Mehdi Kabani

Summary

Affiliation: Avenue de la Terrasse
Country: France

Publications

  1. pmc Multiple hsp70 isoforms in the eukaryotic cytosol: mere redundancy or functional specificity?
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales LEBS, CNRS, Bat 34, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    Curr Genomics 9:338-248. 2008
  2. doi request reprint Yeast prions assembly and propagation: contributions of the prion and non-prion moieties and the nature of assemblies
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Prion 5:277-84. 2011
  3. ncbi request reprint Structural and functional diversity among eukaryotic Hsp70 nucleotide exchange factors
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, 91198 Gif sur Yvette, France
    Protein Pept Lett 16:623-60. 2009
  4. doi request reprint A mutation within the C-terminal domain of Sup35p that affects [PSI+] prion propagation
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, Bat 34, Avenue de la Terrasse, F 91190 Gif sur Yvette, France
    Mol Microbiol 81:640-58. 2011
  5. doi request reprint Swa2p-dependent clathrin dynamics is critical for Flo11p processing and 'Mat' formation in the yeast Saccharomyces cerevisiae
    Céline N Martineau
    Laboratoire d Enzymologie et Biochimie Structurales LEBS, CNRS, Gif sur Yvette, France
    FEBS Lett 584:1149-55. 2010
  6. pmc Hsc70 protein interaction with soluble and fibrillar alpha-synuclein
    Samantha Pemberton
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, 91198 Gif sur Yvette, France
    J Biol Chem 286:34690-9. 2011
  7. pmc Flo11p-independent control of "mat" formation by hsp70 molecular chaperones and nucleotide exchange factors in yeast
    Céline N Martineau
    Laboratoire de Microbiologie et Genetique Moleculaire, CNRS, INRA, AgroParisTech, 78850 Thiverval Grignon, France
    Genetics 177:1679-89. 2007
  8. pmc Molecular and functional characterization of the only known hemiascomycete ortholog of the carboxyl terminus of Hsc70-interacting protein CHIP in the yeast Yarrowia lipolytica
    Céline N Martineau
    Laboratoire d Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Cell Stress Chaperones 17:229-41. 2012
  9. doi request reprint A role for the proteasome in the turnover of Sup35p and in [PSI(+) ] prion propagation
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, Bat 34, Avenue de la Terrasse, F 91190, Gif sur Yvette, France
    Mol Microbiol 92:507-28. 2014

Collaborators

  • Virginie Redeker
  • Celine Fabret
  • Céline N Martineau
  • Ronald Melki
  • Samantha Pemberton
  • Jean Marie Beckerich
  • Marie Thérèse Le Dall
  • Karine Madiona
  • Luc Bousset
  • Laura Pieri

Detail Information

Publications9

  1. pmc Multiple hsp70 isoforms in the eukaryotic cytosol: mere redundancy or functional specificity?
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales LEBS, CNRS, Bat 34, Avenue de la Terrasse, 91198 Gif sur Yvette, France
    Curr Genomics 9:338-248. 2008
    ..We summarize here our current knowledge of the functions and regulations of these molecular chaperones, and shed light on the known functional specificities among isoforms...
  2. doi request reprint Yeast prions assembly and propagation: contributions of the prion and non-prion moieties and the nature of assemblies
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Prion 5:277-84. 2011
    ....
  3. ncbi request reprint Structural and functional diversity among eukaryotic Hsp70 nucleotide exchange factors
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, 91198 Gif sur Yvette, France
    Protein Pept Lett 16:623-60. 2009
    ..Here, I summarize our current knowledge of their mechanisms of action, regulations and cellular functions as well as their relevance for human diseases such as cystic fibrosis or amyloidoses...
  4. doi request reprint A mutation within the C-terminal domain of Sup35p that affects [PSI+] prion propagation
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, Bat 34, Avenue de la Terrasse, F 91190 Gif sur Yvette, France
    Mol Microbiol 81:640-58. 2011
    ..Our results clearly demonstrate that Sup35p C-terminal domain plays a critical role in prion propagation and provide new insights into the mechanism of prion conversion...
  5. doi request reprint Swa2p-dependent clathrin dynamics is critical for Flo11p processing and 'Mat' formation in the yeast Saccharomyces cerevisiae
    Céline N Martineau
    Laboratoire d Enzymologie et Biochimie Structurales LEBS, CNRS, Gif sur Yvette, France
    FEBS Lett 584:1149-55. 2010
    ..Both the TPR and J-domains of Swa2p, but not its clathrin-binding and ubiquitin-association motifs, are required for its function in Flo11p processing...
  6. pmc Hsc70 protein interaction with soluble and fibrillar alpha-synuclein
    Samantha Pemberton
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, 91198 Gif sur Yvette, France
    J Biol Chem 286:34690-9. 2011
    ..Hsc70 may therefore significantly affect the cellular propagation of α-Syn aggregates and their spread throughout the central nervous system in Parkinson disease...
  7. pmc Flo11p-independent control of "mat" formation by hsp70 molecular chaperones and nucleotide exchange factors in yeast
    Céline N Martineau
    Laboratoire de Microbiologie et Genetique Moleculaire, CNRS, INRA, AgroParisTech, 78850 Thiverval Grignon, France
    Genetics 177:1679-89. 2007
    ..Importantly, these mutations did not compromise invasive growth or Flo11p expression, suggesting that Flo11p-independent pathways are necessary to form mats...
  8. pmc Molecular and functional characterization of the only known hemiascomycete ortholog of the carboxyl terminus of Hsc70-interacting protein CHIP in the yeast Yarrowia lipolytica
    Céline N Martineau
    Laboratoire d Enzymologie et Biochimie Structurales, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    Cell Stress Chaperones 17:229-41. 2012
    ..Chn1p/Ssa1p interaction is Fes1p-dependent and the formation of an Yl.Chn1p/Ssa1p/Sse1p ternary complex. Finally, we show that, similar to Sse1p, Yl.Chn1p can act as a "holdase" to prevent the aggregation of a heat-denatured protein...
  9. doi request reprint A role for the proteasome in the turnover of Sup35p and in [PSI(+) ] prion propagation
    Mehdi Kabani
    Laboratoire d Enzymologie et Biochimie Structurales, CNRS, Bat 34, Avenue de la Terrasse, F 91190, Gif sur Yvette, France
    Mol Microbiol 92:507-28. 2014
    ..Our results point to an overlooked role of the proteasome in clearing toxic protein aggregates, and have important implications for a better understanding of the life cycle of infectious protein assemblies. ..