Laurent Kuras

Summary

Affiliation: Avenue de la Terrasse
Country: France

Publications

  1. pmc Association of the Mediator complex with enhancers of active genes
    Laurent Kuras
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette, France
    Proc Natl Acad Sci U S A 100:13887-91. 2003
  2. pmc Independent recruitment of mediator and SAGA by the activator Met4
    Christophe Leroy
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette, France
    Mol Cell Biol 26:3149-63. 2006
  3. pmc Transcriptional plasticity through differential assembly of a multiprotein activation complex
    Laëtitia Cormier
    CNRS, Centre de Genetique Moleculaire, Gif sur Yvette, France
    Nucleic Acids Res 38:4998-5014. 2010
  4. pmc Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo
    Thierry Lacombe
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, affiliated with Université Paris Sud, Gif sur Yvette 91198, France
    Nucleic Acids Res 41:9651-62. 2013
  5. ncbi request reprint Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment
    Laurent Kuras
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, 91198 Gif sur Yvettte, France
    Mol Cell 10:69-80. 2002
  6. ncbi request reprint Characterization of protein-DNA association in vivo by chromatin immunoprecipitation
    Laurent Kuras
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Methods Mol Biol 284:147-62. 2004
  7. pmc Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae
    Joseph V Geisberg
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell Biol 22:8122-34. 2002
  8. ncbi request reprint A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II
    Henri Marc Bourbon
    Mol Cell 14:553-7. 2004
  9. ncbi request reprint Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast
    Mario Mencía
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 9:823-33. 2002

Collaborators

Detail Information

Publications9

  1. pmc Association of the Mediator complex with enhancers of active genes
    Laurent Kuras
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette, France
    Proc Natl Acad Sci U S A 100:13887-91. 2003
    ..These findings support the idea of Mediator as a primary conduit of regulatory information from enhancers to promoters in eukaryotic cells...
  2. pmc Independent recruitment of mediator and SAGA by the activator Met4
    Christophe Leroy
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, 91198 Gif sur Yvette, France
    Mol Cell Biol 26:3149-63. 2006
    ..Interestingly, we find that SAGA is not required for Mediator recruitment by Met4 and vice versa. Our results provide a novel example of functional interplay between Mediator and coactivators involved in histone modification...
  3. pmc Transcriptional plasticity through differential assembly of a multiprotein activation complex
    Laëtitia Cormier
    CNRS, Centre de Genetique Moleculaire, Gif sur Yvette, France
    Nucleic Acids Res 38:4998-5014. 2010
    ..We also show evidence suggesting that integration of PDC6 to the Met4 regulon may have occurred recently in the evolution of the Saccharomyces cerevisiae lineage...
  4. pmc Mediator is an intrinsic component of the basal RNA polymerase II machinery in vivo
    Thierry Lacombe
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, affiliated with Université Paris Sud, Gif sur Yvette 91198, France
    Nucleic Acids Res 41:9651-62. 2013
    ..Our results strongly support that Mediator is an integral component of the minimal machinery essential in vivo for stable Pol II association with the promoter. ..
  5. ncbi request reprint Dual regulation of the met4 transcription factor by ubiquitin-dependent degradation and inhibition of promoter recruitment
    Laurent Kuras
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, 91198 Gif sur Yvettte, France
    Mol Cell 10:69-80. 2002
    ....
  6. ncbi request reprint Characterization of protein-DNA association in vivo by chromatin immunoprecipitation
    Laurent Kuras
    Centre de Genetique Moleculaire, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Methods Mol Biol 284:147-62. 2004
    ..The ChIP method described here is intended for studying protein-DNA association in the budding yeast Saccharomyces cerevisiae, but it can be easily implemented in other cell types, including fly, mammalian, and plant cells...
  7. pmc Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae
    Joseph V Geisberg
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA
    Mol Cell Biol 22:8122-34. 2002
    ..We speculate that Mot1 does not form transcriptionally active TBP complexes but rather regulates transcription in vivo by modulating the activity of free TBP and/or by affecting promoter DNA structure...
  8. ncbi request reprint A unified nomenclature for protein subunits of mediator complexes linking transcriptional regulators to RNA polymerase II
    Henri Marc Bourbon
    Mol Cell 14:553-7. 2004
  9. ncbi request reprint Activator-specific recruitment of TFIID and regulation of ribosomal protein genes in yeast
    Mario Mencía
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    Mol Cell 9:823-33. 2002
    ..These results demonstrate activator-specific recruitment of TFIID in vivo, and they suggest that TFIID recruitment is important for coordinate expression of RP genes...