation...
  11. doi request reprint From mesial temporal lobe to temporoperisylvian seizures: a quantified study of temporal lobe seizure networks
    Fabrice Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, France
    Epilepsia 51:2147-58. 2010
    ....
  12. doi request reprint Neural networks underlying parietal lobe seizures: a quantified study from intracerebral recordings
    Fabrice Bartolomei
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, F 13005, France
    Epilepsy Res 93:164-76. 2011
    ..In conclusion, the electrophysiological organization and the clinical manifestations of PLS are various and complex. The subjective manifestations are frequent and often suggestive, therefore must be actively sought...
  13. ncbi request reprint Disturbed functional connectivity in brain tumour patients: evaluation by graph analysis of synchronization matrices
    Fabrice Bartolomei
    Department of Clinical Neurophysiology, VU University Medical Center, Amsterdam, The Netherlands
    Clin Neurophysiol 117:2039-49. 2006
    ..The present work aims at evaluating the impact of brain tumours on spatial patterns of functional connectivity of the brain measured at rest by MEG...
  14. doi request reprint Neural networks underlying hyperkinetic seizures of "temporal lobe" origin
    L Vaugier
    CHU Timone, Service de Neurophysiologie Clinique, Assistance Publique des Hopitaux de Marseille, Marseille, F 13005, France
    Epilepsy Res 86:200-8. 2009
    ..The objective of this study was to determine the features of temporal epilepsy with hyperkinetic seizures and the functional anatomy of involved brain networks...
  15. ncbi request reprint Neural networks involving the medial temporal structures in temporal lobe epilepsy
    F Bartolomei
    Unité d épileptologie et Laboratoire de Neurophysiologie et Neuropsychologie, INSERM EMI 9926, Universite de la Mediterranee, 13385 Marseille Cedex 5, France
    Clin Neurophysiol 112:1746-60. 2001
    ....
  16. ncbi request reprint What is the significance of interictal water diffusion changes in frontal lobe epilepsies?
    M Guye
    INSERM, U 751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, France
    Neuroimage 35:28-37. 2007
    ..396), or surgical outcome (p=0.606). We suggest that SID in normal appearing areas is not a specific signature of epileptogenicity in FLE, and is more likely to reflect multifactorial and potentially evolving neuro-glial injuries...
  17. ncbi request reprint Pre-ictal synchronicity in limbic networks of mesial temporal lobe epilepsy
    F Bartolomei
    Service de Neurophysiologie Clinique, INSERM EMI 9926, CHU Timone et Université de la Méditerranée, 13385 Marseille Cedex 5, France
    Epilepsy Res 61:89-104. 2004
    ..We recorded with intracerebral electrodes the onset of limbic seizures in patients with mesial temporal lobe epilepsy (MTLE) to identify the dynamic interactions between the hippocampus (HIP), amygdala (AMY) and entorhinal cortex (EC)...
  18. ncbi request reprint Cortical stimulation study of the role of rhinal cortex in déjà vu and reminiscence of memories
    F Bartolomei
    Service de Neurophysiologie Clinique, CHU Timone 264 Rue st Pierre, 13005 Marseille, France
    Neurology 63:858-64. 2004
    ..The role of sub-hippocampal structures (EC and PC) in inducing these phenomena has not previously been addressed...
  19. ncbi request reprint [Identification of epileptogenic networks from modeling and nonlinear analysis of SEEG signals]
    F Wendling
    Laboratoire Traitement du Signal et de l Image, INSERM, Universite de Rennes 1, Campus de Beaulieu, Bat 22, 35042 Rennes, France
    Neurophysiol Clin 31:139-51. 2001
    ....
  20. ncbi request reprint Seizures of temporal lobe epilepsy: identification of subtypes by coherence analysis using stereo-electro-encephalography
    F Bartolomei
    INSERM CJF 9706, Faculte de Medecine, and Service d Explorations Fonctionnelles du Système Nerveux, Hopital de la Timone, Marseille, France
    Clin Neurophysiol 110:1741-54. 1999
    ..In this study, we analyzed these interactions using coherence analysis of stereo-encephalographic (SEEG) signals during spontaneous seizures...
  21. ncbi request reprint A method to identify reproducible subsets of co-activated structures during interictal spikes. Application to intracerebral EEG in temporal lobe epilepsy
    J Bourien
    Laboratoire Traitement du Signal et de l Image, INSERM, Universite de Rennes 1, Campus de Beaulieu, Bat 22, 35042 Rennes Cedex, France
    Clin Neurophysiol 116:443-55. 2005
    ....
  22. doi request reprint Indications for network regularization during absence seizures: weighted and unweighted graph theoretical analyses
    S C Ponten
    Department of Clinical Neurophysiology, VU University Medical Center, Amsterdam, The Netherlands
    Exp Neurol 217:197-204. 2009
    ..The network became more regularized in weighted and unweighted analyses, when compared to the more randomized pre-ictal network configuration...
  23. doi request reprint Pitfalls of high-pass filtering for detecting epileptic oscillations: a technical note on "false" ripples
    C G Bénar
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, France
    Clin Neurophysiol 121:301-10. 2010
    ..g., epileptic spikes or artefacts) or signals with harmonics can result in "false" ripples. To illustrate and quantify the occurrence of false ripples on filtered EEG traces...
  24. doi request reprint Performance in recognition memory is correlated with entorhinal/perirhinal interictal metabolism in temporal lobe epilepsy
    E Guedj
    Centre de Resonance Magnetique Biologique et Medicale, UMR CNRS 6612, Marseille, France
    Epilepsy Behav 19:612-7. 2010
    ....
  25. pmc The influence of low-grade glioma on resting state oscillatory brain activity: a magnetoencephalography study
    I Bosma
    Department of Neurology, VU University Medical Center, De Boelelaan 1117, Amsterdam, The Netherlands
    J Neurooncol 88:77-85. 2008
    ..We hypothesized that LGG patients show local as well as diffuse slowing of resting state brain activity compared to healthy controls and that particularly global slowing correlates with neurocognitive dysfunction...
  26. ncbi request reprint 1H-MRS imaging in intractable frontal lobe epilepsies characterized by depth electrode recording
    M Guye
    Service de Neurophysiologie Clinique et Laboratoire de Neurophysiologie et Neuropsychologie, INSERM EMI 9926, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    Neuroimage 26:1174-83. 2005
    ..Our results suggest a link between the relative decrease of N-acetyl-aspartate and the EZ as well as the IZ in FLE. Thus, multilevel (1)H-MRSI protocol may add pertinent information during the non-invasive presurgical evaluation of FLE...
  27. pmc Epileptic fast intracerebral EEG activity: evidence for spatial decorrelation at seizure onset
    F Wendling
    Laboratoire Traitement du Signal et de l Image, INSERM, Universite de Rennes 1, Campus de Beaulieu, Rennes, France
    Brain 126:1449-59. 2003
    ....
  28. doi request reprint [Radiosurgery for drug-resistant epilepsies: state of the art, results and perspectives]
    J Regis
    Service de Neurochirurgie Fonctionnelle et Stereotaxique, Hopital de la Timone, Boulevard Jean Moulin, 13385 Marseille Cedex 5, France
    Neurochirurgie 54:320-31. 2008
    ..There is growing interest in the use of radiosurgery in epilepsy. We analyzed our experience in this field in an attempt to define the potential of radiosurgery in epileptology...
  29. ncbi request reprint Clinical and anatomic characteristics of humming and singing in partial seizures
    F Bartolomei
    Laboratoire de Neurophysiologie et Neuropsychologie, CHU Timone, Marseille, France
    Neurology 69:490-2. 2007
  30. ncbi request reprint The role of gamma knife surgery in the treatment of severe epilepsies
    J Regis
    Stereotactic and Functional Neurosurgery Department, Timone Hospital, Marseille, France
    Epileptic Disord 2:113-22. 2000
    ..Although the benefits of comfort and reduced invasivity can be clearly perceived, larger series and long-term follow up are still required in order to evaluate the future of this particular surgical approach...
  31. ncbi request reprint Epileptic fast activity can be explained by a model of impaired GABAergic dendritic inhibition
    F Wendling
    Laboratoire Traitement du Signal et de l Image, INSERM, Universite de Rennes 1, Campus de Beaulieu, 35042 Rennes Cedex, France
    Eur J Neurosci 15:1499-508. 2002
    ..They show that, in the model, the transition from interictal to fast ictal activity is explained by the impairment of dendritic inhibition...
  32. doi request reprint Long-term efficacy of gamma knife radiosurgery in mesial temporal lobe epilepsy
    F Bartolomei
    Departement de Neurophysiologie Clinique, Assistance Publique Hopitaux de Marseille, Hopital Timone, Marseille, France
    Neurology 70:1658-63. 2008
    ..Gamma knife (GK) radiosurgery has been proposed as an alternative to classic microsurgery in mesial temporal lobe epilepsy (MTLE). Short-term follow-up studies have reported encouraging results, but long-term efficacy is not known...
  33. ncbi request reprint Absence epilepsy with fast rhythmic discharges during sleep: an intermediary form of generalized epilepsy?
    M Guye
    Department of Clinical Neurophysiology, La Timone University Hospital, Marseilles, France
    Epilepsia 42:351-6. 2001
    ..To describe a particular form of absence epilepsy (AE) characterized by an atypical EEG pattern (fast rhythmic discharges) during sleep and an unfavorable course with the persistence of seizures at a late age and drug resistance...
  34. ncbi request reprint Neural network underlying ictal humming demonstrated by very early SPECT: a case report
    Eric Guedj
    Nuclear Medicine Department, INSERM U751, Timone Hospital, Marseille, France
    Epilepsia 47:1968-70. 2006
    ..MRI fusion of the registered ictal and interictal single-photon emission computed tomography (SPECT) substraction exhibited a left neural network involving lateral temporal, inferior frontal, and inferior parietal cortices...
  35. ncbi request reprint [Spatio-temporal dynamics of neuronal networks in partial epilepsy]
    F Bartolomei
    Service de Neurophysiologie Clinique et Epileptologie, INSERM EMI U 9926, CHU Timone et Université de la Méditerranée, Marseille
    Rev Neurol (Paris) 161:767-80. 2005
    ....
  36. doi request reprint Local and remote epileptogenicity in focal cortical dysplasias and neurodevelopmental tumours
    Sandrine Aubert
    Service de Neurophysiologie Clinique, CHU Timone 264 Rue st Pierre, 13005 Marseille, France
    Brain 132:3072-86. 2009
    ..Results suggest that it can help in the delineation of the epileptogenic zone associated with brain lesions and that it could be used in the definition of the subsequent surgical resection...
  37. ncbi request reprint Semiologic and electrophysiologic correlations in temporal lobe seizure subtypes
    Louis Maillard
    Service de Neurophysiologie Clinique, Hopital de la Timone, Inserm EMI 99 26, Universite de la Mediterranee, Marseille, France
    Epilepsia 45:1590-9. 2004
    ..The purpose of the study was therefore to study the correlations of ictal semiology with the spatiotemporal pattern of discharge in temporal lobe seizures...
  38. ncbi request reprint Small-world networks and epilepsy: graph theoretical analysis of intracerebrally recorded mesial temporal lobe seizures
    S C Ponten
    Department of Clinical Neurophysiology, VU University Medical Centre, 1007 MB Amsterdam, The Netherlands
    Clin Neurophysiol 118:918-27. 2007
    ..We tested the hypothesis that real functional brain networks during seizures display small-world features, using intracerebral recordings of mesial temporal lobe seizures...
  39. ncbi request reprint Mining reproducible activation patterns in epileptic intracerebral EEG signals: application to interictal activity
    Jérôme Bourien
    Laboratoire Traitement du Signal et de l Image, INSERM, Universite de Rennes 1, Campus de Beaulieu, 35042 Rennes Cedex, France
    IEEE Trans Biomed Eng 51:304-15. 2004
    ..Results show that the methodology allows reproducible sequential activation sets to be identified from signals recorded in four patients. Potential advantages of the method are discussed with respect to other approaches...
  40. ncbi request reprint Metabolic and electrophysiological alterations in subtypes of temporal lobe epilepsy: a combined proton magnetic resonance spectroscopic imaging and depth electrodes study
    Maxime Guye
    Service de Neurophysiologie Clinique and Laboratoire de Neurophysiologie et Neuropsychologie, EMI U INSERM 9926, Marseille, France
    Epilepsia 43:1197-209. 2002
    ....
  41. ncbi request reprint Impaired consciousness during temporal lobe seizures is related to increased long-distance cortical-subcortical synchronization
    Marie Arthuis
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, F 13005, France
    Brain 132:2091-101. 2009
    ..We suggest that excessive synchronization overloads the structures involved in consciousness processing, preventing them from treating incoming information, thus resulting in LOC...
  42. ncbi request reprint [The presurgical evaluation of epilepsies]
    F Bartolomei
    Service de Neurophysiologie Clinique Unité d Epileptologie, INSERM 9926 CHU Timone, Marseille, France
    Rev Neurol (Paris) 158:4S55-64. 2002
    ..Finally, the surgical procedure must be adapted according to the distribution and dynamics of the anatomical and functional abnormalities which individually define each case of epilepsy...
  43. ncbi request reprint What role for radiosurgery in mesial temporal lobe epilepsy
    J Regis
    Service de Neurochirurgie Fonctionnelle et Stereotaxique, La Timone, Marseille, France
    Zentralbl Neurochir 63:101-5. 2002
    ..However, a larger number of treated patients and a more prolonged follow-up remains necessary to assess this approach in a more definitive way...
  44. ncbi request reprint Is it juvenile myoclonic epilepsy?
    P Gelisse
    Centre Saint Paul, Marseille, France
    Epileptic Disord 2:27-32. 2000
    ..In our opinion, JME can be diagnosed in very uncommon settings, including patients with significant brain damage, as long as all the other criteria for the diagnosis are present...
  45. ncbi request reprint Radiosurgery for trigeminal neuralgia and epilepsy
    J Regis
    Stereotactic and Functional Neurosurgery Department, Neurophysiology and Neuropsychology INSERM CJF 9706, Timone Hospital, Marseilles, France
    Neurosurg Clin N Am 10:359-77. 1999
    ..After additional follow-up to demonstrate the absence of long-term consequences, this fascinating new approach could change epilepsy surgery practice dramatically...
  46. ncbi request reprint Gamma knife surgery for mesial temporal lobe epilepsy
    J Regis
    Stereotactic and Functional Neurosurgery Department, Neurophysiology Neuropsychology INSERM, Timone Hospital, Marseilles France
    J Neurosurg 93:141-6. 2000
    ..These results prompted the authors to investigate the use of radiosurgery as a new way of treating epilepsy not associated with space-occupying lesions...
  47. ncbi request reprint Gamma knife surgery for epilepsy related to hypothalamic hamartomas
    J Regis
    Department of Stereotactic and Functional Neurosurgery, La Timone Hospital, Marseilles, France
    Neurosurgery 47:1343-51; discussion 1351-2. 2000
    ..Morbidity and mortality rates for microsurgery in this area are significant. Gamma knife surgery (GKS) is less invasive and seems to be well adapted for this indication...
  48. ncbi request reprint Radiosurgery for epilepsy associated with cavernous malformation: retrospective study in 49 patients
    J Regis
    Department of Stereotactic Neurosurgery, Timone Hospital, Marseilles, France
    Neurosurgery 47:1091-7. 2000
    ..To explore the potential alternative role of radiosurgery and to evaluate its safety and efficacy for this indication, we conducted a retrospective multicenter study...
  49. doi request reprint [Isolated autobiographical amnesia: a neurological basis?]
    O Felician
    Service de Neurologie et de Neuropsychologie, CHU de la Timone, AP HM, 264, rue Saint Pierre 13385 Marseille cedex 5, France
    Rev Neurol (Paris) 165:449-59. 2009
    ..This study aims at characterizing this poorly documented clinical syndrome and at discussing its potential pathophysiological basis...
  50. ncbi request reprint Gamma knife surgery for epilepsy related to hypothalamic hamartomas
    J Regis
    Stereotactic and Functional Neurosurgery Department, Timone Hospital, Marseilles, France
    Acta Neurochir Suppl 91:33-50. 2004
    ..A first retrospective study has shown a very good safety and efficacy level but for a more reliable evaluation a prospective study would be required...
  51. ncbi request reprint Gamma knife surgery for mesial temporal lobe epilepsy
    J Regis
    Stereotactic and Functional Neurosurgery Department, Timone Hospital, Orsay, France
    Epilepsia 40:1551-6. 1999
    ..Results prompted the idea to test radiosurgery as a new way of treating epilepsy without space-occupying lesions...
  52. doi request reprint From EEG signals to brain connectivity: a model-based evaluation of interdependence measures
    Fabrice Wendling
    INSERM, U642, Rennes, F 35000, France
    J Neurosci Methods 183:9-18. 2009
    ..In addition, time-frequency methods are also recommended when coupling in specific frequency sub-bands ("frequency-locking") is likely to occur as in epilepsy...
  53. doi request reprint Graph theoretical analysis of structural and functional connectivity MRI in normal and pathological brain networks
    Maxime Guye
    Centre de Resonance Magnetique Biologique et Medicale, UMR CNRS 6612, Faculte de Medecine, 27 Boulevard Jean Moulin, 13385, Marseille Cedex 05, France
    MAGMA 23:409-21. 2010
    ..Graph theoretical analysis of connectivity MRI data provides an outstanding framework to merge anatomical and functional data in order to better understand brain pathologies...
  54. ncbi request reprint Déjà-vu in temporal lobe epilepsy: metabolic pattern of cortical involvement in patients with normal brain MRI
    Eric Guedj
    Service Central de Biophysique et Médecine Nucléaire, CHU Timone and Centre Européen de Recherche en Imagerie Médicale, CERIMED and Centre d Investigation Clinique, CIC, INSERM, Universite de la Mediterranee, Marseille F 13000, France
    Neuropsychologia 48:2174-81. 2010
    ....
  55. doi request reprint Long-term consolidation of declarative memory: insight from temporal lobe epilepsy
    Eve Tramoni
    Laboratoire Epilepsies et Cognition, INSERM U 751, Universite de la Mediterranee, Faculté de médecine La Timone, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France
    Brain 134:816-31. 2011
    ..They suggest that mild medial temporal lobe dysfunction can impede the building and stabilization of episodic memories but leaves long-term semantic and single-items mnemonic traces intact...
  56. ncbi request reprint Gamma knife surgery in mesial temporal lobe epilepsy: a prospective multicenter study
    Jean Regis
    Stereotactic and Functional Neurosurgery Department, Timone Hospital, Marseille APM, France
    Epilepsia 45:504-15. 2004
    ..This article is the first prospective documentation of the efficacy and safety of gamma knife surgery (GKS) in the treatment of drug-resistant epilepsies of mesial temporal lobe origin...
  57. doi request reprint Reading epilepsy from the dominant temporo-occipital region
    Martine Gavaret
    Assistance Publique Hôpitauxde Marseille, Hopital de la Timone, 264 rue Saint Pierre, Marseille 13005, France
    J Neurol Neurosurg Psychiatry 81:710-5. 2010
    ..However, distinct ictal features including visual symptoms and paroxysmal a- or dyslexia are described in some patients. The anatomical substrate of ictogenesis in reading epilepsy remains poorly understood...
  58. pmc Spatial analysis of intracerebral electroencephalographic signals in the time and frequency domain: identification of epileptogenic networks in partial epilepsy
    Fabrice Wendling
    INSERM, U642, Rennes 35000, France
    Philos Trans A Math Phys Eng Sci 367:297-316. 2009
    ..Most of these methods were developed by our group and are routinely used during pre-surgical evaluation. Examples are detailed. Results, as well as limitations of the methods, are also discussed...
  59. ncbi request reprint Gamma knife surgery for epilepsy related to hypothalamic hamartomas
    Jean Regis
    Department of Functional Neurosurgery, INSERM 751, Timone Hospital, Marseilles, France
    Semin Pediatr Neurol 14:73-9. 2007
    ..The disadvantage of radiosurgery is its delayed action. Longer follow-up is mandatory for a reliable evaluation of the role of GKS...
  60. doi request reprint Source localization of scalp-EEG interictal spikes in posterior cortex epilepsies investigated by HR-EEG and SEEG
    Martine Gavaret
    Inserm UMR 751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, France
    Epilepsia 50:276-89. 2009
    ..To determine the validity of scalp-electroencephalography (EEG)-interictal spike (IIS) source localization in posterior cortex epilepsies (PCE)...
  61. doi request reprint Decreased basal fMRI functional connectivity in epileptogenic networks and contralateral compensatory mechanisms
    Gaelle Bettus
    Centre de Resonance Magnetique Biologique et Medicale, UMR CNRS 6612, Faculte de Medecine, 27 Boulevard Jean Moulin, Marseille, France
    Hum Brain Mapp 30:1580-91. 2009
    ..This is the first demonstration of decreased basal functional connectivity within epileptogenic networks with concomitant contralateral increased connectivity possibly reflecting compensatory mechanisms...
  62. doi request reprint Imaging structural and functional connectivity: towards a unified definition of human brain organization?
    Maxime Guye
    Centre de Resonance Magnetique Biologique et Medicale UMR CNRS 6612, France
    Curr Opin Neurol 21:393-403. 2008
    ..We will also emphasize the benefits provided by computational models of complex networks such as graph theory...
  63. doi request reprint Enhanced EEG functional connectivity in mesial temporal lobe epilepsy
    Gaelle Bettus
    INSERM, U751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, France
    Epilepsy Res 81:58-68. 2008
    ....
  64. ncbi request reprint The role of corticothalamic coupling in human temporal lobe epilepsy
    Maxime Guye
    Service de Neurophysiologie Clinique, Unité Epilepsy and Cognition INSERM U751, CHU Timone et Université de la Méditerranée, Marseille, France
    Brain 129:1917-28. 2006
    ....
  65. ncbi request reprint Epilepsy related to hypothalamic hamartomas: surgical management with special reference to gamma knife surgery
    Jean Regis
    Functional Neurosurgery Department, INSERM 751, Timone Hospital, Marseille, France
    Childs Nerv Syst 22:881-95. 2006
    ..The aim of this report is to point on some clinical and anatomical parameters supposed to influence the choice of the surgical approach and to emphasize the specific role of radiosurgery...
  66. ncbi request reprint Stereoelectroencephalography in presurgical assessment of MRI-negative epilepsy
    Aileen McGonigal
    INSERM, U 751, Laboratoire de Neurophysiologie et Neuropsychologie, Marseille, F 13000, France
    Brain 130:3169-83. 2007
    ..05). Of MRI-negative cases that underwent surgery, 10/23 (43%) had focal cortical dysplasia. This series showed that SEEG was equally effective in the presurgical evaluation of MRI-negative and lesional epilepsies...
  67. doi request reprint Role of resting state functional connectivity MRI in presurgical investigation of mesial temporal lobe epilepsy
    Gaelle Bettus
    Centre de Résonance Magnétique Biologique et Médicale CRMBM, Marseille, France
    J Neurol Neurosurg Psychiatry 81:1147-54. 2010
    ..The authors aimed to determine the ability of resting-state functional connectivity MRI (fcMRI) to lateralise/localise the epileptogenic zone in patients presenting with mesial temporal lobe epilepsy (MTLE) at the individual level...
  68. ncbi request reprint Functional interactions in brain networks underlying epileptic seizures in bilateral diffuse periventricular heterotopia
    Luc Valton
    CHU Timone, Service de Neurophysiologie Clinique, 264 rue St Pierre, 13005 Marseille, France
    Clin Neurophysiol 119:212-23. 2008
    ..Our aim was to investigate relationships between heterotopic and remote cortical structures at seizure initiation, in a patient with bilateral periventricular nodular heterotopias (BPNH) explored by intracerebral electrodes...
  69. doi request reprint Source localization of ictal epileptic activity investigated by high resolution EEG and validated by SEEG
    Laurent Koessler
    INSERM, UMR751, Marseille, F 13000, France
    Neuroimage 51:642-53. 2010
    ....
  70. ncbi request reprint Electric source imaging in frontal lobe epilepsy
    Martine Gavaret
    Laboratoire de Neurophysiologie et Neuropsychologie, INSERM U751, Faculte de Medecine, Marseille, France
    J Clin Neurophysiol 23:358-70. 2006
    ....
  71. ncbi request reprint Electric source imaging in temporal lobe epilepsy
    Martine Gavaret
    Laboratoire de Neurophysiologie et Neuropsychologie, INSERM E 9926, Faculte de Medecine, Marseille, France
    J Clin Neurophysiol 21:267-82. 2004
    ..In TLE with a mediolateral or a lateral interictal distribution, only the lateral component is detectable on surface EEG and accurately localizable by source localization tools...
  72. ncbi request reprint Entorhinal cortex involvement in human mesial temporal lobe epilepsy: an electrophysiologic and volumetric study
    Fabrice Bartolomei
    Service de Neurophysiologie Clinique et Epileptologie and INSERM EMI 9926 CHU TIMONE et Université de la Méditerranée, Marseille, France
    Epilepsia 46:677-87. 2005
    ..The purpose of the study was to determine whether atrophy of the EC evaluated by the quantitative magnetic resonance imaging (MRI) method is correlated with the epileptogenicity of this structure in TLE...
  73. doi request reprint Computational modeling of high-frequency oscillations at the onset of neocortical partial seizures: from 'altered structure' to 'dysfunction'
    Behnam Molaee-Ardekani
    INSERM, U642, Universite de Rennes 1, LTSI, Rennes, F 35000, France
    Neuroimage 52:1109-22. 2010
    ..They also provide insights into potentially important mechanisms for high-frequency epileptic activity generation...
  74. pmc Synchronized brain activity and neurocognitive function in patients with low-grade glioma: a magnetoencephalography study
    Ingeborg Bosma
    Department of Neurology, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Neuro Oncol 10:734-44. 2008
    ....
  75. doi request reprint MRI-negative prefrontal epilepsy due to cortical dysplasia explored by stereoelectroencephalography (SEEG)
    Aileen McGonigal
    INSERM, U 751, Laboratoire de Neurophysiologie et Neuropsychologie, France
    Epileptic Disord 10:330-8. 2008
    ..There was no visible lesion on MRI, but following localisation using stereoelectroencephalography (SEEG), surgery revealed an underlying dysplastic lesion...
  76. pmc Interictal to ictal transition in human temporal lobe epilepsy: insights from a computational model of intracerebral EEG
    Fabrice Wendling
    Laboratoire Traitement du Signal et de l Image, INSERM Université de Rennes 1, Campus de Beaulieu, Rennes Cedex, France
    J Clin Neurophysiol 22:343-56. 2005
    ..These findings obtained from model identification in human temporal lobe epilepsy are in agreement with some results obtained experimentally, either on animal models of epilepsy or on the human epileptic tissue...
  77. pmc Time-frequency characterization of interdependencies in nonstationary signals: application to epileptic EEG
    Karim Ansari-Asl
    Laboratoire Traitement du Signal et de l Image, INERM U 642, Universite de Rennes 1, Campus de Beaulieu, 35042 Rennes, France
    IEEE Trans Biomed Eng 52:1218-26. 2005
    ..Finally, we illustrate the importance of characterizing the relationship in both time and frequency domains by comparing with frequency-independent methods (linear and nonlinear)...
  78. ncbi request reprint Emotion induction after direct intracerebral stimulations of human amygdala
    Laura Lanteaume
    Laboratoire Parole et Langage, CNRS et Université de Provence UMR 6054, 13621 Aix en Provence, Cedex 1, France
    Cereb Cortex 17:1307-13. 2007
    ..These findings provide direct in vivo evidence that the human amygdala is involved in emotional experiences and strengthen the hypothesis of a functional asymmetry of the amygdala for valence and arousal processing...
  79. ncbi request reprint Recollection of vivid memories after perirhinal region stimulations: synchronization in the theta range of spatially distributed brain areas
    Emmanuel Barbeau
    Laboratoire de Neurophysiologie et de Neuropsychologie, INSERM EMI U 9926, Faculte de Medecine, 27 Boulevard Jean Moulin, 13385 Marseille, France
    Neuropsychologia 43:1329-37. 2005
    ..Experiential phenomena are rarely obtained after brain stimulation. Replication of these results is thus required due to the small number of observations reported...
  80. ncbi request reprint Epileptogenesis due to peripheral injury as a cause of focal epilepsy
    Allison E Spiller
    Department of Medicine, Division of Neurology, Kingston General Hospital, Queen s University, Kingston, Canada
    Epilepsia 46:1252-5. 2005
    ..To report three patients in whom focal epilepsy developed shortly after painful soft tissue injuries to their hands...
  81. ncbi request reprint [Three dimensional stereotactic functional neurosurgical planning]
    Taku Ochiai
    Department of Neurosurgery, Neurological Institute, Tokyo Women s Medical University
    Nihon Rinsho 62:669-76. 2004
    ..Three-dimensional anatomical target provides us the best treatment for stereotactic neurosurgery...
  82. ncbi request reprint Large-scale expression study of human mesial temporal lobe epilepsy: evidence for dysregulation of the neurotransmission and complement systems in the entorhinal cortex
    Sarah Jamali
    INSERM UMR 491, Universite de la Mediterranee, France
    Brain 129:625-41. 2006
    ..Altered expression of NPY1R and C3 was also demonstrated at the protein level. Overall, our data indicate that local dysregulation of the neurotransmission and complement systems in the EC is a frequent event in human MTLE...