Jean Francois Bach

Summary

Country: France

Publications

  1. ncbi Six questions about the hygiene hypothesis
    Jean Francois Bach
    Hopital Necker Enfants Malades, Service d Immunologie, 149 rue de Sevres, Paris, France
    Cell Immunol 233:158-61. 2005
  2. ncbi Long-term reversal of established autoimmunity upon transient blockade of the LFA-1/intercellular adhesion molecule-1 pathway
    Lydia Bertry-Coussot
    Institut National de la Sante et de la Recherche Medicale, Unité 25, Equipe 0016, Universite Rene Descartes, Paris, France
    J Immunol 168:3641-8. 2002
  3. pmc Immunotherapy of type 1 diabetes: lessons for other autoimmune diseases
    Jean Francois Bach
    INSERM U 25, Hopital Necker, Paris, France
    Arthritis Res 4:S3-15. 2002
  4. pmc Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target
    Sylvaine You
    Universite Paris Descartes, Paris, France
    PLoS ONE 4:e7848. 2009
  5. pmc Adaptive human regulatory T cells: myth or reality?
    Lucienne Chatenoud
    Universite Rene Descartes Paris 5, INSERM U580, Hopital Necker Enfants Malades, Paris, France
    J Clin Invest 116:2325-7. 2006
  6. ncbi Regulatory T cells in the control of autoimmune diabetes: the case of the NOD mouse
    Lucienne Chatenoud
    Universite Rene Descartes, INSERM U580 Hôpital Necker, Paris, France
    Int Rev Immunol 24:247-67. 2005
  7. ncbi G-CSF therapy of ongoing experimental allergic encephalomyelitis via chemokine- and cytokine-based immune deviation
    Flora Zavala
    Institut National de la Sante et de la Recherche Medical, Unité 25 and Unité 345, Necker Hospital, Paris, France Sanofi Synthelabo, Bagneux, France
    J Immunol 168:2011-9. 2002
  8. ncbi The effect of infections on susceptibility to autoimmune and allergic diseases
    Jean Francois Bach
    INSERM Unité 25, Institut de Recherches Necker Enfants Malades, Hopital Necker, Paris, France
    N Engl J Med 347:911-20. 2002
  9. pmc The role of innate immunity in autoimmunity
    Jean Francois Bach
    INSERM U580, Hopital Necker, Paris, France
    J Exp Med 200:1527-31. 2004
  10. pmc Systemic Toll-like receptor stimulation suppresses experimental allergic asthma and autoimmune diabetes in NOD mice
    Aude Aumeunier
    Universite Paris Descartes, Paris, France
    PLoS ONE 5:e11484. 2010

Collaborators

Detail Information

Publications15

  1. ncbi Six questions about the hygiene hypothesis
    Jean Francois Bach
    Hopital Necker Enfants Malades, Service d Immunologie, 149 rue de Sevres, Paris, France
    Cell Immunol 233:158-61. 2005
    ....
  2. ncbi Long-term reversal of established autoimmunity upon transient blockade of the LFA-1/intercellular adhesion molecule-1 pathway
    Lydia Bertry-Coussot
    Institut National de la Sante et de la Recherche Medicale, Unité 25, Equipe 0016, Universite Rene Descartes, Paris, France
    J Immunol 168:3641-8. 2002
    ..Rather, sICAM-1/Ig induced active tolerance, as assessed by the persistence of diabetogenic T cells in protected mice and the reversal of protection by immunosuppression with cyclophosphamide...
  3. pmc Immunotherapy of type 1 diabetes: lessons for other autoimmune diseases
    Jean Francois Bach
    INSERM U 25, Hopital Necker, Paris, France
    Arthritis Res 4:S3-15. 2002
    ..Most of the concepts and strategies derived from this model apply to other autoimmune diseases, for which no such diversified data are available...
  4. pmc Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target
    Sylvaine You
    Universite Paris Descartes, Paris, France
    PLoS ONE 4:e7848. 2009
    ..In this study, we examined the role of GITR/GITRLigand interaction in the progression of autoimmune diabetes...
  5. pmc Adaptive human regulatory T cells: myth or reality?
    Lucienne Chatenoud
    Universite Rene Descartes Paris 5, INSERM U580, Hopital Necker Enfants Malades, Paris, France
    J Clin Invest 116:2325-7. 2006
    ..It is thus unlikely that all CD4+ CD25hi Foxp3+ Tregs are generated as a separate lineage in the thymus. The authors propose that during adulthood, Tregs essentially emerge at the periphery from the memory T cell pool...
  6. ncbi Regulatory T cells in the control of autoimmune diabetes: the case of the NOD mouse
    Lucienne Chatenoud
    Universite Rene Descartes, INSERM U580 Hôpital Necker, Paris, France
    Int Rev Immunol 24:247-67. 2005
    ....
  7. ncbi G-CSF therapy of ongoing experimental allergic encephalomyelitis via chemokine- and cytokine-based immune deviation
    Flora Zavala
    Institut National de la Sante et de la Recherche Medical, Unité 25 and Unité 345, Necker Hospital, Paris, France Sanofi Synthelabo, Bagneux, France
    J Immunol 168:2011-9. 2002
    ..These findings support the potential application of G-CSF in the treatment of human autoimmune diseases such as multiple sclerosis, taking advantage of the wide clinical favorable experience with this molecule...
  8. ncbi The effect of infections on susceptibility to autoimmune and allergic diseases
    Jean Francois Bach
    INSERM Unité 25, Institut de Recherches Necker Enfants Malades, Hopital Necker, Paris, France
    N Engl J Med 347:911-20. 2002
  9. pmc The role of innate immunity in autoimmunity
    Jean Francois Bach
    INSERM U580, Hopital Necker, Paris, France
    J Exp Med 200:1527-31. 2004
    ....
  10. pmc Systemic Toll-like receptor stimulation suppresses experimental allergic asthma and autoimmune diabetes in NOD mice
    Aude Aumeunier
    Universite Paris Descartes, Paris, France
    PLoS ONE 5:e11484. 2010
    ..We have tested whether Toll-like receptor (TLR) stimulation can recapitulate the protective effect of infectious agents on allergy and autoimmunity...
  11. doi The etiology of autoimmune diseases: the case of myasthenia gravis
    Jean Francois Bach
    Academie des sciences, Paris, France
    Ann N Y Acad Sci 1274:33-9. 2012
    ..In this article I will attempt to analyze the various factors that have a triggering or protecting role, with particular reference to myasthenia gravis...
  12. ncbi The protective effect of infections on immune disorders
    Jean Francois Bach
    INSERM, Hopital Necker, Paris, France
    J Pediatr Gastroenterol Nutr 40:S8. 2005
  13. pmc Genetic control of hepatitis A severity and susceptibility to allergy
    Lucienne Chatenoud
    Universite Paris Descartes, INSERM, Paris, France
    J Clin Invest 121:848-50. 2011
    ..Importantly, this TIM1 gene polymorphism protects from the development of atopic diseases in HAV-seropositive individuals...
  14. ncbi Transforming growth factor-beta and T-cell-mediated immunoregulation in the control of autoimmune diabetes
    Sylvaine You
    Universite Rene Descartes Paris 5, Institut National de la Santé et de la Recherche Médicale U580 and Hôpital Necker Enfants Malades, Paris, France
    Immunol Rev 212:185-202. 2006
    ..Herein we discuss these results and the working hypothesis they evoke in the context of the present literature, where the role of TGF-beta-dependent T-cell-mediated immunoregulation is still debated...
  15. ncbi Concomitant early appearance of anti-ribonucleoprotein and anti-nucleosome antibodies in lupus prone mice
    Diego Laderach
    INSERM U25, Hopital Necker, 161 rue de Sevres, 75743 Cedex 15, Paris, France
    J Autoimmun 20:161-70. 2003
    ....