E Azoulay

Summary

Country: France

Publications

  1. ncbi request reprint [Limiting life sustaining therapies]
    E Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris 7, France
    Rev Mal Respir 23:13S29-45. 2006
  2. pmc Ventilator-associated pneumonia and ICU mortality in severe ARDS patients ventilated according to a lung-protective strategy
    Jean Marie Forel
    Service de Réanimation des Détresses Respiratoires et Infections Sévères, Assistance Publique Hopitaux de Marseille, URMITE CNRS UMR 6236, Aix Marseille Univ, Marseille 13015, France
    Crit Care 16:R65. 2012
  3. pmc Symptoms of depression in ICU physicians
    Nathalie Embriaco
    Aix Marseille University, URMITE CNRS UMR 7278, 13005 Marseille, France APHM, Hopital Nord, Réanimation des détresses Respiratoires et des Infections sévères, 13015, Marseille, France
    Ann Intensive Care 2:34. 2012
  4. doi request reprint Noninvasive mechanical ventilation in patients having declined tracheal intubation
    Elie Azoulay
    Medical ICU, Saint Louis Hospital AP HP, Medical ICU, Faculte de Medecine, Universite Paris Diderot, Sorbonne Paris Cité, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 39:292-301. 2013
  5. doi request reprint Increased nonbeneficial care in patients spending their birthday in the ICU
    Elie Azoulay
    Medical ICU, AP HP, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 38:1169-76. 2012
  6. doi request reprint Dexamethasone in patients with acute lung injury from acute monocytic leukaemia
    E Azoulay
    Medical ICU, Saint Louis Hospital, Paris, France
    Eur Respir J 39:648-53. 2012
  7. pmc Evaluating mortality in intensive care units: contribution of competing risks analyses
    Matthieu Resche-Rigon
    Biostatistics Department, Saint Louis Teaching Hospital Assistance Publique Hôpitaux de Paris, 1 avenue Claude Vellefaux, Paris, 75010, France
    Crit Care 10:R5. 2006
  8. pmc Model for predicting short-term mortality of severe sepsis
    Christophe Adrie
    Medical Surgical Intensive Care Unit, Delafontaine Hospital, 93205 Saint Denis, France
    Crit Care 13:R72. 2009
  9. ncbi request reprint Is there a place for granulocyte colony-stimulating factor in non-neutropenic critically ill patients?
    Elie Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 30:10-7. 2004
  10. ncbi request reprint Pleural effusions in the intensive care unit
    Elie Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris, France
    Curr Opin Pulm Med 9:291-7. 2003

Detail Information

Publications118 found, 100 shown here

  1. ncbi request reprint [Limiting life sustaining therapies]
    E Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris 7, France
    Rev Mal Respir 23:13S29-45. 2006
    ..Intensivists are increasingly implementing end-of-life decisions in patients who remain dependent on life sustaining therapies without hope for recovery...
  2. pmc Ventilator-associated pneumonia and ICU mortality in severe ARDS patients ventilated according to a lung-protective strategy
    Jean Marie Forel
    Service de Réanimation des Détresses Respiratoires et Infections Sévères, Assistance Publique Hopitaux de Marseille, URMITE CNRS UMR 6236, Aix Marseille Univ, Marseille 13015, France
    Crit Care 16:R65. 2012
    ..We aimed to determine the incidence, outcome, and risk factors of bacterial VAP complicating severe ARDS in patients ventilated by using a strictly standardized lung-protective strategy...
  3. pmc Symptoms of depression in ICU physicians
    Nathalie Embriaco
    Aix Marseille University, URMITE CNRS UMR 7278, 13005 Marseille, France APHM, Hopital Nord, Réanimation des détresses Respiratoires et des Infections sévères, 13015, Marseille, France
    Ann Intensive Care 2:34. 2012
    ..abstract:..
  4. doi request reprint Noninvasive mechanical ventilation in patients having declined tracheal intubation
    Elie Azoulay
    Medical ICU, Saint Louis Hospital AP HP, Medical ICU, Faculte de Medecine, Universite Paris Diderot, Sorbonne Paris Cité, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 39:292-301. 2013
    ..The aim of our study was to report outcomes after NIV in patients with a do-not-intubate (DNI) order...
  5. doi request reprint Increased nonbeneficial care in patients spending their birthday in the ICU
    Elie Azoulay
    Medical ICU, AP HP, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 38:1169-76. 2012
    ..Previous studies identified substantial subjective biases during end-of-life decision-making. We evaluated whether in-ICU patient's birthday influenced management decisions...
  6. doi request reprint Dexamethasone in patients with acute lung injury from acute monocytic leukaemia
    E Azoulay
    Medical ICU, Saint Louis Hospital, Paris, France
    Eur Respir J 39:648-53. 2012
    ..These results warrant a controlled trial of dexamethasone versus placebo in AML FAB-M5 patients with noninfectious pulmonary infiltrates...
  7. pmc Evaluating mortality in intensive care units: contribution of competing risks analyses
    Matthieu Resche-Rigon
    Biostatistics Department, Saint Louis Teaching Hospital Assistance Publique Hôpitaux de Paris, 1 avenue Claude Vellefaux, Paris, 75010, France
    Crit Care 10:R5. 2006
    ..To address these issues, we exemplified the usefulness of standard competing risks methods; namely, cumulative incidence function (CIF) curves and the Fine and Gray model...
  8. pmc Model for predicting short-term mortality of severe sepsis
    Christophe Adrie
    Medical Surgical Intensive Care Unit, Delafontaine Hospital, 93205 Saint Denis, France
    Crit Care 13:R72. 2009
    ..To establish a prognostic model for predicting 14-day mortality in ICU patients with severe sepsis overall and according to place of infection acquisition and to sepsis episode number...
  9. ncbi request reprint Is there a place for granulocyte colony-stimulating factor in non-neutropenic critically ill patients?
    Elie Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 30:10-7. 2004
    ..This variability should be taken into account when designing studies on the use of G-CSF in ICU-patients. Studies are still needed to identify the subset of patients who may benefit from G-CSF therapy...
  10. ncbi request reprint Pleural effusions in the intensive care unit
    Elie Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris, France
    Curr Opin Pulm Med 9:291-7. 2003
    ..Lastly, the author suggests a research agenda for pleural effusions in intensive care unit patients...
  11. ncbi request reprint The prognosis of acute respiratory failure in critically ill cancer patients
    Elie Azoulay
    Medical Intensive Care Unit, Biostatistics Department, Saint Louis Hospital and Paris 7 University, Paris, France
    Medicine (Baltimore) 83:360-70. 2004
    ..The impact of conventional mechanical ventilation on survival depends on the time from ICU admission to conventional mechanical ventilation and on the patient's response to noninvasive mechanical ventilation...
  12. ncbi request reprint Acute monocytic leukemia presenting as acute respiratory failure
    Elie Azoulay
    Medical Intensive Care Unit, Hematology Department, Saint Louis Teaching Hospital, Paris 7 University, France
    Am J Respir Crit Care Med 167:1329-33. 2003
    ....
  13. ncbi request reprint Communication with family members of patients dying in the intensive care unit
    Elie Azoulay
    Service de Réanimation Médicale Hôpital Saint Louis, Paris, France
    Curr Opin Crit Care 9:545-50. 2003
    ..The need for family-centered care and for a better communication within the patient-family-caregiver trio is also highlighted...
  14. ncbi request reprint Practices in non-neutropenic ICU patients with Candida-positive airway specimens
    Elie Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 30:1384-9. 2004
    ..Design : Closed-item questionnaire with a clinical vignette...
  15. ncbi request reprint Diagnostic strategy in cancer patients with acute respiratory failure
    Elie Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris 7, Paris, France
    Intensive Care Med 32:808-22. 2006
    ..The most recent literature is reviewed, and emphasis is placed on current controversies, most notably the risk/benefit ratio of fiberoptic bronchoscopy and BAL in patients with severe hypoxemia...
  16. ncbi request reprint Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: prospective multicenter data
    Elie Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital, Paris, France
    Crit Care Med 36:100-7. 2008
    ..To describe the diagnostic yields of test strategies with and without fiberoptic bronchoscopy and bronchoalveolar lavage (FO-BAL), as well as outcomes, in cancer patients with acute respiratory failure (ARF)...
  17. ncbi request reprint [Diagnosis and management of pleural effusions in critically iII patients]
    E Azoulay
    Service de Reanimation Medicale, hôpital Saint Louis et Université Paris VII, Assistance Publique Hopitaux de Paris, Paris, France
    Rev Mal Respir 22:71-9. 2005
    ..Pleural effusions frequently complicate cardiac and abdominal surgery and haemothorax may complicate trauma...
  18. doi request reprint End-of-life practices in 282 intensive care units: data from the SAPS 3 database
    Elie Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris 7, Assistance Publique, Hopitaux de Paris, Paris, France
    Intensive Care Med 35:623-30. 2009
    ..To report incidence and characteristics of decisions to forgo life-sustaining therapies (DFLSTs) in the 282 ICUs who contributed to the SAPS3 database...
  19. ncbi request reprint Risk of post-traumatic stress symptoms in family members of intensive care unit patients
    Elie Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, Paris, France
    Am J Respir Crit Care Med 171:987-94. 2005
    ..Intensive care unit (ICU) admission of a relative is a stressful event that may cause symptoms of post-traumatic stress disorder (PTSD)...
  20. doi request reprint Polymerase chain reaction for diagnosing pneumocystis pneumonia in non-HIV immunocompromised patients with pulmonary infiltrates
    Elie Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, 1 avenue Claude Vellefaux, Paris, France
    Chest 135:655-61. 2009
    ..Pneumocystis jiroveci polymerase chain reaction (PCR) has higher sensitivity than conventional stains but cannot distinguish colonization from infection...
  21. doi request reprint Prevalence and factors of intensive care unit conflicts: the conflicus study
    Elie Azoulay
    AP HP, Hopital Saint Louis, Medical ICU, University Paris 7 Paris Diderot, UFR de Medecine, 1 avenue Claude Vellefaux, 75010 Paris, France
    Am J Respir Crit Care Med 180:853-60. 2009
    ..Many sources of conflict exist in intensive care units (ICUs). Few studies recorded the prevalence, characteristics, and risk factors for conflicts in ICUs...
  22. doi request reprint Palliative noninvasive ventilation in patients with acute respiratory failure
    Elie Azoulay
    Service de Reanimation Medicale, APHP, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 37:1250-7. 2011
    ....
  23. ncbi request reprint Infection as a trigger of diabetic ketoacidosis in intensive care-unit patients
    E Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital and Paris 7 University, Paris, France
    Clin Infect Dis 32:30-5. 2001
    ..73; CI, 1.58-9.09). Infection is the leading trigger of DKA in ICU patients. Neurological symptoms at admission and lack of complete clearance of ketonuria within 12 h are useful warning signals of infection...
  24. ncbi request reprint Family participation in care to the critically ill: opinions of families and staff
    Elie Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 29:1498-504. 2003
    ..Allowing family members to participate in the care of patients in intensive care units (ICUs) may improve the quality of their experience. No previous study has investigated opinions about family participation in ICUs...
  25. ncbi request reprint Predictors of short-term mortality in critically ill patients with solid malignancies
    E Azoulay
    Medical Intensive Care Unit, Saint Louis Teaching Hospital and University Paris 7, France
    Intensive Care Med 26:1817-23. 2000
    ....
  26. ncbi request reprint Meeting the needs of intensive care unit patient families: a multicenter study
    E Azoulay
    Intensive Care Department of the Saint Louis Teaching Hospital and Paris 7 University, Paris, France
    Am J Respir Crit Care Med 163:135-9. 2001
    ..Predictors of satisfaction are amenable to intervention and deserve to be investigated further with the goal of improving the satisfaction of ICU patients' family members...
  27. ncbi request reprint Rapid diagnosis of infectious pleural effusions by use of reagent strips
    E Azoulay
    Medical Intensive Care Unit, Saint Louis Teaching Hospital, Paris 7 University, France
    Clin Infect Dis 31:914-9. 2000
    ..Thus, reagent strips may be a rapid, easy-to-use, and inexpensive technique for discriminating transudative from exudative pleural effusions and for categorizing exudative pleural effusions as infectious or noninfectious...
  28. ncbi request reprint Improved survival in cancer patients requiring mechanical ventilatory support: impact of noninvasive mechanical ventilatory support
    E Azoulay
    Medical Intensive Care Unit, Saint Louis University Hospital and University Paris 7, France
    Crit Care Med 29:519-25. 2001
    ..However, recent studies have found that outcomes of critically ill cancer patients have been improving over the years and that classic predictors of high mortality have lost their relevance...
  29. ncbi request reprint Changing use of intensive care for hematological patients: the example of multiple myeloma
    E Azoulay
    Medical Intensive Care Unit, Saint Louis Teaching Hospital, Paris, France
    Intensive Care Med 25:1395-401. 1999
    ..This change mandates a reappraisal of indications for ICU admission in each type of hematological disease. Improved knowledge of the prognosis is of assistance in making treatment decisions...
  30. ncbi request reprint Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients: a multicenter, prospective, randomized, controlled trial
    Elie Azoulay
    Intensive Care Department, Saint Louis Teaching Hospital, Paris 7 University, France
    Am J Respir Crit Care Med 165:438-42. 2002
    ..01). These results indicate that ICU caregivers should consider using an FIL to improve the effectiveness of the information they impart to families...
  31. ncbi request reprint Symptoms of anxiety and depression in family members of intensive care unit patients: ethical hypothesis regarding decision-making capacity
    F Pochard
    , , Paris, France
    Crit Care Med 29:1893-7. 2001
    ..Involvement of anxious or depressed family members in end-of-life decisions should be carefully discussed...
  32. ncbi request reprint French intensivists do not apply American recommendations regarding decisions to forgo life-sustaining therapy
    F Pochard
    , , Paris, France
    Crit Care Med 29:1887-92. 2001
    ..In many cases, the decision was taken without regard for one or more factors identified as relevant in U.S. guidelines...
  33. doi request reprint Study of prone positioning to reduce ventilator-associated pneumonia in hypoxaemic patients
    R Mounier
    Assistance Publique Hopitaux de Paris, Louis Mourier Hospital, Medical ICU, Colombes, France
    Eur Respir J 35:795-804. 2010
    ..In ICU patients with hypoxaemic acute respiratory failure, PP had no effect on the risk of VAP. PP delayed mortality without decreasing 28-day mortality. PP >1 day might decrease mortality, particularly in the sickest patients...
  34. ncbi request reprint Accuracy of a composite score using daily SAPS II and LOD scores for predicting hospital mortality in ICU patients hospitalized for more than 72 h
    J F Timsit
    Réanimation des maladies infectieuses, Hĵpital Bichat Claude Bernard, Paris, France
    Intensive Care Med 27:1012-21. 2001
    ..Consequently, these scores are not the most appropriate tools for measuring prognosis in studies dealing with ICU patients hospitalized for more than 72 h...
  35. ncbi request reprint Routine exploratory thoracentesis in ICU patients with pleural effusions: results of a French questionnaire study
    E Azoulay
    Medical Intensive Care Unit, Saint Louis Hospital, Paris, France
    J Crit Care 16:98-101. 2001
    ..This may be due to the lack of precise guidelines on the topic and prompt the design of further studies to establish precisely the epidemiology and causes of pleural effusions in ICU patients...
  36. ncbi request reprint Delayed treatment contributes to mortality in ICU patients with severe active pulmonary tuberculosis and acute respiratory failure
    J R Zahar
    Intensive Care Department, Bichat Claude Bernard Hospital, University Paris 7, 46 rue Henri Huchard, 75018 Paris, France
    Intensive Care Med 27:513-20. 2001
    ..To clarify the patterns of pulmonary tuberculosis (TB) that should result in a high index of suspicion, to increase the chances of early therapy and to identify predictors of 30-day mortality...
  37. doi request reprint Do hypooncotic fluids for shock increase the risk of late-onset acute respiratory distress syndrome?
    Frederique Schortgen
    Service de Reanimation Medicale, AP HP, Groupe Hospitalier Albert Chenevier Henri Mondor, Creteil 94000, France
    Intensive Care Med 36:1724-34. 2010
    ..PARTICIPANT AND SETTINGS: International prospective cohort of consecutive adults who were free of ARDS on admission and who received fluid resuscitation for shock in 115 intensive care units (ICUs) during a 4-week period...
  38. doi request reprint Assessing burden in families of critical care patients
    Nancy Kentish-Barnes
    Medical Intensive Care Unit Department, AP HP, Hopital Saint Louis, Paris, France
    Crit Care Med 37:S448-56. 2009
    ..To provide critical care clinicians with information on validated instruments for assessing burden in families of critical care patients...
  39. doi request reprint Significance of herpesvirus 6 in BAL fluid of hematology patients with acute respiratory failure
    E Mariotte
    Medical ICU, Hopital Saint Louis, Assistance Publique Hopitaux de Paris, 1 avenue Claude Vellefaux, Paris, France
    Infection 39:225-30. 2011
    ..However, the clinical significance of a positive PCR test for HHV6 in respiratory samples from patients with hematological malignancies remains unclear...
  40. ncbi request reprint Respiratory status deterioration during G-CSF-induced neutropenia recovery
    L Karlin
    1Medical Intensive Care Unit, Saint Louis Teaching Hospital and Paris 7 University, Assistance Publique, Hopitaux de Paris, Paris, France
    Bone Marrow Transplant 36:245-50. 2005
    ....
  41. ncbi request reprint Family-physician interactions in the intensive care unit
    Elie Azoulay
    Medical ICU, Saint Louis Teaching Hospital, and Paris 7 University Paris, France
    Crit Care Med 32:2323-8. 2004
    ....
  42. ncbi request reprint Half the family members of intensive care unit patients do not want to share in the decision-making process: a study in 78 French intensive care units
    Elie Azoulay
    Intensive Care Unit of the Saint Louis Teaching Hospital and University of Paris 7, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 32:1832-8. 2004
    ....
  43. ncbi request reprint Compliance with triage to intensive care recommendations
    E Azoulay
    Intensive Care and Biostatistics Departments, Saint-Louis Teaching Hospital and Paris VII Teaching, Paris, France
    Crit Care Med 29:2132-6. 2001
    ..These recommendations may need to be redesigned to improve their practicability under real-life conditions, with special attention to phone triage and triaging to a full unit...
  44. doi request reprint Case volume and mortality in haematological patients with acute respiratory failure
    L Lecuyer
    Intensive Care Unit and Biostatistics Dept, Saint Louis Teaching Hospital, Paris, France
    Eur Respir J 32:748-54. 2008
    ..The mechanisms of the relationship between volume and outcome among haematological patients with acute respiratory deserve additional studies...
  45. ncbi request reprint Outcome of critically ill allogeneic hematopoietic stem-cell transplantation recipients: a reappraisal of indications for organ failure supports
    Frédéric Pène
    Medical Intensive Care Unit, Cochin Hospital, AP HP, Paris, France
    J Clin Oncol 24:643-9. 2006
    ....
  46. doi request reprint Predictors of noninvasive ventilation failure in patients with hematologic malignancy and acute respiratory failure
    Mélanie Adda
    AP HP, Hopital Saint Louis, Medical ICU, Paris, France
    Crit Care Med 36:2766-72. 2008
    ..However, failure of noninvasive ventilation may lead to an increased mortality...
  47. ncbi request reprint One-day quantitative cross-sectional study of family information time in 90 intensive care units in France
    Thomas Fassier
    Intensive Care Unit of the Saint Louis Teaching Hospital and University of Paris 7, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 35:177-83. 2007
    ..Time spent informing families has been associated with effectiveness of information but has not been measured in specifically designed studies...
  48. ncbi request reprint Decisions to forgo life-sustaining therapy in ICU patients independently predict hospital death
    Elie Azoulay
    Saint Louis Teaching Hospital, Medical ICU Department, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 29:1895-901. 2003
    ..The objectives of this study were to describe the factors and mortality associated with DFLSTs and to evaluate the potential independent impact of DFLSTs on hospital mortality...
  49. ncbi request reprint Tracheostomy does not improve the outcome of patients requiring prolonged mechanical ventilation: a propensity analysis
    Christophe Clec'h
    Intensive Care Unit, Avicenne Teaching Hospital, 125 route de Stalingrad, 93000 Bobigny, France
    Crit Care Med 35:132-8. 2007
    ..To examine the association between the performance of a tracheostomy and intensive care unit and postintensive care unit mortality, controlling for treatment selection bias and confounding variables...
  50. ncbi request reprint [Diagnostic strategy for acute respiratory failure in patients with haematological malignancy]
    E Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, Universite Paris Diderot, Assistance Publique Hopitaux de Paris, 1 avenue Claude Vellefaux, Paris, France
    Rev Mal Respir 25:433-49. 2008
    ..About 15% of patients with haematological malignancy develop acute respiratory failure (ARF), necessitating admission to intensive care where their mortality is of the order of 50%...
  51. ncbi request reprint AIDS-related Pneumocystis carinii pneumonia in the era of adjunctive steroids: implication of BAL neutrophilia
    E Azoulay
    Service de Pneumologie et Reanimation Respiratoire, Unité de Biostatistique, INSERM U444, France Hôpital Tenon, Paris, France
    Am J Respir Crit Care Med 160:493-9. 1999
    ..In the era of adjunctive steroid use, AIDS-related PCP remains fairly common. Two independent factors evaluable at admission, Pa(O(2)) on room air and BAL neutrophilia, are predictive of death...
  52. ncbi request reprint The ICU trial: a new admission policy for cancer patients requiring mechanical ventilation
    Lucien Lecuyer
    AP HP, Saint Louis Hospital, Medical ICU, Paris 7 University, Paris, France
    Crit Care Med 35:808-14. 2007
    ..Cancer patients requiring mechanical ventilation are widely viewed as poor candidates for intensive care unit (ICU) admission. We designed a prospective study evaluating a new admission policy titled The ICU Trial...
  53. ncbi request reprint A communication strategy and brochure for relatives of patients dying in the ICU
    Alexandre Lautrette
    Saint Louis Hospital and Paris 7 University, Assistance Publique Hopitaux de Paris, France
    N Engl J Med 356:469-78. 2007
    ..We evaluated a format that included a proactive end-of-life conference and a brochure to see whether it could lessen the effects of bereavement...
  54. doi request reprint Functional outcome after convulsive status epilepticus
    Stephane Legriel
    Intensive Care Department, Centre Hospitalier de Versailles, André Mignot Hospital, Le Chesnay, France
    Crit Care Med 38:2295-303. 2010
    ..Few outcome data are available about convulsive status epilepticus managed in the intensive care unit. We studied 90-day functional outcomes and their determinants in patients with convulsive status epilepticus...
  55. ncbi request reprint Sedation, sucralfate, and antibiotic use are potential means for protection against early-onset ventilator-associated pneumonia
    C Bornstain
    Medical ICU, Saint Louis Hospital, 75010 Paris, France
    Clin Infect Dis 38:1401-8. 2004
    ..33; 95% CI, 0.16-0.74). Sucralfate use and unplanned extubation are independent risk factors for EOP. Use of aminoglycosides, beta-lactams/ beta-lactamase inhibitors, or third-generation cephalosporins protects against EOP...
  56. ncbi request reprint Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU stays
    Delphine Moreau
    Medical ICU, Saint Louis Teaching Hospital, 1 Ave Claude Vellefaux, 75010 Paris, France
    Chest 131:1735-41. 2007
    ..Thrombocytopenia is common in ICU patients. The objective of this study was to evaluate possible links between declining platelet counts early in the ICU stay and survival...
  57. doi request reprint Diagnostic strategy for hematology and oncology patients with acute respiratory failure: randomized controlled trial
    Elie Azoulay
    Medical Intensive Care Unit, Saint Louis Teaching Hospital, 75010 Paris, France
    Am J Respir Crit Care Med 182:1038-46. 2010
    ..Fiberoptic bronchoscopy with bronchoalveolar lavage (FO-BAL) is an invasive test that may cause respiratory deterioration. Recent noninvasive diagnostic tests may have modified the risk/benefit ratio of FO-BAL...
  58. ncbi request reprint Impact of neutropenia duration on short-term mortality in neutropenic critically ill cancer patients
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital and Paris 7 University, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 28:1775-80. 2002
    ..To identify predictors of 30-day mortality and to assess the impact of neutropenia recovery (NR) on 30-day mortality in critically ill cancer patients (CICPs)...
  59. doi request reprint Real-time PCR assay-based strategy for differentiation between active Pneumocystis jirovecii pneumonia and colonization in immunocompromised patients
    A Alanio
    Laboratory of Parasitology Mycology, Saint Louis Hospital, Assistance Publique Hôpitaux de Paris and Université Paris Diderot, Paris, France
    Clin Microbiol Infect 17:1531-7. 2011
    ..This is particularly relevant for patient management, especially in non-human immunodeficiency virus (HIV)-infected immunocompromised patients, who often present low-burden P. jirovecii infections that are not diagnosed microscopically...
  60. ncbi request reprint Junior versus senior physicians for informing families of intensive care unit patients
    Delphine Moreau
    Service de Reanimation Medicale, Hopital Saint Louis, Paris, France
    Am J Respir Crit Care Med 169:512-7. 2004
    ..9 vs. 34.4%, p = 0.004). Specialty residents, if given opportunities for acquiring experience, can become proficient in communicating with families and share this task with senior physicians...
  61. ncbi request reprint Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial
    Djillali Annane
    Raymond Poincaré Hospital AP HP, University of Versailles Saint Quentin, PRES UniverSud, Paris, France
    Lancet 370:676-84. 2007
    ..However, no large comparative trial has yet been done. We aimed to compare the efficacy and safety of norepinephrine plus dobutamine (whenever needed) with those of epinephrine alone in septic shock...
  62. ncbi request reprint Pneumothorax in the intensive care unit: incidence, risk factors, and outcome
    Arnaud de Lassence
    Medical Intensive Care Unit, Assistance Publique Hopitaux de Paris, Louis Mourier Teaching Hospital, Colombes, France
    Anesthesiology 104:5-13. 2006
    ..The risk factors and outcomes of critically ill patients with iatrogenic pneumothorax (IP) have not been studied in a large unselected intensive care unit (ICU) population...
  63. doi request reprint Prognostic significance of acute renal injury in acute tumor lysis syndrome
    Michael Darmon
    Assistance Publique des Hopitaux de Paris, Medical Intensive Care Unit, Saint Louis University Hospital, Paris, France
    Leuk Lymphoma 51:221-7. 2010
    ..64-54.66; p = 0.006), compared to patients without renal injury. Our study suggests that in patients with ATLS, ICU management when acute renal injury is present is associated with higher short- and long-term mortality...
  64. ncbi request reprint Care at the end of life in critically ill patients: the European perspective
    Thomas Fassier
    Medical Intensive Care Unit, Saint Louis Teaching Hospital and Paris 7 University, Paris, France
    Curr Opin Crit Care 11:616-23. 2005
    ..The aim of this review is to provide insight into the decisions to forego life sustaining therapies and end-of-life care in Europe...
  65. ncbi request reprint Effectiveness of platelet transfusions after plasma exchange in adult thrombotic thrombocytopenic purpura: a report of two cases
    P Coppo
    Service d immuno hématologie, Hôpital Saint Louis et Université, Paris, France
    Am J Hematol 68:198-201. 2001
    ..Am. J. Hematol. 68:198-201, 2001. Published 2001 Wiley-Liss, Inc...
  66. ncbi request reprint [Pulmonary legionellosis at the earliest stage of hairy cell leukemia]
    M Harandou
    Service de Reanimation Medicale, Hopital Saint Louis, 1, avenue Claude Vellefaux, 75010 Paris
    Rev Pneumol Clin 61:258-60. 2005
    ..Serology provided the diagnosis and the patient improved with adequate treatment. Early diagnosis and appropriate treatment may reduce the mortality of this serious complication...
  67. ncbi request reprint Diagnostic contribution from pulmonary biopsies in hematology patients with acute respiratory failure from undetermined etiology
    J Gay
    Medical Intensive Care, Saint Louis Hospital, Paris, France
    Minerva Anestesiol 79:853-60. 2013
    ..Conclusion: Diagnostic lung biopsy is rarely needed in hematology patients with ARF. But, it has a 73% therapeutic impact and has overall no major complications. Contribution from post-mortem biopsies seems less relevant. ..
  68. ncbi request reprint Inflammatory response to infectious pulmonary injury
    C Delclaux
    Service de Physiologie Explorations Fonctionnelles, Hopital Henri Mondor, Assistance Publique, Hopitaux de Paris AP HP, Creteil, France
    Eur Respir J Suppl 42:10s-14s. 2003
    ..The soluble factors in innate defence, such as cytokines, are described, and a last paragraph discusses whether a specific inflammatory response could characterise nosocomial pneumonia...
  69. doi request reprint The risk associated with hyperoncotic colloids in patients with shock
    Frederique Schortgen
    Réanimation Médicale, AP HP, Groupe Hospitalier Albert Chenevier, Henri Mondor, 94000 Creteil, France
    Intensive Care Med 34:2157-68. 2008
    ..This study assessed the risk of renal adverse events in patients with shock resuscitated using hypo-oncotic colloids, artificial hyperoncotic colloids, hyperoncotic albumin or crystalloids, according to physician's choice...
  70. ncbi request reprint Pneumocystis carinii pneumonia in critically ill patients with malignancy: a descriptive study
    J R Zahar
    Intensive Care Department, Institut Gustave Roussy, Paris, France
    Clin Infect Dis 35:929-34. 2002
    ..9). Studies are needed to determine whether aggressive monitoring and treatment of patients with >15% neutrophils in BAL fluid specimens can improve the outcome of critically ill patients with malignancy and PCP...
  71. ncbi request reprint Outcome of cancer patients considered for intensive care unit admission: a hospital-wide prospective study
    Guillaume Thiery
    Medical Intensive Care Unit, Saint Louis Teaching Hospital, 1 rue Claude Vellefaux, 75010 Paris, France
    J Clin Oncol 23:4406-13. 2005
    ..To evaluate the outcome of cancer patients considered for admission to the intensive care unit (ICU)...
  72. doi request reprint Impact of adverse events on outcomes in intensive care unit patients
    Maite Garrouste Orgeas
    Medical Surgical ICU, Saint Joseph Hospital Network, Paris, France
    Crit Care Med 36:2041-7. 2008
    ..To examine the association between predefined adverse events (AE) (including nosocomial infections) and intensive care unit (ICU) mortality, controlling for multiple adverse events in the same patient and confounding variables...
  73. doi request reprint Continued survival gains in recent years among critically ill myeloma patients
    Vincent Peigne
    Medical ICU, AP HP, Hopital Saint Louis, Paris, France
    Intensive Care Med 35:512-8. 2009
    ..Therapeutic advances have improved survival in patients with myeloma (MM) over the past decade. We investigated whether survival has also improved in critically ill myeloma patients...
  74. doi request reprint Qualitative research: adding drive and dimension to clinical research
    Katerina Rusinová
    FAMIREA Study Group, Assistance Publique Hopitaux de Paris, Saint Louis Teaching Hospital, Medical Intensive Care Unit, Paris, France
    Crit Care Med 37:S140-6. 2009
    ..To illustrate the effectiveness of combining different research methods, we will refer to recent qualitative studies conducted in the intensive care unit...
  75. ncbi request reprint Should dialysis be offered to cancer patients with acute kidney injury?
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital, Assistance Publique des Hôpitaux de Paris and Paris VII University, 1 av Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 33:765-72. 2007
    ....
  76. ncbi request reprint Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
    Djillali Annane
    Service de Reanimation Medicale, Hopital Raymond Poincare, 104 Blvd Raymond Poincaré, 92380 Garches, France
    JAMA 288:862-71. 2002
    ..Septic shock may be associated with relative adrenal insufficiency. Thus, a replacement therapy of low doses of corticosteroids has been proposed to treat septic shock...
  77. doi request reprint Association between hypernatraemia acquired in the ICU and mortality: a cohort study
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital, APHP, 1 avenue Claude Vellefaux, Paris, France
    Nephrol Dial Transplant 25:2510-5. 2010
    ..The aim of this study is to describe the prevalence and outcomes of intensive care unit (ICU)-acquired hypernatraemia (IAH)...
  78. ncbi request reprint Thrombotic microangiopathy with acquired deficiency in ADAMTS 13 activity in lung transplant recipients
    Herve Mal
    Groupe de transplantation pulmonaire, Hopital Beaujon, Assistance Publique Hx de Paris, Clichy, France
    Transplantation 81:1628-32. 2006
    ..Thrombotic microangiopathy may develop after solid organ transplantation, but it is usually not associated with severe deficiency in von Willebrand factor-cleaving metalloprotease (ADAMTS 13) activity...
  79. ncbi request reprint High level of burnout in intensivists: prevalence and associated factors
    Nathalie Embriaco
    Medical Intensive Care Unit, Hôpital Sainte Marguerite Teaching Hospital, Universite de la Mediterranee, Marseille 13009, France
    Am J Respir Crit Care Med 175:686-92. 2007
    ..Professional burnout is a psychological syndrome arising in response to chronic interpersonal stressors on the job. There is the perception that intensivists are particularly exposed to stress because lives are literally in their hands...
  80. pmc Clinical review: specific aspects of acute renal failure in cancer patients
    Michael Darmon
    Assistance Publique des Hopitaux de Paris, Saint Louis University Hospital, Medical ICU, Paris, France
    Crit Care 10:211. 2006
    ....
  81. ncbi request reprint Time course of organ dysfunction in thrombotic microangiopathy patients receiving either plasma perfusion or plasma exchange
    Michael Darmon
    Medical Intensive Care Unit, Assistance Publique Hopitaux de Paris, Saint Louis University Hospital, Paris, France
    Crit Care Med 34:2127-33. 2006
    ..Few studies have investigated adults with thrombotic microangiopathy (TMA) requiring intensive care unit (ICU) admission, and the treatment remains controversial...
  82. ncbi request reprint End-of-life family conferences: rooted in the evidence
    Alexandre Lautrette
    FAMIREA Study Group, Medical Intensive Care Unit, AP HP, Saint Louis Teaching Hospital and Paris 7 University, France
    Crit Care Med 34:S364-72. 2006
    ..Means of improving end-of-life care have been identified in epidemiologic and interventional studies. End-of-life family conferences constitute the keystone around which excellent end-of-life care can be built...
  83. doi request reprint Risk factors for pneumonia in immunocompromised patients with influenza
    David Schnell
    AP HP, Hopital Saint Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France
    Respir Med 104:1050-6. 2010
    ..Immunocompromised patients with influenza are at higher risk of pneumonia and death. However, risk factors for progression to pneumonia still need evaluation...
  84. ncbi request reprint Burnout syndrome in critical care nursing staff
    Marie Cecile Poncet
    Medical ICU, Saint Louis Hospital and Paris 7 University, Assistance Publique, Hopitaux de Paris, Paris, France
    Am J Respir Crit Care Med 175:698-704. 2007
    ..Burnout syndrome (BOS) associated with stress has been documented in health care professionals in many specialties. The intensive care unit (ICU) is a highly stressful environment. Little is known about BOS in critical care nursing staff...
  85. ncbi request reprint Clinically documented pleural effusions in medical ICU patients: how useful is routine thoracentesis?
    Muriel Fartoukh
    Medical and Respiratory Intensive Care Unit, Antoine Béclère Teaching Hospital, Paris, France
    Chest 121:178-84. 2002
    ..To assess the impact of routine thoracentesis on diagnostic assessment and therapeutic measures in patients with clinically documented pleural effusions...
  86. ncbi request reprint Improved survival of critically ill cancer patients with septic shock
    Jérôme Larché
    Medical ICU of the Saint Louis Teaching Hospital and Paris 7 University, Assistance Publique Hopitaux de Paris, 1 av Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 29:1688-95. 2003
    ..To identify predictors of 30-day mortality in critically ill cancer patients with septic shock...
  87. ncbi request reprint Year in review in intensive care medicine, 2004. I. Respiratory failure, infection, and sepsis
    Peter Andrews
    Medical Intensive Care Unit, University Hospital Henri Mondor, 51 Avenue du Marechal de Lattre de Tassigny, 94000 Creteil, France
    Intensive Care Med 31:28-40. 2005
  88. doi request reprint Surrogate decision makers for incompetent ICU patients: a European perspective
    Alexandre Lautrette
    Services de Réanimation Médicale, Hopital Saint Louis, Paris, France
    Curr Opin Crit Care 14:714-9. 2008
    ..Even though legitimacy of surrogates is now recognized by physicians, patients' management must take into account new legislations emphasizing patients' autonomy all over Europe...
  89. doi request reprint Central neurological complications in critically ill patients with malignancies
    Stephane Legriel
    Medical Intensive Care Unit, AP HP, Hopital Saint Louis, 75010 Paris, France
    Intensive Care Med 36:232-40. 2010
    ..To determine outcomes in critically ill patients hospitalized in the ICU for central neurological complications of cancer...
  90. ncbi request reprint Opinions about surrogate designation: a population survey in France
    Elie Azoulay
    The French Famirea Study Group, Intensive Care Unit of the Saint Louis Teaching Hospital, University Paris 7, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 31:1711-4. 2003
    ..The objective of this study was to determine whether people who are not yet ill are ready to accept surrogate designation. Attitudes toward family participation in care were explored also...
  91. doi request reprint Use of N-terminal pro-brain natriuretic peptide to detect cardiac origin in critically ill cancer patients with acute respiratory failure
    Aurélie Lefebvre
    Service de Reanimation Medicale, Hopital Saint Louis, AP HP, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 34:833-9. 2008
    ..To assess the accuracy of plasma N-terminal-pro-B-type natriuretic peptide concentrations (NT-proBNP) as a diagnostic tool to recognize acute respiratory failure (ARF) of cardiac origin...
  92. ncbi request reprint Intensive care in patients with newly diagnosed malignancies and a need for cancer chemotherapy
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital and Paris 7 University, France
    Crit Care Med 33:2488-93. 2005
    ..Patients with newly diagnosed cancer responsible for organ failures may require intensive care unit (ICU) admission and immediate chemotherapy. Outcomes in this population have not been studied...
  93. ncbi request reprint Palivizumab treatment of respiratory syncytial virus infection after allogeneic hematopoietic stem cell transplantation
    Flore Sicre de Fontbrune
    Hematologie Greffe, Universite Paris 7, Assistance Publique Hopitaux de Paris, Hopital Saint Louis, Paris, France
    Clin Infect Dis 45:1019-24. 2007
    ..Palivizumab did not prevent progression to lower respiratory infection and had no impact on the overall survival rate...
  94. doi request reprint Critical care management of cancer patients: cause for optimism and need for objectivity
    Michael Darmon
    Medical ICU, Saint Louis University Hospital, APHP, Paris, France
    Curr Opin Oncol 21:318-26. 2009
    ..This review discusses current outcomes of critically ill cancer patients and recent insights into prognostic factors. Persistent areas of uncertainty are emphasized...
  95. ncbi request reprint Impact of unplanned extubation and reintubation after weaning on nosocomial pneumonia risk in the intensive care unit: a prospective multicenter study
    Arnaud de Lassence
    Medical ICU, Avicenne Hospital, Bobigny, France
    Anesthesiology 97:148-56. 2002
    ....
  96. ncbi request reprint Ability of family members to predict patient's consent to critical care research
    Magali Ciroldi
    Medical Intensive Care Unit, AP HP, Saint Louis Teaching Hospital, Paris 7 University, Paris, France
    Intensive Care Med 33:807-13. 2007
    ..The accuracy with which surrogates consent to research on behalf of patients has not been evaluated in the intensive care unit (ICU)...
  97. ncbi request reprint Candida colonization of the respiratory tract and subsequent pseudomonas ventilator-associated pneumonia
    Elie Azoulay
    Medical ICU, Saint Louis Teaching Hospital, 1 Ave Claude Vellefaux, 75010 Paris, France
    Chest 129:110-7. 2006
    ..However, interactions between Candida and bacteria, particularly Pseudomonas, have been reported. Thus, Candida colonization of the respiratory tract may predispose to bacterial ventilator-associated pneumonia (VAP)...
  98. ncbi request reprint Post-ICU mortality in critically ill infected patients: an international study
    Elie Azoulay
    Intensive Care Unit, Saint Louis Hospital, Paris 7 University, 1 Avenue Claude, Vellefaux, 75010 Paris, France
    Intensive Care Med 31:56-63. 2005
    ..To determine the incidence and risk factors for post-ICU mortality in patients with infection...
  99. doi request reprint Human immunodeficiency virus-associated thrombotic microangiopathies: clinical characteristics and outcome according to ADAMTS13 activity
    S Malak
    Service d Hématologie et de Thérapie Cellulaire, AP HP, Hôpital Saint Antoine and UPMC Université Paris 06, Paris, France
    Scand J Immunol 68:337-44. 2008
    ..04). In conclusion, HIV-associated TMA with severe ADAMTS13 deficiency have less AIDS-related complications and a higher CD4(+) T cell count. TMA prognosis is better and comparable to this of idiopathic forms...
  100. ncbi request reprint Kidney biopsy in the critically ill patient, results of a multicentre retrospective case series
    C Philipponnet
    Service de Reanimation Medicale, Hopital Gabriel Montpied, CHU de Clermont Ferrand, F 63003, Clermont Université d Auvergne, Clermont Ferrand, France
    Minerva Anestesiol 79:53-61. 2013
    ..The impact of a contributive result of kidney biopsy on the management of patients in the intensive care unit (ICU) has not been extensively investigated yet...
  101. ncbi request reprint Year in review in intensive care medicine. 2005. I. Acute respiratory failure and acute lung injury, ventilation, hemodynamics, education, renal failure
    Peter Andrews
    Intensive Care Medicine Unit, Western General Hospital, Edinburgh, UK
    Intensive Care Med 32:207-16. 2006