Research Topics
| Jean Michel AzorinSummaryCountry: France Publications
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Publications
[Management of patients with acute manic or mixed episodes and outcome at three months]J M Azorin
SHU, psychiatrie adulte, CHU Sainte Marguerite, Marseille, France
Encephale 36:226-35. 2010..The long-term evaluation of the French EMBLEM cohort - 12, 24 months and up to five years - is presently ongoing...
Effect of asenapine on manic and depressive symptoms in bipolar I patients with mixed episodes: results from post hoc analysesJ M Azorin
Hospital Ste Marguerite, 270 Bd Sainte Marguerite, 13274 Marseille, France
J Affect Disord 145:62-9. 2013..The efficacy of agents useful for mania is largely unproven in patients with mixed episodes...
[Bipolar disorder: inter-episode symptoms]J M Azorin
PU PH, SHU Psychiatrie Adultes, Hopital Sainte Marguerite, 270 Bd Sainte Marguerite, Marseille Cedex 09
Encephale 38:S147-50. 2012..Residual symptoms, prodromes as well as other inter-episode symptoms may respond to strategies based on cognitive-behaviour therapy, and/or psychoeducation...
[Temperamental endophenotypes]J M Azorin
SHU Psychiatrie Adultes Pavillon Solaris, Hopital Sainte Marguerite, 13274 Marseille Cedex 09, France
Encephale 38:S70-4. 2012..Finally recent studies confirmed as well, that the concept of affective temperament fulfilled the criteria required to be considered as an endophenotype...
Self-assessment and characteristics of mixed depression in the French national EPIDEP studyJean Michel Azorin
Department of Psychiatry, Sainte Marguerite Hospital, Marseilles 13274, France Electronic address
J Affect Disord 143:109-17. 2012..Studies on mixed depression have been conducted so far on the basis of DSM-IV manic symptoms, i.e., a list of 7 symptoms which may provide limited information on the subsyndromal features associated with a full depressive episode...
Baseline and prodromal characteristics of first- versus multiple-episode mania in a French cohort of bipolar patientsJ M Azorin
SHU Psychiatrie Adultes, Hopital Sainte Marguerite, Assistance Publique Hopitaux de Marseille, 13274 Marseille Cedex 9, France
Eur Psychiatry 27:557-62. 2012..To identify some of the main features of bipolar disorder for both first-episode (FE) mania and the preceding prodromal phase, in order to increase earlier recognition...
Late-onset bipolar illness: the geriatric bipolar type VIJean Michel Azorin
Pôle Universitaire de Psychiatrie Solaris, Hopital Sainte Marguerite, Cedex, France
CNS Neurosci Ther 18:208-13. 2012..More studies are also needed to better disentangle the effects of age at onset from those of age itself...
Identifying features of bipolarity in patients with first-episode postpartum depression: findings from the international BRIDGE studyJean Michel Azorin
Department of Psychiatry, Sainte Marguerite Hospital, Marseille, France
J Affect Disord 136:710-5. 2012..The aims of this study were to assess rates of bipolar spectrum disorders in women experiencing their first episode of postpartum depression, and to find out features indicative of bipolarity in these patients...
[Major depression: features indicative of bipolarity?]J M Azorin
Pôle universitaire de psychiatrie hôpital Ste Marguerite, 270 Bd Sainte Marguerite, 13274 Marseille Cedex 09, France
Encephale 37:S163-8. 2011..Screening instruments may also be used, to facilitate early recognition. Validation studies of these diagnostic features and instruments are underway...
Psychopathological correlates of lifetime anxiety comorbidity in bipolar I patients: findings from a French national cohortJean Michel Azorin
Sainte Marguerite Hospital, University of Marseilles, Marseilles, France
Psychopathology 42:380-6. 2009..Despite numerous studies on the comorbidity of bipolar and anxiety disorders, there is no satisfactory psychopathological model for their overlap...
Suicidal behaviour in a French Cohort of major depressive patients: characteristics of attempters and nonattemptersJ M Azorin
Hopital Sainte Marguerite, Marseille, France
J Affect Disord 123:87-94. 2010..Identification of risk factors is therefore essential to prevent suicide in this population...
Toward the delineation of mania subtypes in the French National EPIMAN-II Mille Cohort. Comparisons with prior cluster analytic investigationsJean Michel Azorin
Adult Psychiatry Department, Ste Marguerite Hospital, 270 Bd Sainte Marguerite, 13274 Marseille Cedex 09, France
Eur Arch Psychiatry Clin Neurosci 258:497-504. 2008..Knowledge about psychopathologic presentations of mania in current clinical practice has to be refined in order to improve diagnosis and treatment...
Risk factors associated with lifetime suicide attempts in bipolar I patients: findings from a French National CohortJean Michel Azorin
Department of Psychiatry, Sainte Marguerite Hospital, Marseille, France
Compr Psychiatry 50:115-20. 2009..We finally propose to integrate such characteristics into a stress-diathesis model of suicidal behavior, adapted to bipolar patients...
[Who is Called "Schizophrenic"?]Jean Michel Azorin
pôle universitaire de psychiatrie, Hopital Sainte Marguerite, Marseille, France
Therapie 63:231-5. 2008..Taking these approaches into account, at a time when naturalistic models of the illness are prevailing, is far from being of no consequence, as far as the effectiveness of our therapeutic actions is at issue...
Factors associated with rapid cycling in bipolar I manic patients: findings from a French national studyJean Michel Azorin
University of Aix Marseille II, and Department of Adult Psychiatry, Sainte Marguerite Hospital, Marseille Cedex 09, France
CNS Spectr 13:780-7. 2008..Despite numerous explanatory hypotheses, few studies have involved a large national clinical sample examining risk factors in the occurrence of rapid cycling during the course of bipolar illness...
An update on the treatment of bipolar depressionJean Michel Azorin
Pôle Universitaire de Psychiatrie Solaris, Hopital Ste Marguerite, 13274 Marseille Cedex 9, France
Expert Opin Pharmacother 10:161-72. 2009..Although depression accounts for a large part of the burden associated with bipolar disorder, its drug treatment has been under-studied...
Validation of a severity threshold for the Mania Rating Scale: a receiver-operating characteristic analysisJean Michel Azorin
Sainte Marguerite Hospital, University of Marseilles, Marseilles, France
Psychopathology 40:453-60. 2007..The aim of this study was to determine a cutoff score on the Mania Rating Scale (MRS), which easily allows identification of severe mania in a population of manic patients to be included in clinical trials of antimanic drugs...
"Folie circulaire" vs "Folie à double forme": contribution from a French national studyJ M Azorin
SHU Psychiatrie Adultes, Sainte Marguerite Hospital, University of Marseille, 13274 Marseille Cedex 9, France
Eur Psychiatry 26:375-80. 2011..To check whether the presence or not of free intervals between episodes could help differentiate subtypes of bipolar disorder, as suggested by the seminal controversy between Falret and Baillarger...
Correlates of first-episode polarity in a French cohort of 1089 bipolar I disorder patients: role of temperaments and triggering eventsJean Michel Azorin
Department of Psychiatry, Sainte Marguerite Hospital, Marseilles, France
J Affect Disord 129:39-46. 2011....
Schizophrenia: two-faced meaning of vulnerabilityJean Michel Azorin
Department of Psychiatry, Ste Marguerite Hospital, Marseille, France
Am J Med Genet 114:921-2. 2002..Coping strategies and resilience are core concepts of the humanistic model. Research on these protective factors may be of major importance in the current debate on prevention in schizophrenia...
Sertindole for the treatment of schizophreniaJean Michel Azorin
Pôle Universitaire de Psychiatrie Solaris, Hopital Ste Marguerite, Marseille, France
Expert Opin Pharmacother 11:3053-64. 2010..Sertindole, a second-generation antipsychotic with high affinity for dopamine D₂, serotonin 5-HT₂(A), 5-HT₂(C), and α₁-adrenergic receptors, is the first phenylindole-derived antipsychotic agent...
A double-blind comparative study of clozapine and risperidone in the management of severe chronic schizophreniaJ M Azorin
French Canadian Clozapine Study Group, Hôpital St Marguerite, 270 Boulevard Ste Marguerite, 13274 Marseille Cedex 09, France
Am J Psychiatry 158:1305-13. 2001..This prospective, double-blind, multicenter, parallel-group study compared the efficacy and safety of therapeutic doses of clozapine and risperidone in patients with severe chronic schizophrenia and poor previous treatment response...
Acute phase of schizophrenia: impact of atypical antipsychoticsJ M Azorin
Service de Psychiatrie, Hopital Ste Marguerite, Marseilles, France
Int Clin Psychopharmacol 15:S5-9. 2000..The onset of action of amisulpride appears more rapid than that of haloperidol. Amisulpride therefore fulfils all the requirements of a first-line agent for the treatment of the acute phase of schizophrenia...
Trait-related decision-making impairment in the three phases of bipolar disorderMarc Adida
Mediterranean Institute of Cognitive Neurosciences, Department of Pharmacology and Neuropsychology of Emotions Related to Risk Taking and Reward, National Research Scientific Centre, Sainte Marguerite Hospital, Mediterranean University, Marseille, France
Biol Psychiatry 70:357-65. 2011..We predicted that manic, depressed, and euthymic bipolar patients (BPs) would display impaired decision-making, and we tested whether clinical characteristics could predict patients' decision-making performance...
Stroop and emotional Stroop interference in unaffected relatives of patients with schizophrenic and bipolar disorders: distinct markers of vulnerability?Nathalie Besnier
pôle de psychiatrie, Hopital Sainte Marguerite, Marseille, France
World J Biol Psychiatry 10:809-18. 2009....
Differential responses to emotional interference in paranoid schizophrenia and bipolar maniaNathalie Besnier
Pôle Universitaire de Psychiatrie Adultes, CHU Sainte Marguerite, Marseille, France
Psychopathology 44:1-11. 2011....
Evaluation of patients on sertindole treatment after failure of other antipsychotics: a retrospective analysisJean Michel Azorin
Department of Psychiatry, CHU Sainte Marguerite, Marseilles, France
BMC Psychiatry 8:16. 2008..The purpose of this study was to determine if a subset of patients with psychotic illness exists which particularly benefits from sertindole treatment after failure of other antipsychotic drugs, including atypical antipsychotics...
Risperidone versus haloperidol for facial affect recognition in schizophrenia: findings from a randomised studyEric Fakra
Department of Psychiatry, University of Marseille, Marseille, France
World J Biol Psychiatry 10:719-28. 2009..We conclude that risperidone may specifically act on the processing of emotion-laden information...
[Selecting material to develop an emotional Stroop test adapted to schizophrenia and bipolar disorders]Nathalie Besnier
Service du Pr Azorin, SHU de Psychiatrie Adultes, Hopital Sainte Marguerite, Marseille, France
Can J Psychiatry 53:177-88. 2008..This study aims to develop a version of the emotional Stroop test adapted to paranoid schizophrenia and bipolar disorder...
Blunted activation in right ventrolateral prefrontal cortex during motor response inhibition in schizophreniaArthur Kaladjian
Equipe Imagerie Cérébrale en Psychiatrie, CNRS, IFR 131, Marseille, France
Schizophr Res 97:184-93. 2007....
Rates and correlates of employment in people with schizophrenia in the UK, France and GermanySteven Marwaha
Department of Mental Health Sciences, Royal Free and University College London Medical School, 48 Riding House Street, London W1W 7EY, UK, and Psychiatrie Adultes, Hospital Sainte Marguerite, Marseille, France
Br J Psychiatry 191:30-7. 2007..Little is known about international variations in employment rates among people with schizophrenia or about the factors associated with employment in this disorder...
A double-blind, controlled study of sertindole versus risperidone in the treatment of moderate-to-severe schizophreniaJean Michel Azorin
Hopital Sainte Marguerite, Service de Psychiatrie, Marseille, France
Int Clin Psychopharmacol 21:49-56. 2006..05). In conclusion, sertindole was well tolerated and demonstrated clinically relevant efficacy advantages over risperidone...
[A randomized controlled study on the impact of pharmacoeducation on a French patient population with schizophrenic and schizoaffective disorders]Muriele Maurel
Pôle Universitaire de Psychiatrie Adultes, Centre hospitalier universitaire Sainte Marguerite, Marseille, France
Can J Psychiatry 55:329-37. 2010..To evaluate the impact of a pharmacoeducation module both on hospital stay and on clinical and functional state in a French patient population with schizophrenic and schizoaffective disorders...
The mood-instability hypothesis in the origin of mood-congruent versus mood-incongruent psychotic distinction in mania: validation in a French National Study of 1090 patientsJean Michel Azorin
Ste Marguerite Hospital, University of Marseilles, Marseilles, France
J Affect Disord 96:215-23. 2006..Although included in successive editions of the DSM since its introduction in the IIIrd, the subtyping of manic episode into 'with mood-congruent (MCP) versus mood-incongruent (MIP) psychotic features' is yet to be fully validated...
Impact of switching or initiating antipsychotic treatment on body weight during a 6-month follow-up in a cohort of patients with schizophreniaJean Pierre Schuster
Assistance Publique Hopitaux de Paris, Department of Psychiatry, Corentin Celton Hospital, Issy les Moulineaux, France
J Clin Psychopharmacol 32:672-7. 2012..We aimed to evaluate the impact of switching antipsychotics on body mass index (BMI) during a 6-month follow-up period in a large cohort of patients with schizophrenia...
Lack of insight may predict impaired decision making in manic patientsMarc Adida
Centre National de la Recherche Scientifique, IFR131, Equipe Imagerie Cérébrale en Psychiatrie, University Department of Psychiatry, SOLARIS, Sainte Marguerite Hospital, Marseille, France
Bipolar Disord 10:829-37. 2008..The aim of this study was to establish whether this characteristic can be quantified with a laboratory measure of decision making [the Iowa Gambling Task (IGT)] and to determine clinical correlates of the IGT performance in mania...
Is psychosis in DSM-IV mania due to severity? The relevance of selected demographic and comorbid social-phobic featuresJ M Azorin
Ste Marguerite Hospital, University of Marseilles, Marseilles, France
Acta Psychiatr Scand 115:29-34. 2007..We tested whether factors other than episode severity contributed to psychosis in mania...
Clinical and psychometric characterization of depression in mixed mania: a report from the French National Cohort of 1090 manic patientsE G Hantouche
Mood Center, Adult Psychiatry Department, Pitie Salpetriere Hospital, 47 bd de l Hopital, 75013 Paris Cedex 13, France
J Affect Disord 96:225-32. 2006..This work eventually led to the Kraepelinian synthesis of all manic, mixed, and depressive states into the unitary rubric of "manic-depressive insanity (1899/1921)...
Body mass index and prevalence of obesity in a French cohort of patients with schizophreniaF Limosin
Department of Psychiatry, University of Reims, Reims, France
Acta Psychiatr Scand 118:19-25. 2008..To evaluate the distributions of body mass index in a large sample of patients with schizophrenia, and to examine the association between body weight and antipsychotic drugs...
Clozapine for the treatment of schizophreniaEric Fakra
Pôle Universitaire de Psychiatrie Solaris, Hopital Sainte Marguerite, Marseille, France
Expert Opin Pharmacother 13:1923-35. 2012..Experience with clozapine should therefore be included in the education of future physicians...
Mixed states vs. pure mania in the French sample of the EMBLEM study: results at baseline and 24 months--European mania in bipolar longitudinal evaluation of medicationJean Michel Azorin
Neurosciences Medical department, Eli Lilly and Company, Suresnes, France
BMC Psychiatry 9:33. 2009..To describe the clinical course and treatment patterns over 24 months of patients experiencing an acute manic/mixed episode within the standard course of care...
Relapse according to antipsychotic treatment in schizophrenic patients: a propensity-adjusted analysisAurelie Millier
Department of Public Health, EA 3279 Research Unit, University Hospital, Boulevard Jean Moulin 13385 Marseille, France
BMC Psychiatry 11:24. 2011..To compare the rate of relapse as a function of antipsychotic treatment (monotherapy vs. polypharmacy) in schizophrenic patients over a 2-year period...
[Affective disorders and antidepressant drugs: Therapeutic innovations]E Fakra
pôle universitaire de psychiatrie, Hôpital S te Marguerite, 270 bd de S te Marguerite, 13274 Marseille Cedex 09, France
Encephale 36:S183-7. 2010..It thus seems that antidepressant agents have the ability to opposite the impact of stress through molecular actions, which directly or indirectly influence neuroplasticity...
[Bipolar disorder: Continuity from child to adult?]D Da Fonseca
Service de Pédopsychiatrie, Bd Sainte Marguerite 13009 Marseille, France
Encephale 36:S173-7. 2010..Studies on the childhood of bipolar adults, as well as studies on the children of bipolar parents will be reviewed, in an attempt to identify the psychopathological substrates of bipolar disorders...
[Affective disorders, antipsychotics and mood stabilizers: Therapeutic innovations]M Adida
pôle universitaire de psychiatrie, Hôpital S te Marguerite, 13274 Marseille Cedex 09, France
Encephale 36:S188-96. 2010....
[Affective disorders and repetitive transcranial magnetic stimulation: Therapeutic innovations]R Richieri
pôle universitaire de psychiatrie, Hôpital S te Marguerite, 270 Bd Sainte Marguerite, 13274 Marseille Cedex 09, France
Encephale 36:S197-201. 2010..Nevertheless it demonstrates the importance of developing maintenance protocols to maintain the clinical improvement achieved at the end of the acute treatment. New techniques to improve the effectiveness of rTMS are already appearing...
[Bipolar affective disorders: Models and assessment of psychological treatments]M Maurel
pôle universitaire de psychiatrie, Hôpital S te Marguerite, 270 bd de S te Marguerite 13274 Marseille cedex 9
Encephale 36:S202-5. 2010..These robust and corroborating results should probably be integrated in future guidelines for the management of bipolar disorders...
[Psychometric properties of the Activities Daily Life Scale (ADL)]L Boyer
pôle de santé publique, Hopital La Timone, Assistance Publique Hopitaux de Marseille, 264, rue Saint Pierre, 13385 Marseille Cedex 5, France
Encephale 36:408-16. 2010..There is a pressing need for detailed examination of its performance. The aim of this study was to explore ADL psychometric properties in a sample of hospitalized patients in a psychiatric ward...
[Prodromal phase in bipolar disorder]E Fakra
pôle universitaire de psychiatrie, Hopital Ste Marguerite, 13274 Marseille Cedex 09
Encephale 36:S8-12. 2010....
[Manic polarity of the onset episode of bipolar disorder: clinical and prognostic considerations]A Kaladjian
pôle universitaire de psychiatrie, SHU Psychiatrie Adultes, Hopital Ste Marguerite, 13274 Marseille cedex 9 France
Encephale 36:S13-7. 2010....
[In Alzheimer's disease, the clinical expression of behavioral and psychological signs and symptoms is early and specific of neuropathological stages]B F Michel
Unité de Neurogériatrie, Hopital Sainte Marguerite, 270, boulevard de Sainte Marguerite, 13009 Marseille, France
Encephale 36:314-25. 2010..The early diagnosis of Alzheimer's disease is a new challenge. This study concerns 50 patients, 34 females (68 %) and 16 males (32 %) with Alzheimer (AD), according to NINCDS-ADRDA diagnostic criteria...
Effect of risperidone versus haloperidol on emotional responding in schizophrenic patientsE Fakra
CIC UPCET et Pharmacologie Clinique, Hopital de la Timone, UMR CNRS 6193 Institut des Neurosciences Cognitives de la Méditerranée, Marseille, France
Psychopharmacology (Berl) 200:261-72. 2008..However, studies have rarely controlled the nature of antipsychotic medication. Yet, the influence of these drugs on emotional response is uncertain and could vary depending on their pharmacological profile...
[Depressive onset episode of bipolar disorder: clinical and prognostic considerations]N Besnier
Pôle de Psychiatrie Adultes, CHU Sainte Marguerite, 13009 Marseille
Encephale 36:S18-22. 2010..The impact of a high risk of bipolarity on drug prescription is unclear ; however, one can strongly recommend to intensifying clinical monitoring and to proposing adjunctive psychoeducation...
[Depression and circadian rhythm]J M Azorin
Hopital Sainte Marguerite, Service de Psychiatrie Adulte, 270, Bld Sainte Marguerite, 13274 Marseille Cedex 9
Encephale 35:S68-71. 2009..The question determining whether these adverse changes are a cause or effect of depressive behaviour is unresolved...
[Treatment of a first manic episode]M Maurel
Pôle de Psychiatrie Adultes, CHU Sainte Marguerite, 13009 Marseille
Encephale 36:S23-6. 2010..Clinical studies are needed in order to provide more information about the most suitable preventative treatment in this population...
Possible new ways in the pharmacological treatment of bipolar disorder and comorbid alcoholismJean Michel Azorin
Department of Psychiatry, CHU Sainte Marguerite, Marseilles, France
Neuropsychiatr Dis Treat 6:37-46. 2010..In conclusion, randomized, controlled research is still needed to provide guidelines for possible use of valproate and other agents in patients with a dual diagnosis of bipolar disorder and substance abuse or dependence...
Possible involvement of the dopamine D3 receptor locus in subtypes of bipolar affective disorderP Chiaroni
Service de Psychiatrie 2, CHU Timone, Marseille, France
Psychiatr Genet 10:43-9. 2000..01) was then noted, the bipolar females being preferentially heterozygous, and the males homozygous. These results could involve the dopamine D3 receptor locus as a minor effect gene in the manic depression condition...
Reduced brain activation in euthymic bipolar patients during response inhibition: an event-related fMRI studyArthur Kaladjian
CNRS, IFR 131, Equipe Imagerie Cérébrale en Psychiatrie, Marseille, France
Psychiatry Res 173:45-51. 2009..Further research should ascertain the role that such deficits may play in the emergence of impulsive behaviors that characterize bipolar disorder...
Valproate use in children and adolescents with bipolar disorderJean Michel Azorin
Hopital de Sainte Marguerite, Marseille, France
CNS Drugs 21:1019-33. 2007..Furthermore, clinical studies are required to clarify the efficacy and tolerability profile of valproate in comparison with other agents used in paediatric and adolescent bipolar disorder...
The cyclothymic temperament in healthy controls and familially at risk individuals for mood disorder: endophenotype for genetic studies?Pierre Chiaroni
Service de Psychiatrie, Hopital Sainte Marguerite, Bd Sainte Marguerite, 13009 Marseille, France
J Affect Disord 85:135-45. 2005..As bipolar disorder is a familial illness, an examination of cyclothymic temperament (CT) in controls and relatives of bipolar patients is of major relevance...
Insight in schizophrenia: from conceptualization to neuroscienceMounir Ouzir
Laboratory of Clinical Neuroscience and Mental Health, Faculty of Medicine and Pharmacy, Casablanca, Morocco
Psychiatry Clin Neurosci 66:167-79. 2012..The extensive literature on the cognitive consequences of lack of insight and the contribution of neuroimaging techniques to elucidating neurological etiology of insight deficits, is also reviewed...
A differential role for interleukin-6 and tumor necrosis factor-alpha in schizophrenia?J Naudin
service hospitalo universitaire de psychiatrie, CHU Sainte Marguerite, Marseille, France
Schizophr Res 26:227-33. 1997..e. illness duration. These data suggest a specific cytokine-mediated syndrome in schizophrenia. We hypothesize that TNF alpha and IL-6 reflect the genetic background of disease suceptibility...
Residential area and social contacts in schizophrenia. Results from the European Schizophrenia Cohort (EuroSC)Georg Schomerus
Dept of Psychiatry, Leipzig University, Johannisallee 20, 04317, Leipzig, Germany
Soc Psychiatry Psychiatr Epidemiol 42:617-22. 2007..Social isolation is associated with poor prognosis in schizophrenia. We aim to determine the effect of rural or urban residence on frequency of social and family contacts...
Correlates of subjective quality of life in people with schizophrenia: findings from the EuroSC studySteven Marwaha
Department of Mental Health Sciences, Royal Free and University College London Medical School, University College London, London, United Kingdom
J Nerv Ment Dis 196:87-94. 2008..Differences in mental health service provision in the United Kingdom and Germany may in part explain variations in the QOL of people with schizophrenia resident there...
The European sertindole safety and exposure survey: a follow-up study of 8600 patientsJoseph Peuskens
University Psychiatric Centre, Campus St Jozef Kortenberg, Katholieke Universiteit Leuven, Leuven, Belgium
Pharmacoepidemiol Drug Saf 16:804-11. 2007..A regulatory signal suggested that sertindole was associated with a 10-fold increased risk of death. This observational study aimed to identify deaths and their causes in patients treated with sertindole...
A prospective study of Quality of life in schizophrenia in three European countriesDirk Heider
Department of Psychiatry, University of Leipzig, Johannisalle 20, 04317 Leipzig, Germany
Schizophr Res 93:194-202. 2007..However, changes in individual's characteristics and circumstances did not relate as strongly as expected to changes in QoL, suggesting effective intervention may be difficult...
The European Schizophrenia Cohort (EuroSC): a naturalistic prognostic and economic studyPaul E Bebbington
Dept Mental Health Sciences Bloomsbury Campus, Royal Free and University College Medical School, UCL, London, W1W 7EY, UK
Soc Psychiatry Psychiatr Epidemiol 40:707-17. 2005..Secondary objectives include the assessment of treatment needs in relation to outcome, the calculation of resource consumption associated with different methods of care, and the identification of prognostic factors...
The architecture of cognitive control in schizophreniaValerian Chambon
Centre de Neuroscience Cognitive, Universite de Lyon, Lyon, France
Brain 131:962-70. 2008....
Validating antidepressant-associated hypomania (bipolar III): a systematic comparison with spontaneous hypomania (bipolar II)Hagop S Akiskal
International Mood Center, University of California at San Diego and VA Psychiatry Service (116-A, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
J Affect Disord 73:65-74. 2003..These considerations argue for revisions of DSM-IV and ICD-10 conventions. BP-HAA may represent a genetically less penetrant expression of BP-II; phenotypically; it might provisionally be categorized as bipolar III...
Burden on caregivers of people with schizophrenia: comparison between Germany and BritainChristiane Roick
Department of Psychiatry, University of Leipzig, Leipzig, Germany
Br J Psychiatry 190:333-8. 2007..Burden on the relatives of patients with schizophrenia may be influenced not only by patient and caregiver characteristics, but also by differences in mental health service provision...
