F Barbut

Summary

Country: France

Publications

  1. ncbi Reducing the spread of Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus on a burns unit through the intervention of an infection control bundle
    Frederic Barbut
    Saint Antoine Hospital, Paris, France
    Burns 39:395-403. 2013
  2. ncbi New molecular methods for the diagnosis of Clostridium difficile infections
    F Barbut
    National Reference Laboratory for Clostridium difficile, Groupe de recherche clinique N 2 EPIDIFF, Université Pierre et Marie Curie Paris VI Service de Microbiologie, Hopital Saint Antoine, Assistance Publique Hôpitaix de Paris, Paris, France
    Drugs Today (Barc) 48:673-84. 2012
  3. ncbi Activity in vitro of hydrogen peroxide vapour against Clostridium difficile spores
    F Barbut
    National Reference Laboratory for Clostridium difficile, Hopital Saint Antoine, Paris, France
    J Hosp Infect 80:85-7. 2012
  4. ncbi Epidemiology and control of Clostridium difficile infections in healthcare settings: an update
    Frederic Barbut
    National Reference Laboratory for Clostridium difficile, Pierre et Marie Curie University, Hopital Saint Antoine, UHLIN, site Saint Antoine, Paris, France
    Curr Opin Infect Dis 24:370-6. 2011
  5. ncbi Rapid diagnosis of Clostridium difficile infection by multiplex real-time PCR
    F Barbut
    National Reference Laboratory for C difficile, Paris VI University, Paris, France
    Eur J Clin Microbiol Infect Dis 30:1279-85. 2011
  6. ncbi Comparison of the efficacy of a hydrogen peroxide dry-mist disinfection system and sodium hypochlorite solution for eradication of Clostridium difficile spores
    F Barbut
    National Reference Laboratory for Clostridium difficile, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Paris
    Infect Control Hosp Epidemiol 30:507-14. 2009
  7. ncbi Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates
    F Barbut
    Microbiology Unit, Hopital Saint Antoine, Paris, France
    Clin Microbiol Infect 13:1048-57. 2007
  8. ncbi Development of a new PCR-ribotyping method for Clostridium difficile based on ribosomal RNA gene sequencing
    P Bidet
    Laboratoire de Bacteriologie, Centre Hospitalo Universitaire Saint Antoine, Assistance Publique Hopitaux de Paris, France
    FEMS Microbiol Lett 175:261-6. 1999
  9. ncbi Antimicrobial susceptibilities and serogroups of clinical strains of Clostridium difficile isolated in France in 1991 and 1997
    F Barbut
    Department of Microbiology, Centre Hospitalier Universitaire Saint Antoine, Assistance Publique Hopitaux de Paris, Universite Paris VI, Paris 12, France
    Antimicrob Agents Chemother 43:2607-11. 1999
  10. ncbi A European survey of diagnostic methods and testing protocols for Clostridium difficile
    F Barbut
    Laboratory of Microbiology, Center Hospitalier Universitaire Saint-Antoine, , Paris, France
    Clin Microbiol Infect 9:989-96. 2003

Detail Information

Publications31

  1. ncbi Reducing the spread of Acinetobacter baumannii and methicillin-resistant Staphylococcus aureus on a burns unit through the intervention of an infection control bundle
    Frederic Barbut
    Saint Antoine Hospital, Paris, France
    Burns 39:395-403. 2013
    ..The infection control bundle resulted in a significant reduction in the incidence of nosocomial MRSA and A. baumannii in our burns unit and prevented further outbreaks of these organisms...
  2. ncbi New molecular methods for the diagnosis of Clostridium difficile infections
    F Barbut
    National Reference Laboratory for Clostridium difficile, Groupe de recherche clinique N 2 EPIDIFF, Université Pierre et Marie Curie Paris VI Service de Microbiologie, Hopital Saint Antoine, Assistance Publique Hôpitaix de Paris, Paris, France
    Drugs Today (Barc) 48:673-84. 2012
    ..In particular, these tests again raise the crucial question of the clinical significance of the presence of a toxigenic strain without any free toxin in stools...
  3. ncbi Activity in vitro of hydrogen peroxide vapour against Clostridium difficile spores
    F Barbut
    National Reference Laboratory for Clostridium difficile, Hopital Saint Antoine, Paris, France
    J Hosp Infect 80:85-7. 2012
    ..C. difficile was completely eradicated from the exposed carriers regardless of the C. difficile strain or surface used. HPV can be considered for the eradication of C. difficile spores from the hospital environment...
  4. ncbi Epidemiology and control of Clostridium difficile infections in healthcare settings: an update
    Frederic Barbut
    National Reference Laboratory for Clostridium difficile, Pierre et Marie Curie University, Hopital Saint Antoine, UHLIN, site Saint Antoine, Paris, France
    Curr Opin Infect Dis 24:370-6. 2011
    ..The objectives of this review are to highlight the recent epidemiological data and to provide an overview of the current knowledge of infection control measures...
  5. ncbi Rapid diagnosis of Clostridium difficile infection by multiplex real-time PCR
    F Barbut
    National Reference Laboratory for C difficile, Paris VI University, Paris, France
    Eur J Clin Microbiol Infect Dis 30:1279-85. 2011
    ..59%, 97.43%, 78.02%, and 98.57%, respectively, for the real-time PCR and 70.73%, 100%, 100%, and 97.08%, respectively, for the cytotoxicity assay...
  6. ncbi Comparison of the efficacy of a hydrogen peroxide dry-mist disinfection system and sodium hypochlorite solution for eradication of Clostridium difficile spores
    F Barbut
    National Reference Laboratory for Clostridium difficile, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Paris
    Infect Control Hosp Epidemiol 30:507-14. 2009
    ..To compare a hydrogen peroxide dry-mist system and a 0.5% hypochlorite solution with respect to their ability to disinfect Clostridium difficile-contaminated surfaces in vitro and in situ...
  7. ncbi Prospective study of Clostridium difficile infections in Europe with phenotypic and genotypic characterisation of the isolates
    F Barbut
    Microbiology Unit, Hopital Saint Antoine, Paris, France
    Clin Microbiol Infect 13:1048-57. 2007
    ..Ongoing epidemiological surveillance of cases of CDAD, with periodic characterisation of the strains involved, is required to detect clustering of cases in time and space and to monitor the emergence of specific highly virulent clones...
  8. ncbi Development of a new PCR-ribotyping method for Clostridium difficile based on ribosomal RNA gene sequencing
    P Bidet
    Laboratoire de Bacteriologie, Centre Hospitalo Universitaire Saint Antoine, Assistance Publique Hopitaux de Paris, France
    FEMS Microbiol Lett 175:261-6. 1999
    ..This typing method has evidenced major qualities such as easiness, rapidity and reproducibility. However, its discriminatory power has to be evaluated to validate its importance as a typing tool for C. difficile...
  9. ncbi Antimicrobial susceptibilities and serogroups of clinical strains of Clostridium difficile isolated in France in 1991 and 1997
    F Barbut
    Department of Microbiology, Centre Hospitalier Universitaire Saint Antoine, Assistance Publique Hopitaux de Paris, Universite Paris VI, Paris 12, France
    Antimicrob Agents Chemother 43:2607-11. 1999
    ..Periodic studies are needed in order to detect changes in serogroups and the emergence of strains with decreased susceptibility to therapeutic drugs...
  10. ncbi A European survey of diagnostic methods and testing protocols for Clostridium difficile
    F Barbut
    Laboratory of Microbiology, Center Hospitalier Universitaire Saint-Antoine, , Paris, France
    Clin Microbiol Infect 9:989-96. 2003
    ..difficile. Precise guidelines for C. difficile diagnosis would be the first step to make possible accurate comparison of the incidence and the epidemiology of CDAD from one hospital to another or from one country to another...
  11. ncbi Usefulness of simultaneous detection of toxin A and glutamate dehydrogenase for the diagnosis of Clostridium difficile-associated diseases
    F Barbut
    Service de Bacteriologie Virologie, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, France
    Eur J Clin Microbiol Infect Dis 19:481-4. 2000
    ..6%). Triage is a very rapid (20 min) and easy-to-perform test. It could be useful for diagnostic purposes and also for detecting nontoxigenic strains in epidemiogical studies...
  12. ncbi Comparison of PCR-ribotyping, arbitrarily primed PCR, and pulsed-field gel electrophoresis for typing Clostridium difficile
    P Bidet
    Laboratoire de Bacteriologie, Hopital Saint Antoine, Centre Hospitalo Universitaire Saint Antoine, Universite Paris 6, Assistance Publique Hopitaux de Paris, Paris, France
    J Clin Microbiol 38:2484-7. 2000
    ..We conclude that PCR-ribotyping offers the best combination of advantages as an initial typing tool for C. difficile...
  13. ncbi Epidemiology of recurrences or reinfections of Clostridium difficile-associated diarrhea
    F Barbut
    Department of Microbiology, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Paris, France
    J Clin Microbiol 38:2386-8. 2000
    ..The results showed that 48.4% of clinical recurrences were, in fact, reinfections with a different strain of C. difficile. Rates of clinical recurrences could therefore be reduced by implementing strict isolation precautions...
  14. ncbi [Epidemiology, risk factors and prevention of Clostridium difficile nosocomial infections]
    F Barbut
    Unité d hygiène et de lutte contre les infections nosocomiales UHLNIN, Hopital Saint Antoine, 184, rue du Faubourg Saint Antoine, 75571 Paris, 12, France
    Pathol Biol (Paris) 48:745-55. 2000
    ..C. difficile is a common cause of infectious diarrhea and should be therefore systematically investigated in patients with nosocomial diarrhea...
  15. ncbi Comparison of a commercially available repetitive-element PCR system (DiversiLab) with PCR ribotyping for typing of clostridium difficile strains
    C Eckert
    ER8, Universite Pierre et Marie Curie, Paris, France
    J Clin Microbiol 49:3352-4. 2011
    ..rep-PCR showed a higher discriminatory power than PCR ribotyping. Nevertheless, this method requires technical skill, and visual interpretation of rep-PCR fingerprint patterns may be difficult...
  16. ncbi [Role of the microbiology laboratory in the diagnosis of nosocomial diarrhea]
    D Decre
    Service de Microbiologie, Hopital Saint Antoine, 184 rue du Faubourg Saint Antoine, 75571 Paris, 12, France
    Pathol Biol (Paris) 48:733-44. 2000
    ..Various typing methods have been developed and may be routinely used in epidemiological investigations...
  17. ncbi Epidemiology of Clostridium difficile-associated infections
    F Barbut
    Research Group on Clostridium difficile, Center Hospitalo-Universitaire Saint-Antoine, , , Paris, France
    Clin Microbiol Infect 7:405-10. 2001
    ..C. difficile is a common cause of infectious diarrhea and should be therefore systematically investigated in patients with nosocomial diarrhea...
  18. ncbi Antibiotic-associated diarrhoea and Clostridium difficile in the community
    L Beaugerie
    Department of Gastroenterology, Saint Antoine Medical Faculty, Université Paris VI and Assistance Publique Hôpitaux de Paris, Paris, France
    Aliment Pharmacol Ther 17:905-12. 2003
    ..The involvement of C. difficile infection in antibiotic-associated diarrhoea in the community is poorly documented...
  19. ncbi [Totally implantable venous access ports: frequency of complications and analysis of bacterial contamination after ablation]
    F Barbut
    Unite d Hygiene et de Lutte contre les Infections Nosocomiales, Hopital Saint Antoine, 184, rue du Faubourg Saint Antoine, 75012 Paris, France
    Pathol Biol (Paris) 52:566-74. 2004
    ..Implantation and use of these devices are each associated with infectious or mechanical complications...
  20. ncbi Comparative value of colonic biopsy and intraluminal fluid culture for diagnosis of bacterial acute colitis in immunocompetent patients. Infectious Colitis Study Group
    F Barbut
    Department of Microbiology, Hopital Saint Antoine, Paris, France
    Clin Infect Dis 29:356-60. 1999
    ..Culture of biopsy specimens adds little to the diagnosis of infectious colitis, and stools and intraluminal fluids appear to have comparable value...
  21. ncbi Outbreak of Clostridium difficile-related diarrhoea in an adult oncology unit: risk factors and microbiological characteristics
    E Blot
    Department of Microbiology, Saint Antoine Hospital, Paris, France
    J Hosp Infect 53:187-92. 2003
    ..Serotyping and genotyping showed that several strains were involved in this outbreak, with only two instances of patient-to-patient transmission, involving four and two patients...
  22. ncbi Nosocomial infections and hospital mortality: a multicentre epidemiology study
    B Kaoutar
    Regional Center for Nosocomial Infection Control, Paris, France
    J Hosp Infect 58:268-75. 2004
    ..To improve healthcare quality, further studies are needed to elucidate the processes that may contribute to fatal severe NI...
  23. ncbi Curbing methicillin-resistant Staphylococcus aureus in 38 French hospitals through a 15-year institutional control program
    Vincent Jarlier
    Université Pierre et Marie Curie Hôpital Pitié Salpêtrière, Assistance Publique Hopitaux de Paris, France
    Arch Intern Med 170:552-9. 2010
    ..In the late 1980s, the proportion of methicillin resistance among clinical strains of Staphylococcus aureus (MRSA) reached approximately 40% at AP-HP...
  24. ncbi A monthly systematic bacteriological report improves accuracy of identification of hospital-acquired infections in an ICU
    J-L Baudel
    , , Assistance Publique, , 184 rue du Faubourg Saint Antoine, 75 571 Paris Cedex 12, France
    J Hosp Infect 53:14-7. 2003
    ..We conclude that the routine HAI surveillance programme is reliable, except for the last 48 h in the ICU. The monthly bacteriological report improved the accuracy of the HAI reporting rate...
  25. ncbi Fluoroquinolone resistance in Clostridium difficile isolates from a prospective study of C. difficile infections in Europe
    Patrizia Spigaglia
    1Department of Infectious, Parasitic and Immune Mediated Diseases, Istituto Superiore di Sanita, Rome, Italy
    J Med Microbiol 57:784-9. 2008
    ....
  26. ncbi [Update on Clostridium difficile infections]
    K Blanckaert
    Centre de coordination de la lutte contre les infections nosocomicales Paris Nord, 15, rue de l Ecole de Medecine, 75006 Paris, France
    Rev Med Interne 29:209-14. 2008
    ..FUTURE PROSPECTS AND PROJECTS: A systematic reporting of C. difficile incidence by health facilities should enable a better assessment of this pathology in France...
  27. ncbi Update of Clostridium difficile-associated disease due to PCR ribotype 027 in Europe
    E J Kuijper
    National Reference Laboratory for Clostridium difficile, Leiden University Medical Centre, Leiden, The Netherlands
    Euro Surveill 12:E1-2. 2007
    ..Preliminary data indicated that type 027 was already present in historical isolates collected in Sweden between 1997 and 2001...
  28. ncbi Emergence of Clostridium difficile toxinotype III, PCR-ribotype 027-associated disease, France, 2006
    B Coignard
    , Institut de Veille Sanitaire, Saint-Maurice, France
    Euro Surveill 11:E060914.1. 2006
  29. ncbi First cluster of C. difficile toxinotype III, PCR-ribotype 027 associated disease in France: preliminary report
    M Tachon
    Centre Hospitalier, Valenciennes, France
    Euro Surveill 11:E060504.1. 2006
  30. ncbi Infection control measures to limit the spread of Clostridium difficile
    R P Vonberg
    Institute for Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany
    Clin Microbiol Infect 14:2-20. 2008
    ..Existing local protocols and practices for the control of C. difficile should be carefully reviewed and modified if necessary...
  31. ncbi [Clostridium difficile infections: an unexpected re-emergence]
    F Barbut
    Pathol Biol (Paris) 56:6-9. 2008