Research Topics
| P Barberger-GateauSummaryCountry: France Publications
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Publications
Dietary patterns and risk of dementia: the Three-City cohort studyP Barberger-Gateau
INSERM, U593, University Victor Segalen Bordeaux 2, Case 11, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
Neurology 69:1921-30. 2007..The aim of our study was to analyze the relationship between dietary patterns and risk of dementia or Alzheimer disease (AD), adjusting for sociodemographic and vascular risk factors, and taking into account the ApoE genotype...
Fish, meat, and risk of dementia: cohort studyPascale Barberger-Gateau
INSERM U330, , case n degrees 11, , 33076 Bordeaux Cedex, France
BMJ 325:932-3. 2002
Correlates of regular fish consumption in French elderly community dwellers: data from the Three-City studyP Barberger-Gateau
INSERM U593, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Eur J Clin Nutr 59:817-25. 2005..The objective of this study was to describe the characteristics of older fish consumers, in order to identify potential confounders in this relationship...
Dietary omega 3 polyunsaturated fatty acids and Alzheimer's disease: interaction with apolipoprotein E genotypeP Barberger-Gateau
INSERM, U897, Bordeaux, F 33076 France
Curr Alzheimer Res 8:479-91. 2011..Further research is needed to explain the differential effect of n-3 PUFA on AD according to ApoE genotype...
The contribution of dementia to the disablement process and modifying factorsPascale Barberger-Gateau
Epidemiology, Public Health and Development INSERM U593, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Dement Geriatr Cogn Disord 18:330-7. 2004..Dementia did not increase the risk of death, once disability was taken into account, except from the lowest disability grade...
[Quasi-experimental evaluation of a nutritional educational intervention among home support assistants for the elderly]P Barberger-Gateau
Unité INSERM U593 Epidémiologie, Santé Publique et Développement, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex
Rev Epidemiol Sante Publique 54:233-43. 2006..The objective of our study was to evaluate the impact of a nutritional education intervention on knowledge and practices among home support assistants for the elderly...
Occupation during life and risk of dementia in French elderly community residentsC Helmer
INSERM U 330, Universite de Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
J Neurol Neurosurg Psychiatry 71:303-9. 2001..To determine whether principal occupation during life is a risk factor for incident Alzheimer's disease, vascular dementia, or dementia with parkinsonism...
Neuropsychological correlates of self-reported performance in instrumental activities of daily living and prediction of dementiaP Barberger-Gateau
INSERM 330, Universite Victor Segalen, Bordeaux, France
J Gerontol B Psychol Sci Soc Sci 54:P293-303. 1999..Only the first factor was predictive of the risk of incident dementia, suggesting that the predictive value of the 4 IADL was explained by their cognitive component...
Intake of flavonoids and risk of dementiaD Commenges
Institut National de la Santé et de la Recherche Médicale U330, Bordeaux, France
Eur J Epidemiol 16:357-63. 2000..After additional adjustment for gender, education, weight and vitamin C intake, the RR was 0.49 (95% CI: 0.26-0.92; p = 0.04). We conclude that the intake of antioxidant flavonoids is inversely related to the risk of incident dementia...
Olive oil consumption, plasma oleic acid, and stroke incidence: the Three-City StudyC Samieri
Research Center INSERM, U897, Department of Nutritional Epidemiology, Bordeaux, France
Neurology 77:418-25. 2011..To determine whether high olive oil consumption, and high plasma oleic acid as an indirect biological marker of olive oil intake, are associated with lower incidence of stroke in older subjects...
A hierarchical model of domains of disablement in the elderly: a longitudinal approachP Barberger-Gateau
INSERM U330, Universite Victor Segalen Bordeaux 2, France
Disabil Rehabil 22:308-17. 2000....
Nutritional factors in cerebral aging and dementia: epidemiological arguments for a role of oxidative stressV Deschamps
INSERM U330, Universite Victor Segalen, Bordeaux, France
Neuroepidemiology 20:7-15. 2001..Vascular dementia and Alzheimer's disease, that share several risk factors, might be targets for primary prevention through nutritional recommendations and/or supplementation...
Oral health condition of French elderly and risk of dementia: a longitudinal cohort studyE Arrive
Department of Oral Health, Universite Victor Segalen, Bordeaux, France
Community Dent Oral Epidemiol 40:230-8. 2012..The objective of this study thus was to describe the oral condition of French community-dwelling elderly persons and to assess its relationship with the occurrence of dementia...
Association between antioxidant nutritional indicators and the incidence of dementia: results from the PAQUID prospective cohort studyC Helmer
INSERM U 330, Universite de Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
Eur J Clin Nutr 57:1555-61. 2003..To analyse the relation between antioxidant vitamins A, E, and malondialdehyde (MDA) lipoperoxidation product plasma concentrations with incident dementia...
Nutrition and age-related eye diseases: the Alienor (Antioxydants, Lipides Essentiels, Nutrition et maladies OculaiRes) StudyC Delcourt
INSERM U897, Universite Victor Segalen Bordeaux 2, Bordeaux, France
J Nutr Health Aging 14:854-61. 2010..Few epidemiological studies have been conducted in this field, particularly in Europe...
The disablement process: a conceptual framework for dementia-associated disabilityP Barberger-Gateau
INSERM U330, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Dement Geriatr Cogn Disord 13:60-6. 2002..We show how the model can help in understanding the functional consequences of dementia, for better assessment and management of demented subjects...
Nutritional status of healthy elderly persons living in Dordogne, France, and relation with mortality and cognitive or functional declineV Deschamps
INSERM U330, Universite Victor Segalen Bordeaux 2, France
Eur J Clin Nutr 56:305-12. 2002..Description of the nutritional status of healthy elderly people and investigation of its longitudinal relationship with mortality and cognitive or functional decline...
Flavonoid intake and cognitive decline over a 10-year periodL Letenneur
INSERM, Unité 593, Bordeaux, France
Am J Epidemiol 165:1364-71. 2007..2 points. This gradient persisted after adjustment for several other potential confounders. This study raises the possibility that dietary flavonoid intake is associated with better cognitive evolution...
Risk adjustment of quality indicators in French long term care facilities for elderly people. A preliminary studyC Moty
Centre Hospitalier Universitaire de Bordeaux, Unité INSERM 593 ex 330, Institut de Santé Publique, d Épidémiologie et de Développement, Universite Victor Segalen Bordeaux 2, rue Leo Saignat, 33076 Bordeaux Cedex, France
Rev Epidemiol Sante Publique 51:327-38. 2003..The objective of this preliminary study was to propose risk adjustments on the CHSRA indicators for future use in France...
Detection of depressive symptomatology in elderly people: a short version of the CES-D scaleI Rouch-Leroyer
INSERM U 330, Universite Victor Segalen Bordeaux 2, France
Aging (Milano) 12:228-33. 2000..In conclusion, the 5-item CES-D is a simple, rapid and reliable tool which could be useful for screening depressive symptoms in epidemiological studies of the elderly...
Dependency in Parkinson's disease: a population-based survey in nondemented elderly subjectsF Tison
Department of Neurology, Pellegrin Hospital, Bordeaux, France
Mov Disord 12:910-5. 1997..Institutionalization occurred over four times more frequently in the PD group than in the general population, but no specific factor of institutionalization was noted...
Metabolic syndrome and cognitive decline in French elders: the Three-City StudyC Raffaitin
Diabetology Nutrition Unit, University Hospital of Bordeaux, Pessac, France
Neurology 76:518-25. 2011..To examine associations between metabolic syndrome (MetS) and its individual components with risk of cognitive decline on specific cognitive functions...
Accelerated degradation model and its applications to statistical analysis of the role played by dementia and sex in the loss of functional autonomy in elderly patientsM Nikulin
Statistique Mathématique, Universite Bordeaux 2, France
Adv Gerontol 19:44-54. 2006..The conjoint accelerated degradation model for statistical analysis of survival and degradation data is discussed...
Restriction in complex activities of daily living in MCI: impact on outcomeK Peres
INSERM U593 the French Institute of Health and Medical Research, University Victor Segalen, France
Neurology 67:461-6. 2006..To describe the restriction in instrumental activities of daily living (IADL) in mild cognitive impairment (MCI) and to assess the impact of IADL restriction on the progression to dementia and on MCI reversibility...
Sociodemographic differences in dietary habits in a population-based sample of elderly subjects: the 3C studyS Larrieu
Epidemiology Research Unit, Institut National de la Santé et de la Recherche Médicale INSERM U 593, 33 076 Bordeaux Cedex, France
J Nutr Health Aging 8:497-502. 2004..We aimed to describe dietary habits in a large population-based sample of elderly people and to explore how they may vary according to sex, age, educational level and lifestyle...
Relationship between body mass index and different domains of disability in older persons: the 3C studyS Larrieu
Epidemiology Research Unit, Institut National de la Santé et de la Recherche Médicale INSERM U 593, 33 076 Bordeaux, France
Int J Obes Relat Metab Disord 28:1555-60. 2004..To study the relationships between body mass index (BMI) and different domains of disability in elderly subjects from the French 3C study...
Nutritional factors and risk of incident dementia in the PAQUID longitudinal cohortS Larrieu
Epidemiology Research Unit, Institut National de la Santé et de la Recherche Médicale INSERM U593, Bordeaux Cedex, France
J Nutr Health Aging 8:150-4. 2004..The aim of this study was to present a summary of the results obtained in the PAQUID study regarding wine consumption, fish and seafood consumption and vitamin A and E plasma concentrations...
Incidence and outcome of mild cognitive impairment in a population-based prospective cohortS Larrieu
Epidemiology Research Unit, Institut National de la Santé et de la Recherche Médicale INSERM U 330, France
Neurology 59:1594-9. 2002..To estimate the age-specific incidence rate of mild cognitive impairment (MCI) according to sex and educational level and to explore the course of MCI, particularly its progression to AD, in a population-based cohort...
[Prevalence of dementia and Alzheimer's disease among subjects aged 75 years or over: updated results of the PAQUID cohort]H Ramaroson
Unité INSERM 330, Université Victor Segalen Bordeaux II
Rev Neurol (Paris) 159:405-11. 2003..These results point out the importance of regarding dementia as a Public Health priority and of developing necessary measures for caring for these subjects, whether residing in their home or an institution...
Subjective health and mortality in French elderly women and menC Helmer
INSERM Institut National de la Santé et de la Recherche Médicale, Universite de Bordeaux II, France
J Gerontol B Psychol Sci Soc Sci 54:S84-92. 1999..To examine the predictive value of subjective health on mortality separately in women and men, independently of other health measures, and to explain the differences between sexes by way of cognition, depression, and disability...
Dyspnea and 8-year mortality among elderly men and women: the PAQUID cohort studyJ F Tessier
INSERM U330, ISPED, Universite Bordeaux II, France
Eur J Epidemiol 17:223-9. 2001..These results show that dyspnea grade 3 or higher is an important predictive symptom of mortality, thus suggesting that this is a threshold defining the dyspneic subject...
Mortality of elderly subjects with self-reported asthma in a French cohort, 1991-1996C Dantzer
INSERM U330, University of Victor Segalen, Bordeaux 2, France
Eur J Epidemiol 17:57-63. 2001..1-1.9; p = 0.009). This risk was significant (RR: 1.4; 95% CI: 1.05-1.8; p = 0.02) even after adjustment on morbidity variables. However no specific mortality risk factors were found for subjects with self-reported asthma...
[Incidence, risk factors and adequation of early readmission among the elderly]K Peres
INSERM U330, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
Rev Epidemiol Sante Publique 50:109-19. 2002....
The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based studyHelene Amieva
INSERM Institut National de la Santé et de la Recherche Médicale Unit 593, Bordeaux, France
Brain 128:1093-101. 2005....
Natural history of decline in instrumental activities of daily living performance over the 10 years preceding the clinical diagnosis of dementia: a prospective population-based studyKarine Pérès
Institut National de la Santé et de la Recherche Médicale U593, Bordeaux, France
J Am Geriatr Soc 56:37-44. 2008..To study the subtle changes in instrumental activities of daily living (IADLs) over the 10 years preceding the clinical diagnosis of dementia...
Tea consumption is inversely associated with carotid plaques in womenStephanie Debette
INSERM, U744, Lille, France
Arterioscler Thromb Vasc Biol 28:353-9. 2008..The aim of this study was to assess the relationship of tea consumption with common carotid artery intima-media thickness (CCA-IMT) and carotid plaques...
Plasma eicosapentaenoic acid is inversely associated with severity of depressive symptomatology in the elderly: data from the Bordeaux sample of the Three-City StudyCatherine Feart
INSERM U593, Equipe Epidémiologie de la Nutrition et des Comportements Alimentaires, Bordeaux, France
Am J Clin Nutr 87:1156-62. 2008..Depressive symptoms are commonly observed in elderly people, and nutritional factors such as polyunsaturated fatty acids (PUFAs) have been proposed as potential protective determinants of depressive disorders...
Dietary patterns derived by hybrid clustering method in older people: association with cognition, mood, and self-rated healthCecilia Samieri
INSERM, U897, University Victor Segalen Bordeaux 2, Case 11, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
J Am Diet Assoc 108:1461-71. 2008..Dietary patterns that represent a combination of foods may better predict disease risk than single foods or nutrients...
Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia riskCecilia Samieri
INSERM, U897, Equipe Epidémiologie de Nutrition et des Comportements Alimentaires, Bordeaux, France
Am J Clin Nutr 88:714-21. 2008..Plasma n-3 PUFAs have been shown to be inversely related to the risk of dementia and to depression, which is frequently associated with dementia...
Macronutrient intake and discrepancy with nutritional recommendations in a group of elderly diabetic subjectsCatherine Helmer
INSERM, U593, 146 rue Leo Saignat, Bordeaux Cedex, France
Br J Nutr 99:632-8. 2008..These results should be taken into account to adapt nutritional advice given to the diabetic population...
Re: Bell-McGinty et al standard measures of executive function in predicting instrumental activities of daily living in older adultsPascale Barberger-Gateau
Int J Geriatr Psychiatry 18:459-60. 2003
Disability in older people--indicators, process and outcomesCarol Jagger
Disabil Rehabil 27:209-12. 2005
The disablement process: factors associated with progression of disability and recovery in French elderly peopleKarine Pérès
INSERM U593, University of Bordeau x 2, France
Disabil Rehabil 27:263-76. 2005..To study the factors associated with progression, recovery and death from different grades of disability in elderly people...
Ten-year change in disability prevalence and related factors in two generations of French elderly community dwellers: data from the PAQUID studyKarine Pérès
INSERM U593, Case 11, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
Aging Clin Exp Res 17:229-35. 2005..Our aim was to study the 10-year evolution of disability prevalence in elderly community dwellers and related factors...
Dementia in subjects aged 75 years or over within the PAQUID cohort: prevalence and burden by severityCatherine Helmer
INSERM U 593 Université de Bordeaux 2, Bordeaux, France
Dement Geriatr Cogn Disord 22:87-94. 2006..To analyze the prevalence of dementia by severity and to describe the sociodemographic characteristics of people with dementia in the community, as well as the consequences of this disease in terms of disability and institutionalization...
Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA StudyCécile Delcourt
Institut National de la Sante et de la Recherche Medicale INSERM, Research Unit U593 for Epidemiology, Public Health and Development, Universite Victor Segalen Bordeaux 2, Bordeaux, France
Invest Ophthalmol Vis Sci 47:2329-35. 2006..To assess the associations of plasma lutein and zeaxanthin and other carotenoids with the risk of age-related maculopathy (ARM) and cataract in the population-based Pathologies Oculaires Liées à l'Age (POLA) Study...
Annual rate and predictors of conversion to dementia in subjects presenting mild cognitive impairment criteria defined according to a population-based studyHelene Amieva
INSERM Unit 593, Universite Victor Segalen, Bordeaux, France
Dement Geriatr Cogn Disord 18:87-93. 2004..Among the variables considered, the Letter Cancellation Test proved to be a major predictor of short-term conversion to dementia...
Preferences for routines in older people: associations with cognitive and psychological vulnerabilityValérie Bergua
Clinical Psychological Research Laboratory JE 2358, University of Bordeaux 2 3, ter Place de la Victoire, Bordeaux Cedex, France
Int J Geriatr Psychiatry 21:990-8. 2006..Although routine activities are important to normal functioning across all phases of life, their expression in older people may be associated with cognitive and psychological vulnerability...
Alcohol and tobacco consumption as risk factors of dementia: a review of epidemiological studiesLuc Letenneur
INSERM U 593, Case 11, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
Biomed Pharmacother 58:95-9. 2004..These results suggest that tobacco consumption is not associated with a lower risk of dementia and that moderate alcohol intake does not increase the risk of developing dementia...
Evolution of prevalence of depressive symptoms and antidepressant use between 1988 and 1999 in a large sample of older French people: Results from the personnes agées quid studyDelphine Montagnier
Department of Geriatrics, CHU Bordeaux, Hopital Xavier Arnozan, Pessac, France
J Am Geriatr Soc 54:1839-45. 2006..To describe the evolution of prevalence of depressive symptoms and antidepressant use between 1988 and 1999 in a large representative sample of older community-dwelling French people...
Energy, macronutrient and fatty acid intake of French elderly community dwellers and association with socio-demographic characteristics: data from the Bordeaux sample of the Three-City StudyCatherine Feart
INSERM U593, Universite Bordeaux 2, France
Br J Nutr 98:1046-57. 2007..9 and decreased with higher educational level. The present results suggest that being female, older age, being widowed and low income level could be considered as risk factors of inadequate dietary intake...
Research criteria for the diagnosis of Alzheimer's disease: revising the NINCDS-ADRDA criteriaBruno Dubois
INSERM U610, Hopital de la Salpetriere, Paris, France
Lancet Neurol 6:734-46. 2007..Validation studies in existing and prospective cohorts are needed to advance these criteria and optimise their sensitivity, specificity, and accuracy...
