Marie Claude Babron

Summary

Country: France

Publications

  1. ncbi request reprint Genetic interaction of CTLA-4 with HLA-DR15 in multiple sclerosis patients
    Mehdi Alizadeh
    Laboratoire Universitaire d Immunologie UPRES EA 1257, IFR 97 and Etablissement Français du Sang Bretagne, Faculte de Medecine, Rennes, France
    Ann Neurol 54:119-22. 2003
  2. ncbi request reprint Meta and pooled analysis of European coeliac disease data
    Marie Claude Babron
    1INSERM U535, Villejuif, France
    Eur J Hum Genet 11:828-34. 2003
  3. pmc An ordered subset approach to including covariates in the transmission disequilibrium test
    Hervé Perdry
    INSERM U535, BP 1000, Villejuif, 94817, France
    BMC Proc 1:S77. 2007
  4. pmc On the choice of linkage statistics
    Patricia Margaritte Jeannin
    INSERM U535, F 94817 Villejuif, France
    BMC Proc 1:S102. 2007
  5. pmc Detection of susceptibility loci by genome-wide linkage analysis
    Marie Claude Babron
    INSERM U535, 94817 Villejuif Cedex, Villejuif, France
    BMC Genet 6:S18. 2005
  6. pmc Modeling the effect of a genetic factor for a complex trait in a simulated population
    Mathieu Bourgey
    INSERM Unité 535, B P 1000, 94817 Villejuif Cedex, France
    BMC Genet 6:S87. 2005
  7. doi request reprint The ordered transmission disequilibrium test: detection of modifier genes
    Hervé Perdry
    INSERM U535, BP 1000, F 94817 Villejuif, France
    Genet Epidemiol 33:1-5. 2009
  8. doi request reprint Genetic association and gene-environment interaction: a new method for overcoming the lack of exposure information in controls
    Rémi Kazma
    Universite Paris Sud, Le Kremlin Bicetre, France
    Am J Epidemiol 173:225-35. 2011
  9. pmc Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium
    Rémi Kazma
    Universite Paris Sud, Villejuif, France
    Carcinogenesis 33:1059-64. 2012
  10. pmc Impact of the diagnosis definition on linkage detection
    Marie Hélène Dizier
    Hopital Paul Brousse, Bâtiment Leriche, B P 1000, 94817 Villejuif Cedex, France
    BMC Genet 6:S140. 2005

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Genetic interaction of CTLA-4 with HLA-DR15 in multiple sclerosis patients
    Mehdi Alizadeh
    Laboratoire Universitaire d Immunologie UPRES EA 1257, IFR 97 and Etablissement Français du Sang Bretagne, Faculte de Medecine, Rennes, France
    Ann Neurol 54:119-22. 2003
    ..Our data were obtained from two European independent family-based studies including 610 multiple sclerosis family trios. Ann Neurol 2003;54:119-122..
  2. ncbi request reprint Meta and pooled analysis of European coeliac disease data
    Marie Claude Babron
    1INSERM U535, Villejuif, France
    Eur J Hum Genet 11:828-34. 2003
    ..This region was suggested by several individual studies, but did not reach statistical values high enough to be conclusive when data sets were analysed separately...
  3. pmc An ordered subset approach to including covariates in the transmission disequilibrium test
    Hervé Perdry
    INSERM U535, BP 1000, Villejuif, 94817, France
    BMC Proc 1:S77. 2007
    ..For a third locus, detectable by the classical transmission-disequilibrium test, a substantial increase of power of detection is shown...
  4. pmc On the choice of linkage statistics
    Patricia Margaritte Jeannin
    INSERM U535, F 94817 Villejuif, France
    BMC Proc 1:S102. 2007
    ..In a second step, we show that performing the analysis under a greater number of genetic models in the hope of better scanning the space of models, does not increase the power of detection...
  5. pmc Detection of susceptibility loci by genome-wide linkage analysis
    Marie Claude Babron
    INSERM U535, 94817 Villejuif Cedex, Villejuif, France
    BMC Genet 6:S18. 2005
    ..Our results for the individual replicates are consistent with the disease model used in the simulation...
  6. pmc Modeling the effect of a genetic factor for a complex trait in a simulated population
    Mathieu Bourgey
    INSERM Unité 535, B P 1000, 94817 Villejuif Cedex, France
    BMC Genet 6:S87. 2005
    ..However, we could not find any model that could explain the familial segregation of the trait, namely the higher proportion of affected parents than affected sibs...
  7. doi request reprint The ordered transmission disequilibrium test: detection of modifier genes
    Hervé Perdry
    INSERM U535, BP 1000, F 94817 Villejuif, France
    Genet Epidemiol 33:1-5. 2009
    ..We investigate the power of the method by simulations under various genetic models and covariate distributions and compare it with a linear regression analysis...
  8. doi request reprint Genetic association and gene-environment interaction: a new method for overcoming the lack of exposure information in controls
    Rémi Kazma
    Universite Paris Sud, Le Kremlin Bicetre, France
    Am J Epidemiol 173:225-35. 2011
    ..Interestingly, it even has better power than the joint test requiring full knowledge of the environmental information in both cases and controls...
  9. pmc Lung cancer and DNA repair genes: multilevel association analysis from the International Lung Cancer Consortium
    Rémi Kazma
    Universite Paris Sud, Villejuif, France
    Carcinogenesis 33:1059-64. 2012
    ..This first international pooled analysis of a large dataset unravels the role of specific DNA repair pathways in LC and highlights the importance of accounting for gene and pathway effects when studying LC...
  10. pmc Impact of the diagnosis definition on linkage detection
    Marie Hélène Dizier
    Hopital Paul Brousse, Bâtiment Leriche, B P 1000, 94817 Villejuif Cedex, France
    BMC Genet 6:S140. 2005
    ..A genetic factor located on the chromosome 1 may have been detected here which would be involved specifically in traits a and b or in a combination of these traits...
  11. ncbi request reprint A novel locus for autosomal dominant "uncomplicated" hereditary spastic paraplegia maps to chromosome 8p21.1-q13.3
    Sylvain Hanein
    INSERM, Unit 679, 47 bd de l Hopital, 75013 Paris, France
    Hum Genet 122:261-73. 2007
    ..3-23.31, was found to segregate in all affected patients (but not in probably or possibly affected subjects) and in a high proportion of healthy at risk individuals, suggesting that this locus might act as a modifier of the phenotype...
  12. pmc Pleiotropic effects of CEP290 (NPHP6) mutations extend to Meckel syndrome
    Lekbir Baala
    Université René Descartes et INSERM U 781, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Am J Hum Genet 81:170-9. 2007
    ..These data identify a fourth locus for MKS (MKS4) and the CEP290 gene as responsible for MKS...
  13. ncbi request reprint Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study
    Margaret A Pericak-Vance
    Center for Human Genetics, Duke University Medical Center, Durham, North Carolina, USA
    Neurogenetics 5:45-8. 2004
    ..Regions on 1p34, 3p14, and 19q13 produced lod scores >0.90 in at least one subset of the data, suggesting that these regions should be examined in more detail...
  14. ncbi request reprint Genetic analysis of multiple sclerosis in Europeans: French data
    Mehdi Alizadeh
    Laboratoire d Immunologie, UPRES EA 1257 IFR97, Faculte de Medecine, 2 Avenue du Pr Léon Bernard CS 34317, 35043 Rennes Cedex, France
    J Neuroimmunol 143:74-8. 2003
    ..These potential associations will require confirmation in further studies...