Boyer J, Baron M, Constantin A, DegboÃ© Y, Cantagrel A, Davignon J. Anti-TNF certolizumab pegol induces antioxidant response in human monocytes via reverse signaling. Arthritis Res Ther. 2016;18:56 pubmed publisher
..Our data suggest a novel mechanism of ROS modulation by CZP. This observation sheds new light on the function of reverse signaling and on potential mechanisms of action of anti-TNF drugs. ..
Degboé Y, Fruchon S, Baron M, Nigon D, Turrin C, Caminade A, et al
. Modulation of pro-inflammatory activation of monocytes and dendritic cells by aza-bis-phosphonate dendrimer as an experimental therapeutic agent. Arthritis Res Ther. 2014;16:R98 pubmed publisher
..Our data indicate that dendrimer ABP possesses immunomodulatory properties on human Mo and MoDC, in TLR4 + IFN-? stimulation model, by inducing M2 alternative activation of Mo and promoting tolerogenic MoDC. ..