Maxim Y Balakirev

Summary

Country: France

Publications

  1. pmc Otubains: a new family of cysteine proteases in the ubiquitin pathway
    Maxim Y Balakirev
    Departement de Reponse et Dynamique Cellulaires, Commisariat à l Energie Atomique, 17 rue des Martyrs, Grenoble 38054, France
    EMBO Rep 4:517-22. 2003
  2. ncbi Photochemical patterning of biological molecules inside a glass capillary
    Maxim Y Balakirev
    Laboratoire Biopuces, Departement Reponse et Dynamique Cellulaires, and Laboratoire d Electronique de Technologie de l Information LETI, Commissariat a l Energie Atomique, 17 rue des Martyrs, 38054 Grenoble, France
    Anal Chem 77:5474-9. 2005
  3. ncbi Chemoenzymatic ubiquitination of artificial substrates
    Olga N Burchak
    Departement Reponse et Dynamique Cellulaires, Commissariat a l Energie Atomique, 17 rue des Martyrs, 38054 Grenoble, France
    Chembiochem 7:1667-9. 2006
  4. ncbi Fluorogenic ester substrates to assess proteolytic activity
    Laurent Mugherli
    Laboratoire Biopuces, Departement Reponse et Dynamique Cellulaires, Commissariat a l Energie Atomique, Grenoble, France
    Bioorg Med Chem Lett 16:4488-91. 2006
  5. pmc Deubiquitinating function of adenovirus proteinase
    Maxim Y Balakirev
    Institut de Biologie Structurale, Grenoble 38027 Département de Biologie Moléculaire et Structurale, CEA, Grenoble 38054, France
    J Virol 76:6323-31. 2002
  6. ncbi Fluorescein-based amino acids for solid phase synthesis of fluorogenic protease substrates
    Olga N Burchak
    Laboratoire Biopuces, Departement Reponse et Dynamique Cellulaires, Commissariat a l Energie Atomique, 17 rue des Martyrs, 38054 Grenoble, France
    Bioorg Med Chem 14:2559-68. 2006
  7. doi Combinatorial discovery of fluorescent pharmacophores by multicomponent reactions in droplet arrays
    Olga N Burchak
    Biomics Laboratory, Institut de Recherches en Technologies et Sciences pour le Vivant, CEA, 17 rue des Martyrs, 38054 Grenoble, France
    J Am Chem Soc 133:10058-61. 2011
  8. pmc Crystal structure of human otubain 2
    Max H Nanao
    Laboratoire de Cristallographie Macromoléculaire, Institut de Biologie Structurale JP Ebel CEA CNRS UJF, 41 rue Jules Horowitz, 38027 Grenoble, France
    EMBO Rep 5:783-8. 2004
  9. ncbi Construction of tumor-specific toxins using ubiquitin fusion technique
    Sergey O Tcherniuk
    Laboratoire de Biophysique Moleculaire, Institut de Biologie Structurale J P Ebel CEA CNRS UJF, 41 rue Jules Horowitz, 38027 Grenoble, France
    Mol Ther 11:196-204. 2005
  10. doi OTU takes the chains OUT
    Maxim Y Balakirev
    Nat Chem Biol 4:227-8. 2008

Collaborators

Detail Information

Publications10

  1. pmc Otubains: a new family of cysteine proteases in the ubiquitin pathway
    Maxim Y Balakirev
    Departement de Reponse et Dynamique Cellulaires, Commisariat à l Energie Atomique, 17 rue des Martyrs, Grenoble 38054, France
    EMBO Rep 4:517-22. 2003
    ..We have named these proteins otubain 1 and otubain 2, for OTU-domain Ubal-binding protein. Functional analysis of otubains shows that the OTU domain contains an active cysteine protease site...
  2. ncbi Photochemical patterning of biological molecules inside a glass capillary
    Maxim Y Balakirev
    Laboratoire Biopuces, Departement Reponse et Dynamique Cellulaires, and Laboratoire d Electronique de Technologie de l Information LETI, Commissariat a l Energie Atomique, 17 rue des Martyrs, 38054 Grenoble, France
    Anal Chem 77:5474-9. 2005
    ..The capillary format should therefore be considered as a possible alternative to a planar format in a number of low-density array applications such as mutation detection and diagnostic immunoassays...
  3. ncbi Chemoenzymatic ubiquitination of artificial substrates
    Olga N Burchak
    Departement Reponse et Dynamique Cellulaires, Commissariat a l Energie Atomique, 17 rue des Martyrs, 38054 Grenoble, France
    Chembiochem 7:1667-9. 2006
  4. ncbi Fluorogenic ester substrates to assess proteolytic activity
    Laurent Mugherli
    Laboratoire Biopuces, Departement Reponse et Dynamique Cellulaires, Commissariat a l Energie Atomique, Grenoble, France
    Bioorg Med Chem Lett 16:4488-91. 2006
    ..The substrate cleavage is sensitive to specific protease inhibitors providing a tool for inhibitor screening...
  5. pmc Deubiquitinating function of adenovirus proteinase
    Maxim Y Balakirev
    Institut de Biologie Structurale, Grenoble 38027 Département de Biologie Moléculaire et Structurale, CEA, Grenoble 38054, France
    J Virol 76:6323-31. 2002
    ..These results may reflect the acquisition of an advantageous property by adenovirus and may indicate the importance of ubiquitin pathways in viral infection...
  6. ncbi Fluorescein-based amino acids for solid phase synthesis of fluorogenic protease substrates
    Olga N Burchak
    Laboratoire Biopuces, Departement Reponse et Dynamique Cellulaires, Commissariat a l Energie Atomique, 17 rue des Martyrs, 38054 Grenoble, France
    Bioorg Med Chem 14:2559-68. 2006
    ..The new type fluorescent amino acids seem to be a promising tool for the synthesis of fluorescent peptide ligands and fluorogenic protease substrates...
  7. doi Combinatorial discovery of fluorescent pharmacophores by multicomponent reactions in droplet arrays
    Olga N Burchak
    Biomics Laboratory, Institut de Recherches en Technologies et Sciences pour le Vivant, CEA, 17 rue des Martyrs, 38054 Grenoble, France
    J Am Chem Soc 133:10058-61. 2011
    ..Because they are based upon a druglike scaffold, these fluorophores retain their molecular recognition potential and can be used to design specific imaging probes...
  8. pmc Crystal structure of human otubain 2
    Max H Nanao
    Laboratoire de Cristallographie Macromoléculaire, Institut de Biologie Structurale JP Ebel CEA CNRS UJF, 41 rue Jules Horowitz, 38027 Grenoble, France
    EMBO Rep 5:783-8. 2004
    ..This reorganization of the active-site topology provides a possible explanation for the low turnover and substrate specificity of the otubains...
  9. ncbi Construction of tumor-specific toxins using ubiquitin fusion technique
    Sergey O Tcherniuk
    Laboratoire de Biophysique Moleculaire, Institut de Biologie Structurale J P Ebel CEA CNRS UJF, 41 rue Jules Horowitz, 38027 Grenoble, France
    Mol Ther 11:196-204. 2005
    ..The ubiquitin fusion technique is thus a versatile and reliable method for obtaining selective cytotoxic agents and can easily be adapted for different kinds of toxins and activating proteases...
  10. doi OTU takes the chains OUT
    Maxim Y Balakirev
    Nat Chem Biol 4:227-8. 2008