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Species | Maxim Y BalakirevSummaryCountry: France Publications
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Publications
Otubains: a new family of cysteine proteases in the ubiquitin pathwayMaxim Y Balakirev
Departement de Reponse et Dynamique Cellulaires, Commisariat à l Energie Atomique, 17 rue des Martyrs, Grenoble 38054, France
EMBO Rep 4:517-22. 2003..We have named these proteins otubain 1 and otubain 2, for OTU-domain Ubal-binding protein. Functional analysis of otubains shows that the OTU domain contains an active cysteine protease site...
Photochemical patterning of biological molecules inside a glass capillaryMaxim Y Balakirev
Laboratoire Biopuces, Departement Reponse et Dynamique Cellulaires, and Laboratoire d Electronique de Technologie de l Information LETI, Commissariat a l Energie Atomique, 17 rue des Martyrs, 38054 Grenoble, France
Anal Chem 77:5474-9. 2005..The capillary format should therefore be considered as a possible alternative to a planar format in a number of low-density array applications such as mutation detection and diagnostic immunoassays...- Chemoenzymatic ubiquitination of artificial substratesOlga N Burchak
, , 17 rue des Martyrs, 38054 Grenoble, France
Chembiochem 7:1667-9. 2006 - Fluorogenic ester substrates to assess proteolytic activityLaurent Mugherli
Laboratoire Biopuces, , , Grenoble, France
Bioorg Med Chem Lett 16:4488-91. 2006..The substrate cleavage is sensitive to specific protease inhibitors providing a tool for inhibitor screening... - Deubiquitinating function of adenovirus proteinaseMaxim Y Balakirev
Institut de Biologie Structurale, Grenoble 38027 Département de Biologie Moléculaire et Structurale, CEA, Grenoble 38054, France
J Virol 76:6323-31. 2002..These results may reflect the acquisition of an advantageous property by adenovirus and may indicate the importance of ubiquitin pathways in viral infection... 
Combinatorial discovery of fluorescent pharmacophores by multicomponent reactions in droplet arraysOlga N Burchak
Biomics Laboratory, Institut de Recherches en Technologies et Sciences pour le Vivant, CEA, 17 rue des Martyrs, 38054 Grenoble, France
J Am Chem Soc 133:10058-61. 2011..Because they are based upon a druglike scaffold, these fluorophores retain their molecular recognition potential and can be used to design specific imaging probes...- Fluorescein-based amino acids for solid phase synthesis of fluorogenic protease substratesOlga N Burchak
Laboratoire Biopuces, , , 17 rue des Martyrs, 38054 Grenoble, France
Bioorg Med Chem 14:2559-68. 2006..The new type fluorescent amino acids seem to be a promising tool for the synthesis of fluorescent peptide ligands and fluorogenic protease substrates... - Crystal structure of human otubain 2Max H Nanao
Laboratoire de Cristallographie Macromoléculaire, Institut de Biologie Structurale JP Ebel CEA CNRS UJF, 41 rue Jules Horowitz, 38027 Grenoble, France
EMBO Rep 5:783-8. 2004..This reorganization of the active-site topology provides a possible explanation for the low turnover and substrate specificity of the otubains... - Construction of tumor-specific toxins using ubiquitin fusion techniqueSergey O Tcherniuk
Laboratoire de Biophysique Moleculaire, Institut de Biologie Structurale J P Ebel CEA CNRS UJF, 41 rue Jules Horowitz, 38027 Grenoble, France
Mol Ther 11:196-204. 2005..The ubiquitin fusion technique is thus a versatile and reliable method for obtaining selective cytotoxic agents and can easily be adapted for different kinds of toxins and activating proteases... - OTU takes the chains OUTMaxim Y Balakirev
Nat Chem Biol 4:227-8. 2008